HRP20181877T1 - Postupci za liječenje lijekovima koji uklanjaju amonijak - Google Patents

Postupci za liječenje lijekovima koji uklanjaju amonijak

Info

Publication number
HRP20181877T1
HRP20181877T1 HRP20181877TT HRP20181877T HRP20181877T1 HR P20181877 T1 HRP20181877 T1 HR P20181877T1 HR P20181877T T HRP20181877T T HR P20181877TT HR P20181877 T HRP20181877 T HR P20181877T HR P20181877 T1 HRP20181877 T1 HR P20181877T1
Authority
HR
Croatia
Prior art keywords
ammonia
treatment
methods
scavenging drugs
scavenging
Prior art date
Application number
HRP20181877TT
Other languages
English (en)
Inventor
Bruce Scharschmidt
Original Assignee
Horizon Therapeutics, Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP16176456.8A external-priority patent/EP3133396B1/en
Application filed by Horizon Therapeutics, Llc filed Critical Horizon Therapeutics, Llc
Publication of HRP20181877T1 publication Critical patent/HRP20181877T1/hr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6806—Determination of free amino acids
    • G01N33/6812—Assays for specific amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/08—Hepato-biliairy disorders other than hepatitis
    • G01N2800/085—Liver diseases, e.g. portal hypertension, fibrosis, cirrhosis, bilirubin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/34—Genitourinary disorders
    • G01N2800/347—Renal failures; Glomerular diseases; Tubulointerstitial diseases, e.g. nephritic syndrome, glomerulonephritis; Renovascular diseases, e.g. renal artery occlusion, nephropathy
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
HRP20181877TT 2008-08-29 2018-11-08 Postupci za liječenje lijekovima koji uklanjaju amonijak HRP20181877T1 (hr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US9323408P 2008-08-29 2008-08-29
EP16176456.8A EP3133396B1 (en) 2008-04-29 2009-01-07 Methods of treatment using ammonia-scavenging drugs

Publications (1)

Publication Number Publication Date
HRP20181877T1 true HRP20181877T1 (hr) 2019-01-11

Family

ID=45604478

Family Applications (2)

Application Number Title Priority Date Filing Date
HRP20161222TT HRP20161222T1 (hr) 2008-08-29 2016-09-26 Postupci liječenja koristeći lijekove za izbacivanje amonijaka
HRP20181877TT HRP20181877T1 (hr) 2008-08-29 2018-11-08 Postupci za liječenje lijekovima koji uklanjaju amonijak

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HRP20161222TT HRP20161222T1 (hr) 2008-08-29 2016-09-26 Postupci liječenja koristeći lijekove za izbacivanje amonijaka

Country Status (10)

Country Link
JP (3) JP5577341B2 (hr)
DK (1) DK3133396T3 (hr)
ES (2) ES2695534T3 (hr)
HR (2) HRP20161222T1 (hr)
HU (2) HUE040503T2 (hr)
LT (2) LT3133396T (hr)
PL (1) PL2330892T3 (hr)
PT (2) PT3133396T (hr)
SI (1) SI3133396T1 (hr)
TR (1) TR201816616T4 (hr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20140094517A (ko) 2011-09-30 2014-07-30 하이페리온 쎄라퓨틱스, 인크. 질소 스캐빈징 약물들의 치료학적 모니터링 방법들
DK2846791T3 (en) * 2012-04-20 2017-03-27 Horizon Therapeutics Llc HPN-100 FOR USE IN TREATMENT OF NITROGEN RETENTION DISORDER
US9289406B2 (en) * 2012-11-21 2016-03-22 Horizon Therapeutics, Inc. Methods of administering and evaluating nitrogen scavenging drugs for the treatment of hepatic encephalopathy
US9914692B2 (en) 2016-05-25 2018-03-13 Horizon Therapeutics, Llc Procedure for the preparation of 4-phenyl butyrate and uses thereof
US10668040B2 (en) 2017-09-11 2020-06-02 Horizon Therapeutics, Llc Treatment of urea cycle disorders in neonates and infants
JP6797456B2 (ja) * 2018-10-04 2020-12-09 アトナープ株式会社 生体情報取得システム、健康管理サーバーおよびシステム

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4284647A (en) * 1980-03-31 1981-08-18 The Johns Hopkins University Process for waste nitrogen removal
DE69612755T2 (de) * 1995-02-07 2001-08-23 Brusilow Entpr Llc Triglyceride und ethylester von phenylalkansäuren und phenylalkensäuren zur behandlung verschiedener erkrankungen
US20070004805A1 (en) * 2005-07-01 2007-01-04 Navinta Llc Process for preparation of liquid dosage form containing sodium 4-phenylbutyrate

Also Published As

Publication number Publication date
LT3133396T (lt) 2018-11-26
SI3133396T1 (sl) 2018-12-31
PL2330892T3 (pl) 2017-05-31
DK3133396T3 (en) 2018-12-03
PT3133396T (pt) 2018-12-07
JP2012501451A (ja) 2012-01-19
JP2012501329A (ja) 2012-01-19
ES2593378T3 (es) 2016-12-09
TR201816616T4 (tr) 2018-11-21
JP5577341B2 (ja) 2014-08-20
HUE029912T2 (en) 2017-03-28
HUE040503T2 (hu) 2019-03-28
ES2695534T3 (es) 2019-01-08
LT2330892T (lt) 2016-11-25
HRP20161222T1 (hr) 2017-02-10
PT2330892T (pt) 2016-09-05
JP2014102255A (ja) 2014-06-05

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