HUE038920T2 - Benzotiofén vegyület - Google Patents

Benzotiofén vegyület

Info

Publication number
HUE038920T2
HUE038920T2 HUE14807340A HUE14807340A HUE038920T2 HU E038920 T2 HUE038920 T2 HU E038920T2 HU E14807340 A HUE14807340 A HU E14807340A HU E14807340 A HUE14807340 A HU E14807340A HU E038920 T2 HUE038920 T2 HU E038920T2
Authority
HU
Hungary
Prior art keywords
benzothiophene compound
benzothiophene
compound
Prior art date
Application number
HUE14807340A
Other languages
English (en)
Inventor
Tsukasa Ishihara
Kazuhiro Ikegai
Ikumi Kuriwaki
Hiroyuki Hisamichi
Nobuaki Takeshita
Ryuichi Takezawa
Original Assignee
Astellas Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astellas Pharma Inc filed Critical Astellas Pharma Inc
Publication of HUE038920T2 publication Critical patent/HUE038920T2/hu

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/53751,4-Oxazines, e.g. morpholine
    • A61K31/53771,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4025Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4535Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom, e.g. pizotifen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/10Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
HUE14807340A 2013-06-06 2014-06-06 Benzotiofén vegyület HUE038920T2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2013119416 2013-06-06

Publications (1)

Publication Number Publication Date
HUE038920T2 true HUE038920T2 (hu) 2018-12-28

Family

ID=52005968

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE14807340A HUE038920T2 (hu) 2013-06-06 2014-06-06 Benzotiofén vegyület

Country Status (31)

Country Link
US (2) US8981119B2 (hu)
EP (1) EP3006443B1 (hu)
JP (1) JP6314978B2 (hu)
KR (1) KR102253721B1 (hu)
CN (1) CN105263926B (hu)
AR (1) AR096544A1 (hu)
AU (1) AU2014275768B2 (hu)
BR (1) BR112015030533B1 (hu)
CA (1) CA2914606C (hu)
CY (1) CY1120341T1 (hu)
DK (1) DK3006443T3 (hu)
ES (1) ES2671818T3 (hu)
HK (1) HK1215570A1 (hu)
HR (1) HRP20180722T1 (hu)
HU (1) HUE038920T2 (hu)
IL (1) IL242800B (hu)
LT (1) LT3006443T (hu)
MX (1) MX2015016743A (hu)
NO (1) NO3006443T3 (hu)
PH (1) PH12015502637A1 (hu)
PL (1) PL3006443T3 (hu)
PT (1) PT3006443T (hu)
RS (1) RS57250B1 (hu)
RU (1) RU2667507C2 (hu)
SG (1) SG11201509989VA (hu)
SI (1) SI3006443T1 (hu)
TR (1) TR201808724T4 (hu)
TW (1) TWI624466B (hu)
UA (1) UA117484C2 (hu)
WO (1) WO2014196644A1 (hu)
ZA (1) ZA201508866B (hu)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4003357A1 (en) * 2019-07-23 2022-06-01 Astellas Pharma Global Development, Inc. Methods of treating sleep disorders associated with pain

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5614639A (en) * 1995-03-31 1997-03-25 Eli Lilly And Company Process for preparing 2-substituted benzo[b]thiophene compounds and intermediates thereof
US20040116405A1 (en) 2001-02-06 2004-06-17 Brian Cox Use of bicyclic esters or amides for the treatment of diseases responsive to enhanced potassium channel activity
WO2003005025A1 (en) * 2001-07-03 2003-01-16 Biovitrum Ab Methods for identifying compounds modulating the activity of ppar-gamma
JP2006522130A (ja) * 2003-04-03 2006-09-28 メルク エンド カムパニー インコーポレーテッド ナトリウムチャンネル遮断薬としてのビアリール置換ピラゾール
JP2007523873A (ja) 2003-07-15 2007-08-23 スミスクライン・ビーチャム・コーポレイション 新規化合物
WO2008054435A2 (en) * 2006-01-09 2008-05-08 The Regents Of The University Of California Use of sk channel activators to prevent relapse/reinstatement of drugs of abuse
US8022209B2 (en) 2007-09-12 2011-09-20 Janssen Pharmaceutica Nv Substituted nitrogen-containing heteroaryl derivatives useful as modulators of the histamine H4 receptor
JP5783903B2 (ja) * 2008-11-10 2015-09-24 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 中間コンダクタンスカルシウム活性化カリウムチャネルを介して細胞間融合を調節するための組成物および方法
AR090037A1 (es) 2011-11-15 2014-10-15 Xention Ltd Derivados de tieno y/o furo-pirimidinas y piridinas inhibidores de los canales de potasio

Also Published As

Publication number Publication date
US20150133433A1 (en) 2015-05-14
TR201808724T4 (tr) 2018-07-23
AR096544A1 (es) 2016-01-13
RS57250B1 (sr) 2018-07-31
IL242800B (en) 2019-06-30
TW201536775A (zh) 2015-10-01
HK1215570A1 (zh) 2016-09-02
EP3006443A1 (en) 2016-04-13
UA117484C2 (uk) 2018-08-10
MX2015016743A (es) 2016-03-21
PL3006443T3 (pl) 2018-09-28
IL242800A0 (en) 2016-02-01
JP6314978B2 (ja) 2018-04-25
HRP20180722T1 (hr) 2018-06-15
EP3006443B1 (en) 2018-04-25
ZA201508866B (en) 2017-11-29
LT3006443T (lt) 2018-07-10
CA2914606A1 (en) 2014-12-11
PT3006443T (pt) 2018-06-07
ES2671818T3 (es) 2018-06-08
BR112015030533B1 (pt) 2023-02-28
BR112015030533A2 (pt) 2020-10-20
WO2014196644A1 (ja) 2014-12-11
TWI624466B (zh) 2018-05-21
PH12015502637B1 (en) 2016-03-07
SI3006443T1 (en) 2018-08-31
CN105263926A (zh) 2016-01-20
RU2015152150A (ru) 2017-07-13
DK3006443T3 (en) 2018-06-25
RU2667507C2 (ru) 2018-09-21
EP3006443A4 (en) 2016-12-21
US9399038B2 (en) 2016-07-26
AU2014275768A1 (en) 2015-12-17
AU2014275768B2 (en) 2017-12-14
SG11201509989VA (en) 2016-01-28
US8981119B2 (en) 2015-03-17
KR102253721B1 (ko) 2021-05-18
CA2914606C (en) 2021-03-23
JPWO2014196644A1 (ja) 2017-02-23
KR20160015281A (ko) 2016-02-12
CY1120341T1 (el) 2019-07-10
US20140364421A1 (en) 2014-12-11
CN105263926B (zh) 2018-05-11
NO3006443T3 (hu) 2018-09-22
PH12015502637A1 (en) 2016-03-07

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