HUE054882T2 - Vesesejt-populációk és alkalmazásaik - Google Patents

Vesesejt-populációk és alkalmazásaik

Info

Publication number
HUE054882T2
HUE054882T2 HUE19168775A HUE19168775A HUE054882T2 HU E054882 T2 HUE054882 T2 HU E054882T2 HU E19168775 A HUE19168775 A HU E19168775A HU E19168775 A HUE19168775 A HU E19168775A HU E054882 T2 HUE054882 T2 HU E054882T2
Authority
HU
Hungary
Prior art keywords
cell populations
renal cell
renal
populations
cell
Prior art date
Application number
HUE19168775A
Other languages
English (en)
Inventor
Joydeep Basu
Kelly Guthrie
Dominic Justewicz
Teresa Burnette
Andrew Bruce
Russell Kelley
John Ludlow
Original Assignee
Prokidney
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Prokidney filed Critical Prokidney
Publication of HUE054882T2 publication Critical patent/HUE054882T2/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0684—Cells of the urinary tract or kidneys
    • C12N5/0686—Kidney cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/22—Urine; Urinary tract, e.g. kidney or bladder; Intraglomerular mesangial cells; Renal mesenchymal cells; Adrenal gland
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0081—Purging biological preparations of unwanted cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/02—Atmosphere, e.g. low oxygen conditions
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/50—Cell markers; Cell surface determinants
    • C12N2501/58—Adhesion molecules, e.g. ICAM, VCAM, CD18 (ligand), CD11 (ligand), CD49 (ligand)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/50—Cell markers; Cell surface determinants
    • C12N2501/599—Cell markers; Cell surface determinants with CD designations not provided for elsewhere
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2509/00—Methods for the dissociation of cells, e.g. specific use of enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2509/00—Methods for the dissociation of cells, e.g. specific use of enzymes
    • C12N2509/10—Mechanical dissociation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701—Details
    • G01N2333/4742—Keratin; Cytokeratin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/91—Transferases (2.)
    • G01N2333/91045—Acyltransferases (2.3)
    • G01N2333/91074—Aminoacyltransferases (general) (2.3.2)
    • G01N2333/9108—Aminoacyltransferases (general) (2.3.2) with definite EC number (2.3.2.-)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Cell Biology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
HUE19168775A 2012-10-24 2013-10-24 Vesesejt-populációk és alkalmazásaik HUE054882T2 (hu)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261718150P 2012-10-24 2012-10-24
US201361876616P 2013-09-11 2013-09-11

Publications (1)

Publication Number Publication Date
HUE054882T2 true HUE054882T2 (hu) 2021-10-28

Family

ID=49517782

Family Applications (2)

Application Number Title Priority Date Filing Date
HUE19168775A HUE054882T2 (hu) 2012-10-24 2013-10-24 Vesesejt-populációk és alkalmazásaik
HUE13786132A HUE046176T2 (hu) 2012-10-24 2013-10-24 Vesesejt-populációk és alkalmazásaik

Family Applications After (1)

Application Number Title Priority Date Filing Date
HUE13786132A HUE046176T2 (hu) 2012-10-24 2013-10-24 Vesesejt-populációk és alkalmazásaik

Country Status (18)

Country Link
US (4) US20150246073A1 (hu)
EP (3) EP2912165B1 (hu)
JP (2) JP6509119B2 (hu)
KR (3) KR102215476B1 (hu)
CN (3) CN110184232B (hu)
AU (3) AU2013334276B2 (hu)
BR (2) BR112015009042B1 (hu)
CA (2) CA2889270A1 (hu)
DK (2) DK2912165T3 (hu)
ES (2) ES2876177T3 (hu)
HK (1) HK1215448A1 (hu)
HU (2) HUE054882T2 (hu)
NZ (2) NZ707873A (hu)
PL (2) PL3567099T3 (hu)
PT (1) PT2912165T (hu)
RU (1) RU2702721C2 (hu)
SI (1) SI2912165T1 (hu)
WO (1) WO2014066699A1 (hu)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
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ES2876177T3 (es) 2012-10-24 2021-11-12 Prokidney Poblaciones de células renales y usos de las mismas
US11123372B2 (en) * 2016-07-29 2021-09-21 Prokidney Bioactive renal cells for the treatment of chronic kidney disease
RU2019105592A (ru) * 2016-07-29 2020-08-28 Дипак ДЖАИН Биоактивные почечные клетки для лечения хронической болезни почек
CA3057498A1 (en) * 2017-03-31 2018-10-04 Deepak Jain Injectable cell and scaffold compositions
CA3065790A1 (en) * 2017-06-21 2018-12-27 Timothy A. Bertram Immunoprivileged bioactive renal cells for the treatment of kidney disease
JP7061766B2 (ja) * 2017-09-20 2022-05-02 学校法人同志社 Ｄｊ－１タンパク質産生促進用組成物
CN109266616A (zh) * 2018-08-21 2019-01-25 山西省人民医院 一种稳定表达aqp2蛋白的人源化小鼠足细胞模型及其构建方法和应用
CA3108729A1 (en) * 2018-08-31 2020-03-05 Timothy Bertram Compositions comprising cell-derived vesicles and uses thereof
AU2020266168A1 (en) * 2019-05-02 2021-12-02 Prokidney Treatment of kidney disease in subjects with kidney and/or urinary tract anomalies
WO2021152578A1 (en) * 2020-01-28 2021-08-05 Kidneycure Ltd Process for kidney cell manufacture and treatment
CN116240161B (zh) * 2023-02-27 2024-05-10 四川大学华西医院 具有肾脏损伤修复作用的细胞外囊泡制备方法及应用

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Also Published As

Publication number Publication date
BR112015009042A8 (pt) 2017-10-10
KR102460536B1 (ko) 2022-10-31
JP2016504017A (ja) 2016-02-12
HUE046176T2 (hu) 2020-02-28
ES2744979T3 (es) 2020-02-27
EP3901251A1 (en) 2021-10-27
SI2912165T1 (sl) 2019-11-29
JP2019141067A (ja) 2019-08-29
JP6696023B2 (ja) 2020-05-20
CN110184232B (zh) 2023-10-20
NZ741724A (en) 2020-02-28
US11369639B2 (en) 2022-06-28
DK2912165T3 (da) 2019-09-16
KR20150085818A (ko) 2015-07-24
CN110184232A (zh) 2019-08-30
AU2022201010A1 (en) 2022-03-03
KR102215476B1 (ko) 2021-02-17
KR102160725B1 (ko) 2020-09-29
AU2013334276B2 (en) 2019-07-04
CN104937095B (zh) 2019-06-07
EP2912165B1 (en) 2019-06-19
ES2876177T3 (es) 2021-11-12
RU2702721C2 (ru) 2019-10-09
US20200101112A1 (en) 2020-04-02
EP2912165A1 (en) 2015-09-02
BR112015009042A2 (pt) 2017-07-04
EP3567099B1 (en) 2021-04-21
BR112015009042B1 (pt) 2021-10-19
RU2015119514A (ru) 2016-12-20
US20220347221A1 (en) 2022-11-03
EP3567099A1 (en) 2019-11-13
AU2019204178B2 (en) 2021-11-18
DK3567099T3 (da) 2021-06-07
AU2019204178A1 (en) 2019-07-04
PL2912165T3 (pl) 2020-01-31
KR20200113287A (ko) 2020-10-06
AU2013334276A1 (en) 2015-05-14
US20170281684A1 (en) 2017-10-05
ES2744979T8 (es) 2020-04-28
US20150246073A1 (en) 2015-09-03
CN117660296A (zh) 2024-03-08
NZ707873A (en) 2019-01-25
KR20220150419A (ko) 2022-11-10
KR20210018965A (ko) 2021-02-18
CN104937095A (zh) 2015-09-23
BR122020018576B1 (pt) 2022-07-05
PL3567099T3 (pl) 2021-11-29
US10363274B2 (en) 2019-07-30
JP6509119B2 (ja) 2019-05-08
CA3240629A1 (en) 2014-05-01
CA2889270A1 (en) 2014-05-01
WO2014066699A1 (en) 2014-05-01
HK1215448A1 (zh) 2016-08-26
PT2912165T (pt) 2019-09-26
RU2019118791A (ru) 2019-07-11

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