ES2744979T8 - Poblaciones de células renales y usos de las mismas - Google Patents

Poblaciones de células renales y usos de las mismas

Info

Publication number
ES2744979T8
ES2744979T8 ES13786132T ES13786132T ES2744979T8 ES 2744979 T8 ES2744979 T8 ES 2744979T8 ES 13786132 T ES13786132 T ES 13786132T ES 13786132 T ES13786132 T ES 13786132T ES 2744979 T8 ES2744979 T8 ES 2744979T8
Authority
ES
Spain
Prior art keywords
cell populations
renal cell
renal
populations
cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES13786132T
Other languages
English (en)
Other versions
ES2744979T3 (es
Inventor
Joydeep Basu
Kelly Guthrie
Dominic Justewicz
Teresa Burnette
Andrew Bruce
Russell W Kelley
John W Ludlow
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Inregen Inc
Original Assignee
Inregen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inregen Inc filed Critical Inregen Inc
Application granted granted Critical
Publication of ES2744979T3 publication Critical patent/ES2744979T3/es
Publication of ES2744979T8 publication Critical patent/ES2744979T8/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/22Urine; Urinary tract, e.g. kidney or bladder; Intraglomerular mesangial cells; Renal mesenchymal cells; Adrenal gland
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0081Purging biological preparations of unwanted cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0684Cells of the urinary tract or kidneys
    • C12N5/0686Kidney cells
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966Animal cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/02Atmosphere, e.g. low oxygen conditions
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/50Cell markers; Cell surface determinants
    • C12N2501/58Adhesion molecules, e.g. ICAM, VCAM, CD18 (ligand), CD11 (ligand), CD49 (ligand)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/50Cell markers; Cell surface determinants
    • C12N2501/599Cell markers; Cell surface determinants with CD designations not provided for elsewhere
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2509/00Methods for the dissociation of cells, e.g. specific use of enzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2509/00Methods for the dissociation of cells, e.g. specific use of enzymes
    • C12N2509/10Mechanical dissociation
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701Details
    • G01N2333/4742Keratin; Cytokeratin
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705Assays involving receptors, cell surface antigens or cell surface determinants
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90Enzymes; Proenzymes
    • G01N2333/91Transferases (2.)
    • G01N2333/91045Acyltransferases (2.3)
    • G01N2333/91074Aminoacyltransferases (general) (2.3.2)
    • G01N2333/9108Aminoacyltransferases (general) (2.3.2) with definite EC number (2.3.2.-)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Cell Biology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Virology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pathology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
ES13786132T 2012-10-24 2013-10-24 Poblaciones de células renales y usos de las mismas Active ES2744979T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261718150P 2012-10-24 2012-10-24
US201361876616P 2013-09-11 2013-09-11
PCT/US2013/066707 WO2014066699A1 (en) 2012-10-24 2013-10-24 Renal cell populations and uses thereof

Publications (2)

Publication Number Publication Date
ES2744979T3 ES2744979T3 (es) 2020-02-27
ES2744979T8 true ES2744979T8 (es) 2020-04-28

Family

ID=49517782

Family Applications (2)

Application Number Title Priority Date Filing Date
ES13786132T Active ES2744979T3 (es) 2012-10-24 2013-10-24 Poblaciones de células renales y usos de las mismas
ES19168775T Active ES2876177T3 (es) 2012-10-24 2013-10-24 Poblaciones de células renales y usos de las mismas

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES19168775T Active ES2876177T3 (es) 2012-10-24 2013-10-24 Poblaciones de células renales y usos de las mismas

Country Status (18)

Country Link
US (4) US20150246073A1 (es)
EP (3) EP3901251A1 (es)
JP (2) JP6509119B2 (es)
KR (4) KR102160725B1 (es)
CN (3) CN110184232B (es)
AU (3) AU2013334276B2 (es)
BR (2) BR122020018576B1 (es)
CA (1) CA2889270A1 (es)
DK (2) DK2912165T3 (es)
ES (2) ES2744979T3 (es)
HK (1) HK1215448A1 (es)
HU (2) HUE046176T2 (es)
NZ (2) NZ741724A (es)
PL (2) PL2912165T3 (es)
PT (1) PT2912165T (es)
RU (1) RU2702721C2 (es)
SI (1) SI2912165T1 (es)
WO (1) WO2014066699A1 (es)

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JP2020512406A (ja) * 2017-03-31 2020-04-23 ジェイン,ディーパク 注射用の細胞および足場組成物
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JP7061766B2 (ja) * 2017-09-20 2022-05-02 学校法人同志社 Dj-1タンパク質産生促進用組成物
CN109266616A (zh) * 2018-08-21 2019-01-25 山西省人民医院 一种稳定表达aqp2蛋白的人源化小鼠足细胞模型及其构建方法和应用
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Also Published As

Publication number Publication date
AU2019204178A1 (en) 2019-07-04
RU2019118791A (ru) 2019-07-11
AU2019204178B2 (en) 2021-11-18
SI2912165T1 (sl) 2019-11-29
DK2912165T3 (da) 2019-09-16
US10363274B2 (en) 2019-07-30
KR102215476B1 (ko) 2021-02-17
NZ741724A (en) 2020-02-28
CN104937095A (zh) 2015-09-23
US20150246073A1 (en) 2015-09-03
EP3567099B1 (en) 2021-04-21
EP2912165A1 (en) 2015-09-02
KR20200113287A (ko) 2020-10-06
BR112015009042B1 (pt) 2021-10-19
EP3901251A1 (en) 2021-10-27
WO2014066699A1 (en) 2014-05-01
CN104937095B (zh) 2019-06-07
KR102160725B1 (ko) 2020-09-29
EP2912165B1 (en) 2019-06-19
JP2019141067A (ja) 2019-08-29
EP3567099A1 (en) 2019-11-13
CN110184232B (zh) 2023-10-20
CA2889270A1 (en) 2014-05-01
PL2912165T3 (pl) 2020-01-31
HK1215448A1 (zh) 2016-08-26
AU2013334276B2 (en) 2019-07-04
US20220347221A1 (en) 2022-11-03
NZ707873A (en) 2019-01-25
BR112015009042A8 (pt) 2017-10-10
BR122020018576B1 (pt) 2022-07-05
HUE046176T2 (hu) 2020-02-28
DK3567099T3 (da) 2021-06-07
AU2013334276A1 (en) 2015-05-14
KR20220150419A (ko) 2022-11-10
RU2015119514A (ru) 2016-12-20
ES2744979T3 (es) 2020-02-27
PL3567099T3 (pl) 2021-11-29
ES2876177T3 (es) 2021-11-12
US11369639B2 (en) 2022-06-28
AU2022201010A1 (en) 2022-03-03
RU2702721C2 (ru) 2019-10-09
BR112015009042A2 (pt) 2017-07-04
US20170281684A1 (en) 2017-10-05
JP2016504017A (ja) 2016-02-12
KR102460536B1 (ko) 2022-10-31
CN110184232A (zh) 2019-08-30
CN117660296A (zh) 2024-03-08
JP6509119B2 (ja) 2019-05-08
US20200101112A1 (en) 2020-04-02
KR20210018965A (ko) 2021-02-18
PT2912165T (pt) 2019-09-26
JP6696023B2 (ja) 2020-05-20
HUE054882T2 (hu) 2021-10-28
KR20150085818A (ko) 2015-07-24

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