DK3142659T3 - Hiv-1 proteasehæmmere og anvendelser deraf - Google Patents

Hiv-1 proteasehæmmere og anvendelser deraf Download PDF

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Publication number
DK3142659T3
DK3142659T3 DK15792991.0T DK15792991T DK3142659T3 DK 3142659 T3 DK3142659 T3 DK 3142659T3 DK 15792991 T DK15792991 T DK 15792991T DK 3142659 T3 DK3142659 T3 DK 3142659T3
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DK
Denmark
Prior art keywords
hiv
protease inhibitors
protease
inhibitors
Prior art date
Application number
DK15792991.0T
Other languages
English (en)
Inventor
Arun K Ghosh
Venkateswara Kalapala Rao
Hiroaki Mitsuya
Original Assignee
Purdue Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Purdue Research Foundation filed Critical Purdue Research Foundation
Application granted granted Critical
Publication of DK3142659T3 publication Critical patent/DK3142659T3/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/08Bridged systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
DK15792991.0T 2014-05-16 2015-05-15 Hiv-1 proteasehæmmere og anvendelser deraf DK3142659T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201461994462P 2014-05-16 2014-05-16
PCT/US2015/031181 WO2015175994A1 (en) 2014-05-16 2015-05-15 Hiv-1 protease inhibitors and uses thereof

Publications (1)

Publication Number Publication Date
DK3142659T3 true DK3142659T3 (da) 2021-05-31

Family

ID=54480812

Family Applications (1)

Application Number Title Priority Date Filing Date
DK15792991.0T DK3142659T3 (da) 2014-05-16 2015-05-15 Hiv-1 proteasehæmmere og anvendelser deraf

Country Status (5)

Country Link
US (1) US9670225B2 (da)
EP (1) EP3142659B1 (da)
JP (1) JP6622290B2 (da)
DK (1) DK3142659T3 (da)
WO (1) WO2015175994A1 (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9670225B2 (en) 2014-05-16 2017-06-06 Purdue Research Foundation HIV-1 protease inhibitors and uses thereof
JP2018525404A (ja) * 2015-08-17 2018-09-06 パーデュー・リサーチ・ファウンデーションPurdue Research Foundation Hiv−1プロテアーゼ阻害剤およびその使用
US11028096B2 (en) 2016-11-09 2021-06-08 Purdue Research Foundation Tricyclic P2-ligand containing potent HIV-protease inhibitors against HIV/AIDS
JOP20180009A1 (ar) 2017-02-06 2019-01-30 Gilead Sciences Inc مركبات مثبط فيروس hiv
WO2019006335A1 (en) * 2017-06-30 2019-01-03 Ghosh Arun K INHIBITORS OF HIV-1 PROTEASE AND USES THEREOF
TWI829205B (zh) 2018-07-30 2024-01-11 美商基利科學股份有限公司 抗hiv化合物
WO2020150369A1 (en) * 2019-01-15 2020-07-23 Ghosh Arun K Hiv-1 protease inhibitors and uses thereof
WO2021188191A1 (en) * 2020-03-18 2021-09-23 Purdue Research Foundation Tricyclic p2-ligand containing potent hiv-protease inhibitors
US20230399338A1 (en) 2022-06-10 2023-12-14 Arun K. Ghosh METHOD OF SYNTHESIZING (3S,3AR,5R,7AS,8S)- HEXAHYDRO-4H-3,5-METHANOFURO[2,3-b]PYRAN-8-OL

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2007275689A1 (en) * 2006-07-21 2008-01-24 Gilead Sciences, Inc. AZA-peptide protease inhibitors
EP2069356A1 (en) * 2006-07-24 2009-06-17 Gilead Sciences, Inc. Bisfuranyl protease inhibitors
EP2304043A4 (en) * 2008-07-09 2012-05-30 Purdue Research Foundation HIV PROTEASE INHIBITORS AND METHOD FOR THEIR USE
CA2810005A1 (en) * 2010-09-02 2012-03-08 Purdue Research Foundation Fused tricyclic ether carbamates and their use
US9670225B2 (en) 2014-05-16 2017-06-06 Purdue Research Foundation HIV-1 protease inhibitors and uses thereof

Also Published As

Publication number Publication date
EP3142659A4 (en) 2017-09-27
JP2017515914A (ja) 2017-06-15
US20170088555A1 (en) 2017-03-30
JP6622290B2 (ja) 2019-12-18
EP3142659A1 (en) 2017-03-22
WO2015175994A1 (en) 2015-11-19
US9670225B2 (en) 2017-06-06
EP3142659B1 (en) 2021-03-24

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