HUE040503T2 - Kezelési eljárások ammónia-leválasztó gyógyszerek használatával - Google Patents

Kezelési eljárások ammónia-leválasztó gyógyszerek használatával

Info

Publication number
HUE040503T2
HUE040503T2 HUE16176456A HUE16176456A HUE040503T2 HU E040503 T2 HUE040503 T2 HU E040503T2 HU E16176456 A HUE16176456 A HU E16176456A HU E16176456 A HUE16176456 A HU E16176456A HU E040503 T2 HUE040503 T2 HU E040503T2
Authority
HU
Hungary
Prior art keywords
ammonia
treatment
methods
scavenging drugs
scavenging
Prior art date
Application number
HUE16176456A
Other languages
English (en)
Inventor
Bruce Scharschmidt
Original Assignee
Horizon Therapeutics Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Horizon Therapeutics Llc filed Critical Horizon Therapeutics Llc
Publication of HUE040503T2 publication Critical patent/HUE040503T2/hu

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6806Determination of free amino acids
    • G01N33/6812Assays for specific amino acids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/08Hepato-biliairy disorders other than hepatitis
    • G01N2800/085Liver diseases, e.g. portal hypertension, fibrosis, cirrhosis, bilirubin
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/34Genitourinary disorders
    • G01N2800/347Renal failures; Glomerular diseases; Tubulointerstitial diseases, e.g. nephritic syndrome, glomerulonephritis; Renovascular diseases, e.g. renal artery occlusion, nephropathy
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/52Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Food Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
HUE16176456A 2008-08-29 2009-01-07 Kezelési eljárások ammónia-leválasztó gyógyszerek használatával HUE040503T2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US9323408P 2008-08-29 2008-08-29

Publications (1)

Publication Number Publication Date
HUE040503T2 true HUE040503T2 (hu) 2019-03-28

Family

ID=45604478

Family Applications (2)

Application Number Title Priority Date Filing Date
HUE09739263A HUE029912T2 (hu) 2008-08-29 2009-01-07 Kezelési eljárások ammónia-megkötõ hatóanyag alkalmazásával
HUE16176456A HUE040503T2 (hu) 2008-08-29 2009-01-07 Kezelési eljárások ammónia-leválasztó gyógyszerek használatával

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HUE09739263A HUE029912T2 (hu) 2008-08-29 2009-01-07 Kezelési eljárások ammónia-megkötõ hatóanyag alkalmazásával

Country Status (10)

Country Link
JP (3) JP5577341B2 (hu)
DK (1) DK3133396T3 (hu)
ES (2) ES2593378T3 (hu)
HR (2) HRP20161222T1 (hu)
HU (2) HUE029912T2 (hu)
LT (2) LT3133396T (hu)
PL (1) PL2330892T3 (hu)
PT (2) PT2330892T (hu)
SI (1) SI3133396T1 (hu)
TR (1) TR201816616T4 (hu)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX366197B (es) 2011-09-30 2019-06-25 Horizon Therapeutics Llc Metodo de monitoreo terapeutico de farmacos depuradores de nitrogeno.
BR112014026138A2 (pt) * 2012-04-20 2017-06-27 Hyperion Therapeutics Inc métodos de monitoramento terapêutico de pró-fármacos de ácido fenilacético
RS56757B1 (sr) * 2012-11-21 2018-04-30 Horizon Therapeutics Llc Postupci davanja i procene lekova za uklanjanje azota za lečenje hepatične encefalopatije
US9914692B2 (en) 2016-05-25 2018-03-13 Horizon Therapeutics, Llc Procedure for the preparation of 4-phenyl butyrate and uses thereof
US10668040B2 (en) 2017-09-11 2020-06-02 Horizon Therapeutics, Llc Treatment of urea cycle disorders in neonates and infants
US20220044801A1 (en) * 2018-10-04 2022-02-10 Atonarp Inc. Living body information acquisition system, health management server, and system

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4284647A (en) * 1980-03-31 1981-08-18 The Johns Hopkins University Process for waste nitrogen removal
DE69612755T2 (de) * 1995-02-07 2001-08-23 Brusilow Entpr Llc Triglyceride und ethylester von phenylalkansäuren und phenylalkensäuren zur behandlung verschiedener erkrankungen
US20070004805A1 (en) * 2005-07-01 2007-01-04 Navinta Llc Process for preparation of liquid dosage form containing sodium 4-phenylbutyrate

Also Published As

Publication number Publication date
SI3133396T1 (sl) 2018-12-31
LT3133396T (lt) 2018-11-26
PL2330892T3 (pl) 2017-05-31
HRP20181877T1 (hr) 2019-01-11
ES2593378T3 (es) 2016-12-09
HUE029912T2 (hu) 2017-03-28
JP2014102255A (ja) 2014-06-05
PT3133396T (pt) 2018-12-07
DK3133396T3 (en) 2018-12-03
LT2330892T (lt) 2016-11-25
TR201816616T4 (tr) 2018-11-21
JP5577341B2 (ja) 2014-08-20
HRP20161222T1 (hr) 2017-02-10
PT2330892T (pt) 2016-09-05
JP2012501329A (ja) 2012-01-19
JP2012501451A (ja) 2012-01-19
ES2695534T3 (es) 2019-01-08

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