HUE039290T2 - Új alfa2 adrenoceptor-agonisták - Google Patents
Új alfa2 adrenoceptor-agonistákInfo
- Publication number
- HUE039290T2 HUE039290T2 HUE13719297A HUE13719297A HUE039290T2 HU E039290 T2 HUE039290 T2 HU E039290T2 HU E13719297 A HUE13719297 A HU E13719297A HU E13719297 A HUE13719297 A HU E13719297A HU E039290 T2 HUE039290 T2 HU E039290T2
- Authority
- HU
- Hungary
- Prior art keywords
- new
- adrenoceptor agonists
- alpha2 adrenoceptor
- alpha2
- agonists
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A61P25/10—Antiepileptics; Anticonvulsants for petit-mal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A61P25/12—Antiepileptics; Anticonvulsants for grand-mal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Addiction (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Epidemiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Psychology (AREA)
- Rheumatology (AREA)
- Hospice & Palliative Care (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Anesthesiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261619109P | 2012-04-02 | 2012-04-02 |
Publications (1)
Publication Number | Publication Date |
---|---|
HUE039290T2 true HUE039290T2 (hu) | 2018-12-28 |
Family
ID=48224812
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HUE13719297A HUE039290T2 (hu) | 2012-04-02 | 2013-03-28 | Új alfa2 adrenoceptor-agonisták |
HUS2200005C HUS2200005I1 (hu) | 2012-04-02 | 2022-02-02 | Új alfa2 adrenoceptor-agonisták |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HUS2200005C HUS2200005I1 (hu) | 2012-04-02 | 2022-02-02 | Új alfa2 adrenoceptor-agonisták |
Country Status (26)
Country | Link |
---|---|
US (1) | US9249127B2 (hu) |
EP (1) | EP2834233B1 (hu) |
JP (1) | JP6427096B2 (hu) |
KR (1) | KR102104228B1 (hu) |
CN (1) | CN104220437B (hu) |
AR (1) | AR090557A1 (hu) |
AU (1) | AU2013244859B2 (hu) |
BR (1) | BR112014023957B1 (hu) |
CA (1) | CA2868611C (hu) |
DK (1) | DK2834233T3 (hu) |
ES (1) | ES2674945T3 (hu) |
FR (1) | FR22C1005I1 (hu) |
HK (1) | HK1205115A1 (hu) |
HR (1) | HRP20181203T1 (hu) |
HU (2) | HUE039290T2 (hu) |
IL (1) | IL234663B (hu) |
LT (2) | LT2834233T (hu) |
MX (1) | MX358429B (hu) |
NL (1) | NL301160I2 (hu) |
NO (1) | NO2022002I1 (hu) |
PL (1) | PL2834233T3 (hu) |
PT (1) | PT2834233T (hu) |
RU (1) | RU2642065C2 (hu) |
SI (1) | SI2834233T1 (hu) |
TW (1) | TWI620746B (hu) |
WO (1) | WO2013150173A1 (hu) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPWO2015152196A1 (ja) * | 2014-03-31 | 2017-04-13 | 東レ株式会社 | イミダゾリン誘導体及びその医薬用途 |
EP3256466B9 (en) * | 2015-02-11 | 2022-07-27 | Sunovion Pharmaceuticals Inc. | 1-heterocyclyl isochromanyl compounds and analogs for treating cns disorders |
CN105646306B (zh) * | 2015-12-11 | 2020-06-30 | 广东莱佛士制药技术有限公司 | 一种4-甲硫基苯乙酸的制备方法 |
SI3717476T1 (sl) | 2017-12-01 | 2022-10-28 | Orion Corporation | Postopek priprave 2-(5-metoksiizokroman-1-il)-4,5-dihidro-1H-imidazola in njegove hidrogensulfatne soli |
CN110272407B (zh) * | 2019-07-22 | 2021-02-05 | 河北省农林科学院经济作物研究所 | 一种用于降血压的天然异色满酮类化合物 |
CN117157070A (zh) | 2021-03-19 | 2023-12-01 | 奥赖恩公司 | 他西匹啶(tasipimidine)制剂及其用途 |
WO2023139313A1 (en) | 2022-01-24 | 2023-07-27 | Orion Corporation | Novel sulfate salt forms of isochroman-imidazole structured alpha-2a adrenoceptor agonist |
WO2023148431A1 (en) | 2022-02-04 | 2023-08-10 | Orion Corporation | Novel salt forms of isochroman-imidazole structured alpha-2a adrenoceptor agonist |
WO2024069050A1 (en) | 2022-09-28 | 2024-04-04 | Orion Corporation | Tasipimidine and cyp2d6 inhibitor combination treatment |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1247008B (de) * | 1965-10-05 | 1967-08-10 | Huels Chemische Werke Ag | Thermoplastische Massen zur Herstellung von vergilbungsfreien antielektrostatischen Formkoerpern aus Polyolefinen |
US3438995A (en) * | 1968-01-08 | 1969-04-15 | Melville Sahyun | Diazaheterocyclic substituted benz-oxaheterocyclic compounds |
DE3583900D1 (de) * | 1984-06-06 | 1991-10-02 | Abbott Lab | Adrenergische verbindungen. |
EP1413576A3 (en) * | 1997-12-04 | 2004-09-01 | Allergan, Inc. | Substituted imidazole derivatives having agonist-like activity at alpha 2B or 2B/2C adrenergic receptors |
FI20000073A0 (fi) * | 2000-01-14 | 2000-01-14 | Orion Yhtymae Oy | Uusia imidatsolijohdannaisia |
AU2007209382A1 (en) | 2006-01-27 | 2007-08-02 | F. Hoffmann-La Roche Ag | Use of 2-imidazoles for the treatment of CNS disorders |
JP2009524616A (ja) | 2006-01-27 | 2009-07-02 | エフ.ホフマン−ラ ロシュ アーゲー | Cns疾患のための4−イミダゾール誘導体の使用 |
US20080020076A1 (en) * | 2006-07-21 | 2008-01-24 | Khem Jhamandas | Methods and Therapies for Potentiating a Therapeutic Action of an Alpha-2 Adrenergic Receptor Agonist and Inhibiting and/or Reversing Tolerance to Alpha-2 Adrenergic Receptor Agonists |
-
2013
- 2013-03-27 AR ARP130101043 patent/AR090557A1/es active IP Right Grant
- 2013-03-28 EP EP13719297.7A patent/EP2834233B1/en active Active
- 2013-03-28 ES ES13719297.7T patent/ES2674945T3/es active Active
- 2013-03-28 WO PCT/FI2013/000013 patent/WO2013150173A1/en active Application Filing
- 2013-03-28 AU AU2013244859A patent/AU2013244859B2/en active Active
- 2013-03-28 BR BR112014023957-6A patent/BR112014023957B1/pt active IP Right Grant
- 2013-03-28 PT PT137192977T patent/PT2834233T/pt unknown
- 2013-03-28 PL PL13719297T patent/PL2834233T3/pl unknown
- 2013-03-28 CN CN201380018776.XA patent/CN104220437B/zh active Active
- 2013-03-28 CA CA2868611A patent/CA2868611C/en active Active
- 2013-03-28 JP JP2015503903A patent/JP6427096B2/ja active Active
- 2013-03-28 KR KR1020147027610A patent/KR102104228B1/ko active IP Right Grant
- 2013-03-28 HU HUE13719297A patent/HUE039290T2/hu unknown
- 2013-03-28 SI SI201331024T patent/SI2834233T1/en unknown
- 2013-03-28 MX MX2014011851A patent/MX358429B/es active IP Right Grant
- 2013-03-28 US US14/389,466 patent/US9249127B2/en active Active
- 2013-03-28 DK DK13719297.7T patent/DK2834233T3/en active
- 2013-03-28 LT LTEP13719297.7T patent/LT2834233T/lt unknown
- 2013-03-28 RU RU2014144284A patent/RU2642065C2/ru active
- 2013-03-29 TW TW102111298A patent/TWI620746B/zh active
-
2014
- 2014-09-15 IL IL234663A patent/IL234663B/en active IP Right Grant
-
2015
- 2015-06-16 HK HK15105661.0A patent/HK1205115A1/xx unknown
-
2018
- 2018-07-25 HR HRP20181203TT patent/HRP20181203T1/hr unknown
-
2022
- 2022-01-27 NO NO2022002C patent/NO2022002I1/no unknown
- 2022-01-31 NL NL301160C patent/NL301160I2/nl unknown
- 2022-01-31 FR FR22C1005C patent/FR22C1005I1/fr active Active
- 2022-02-02 HU HUS2200005C patent/HUS2200005I1/hu unknown
- 2022-02-03 LT LTPA2022001C patent/LTPA2022001I1/lt unknown
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