HUE053863T2 - Penicillin-G acilázok - Google Patents
Penicillin-G acilázokInfo
- Publication number
- HUE053863T2 HUE053863T2 HUE16790135A HUE16790135A HUE053863T2 HU E053863 T2 HUE053863 T2 HU E053863T2 HU E16790135 A HUE16790135 A HU E16790135A HU E16790135 A HUE16790135 A HU E16790135A HU E053863 T2 HUE053863 T2 HU E053863T2
- Authority
- HU
- Hungary
- Prior art keywords
- acylases
- penicillin
- Prior art date
Links
- 108010073038 Penicillin Amidase Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
- C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
- C12N9/84—Penicillin amidase (3.5.1.11)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y305/00—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5)
- C12Y305/01—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5) in linear amides (3.5.1)
- C12Y305/01011—Penicillin amidase (3.5.1.11), i.e. penicillin-amidohydrolase
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Mycology (AREA)
- Diabetes (AREA)
- Biomedical Technology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Endocrinology (AREA)
- Pharmacology & Pharmacy (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- Hematology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562158118P | 2015-05-07 | 2015-05-07 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HUE053863T2 true HUE053863T2 (hu) | 2021-07-28 |
Family
ID=57218075
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HUE16790135A HUE053863T2 (hu) | 2015-05-07 | 2016-05-06 | Penicillin-G acilázok |
Country Status (13)
| Country | Link |
|---|---|
| US (6) | US9944916B2 (https=) |
| EP (1) | EP3292136B1 (https=) |
| JP (1) | JP6755886B2 (https=) |
| KR (1) | KR102604503B1 (https=) |
| CN (1) | CN107531762A (https=) |
| AU (1) | AU2016258091B2 (https=) |
| CA (1) | CA2983620A1 (https=) |
| DK (1) | DK3292136T3 (https=) |
| HU (1) | HUE053863T2 (https=) |
| IL (1) | IL255245B (https=) |
| MX (1) | MX381306B (https=) |
| SG (1) | SG11201708356PA (https=) |
| WO (1) | WO2016179464A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2016258091B2 (en) | 2015-05-07 | 2020-10-01 | Codexis, Inc. | Penicillin-G acylases |
| SG11201808957UA (en) | 2016-05-05 | 2018-11-29 | Codexis Inc | Penicillin-g acylases |
| MX2019008096A (es) | 2017-01-05 | 2019-09-04 | Codexis Inc | Penicilina g acilasas. |
| US11643642B2 (en) | 2017-06-27 | 2023-05-09 | Codexis, Inc. | Penicillin-g acylases |
| KR101985911B1 (ko) * | 2017-12-28 | 2019-06-04 | 아미코젠주식회사 | Achromobacter sp. CCM 4824 유래 페니실린 G 아실라제 변이체 및 이의 이용 |
| CN109207466B (zh) * | 2018-11-08 | 2021-01-08 | 山东鲁抗医药股份有限公司 | 一种青霉素酰化酶的固定化方法及固定化酶 |
| KR102363768B1 (ko) * | 2019-11-15 | 2022-02-16 | 아미코젠주식회사 | 세파졸린 생산성이 증가된 페니실린 g 아실라제 변이체 및 이의 이용 |
Family Cites Families (52)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US603344A (en) | 1898-05-03 | Trough for well-curbs | ||
| CA1338400C (en) | 1983-08-31 | 1996-06-18 | David H. Gelfand | Recombinant fungal cellulases |
| US6869930B1 (en) * | 1993-09-17 | 2005-03-22 | Novo Nordisk A/S | Acylated insulin |
| US6309883B1 (en) | 1994-02-17 | 2001-10-30 | Maxygen, Inc. | Methods and compositions for cellular and metabolic engineering |
| US6335160B1 (en) | 1995-02-17 | 2002-01-01 | Maxygen, Inc. | Methods and compositions for polypeptide engineering |
| US6406855B1 (en) | 1994-02-17 | 2002-06-18 | Maxygen, Inc. | Methods and compositions for polypeptide engineering |
| US5605793A (en) | 1994-02-17 | 1997-02-25 | Affymax Technologies N.V. | Methods for in vitro recombination |
| US6995017B1 (en) | 1994-02-17 | 2006-02-07 | Maxygen, Inc. | Methods for generating polynucleotides having desired characteristics by iterative selection and recombination |
| US6117679A (en) | 1994-02-17 | 2000-09-12 | Maxygen, Inc. | Methods for generating polynucleotides having desired characteristics by iterative selection and recombination |
| US5928905A (en) | 1995-04-18 | 1999-07-27 | Glaxo Group Limited | End-complementary polymerase reaction |
| US20060257890A1 (en) | 1996-05-20 | 2006-11-16 | Maxygen, Inc. | Methods and compositions for cellular and metabolic engineering |
| US5834252A (en) | 1995-04-18 | 1998-11-10 | Glaxo Group Limited | End-complementary polymerase reaction |
| US6165793A (en) | 1996-03-25 | 2000-12-26 | Maxygen, Inc. | Methods for generating polynucleotides having desired characteristics by iterative selection and recombination |
| US5837458A (en) | 1994-02-17 | 1998-11-17 | Maxygen, Inc. | Methods and compositions for cellular and metabolic engineering |
| US6395547B1 (en) | 1994-02-17 | 2002-05-28 | Maxygen, Inc. | Methods for generating polynucleotides having desired characteristics by iterative selection and recombination |
| WO1995033836A1 (en) | 1994-06-03 | 1995-12-14 | Novo Nordisk Biotech, Inc. | Phosphonyldipeptides useful in the treatment of cardiovascular diseases |
| ATE294871T1 (de) | 1994-06-30 | 2005-05-15 | Novozymes Biotech Inc | Nicht-toxisches, nicht-toxigenes, nicht- pathogenes fusarium expressionssystem und darin zu verwendende promotoren und terminatoren |
| AU3346295A (en) | 1994-08-12 | 1996-03-07 | Gist-Brocades B.V. | Mutated penicillin g acylase genes |
| FI104465B (fi) | 1995-06-14 | 2000-02-15 | Valio Oy | Proteiinihydrolysaatteja allergioiden hoitamiseksi tai estämiseksi, niiden valmistus ja käyttö |
| US6506602B1 (en) | 1996-03-25 | 2003-01-14 | Maxygen, Inc. | Methods for generating polynucleotides having desired characteristics by iterative selection and recombination |
| US6096548A (en) | 1996-03-25 | 2000-08-01 | Maxygen, Inc. | Method for directing evolution of a virus |
| EP1717322B1 (en) | 1997-01-17 | 2012-07-18 | Codexis Mayflower Holdings, LLC | Evolution of whole cells and organisms by recursive sequence recombination |
| US6326204B1 (en) | 1997-01-17 | 2001-12-04 | Maxygen, Inc. | Evolution of whole cells and organisms by recursive sequence recombination |
| US7148054B2 (en) | 1997-01-17 | 2006-12-12 | Maxygen, Inc. | Evolution of whole cells and organisms by recursive sequence recombination |
| US6365408B1 (en) | 1998-06-19 | 2002-04-02 | Maxygen, Inc. | Methods of evolving a polynucleotides by mutagenesis and recombination |
| ES2237159T3 (es) | 1998-10-06 | 2005-07-16 | Mark Aaron Emalfarb | Sistema de transformacion en el campo de los hongos micoticos filamentosos en chrysosporium. |
| JP4221100B2 (ja) | 1999-01-13 | 2009-02-12 | エルピーダメモリ株式会社 | 半導体装置 |
| US6436675B1 (en) | 1999-09-28 | 2002-08-20 | Maxygen, Inc. | Use of codon-varied oligonucleotide synthesis for synthetic shuffling |
| US6917882B2 (en) | 1999-01-19 | 2005-07-12 | Maxygen, Inc. | Methods for making character strings, polynucleotides and polypeptides having desired characteristics |
| US6368861B1 (en) | 1999-01-19 | 2002-04-09 | Maxygen, Inc. | Oligonucleotide mediated nucleic acid recombination |
| US6376246B1 (en) | 1999-02-05 | 2002-04-23 | Maxygen, Inc. | Oligonucleotide mediated nucleic acid recombination |
| US7024312B1 (en) | 1999-01-19 | 2006-04-04 | Maxygen, Inc. | Methods for making character strings, polynucleotides and polypeptides having desired characteristics |
| US6961664B2 (en) | 1999-01-19 | 2005-11-01 | Maxygen | Methods of populating data structures for use in evolutionary simulations |
| EP1130093A1 (en) | 1999-01-19 | 2001-09-05 | Maxygen, Inc. | Oligonucleotide mediated nucleic acid recombination |
| US7702464B1 (en) | 2001-08-21 | 2010-04-20 | Maxygen, Inc. | Method and apparatus for codon determining |
| CA2362737A1 (en) | 1999-03-05 | 2000-09-08 | Maxygen, Inc. | Recombination of insertion modified nucleic acids |
| US7430477B2 (en) | 1999-10-12 | 2008-09-30 | Maxygen, Inc. | Methods of populating data structures for use in evolutionary simulations |
| US6519065B1 (en) | 1999-11-05 | 2003-02-11 | Jds Fitel Inc. | Chromatic dispersion compensation device |
| EP1272967A2 (en) | 2000-03-30 | 2003-01-08 | Maxygen, Inc. | In silico cross-over site selection |
| US20050084907A1 (en) | 2002-03-01 | 2005-04-21 | Maxygen, Inc. | Methods, systems, and software for identifying functional biomolecules |
| US7747391B2 (en) | 2002-03-01 | 2010-06-29 | Maxygen, Inc. | Methods, systems, and software for identifying functional biomolecules |
| EP1493027B1 (en) | 2002-03-01 | 2014-10-15 | Codexis Mayflower Holdings, LLC | Methods, systems, and software for identifying functional bio-molecules |
| US7620500B2 (en) | 2002-03-09 | 2009-11-17 | Maxygen, Inc. | Optimization of crossover points for directed evolution |
| DE602004021603D1 (de) * | 2003-07-25 | 2009-07-30 | Conjuchem Biotechnologies Inc | Insulinderivative mit langanhaltender wirkung und verfahren zu deren herstellung |
| EP1654354A1 (en) | 2003-08-11 | 2006-05-10 | Codexis, Inc. | Improved ketoreductase polypeptides and related polynucleotides |
| US8383346B2 (en) | 2008-06-13 | 2013-02-26 | Codexis, Inc. | Combined automated parallel synthesis of polynucleotide variants |
| EP3023494B1 (en) | 2008-06-13 | 2018-11-28 | Codexis, Inc. | Method of synthesizing polynucleotide variants |
| US20090312196A1 (en) | 2008-06-13 | 2009-12-17 | Codexis, Inc. | Method of synthesizing polynucleotide variants |
| WO2010054319A2 (en) * | 2008-11-10 | 2010-05-14 | Codexis, Inc. | Penicillin-g acylases |
| SG171964A1 (en) * | 2008-12-23 | 2011-07-28 | Dsm Ip Assets Bv | Mutant penicillin g acylases |
| CN103074320B (zh) * | 2012-05-25 | 2018-06-08 | 石药集团中奇制药技术（石家庄）有限公司 | 含有一个或几个点突变的青霉素g酰化酶 |
| AU2016258091B2 (en) | 2015-05-07 | 2020-10-01 | Codexis, Inc. | Penicillin-G acylases |
-
2016
- 2016-05-06 AU AU2016258091A patent/AU2016258091B2/en active Active
- 2016-05-06 MX MX2017014213A patent/MX381306B/es unknown
- 2016-05-06 HU HUE16790135A patent/HUE053863T2/hu unknown
- 2016-05-06 CA CA2983620A patent/CA2983620A1/en active Pending
- 2016-05-06 WO PCT/US2016/031132 patent/WO2016179464A1/en not_active Ceased
- 2016-05-06 CN CN201680026529.8A patent/CN107531762A/zh active Pending
- 2016-05-06 EP EP16790135.4A patent/EP3292136B1/en active Active
- 2016-05-06 KR KR1020177033631A patent/KR102604503B1/ko active Active
- 2016-05-06 US US15/148,056 patent/US9944916B2/en active Active
- 2016-05-06 SG SG11201708356PA patent/SG11201708356PA/en unknown
- 2016-05-06 DK DK16790135.4T patent/DK3292136T3/da active
- 2016-05-06 JP JP2017557457A patent/JP6755886B2/ja active Active
-
2017
- 2017-10-24 IL IL255245A patent/IL255245B/en active IP Right Grant
-
2018
- 2018-03-07 US US15/914,258 patent/US10400231B2/en active Active
-
2019
- 2019-07-29 US US16/524,546 patent/US10781436B2/en active Active
-
2020
- 2020-08-17 US US16/995,630 patent/US11180747B2/en active Active
-
2021
- 2021-10-19 US US17/504,852 patent/US12378541B2/en active Active
-
2025
- 2025-07-22 US US19/276,625 patent/US20250346882A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US12378541B2 (en) | 2025-08-05 |
| US9944916B2 (en) | 2018-04-17 |
| IL255245A0 (en) | 2017-12-31 |
| SG11201708356PA (en) | 2017-11-29 |
| AU2016258091B2 (en) | 2020-10-01 |
| MX2017014213A (es) | 2018-03-28 |
| US20160326508A1 (en) | 2016-11-10 |
| CN107531762A (zh) | 2018-01-02 |
| JP2018515089A (ja) | 2018-06-14 |
| KR102604503B1 (ko) | 2023-11-20 |
| EP3292136A4 (en) | 2019-04-10 |
| NZ736220A (en) | 2024-03-22 |
| US10781436B2 (en) | 2020-09-22 |
| DK3292136T3 (da) | 2021-03-22 |
| US20190345474A1 (en) | 2019-11-14 |
| US20180201919A1 (en) | 2018-07-19 |
| IL255245B (en) | 2020-03-31 |
| US11180747B2 (en) | 2021-11-23 |
| AU2016258091A1 (en) | 2017-11-02 |
| EP3292136B1 (en) | 2021-02-17 |
| EP3292136A1 (en) | 2018-03-14 |
| US20200385699A1 (en) | 2020-12-10 |
| WO2016179464A1 (en) | 2016-11-10 |
| US20250346882A1 (en) | 2025-11-13 |
| JP6755886B2 (ja) | 2020-09-16 |
| KR20180004169A (ko) | 2018-01-10 |
| US20220042004A1 (en) | 2022-02-10 |
| MX381306B (es) | 2025-03-12 |
| CA2983620A1 (en) | 2016-11-10 |
| US10400231B2 (en) | 2019-09-03 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NL301301I2 (nl) | ciltacabtagene autoleucel | |
| EP3374114A4 (en) | WORKBENCH | |
| PL3417725T3 (pl) | Fajka wodna | |
| DK3283625T3 (da) | Nukleasemedieret genomeditering | |
| EP3286361A4 (en) | Cancer neoepitopes | |
| DK3331869T3 (da) | Muscarinagonister | |
| DK3331528T3 (da) | Muskarinagonister | |
| DK3277719T3 (da) | Polypeptider | |
| EP3316375A4 (en) | Redox flow cell | |
| DK3360890T3 (da) | Genterapi | |
| DK3305788T3 (da) | Janus-kinase-hæmmer | |
| DK3331529T3 (da) | Muskarinagonister | |
| EP3290364A4 (en) | Conveyor belt wear monitoring system | |
| DK3310450T3 (da) | Olie-vand-separator | |
| DK3270930T3 (da) | Præeklampsi | |
| DK3394281T3 (da) | Gærcelle | |
| HUE053863T2 (hu) | Penicillin-G acilázok | |
| EP3363322A4 (en) | Hair extender | |
| IL271505A (en) | Penicillin-G Acylases | |
| DK3274482T3 (da) | Stenborsknop | |
| EP3552872A4 (en) | SUSPENSION | |
| DE112015006486A5 (de) | Inkubationsrinne | |
| DE102015206660A8 (de) | Plattenaufteilanlage | |
| EP3308871A4 (en) | CRIMPING DEVICE | |
| DE112015005904A5 (de) | Gurtschlossbringer |