LT3133396T - Gydymo būdai, panaudojant amoniaką deaktyvuojančius vaistus - Google Patents

Gydymo būdai, panaudojant amoniaką deaktyvuojančius vaistus

Info

Publication number
LT3133396T
LT3133396T LTEP16176456.8T LT16176456T LT3133396T LT 3133396 T LT3133396 T LT 3133396T LT 16176456 T LT16176456 T LT 16176456T LT 3133396 T LT3133396 T LT 3133396T
Authority
LT
Lithuania
Prior art keywords
ammonia
treatment
methods
scavenging drugs
scavenging
Prior art date
Application number
LTEP16176456.8T
Other languages
English (en)
Lithuanian (lt)
Inventor
Bruce Scharschmidt
Original Assignee
Horizon Therapeutics, Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Horizon Therapeutics, Llc filed Critical Horizon Therapeutics, Llc
Publication of LT3133396T publication Critical patent/LT3133396T/lt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6806Determination of free amino acids
    • G01N33/6812Assays for specific amino acids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/08Hepato-biliairy disorders other than hepatitis
    • G01N2800/085Liver diseases, e.g. portal hypertension, fibrosis, cirrhosis, bilirubin
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/34Genitourinary disorders
    • G01N2800/347Renal failures; Glomerular diseases; Tubulointerstitial diseases, e.g. nephritic syndrome, glomerulonephritis; Renovascular diseases, e.g. renal artery occlusion, nephropathy
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/52Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
LTEP16176456.8T 2008-08-29 2009-01-07 Gydymo būdai, panaudojant amoniaką deaktyvuojančius vaistus LT3133396T (lt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US9323408P 2008-08-29 2008-08-29

Publications (1)

Publication Number Publication Date
LT3133396T true LT3133396T (lt) 2018-11-26

Family

ID=45604478

Family Applications (2)

Application Number Title Priority Date Filing Date
LTEP09739263.3T LT2330892T (lt) 2008-08-29 2009-01-07 Gydymo būdai panaudojant vaistus - amoniako gaudykles
LTEP16176456.8T LT3133396T (lt) 2008-08-29 2009-01-07 Gydymo būdai, panaudojant amoniaką deaktyvuojančius vaistus

Family Applications Before (1)

Application Number Title Priority Date Filing Date
LTEP09739263.3T LT2330892T (lt) 2008-08-29 2009-01-07 Gydymo būdai panaudojant vaistus - amoniako gaudykles

Country Status (10)

Country Link
JP (3) JP5577341B2 (hr)
DK (1) DK3133396T3 (hr)
ES (2) ES2695534T3 (hr)
HR (2) HRP20161222T1 (hr)
HU (2) HUE029912T2 (hr)
LT (2) LT2330892T (hr)
PL (1) PL2330892T3 (hr)
PT (2) PT2330892T (hr)
SI (1) SI3133396T1 (hr)
TR (1) TR201816616T4 (hr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2760479T3 (en) 2011-09-30 2017-07-17 Horizon Therapeutics Llc Nitrogen-removing drug for use in a method of treating a nitrogen retention disorder
CN113995743A (zh) * 2012-04-20 2022-02-01 伊梅尔迪卡制药公司 苯乙酸前药的治疗性监测方法
US9289406B2 (en) * 2012-11-21 2016-03-22 Horizon Therapeutics, Inc. Methods of administering and evaluating nitrogen scavenging drugs for the treatment of hepatic encephalopathy
US9914692B2 (en) 2016-05-25 2018-03-13 Horizon Therapeutics, Llc Procedure for the preparation of 4-phenyl butyrate and uses thereof
US10668040B2 (en) 2017-09-11 2020-06-02 Horizon Therapeutics, Llc Treatment of urea cycle disorders in neonates and infants
JP6797456B2 (ja) * 2018-10-04 2020-12-09 アトナープ株式会社 生体情報取得システム、健康管理サーバーおよびシステム

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4284647A (en) * 1980-03-31 1981-08-18 The Johns Hopkins University Process for waste nitrogen removal
ES2157422T3 (es) * 1995-02-07 2001-08-16 Brusilow Entpr Llc Trigliceridos y esteres etilicos de acido fenilalcanoico y acido fenilalquenoico utiles en el tratamiento de diversos trastornos.
US20070004805A1 (en) * 2005-07-01 2007-01-04 Navinta Llc Process for preparation of liquid dosage form containing sodium 4-phenylbutyrate

Also Published As

Publication number Publication date
LT2330892T (lt) 2016-11-25
ES2695534T3 (es) 2019-01-08
HUE029912T2 (en) 2017-03-28
JP5577341B2 (ja) 2014-08-20
PL2330892T3 (pl) 2017-05-31
JP2012501329A (ja) 2012-01-19
JP2014102255A (ja) 2014-06-05
ES2593378T3 (es) 2016-12-09
HRP20161222T1 (hr) 2017-02-10
DK3133396T3 (en) 2018-12-03
HRP20181877T1 (hr) 2019-01-11
HUE040503T2 (hu) 2019-03-28
PT3133396T (pt) 2018-12-07
JP2012501451A (ja) 2012-01-19
SI3133396T1 (sl) 2018-12-31
PT2330892T (pt) 2016-09-05
TR201816616T4 (tr) 2018-11-21

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