HUE060309T2 - Májkárosító hatástól mentes új acetaminofen vegyület - Google Patents
Májkárosító hatástól mentes új acetaminofen vegyületInfo
- Publication number
- HUE060309T2 HUE060309T2 HUE13897632A HUE13897632A HUE060309T2 HU E060309 T2 HUE060309 T2 HU E060309T2 HU E13897632 A HUE13897632 A HU E13897632A HU E13897632 A HUE13897632 A HU E13897632A HU E060309 T2 HUE060309 T2 HU E060309T2
- Authority
- HU
- Hungary
- Prior art keywords
- liver
- side effect
- compound composition
- acetaminophen compound
- new
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/765—Polymers containing oxygen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/46—Ingredients of undetermined constitution or reaction products thereof, e.g. skin, bone, milk, cotton fibre, eggshell, oxgall or plant extracts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Inorganic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Botany (AREA)
- Toxicology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Rheumatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/CN2013/087049 WO2015070396A1 (zh) | 2013-11-13 | 2013-11-13 | 无肝副作用的对乙酰胺基酚新复方组合 |
EP13897632.9A EP3069733B1 (en) | 2013-11-13 | 2013-11-13 | New acetaminophen compound composition without side effect to liver |
Publications (1)
Publication Number | Publication Date |
---|---|
HUE060309T2 true HUE060309T2 (hu) | 2023-02-28 |
Family
ID=53056618
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HUE13897632A HUE060309T2 (hu) | 2013-11-13 | 2013-11-13 | Májkárosító hatástól mentes új acetaminofen vegyület |
Country Status (15)
Country | Link |
---|---|
US (3) | US10420737B2 (hu) |
EP (2) | EP3069733B1 (hu) |
JP (1) | JP2016520100A (hu) |
KR (2) | KR102017550B1 (hu) |
CN (2) | CN111904924A (hu) |
DK (1) | DK3069733T3 (hu) |
EA (1) | EA029454B1 (hu) |
ES (1) | ES2929945T3 (hu) |
HR (1) | HRP20221344T1 (hu) |
HU (1) | HUE060309T2 (hu) |
LT (1) | LT3069733T (hu) |
PL (1) | PL3069733T3 (hu) |
PT (1) | PT3069733T (hu) |
RS (1) | RS63704B1 (hu) |
WO (1) | WO2015070396A1 (hu) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR102017550B1 (ko) * | 2013-11-13 | 2019-09-03 | 내셔널 디펜스 에듀케이션 앤드 리서치 파운데이션 | 간에 대한 부작용이 없는 신규의 아세트아미노펜 화합물 조성물 |
BR112018005905B1 (pt) * | 2015-09-24 | 2023-03-21 | Sinew Pharma Inc | Composto, composição farmacêutica, e, uso de um composto |
US10925854B2 (en) * | 2015-11-19 | 2021-02-23 | Sinew Pharma Inc. | Methods and compositions for preventing or treating fatty liver, protecting liver function or ameliorating liver diseases caused by fatty liver or other associated disorders |
SG11202007314QA (en) * | 2018-02-14 | 2020-08-28 | Sinew Pharma Inc | Methods and compositions for preventing, reducing or eradicating toxicity caused by acetaminophen (apap) |
JP6858729B2 (ja) * | 2018-05-25 | 2021-04-14 | ▲財▼▲団▼法人国防教育研究基金会National Defense Education And Research Foundation | 肝臓に対する副作用がない、新しいアセトアミノフェン複合組成 |
EP3846815A4 (en) * | 2018-09-03 | 2022-05-04 | Jacob Biotech Ltd | PHARMACEUTICAL PREPARATIONS OF SEBACOYL-DINALBUPHINE AND ACETAMINOPHEN AND METHODS FOR PAIN MANAGEMENT |
Family Cites Families (48)
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JPS5584166A (en) * | 1978-12-20 | 1980-06-25 | Lion Hamigaki Kk | Band for spongy medicine |
ZA837556B (en) * | 1982-11-15 | 1984-06-27 | Upjohn Co | Acetominophen and ibuprofen/flurbiprofen |
JPS62502194A (ja) * | 1985-03-18 | 1987-08-27 | プロダクト・リソ−シズ・インタ−ナショナル・インコ−ポレイテッド | エ−ロゾル発泡体 |
AU589991B2 (en) * | 1985-08-26 | 1989-10-26 | G.D. Searle & Co. | Taste masking compositions |
JPH01190628A (ja) * | 1988-01-21 | 1989-07-31 | Sumitomo Pharmaceut Co Ltd | 持続性坐剤 |
FR2646773B1 (fr) * | 1989-05-12 | 1994-05-13 | Chauvin Sa Laboratoire | Composition pharmaceutique a base de paracetamol |
JP3165438B2 (ja) * | 1990-04-04 | 2001-05-14 | バーウィンド・ファーマス―ティカル・サーヴィスィーズ・インコーポレーテッド | 水性のマルトデキストリン及びセルロースポリマーフィルムコーティング |
DE69425453T2 (de) * | 1993-04-23 | 2001-04-12 | Novartis Ag, Basel | Wirkstoffabgabevorrichtung mit gesteuerter Freigabe |
US5733578A (en) * | 1995-11-15 | 1998-03-31 | Edward Mendell Co., Inc. | Directly compressible high load acetaminophen formulations |
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US5858997A (en) * | 1997-12-04 | 1999-01-12 | Chesebrough-Pond's Usa Co., Division Of Conopco, Inc. | Method and composition for skin lightening |
US8524277B2 (en) * | 1998-03-06 | 2013-09-03 | Alza Corporation | Extended release dosage form |
ES2153786B1 (es) * | 1999-06-10 | 2001-10-16 | S A L V A T Lab Sa | Composicion farmaceutica liquida para la administracion oral de principios activos amargos y susceptibles de hidrolisis. |
FR2798289B1 (fr) * | 1999-09-15 | 2004-12-31 | Cll Pharma | Formes galeniques a delitement rapide en bouche et leur procede de preparation |
IL149282A (en) * | 1999-10-29 | 2010-05-31 | Fmc Corp | Edible coating composition |
ES2174734B1 (es) * | 2000-11-03 | 2003-10-01 | Belmac S A Lab | Nueva formulacion galenica de paracetamol dispersable y soluble, procedimiento para su preparacion y aplicaciones. |
CA2448558A1 (en) * | 2001-07-10 | 2003-01-23 | Teva Pharmaceutical Industries, Ltd. | Drug delivery system for zero order, zero order-biphasic, ascending or descending drug delivery |
BR0211794A (pt) * | 2001-07-31 | 2004-11-03 | Wyeth Corp | Composição farmacêutica e método para mascarar o sabor de pelo menos um composto farmaceuticamente ativo de sabor desagradável |
US7101572B2 (en) * | 2001-12-07 | 2006-09-05 | Unilab Pharmatech, Ltd. | Taste masked aqueous liquid pharmaceutical composition |
KR100522239B1 (ko) * | 2002-07-16 | 2005-10-18 | 주식회사 서울제약 | 아세트아미노펜을 함유하는 제어방출성의 경구용 제제 |
KR100507771B1 (ko) * | 2002-11-08 | 2005-08-17 | 한미약품 주식회사 | 난용성 감기약 활성 성분의 경구투여용 조성물 및 그의제조 방법 |
CA2540059C (en) * | 2003-09-26 | 2013-08-06 | Alza Corporation | Controlled release formulations exhibiting an ascending rate of release |
ATE544447T1 (de) * | 2003-09-26 | 2012-02-15 | Alza Corp | Arzneistoffcoating mit hohem wirkstoffanteil sowie methoden zu dessen herstellung |
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CN101695498A (zh) * | 2009-10-26 | 2010-04-21 | 昆明理工大学 | 对乙酰氨基酚所致肝损伤保护药物及其应用 |
CA2706272C (en) * | 2010-06-03 | 2020-05-05 | Accucaps Industries Limited | Multi phase soft gel capsules, apparatus and method thereof |
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CN108465110A (zh) * | 2011-04-20 | 2018-08-31 | 教育研究基金会 | 无/低副作用的抗结核病药物复方 |
CN102988993B (zh) * | 2011-09-13 | 2017-03-15 | 广东九明制药有限公司 | 复方对乙酰氨基酚片主要辅料的筛选和组成及其制备方法 |
JP5828280B2 (ja) * | 2011-12-28 | 2015-12-02 | ライオン株式会社 | 錠剤及びその製造方法 |
ES2414557B1 (es) | 2012-01-16 | 2014-06-10 | Novocat Farma, S.A. | Composición acuosa de paracetamol para inyección |
CN102600119B (zh) * | 2012-02-07 | 2013-03-27 | 海南卫康制药(潜山)有限公司 | 一种小儿对乙酰氨基酚组合物 |
CN103110629B (zh) * | 2013-02-19 | 2014-03-19 | 青岛正大海尔制药有限公司 | 复方酚麻美敏滴丸及其制备方法 |
KR102017550B1 (ko) * | 2013-11-13 | 2019-09-03 | 내셔널 디펜스 에듀케이션 앤드 리서치 파운데이션 | 간에 대한 부작용이 없는 신규의 아세트아미노펜 화합물 조성물 |
BR112018005905B1 (pt) * | 2015-09-24 | 2023-03-21 | Sinew Pharma Inc | Composto, composição farmacêutica, e, uso de um composto |
SG11202007314QA (en) * | 2018-02-14 | 2020-08-28 | Sinew Pharma Inc | Methods and compositions for preventing, reducing or eradicating toxicity caused by acetaminophen (apap) |
-
2013
- 2013-11-13 KR KR1020177019405A patent/KR102017550B1/ko active IP Right Grant
- 2013-11-13 LT LTEPPCT/CN2013/087049T patent/LT3069733T/lt unknown
- 2013-11-13 US US14/441,317 patent/US10420737B2/en active Active
- 2013-11-13 HR HRP20221344TT patent/HRP20221344T1/hr unknown
- 2013-11-13 HU HUE13897632A patent/HUE060309T2/hu unknown
- 2013-11-13 RS RS20221004A patent/RS63704B1/sr unknown
- 2013-11-13 CN CN202010418123.2A patent/CN111904924A/zh active Pending
- 2013-11-13 PT PT138976329T patent/PT3069733T/pt unknown
- 2013-11-13 EP EP13897632.9A patent/EP3069733B1/en active Active
- 2013-11-13 DK DK13897632.9T patent/DK3069733T3/da active
- 2013-11-13 EP EP22183582.0A patent/EP4173619A3/en active Pending
- 2013-11-13 EA EA201591435A patent/EA029454B1/ru unknown
- 2013-11-13 ES ES13897632T patent/ES2929945T3/es active Active
- 2013-11-13 KR KR1020157023533A patent/KR101881074B1/ko active IP Right Grant
- 2013-11-13 WO PCT/CN2013/087049 patent/WO2015070396A1/zh active Application Filing
- 2013-11-13 CN CN201380058666.6A patent/CN105188756B/zh active Active
- 2013-11-13 JP JP2016515604A patent/JP2016520100A/ja active Pending
- 2013-11-13 PL PL13897632.9T patent/PL3069733T3/pl unknown
-
2019
- 2019-05-14 US US16/411,861 patent/US11534416B2/en active Active
-
2022
- 2022-11-23 US US17/993,183 patent/US20230082397A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
HRP20221344T1 (hr) | 2022-12-23 |
CN111904924A (zh) | 2020-11-10 |
US20230082397A1 (en) | 2023-03-16 |
US20190262289A1 (en) | 2019-08-29 |
EP4173619A2 (en) | 2023-05-03 |
CN105188756A (zh) | 2015-12-23 |
PL3069733T3 (pl) | 2023-02-13 |
KR102017550B1 (ko) | 2019-09-03 |
JP2016520100A (ja) | 2016-07-11 |
RS63704B1 (sr) | 2022-11-30 |
EP3069733A4 (en) | 2017-08-23 |
EP3069733B1 (en) | 2022-08-10 |
CN105188756B (zh) | 2020-06-12 |
ES2929945T3 (es) | 2022-12-05 |
EP4173619A3 (en) | 2023-07-19 |
US11534416B2 (en) | 2022-12-27 |
KR20150115846A (ko) | 2015-10-14 |
US10420737B2 (en) | 2019-09-24 |
KR20170085607A (ko) | 2017-07-24 |
EP3069733A1 (en) | 2016-09-21 |
DK3069733T3 (da) | 2022-11-14 |
LT3069733T (lt) | 2022-11-25 |
KR101881074B1 (ko) | 2018-08-17 |
EA201591435A1 (ru) | 2016-05-31 |
US20170172950A1 (en) | 2017-06-22 |
PT3069733T (pt) | 2022-11-09 |
EA029454B1 (ru) | 2018-03-30 |
WO2015070396A1 (zh) | 2015-05-21 |
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