HUE045310T2 - Eljárás G-CSF elõállítására - Google Patents

Eljárás G-CSF elõállítására

Info

Publication number
HUE045310T2
HUE045310T2 HUE13709469A HUE13709469A HUE045310T2 HU E045310 T2 HUE045310 T2 HU E045310T2 HU E13709469 A HUE13709469 A HU E13709469A HU E13709469 A HUE13709469 A HU E13709469A HU E045310 T2 HUE045310 T2 HU E045310T2
Authority
HU
Hungary
Prior art keywords
csf
production
Prior art date
Application number
HUE13709469A
Other languages
English (en)
Inventor
Ferenc Felfoeldi
Katalin Olasz
Jozsef Kozma
Original Assignee
Richter Gedeon Nyrt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Nyrt filed Critical Richter Gedeon Nyrt
Publication of HUE045310T2 publication Critical patent/HUE045310T2/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/53—Colony-stimulating factor [CSF]
    • C07K14/535—Granulocyte CSF; Granulocyte-macrophage CSF
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
HUE13709469A 2012-03-19 2013-03-18 Eljárás G-CSF elõállítására HUE045310T2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU1200171A HUP1200171A1 (hu) 2012-03-19 2012-03-19 Módszerek polipeptidek elõállítására

Publications (1)

Publication Number Publication Date
HUE045310T2 true HUE045310T2 (hu) 2019-12-30

Family

ID=89990648

Family Applications (2)

Application Number Title Priority Date Filing Date
HU1200171A HUP1200171A1 (hu) 2012-03-19 2012-03-19 Módszerek polipeptidek elõállítására
HUE13709469A HUE045310T2 (hu) 2012-03-19 2013-03-18 Eljárás G-CSF elõállítására

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HU1200171A HUP1200171A1 (hu) 2012-03-19 2012-03-19 Módszerek polipeptidek elõállítására

Country Status (15)

Country Link
US (1) US9416164B2 (hu)
EP (2) EP2828396B1 (hu)
JP (1) JP6154885B2 (hu)
KR (1) KR101949556B1 (hu)
CN (1) CN104603280A (hu)
CA (1) CA2867794C (hu)
DK (1) DK2828396T3 (hu)
ES (1) ES2732374T3 (hu)
HR (1) HRP20190846T1 (hu)
HU (2) HUP1200171A1 (hu)
LT (1) LT2828396T (hu)
PL (1) PL2828396T3 (hu)
SI (1) SI2828396T1 (hu)
TR (1) TR201907221T4 (hu)
WO (1) WO2013068602A2 (hu)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUP1200172A2 (en) 2012-03-19 2013-10-28 Richter Gedeon Nyrt Methods for refolding g-csf from inclusion bodies
HUP1200171A1 (hu) 2012-03-19 2013-09-30 Richter Gedeon Nyrt Módszerek polipeptidek elõállítására
US10435732B2 (en) 2014-06-09 2019-10-08 Kaneka Corporation Method for producing recombinant proteins using recombinant brevibacillus
EP3902820A2 (en) * 2018-12-28 2021-11-03 Coherus Biosciences, Inc. Process for producing, isolating, and purifying modified recombinant proteins
WO2020234742A1 (en) * 2019-05-20 2020-11-26 Lupin Limited Granulocyte colony stimulating factor purification

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61227526A (ja) 1984-07-25 1986-10-09 Chugai Pharmaceut Co Ltd 新規なコロニー刺激因子
US4810643A (en) 1985-08-23 1989-03-07 Kirin- Amgen Inc. Production of pluripotent granulocyte colony-stimulating factor
DE3537708A1 (de) 1985-10-23 1987-04-23 Boehringer Mannheim Gmbh Verfahren zur aktivierung von t-pa nach expression in prokaryonten
JPH0618780B2 (ja) * 1986-01-22 1994-03-16 中外製薬株式会社 骨髄性白血病抑制剤
US5714581A (en) 1986-12-23 1998-02-03 Kyowa Hakko Kogyo Co., Ltd. Polypeptide derivatives of human granulocyte colony stimulating factor
KR0133561B1 (ko) 1988-05-13 1998-04-21 스티븐 엠. 오드레 과립구 군체 자극인자의 정제방법
DE3835350A1 (de) 1988-10-17 1990-04-19 Boehringer Mannheim Gmbh Aktivierung von gentechnologisch hergestellten, in prokaryonten exprimierten antikoerpern
EP0401384B1 (en) 1988-12-22 1996-03-13 Kirin-Amgen, Inc. Chemically modified granulocyte colony stimulating factor
US5055555A (en) 1989-01-05 1991-10-08 Helmut Sassenfeld Purification of G-CSF
FR2669646A1 (fr) 1990-11-23 1992-05-29 Lorraine Laminage Procede de traitement d'un effluent aqueux issu d'un procede d'electrozingage, ainsi que procede et installation en comportant application.
DE4114575C1 (hu) 1991-05-04 1992-05-14 Fa. Carl Freudenberg, 6940 Weinheim, De
KR100241257B1 (ko) 1997-05-22 2000-02-01 한승수 인체 과립구 콜로니 자극 인자 활성물질 및 그것의 제조방법
EP1095056B1 (en) 1998-07-09 2006-12-27 BaroFold, Inc. High pressure refolding of protein aggregates and inclusion bodies
FR2796071B1 (fr) 1999-07-08 2001-09-07 Hoechst Marion Roussel Inc Procede de purification de facteur de stimulation de colonies de granulocytes
EP1284987B1 (en) 2000-05-16 2007-07-18 Bolder Biotechnology, Inc. Methods for refolding proteins containing free cysteine residues
SI21102A (sl) 2001-12-19 2003-06-30 LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. Postopek za izolacijo biološko aktivnega granulocitne kolonije stimulirajočega dejavnika
AU2002345829A1 (en) 2002-06-24 2004-01-06 Dr. Reddy's Laboratories Ltd. Process for preparing g-csf
SI21273A (sl) 2002-07-31 2004-02-29 LEK farmacevtska dru�ba d.d. Priprava inkluzijskih teles z visokim deležem pravilno zvitega prekurzorja heterolognega proteina
KR100484653B1 (ko) * 2004-05-06 2005-04-20 주식회사 대웅 원핵세포에서 활성형의 가용성 단백질을 제조하는 방법 및 이를 위한 폴리시스트론 벡터
DE102004041639A1 (de) 2004-08-27 2006-03-02 Bioceuticals Arzneimittel Ag Verfahren zur Gewinnung von biologisch aktivem humanen G-CSF aus Inclusion Bodies
US20080171857A1 (en) 2005-03-17 2008-07-17 Uma Devi Komath Process for the Purification of Recombinant Granulocyte-Colony Stimulating Factor
KR100694994B1 (ko) 2005-06-13 2007-03-14 씨제이 주식회사 사람 과립구 콜로니 형성인자 동종체
GB0605684D0 (en) 2006-03-21 2006-05-03 Sicor Biotech Uab Method For Purifying Granulocyte-Colony Stimulating Factor
EP1977314A1 (en) 2006-07-21 2008-10-08 Sony Service Centre (Europe) N.V. Demodulator device and method of operating the same
WO2008096368A2 (en) 2007-02-05 2008-08-14 Natco Pharma Limited A novel process for production of recombinant human g-csf
WO2008096370A2 (en) 2007-02-05 2008-08-14 Natco Pharma Limited An efficient and novel purification method of recombinant hg-csf
CN101358196A (zh) 2008-08-29 2009-02-04 浙江理工大学 利用家蚕后部丝腺体外表达系统合成蛋白质的方法
CN101691560B (zh) 2008-12-19 2011-08-31 华南理工大学 大肠杆菌及其可溶性表达转谷氨酰胺酶酶原的方法
US20120093765A1 (en) 2009-06-16 2012-04-19 Lupin Limited Process for purification of recombinant human granulocyte colony stimulating factor
HUP1200171A1 (hu) 2012-03-19 2013-09-30 Richter Gedeon Nyrt Módszerek polipeptidek elõállítására
HUP1200172A2 (en) 2012-03-19 2013-10-28 Richter Gedeon Nyrt Methods for refolding g-csf from inclusion bodies

Also Published As

Publication number Publication date
JP6154885B2 (ja) 2017-06-28
HRP20190846T1 (hr) 2019-08-09
US20150044721A1 (en) 2015-02-12
CA2867794C (en) 2020-06-09
DK2828396T3 (da) 2019-05-27
WO2013068602A3 (en) 2013-08-01
US9416164B2 (en) 2016-08-16
KR101949556B1 (ko) 2019-02-18
SI2828396T1 (sl) 2019-06-28
EP3517621A1 (en) 2019-07-31
CA2867794A1 (en) 2013-05-16
EP2828396A2 (en) 2015-01-28
HUP1200171A1 (hu) 2013-09-30
ES2732374T3 (es) 2019-11-22
PL2828396T3 (pl) 2019-08-30
EP2828396B1 (en) 2019-04-24
KR20140144705A (ko) 2014-12-19
JP2015514398A (ja) 2015-05-21
WO2013068602A2 (en) 2013-05-16
LT2828396T (lt) 2019-05-27
CN104603280A (zh) 2015-05-06
TR201907221T4 (tr) 2019-06-21

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