HUE034297T2 - A HER-W interferencia csoportba tartozó vírus burka és hASCT receptor közötti kölcsönhatáshoz szükséges peptiddomén - Google Patents
A HER-W interferencia csoportba tartozó vírus burka és hASCT receptor közötti kölcsönhatáshoz szükséges peptiddomén Download PDFInfo
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- HUE034297T2 HUE034297T2 HUE07730950A HUE07730950A HUE034297T2 HU E034297 T2 HUE034297 T2 HU E034297T2 HU E07730950 A HUE07730950 A HU E07730950A HU E07730950 A HUE07730950 A HU E07730950A HU E034297 T2 HUE034297 T2 HU E034297T2
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- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
- C07K16/1036—Retroviridae, e.g. leukemia viruses
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- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
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Claims (9)
1, A HERV-W interferencia csoportba tartózó vírus burkának pepílddoménie, amely képes kölcsönhatásba lépni és hASCT receptorral, azzal jellemezve, hogy N-terminálissal kezdődik és ü-terminálisban végződik, és azzal, hogy: az M-terminálisí a SHQ I|> NOwi ~ SEQ 1D NO*29 közül választott motívum definiálja, a C-temnnáhst a HUV> ΙΠ N0°3ft - SBQ 10 NO°40 közül választolt motívum definiálja, és azzal, hogy a peptiddornén az N-terminális és C-terminális között legalább egy motívumot tartalmaz a SEQ 11) N0°41, SBQ 10 NC)°42 és SEQ ID NO:73 közül választva.
'2, Az 1. igém pont szerinti pepikbe Miiére azzal jellemezve, hogy immunválaszt indukál a 1ÍERV-W interferencia csoportba tartózó virus ellen és azzal, hogy a 3a ábrán bemutatott SF.Q 10 NO: 74 szekvenciája.
3. Monokionális ellenanyag, amely a igénypont szerinti peptiddornén ellen irányul.
4. Az 1. vagy 2. igénypont szerint definiált legalább egy peptiddornén vagy a .1. igénypont szerint definiált legalább egy ellenanyag alkalmazása a HERV-W interferencia csoportba tartózó vírus által állatban, előnyösen emberben okozott fertőzés gátlására, megelőzésére vagy kezelésére szánt gyógyszer előállítására.
5. Gyógyászati készítmény, amely hatóanyagként az. t. vagy 2, igénypont szerint definiált legalább egy pepíiddomént vagy a 3. igénypont szerint definiált legalább egy ellenanyagot tartalmaz, együtt gyógyászaülag elfogadható hordozóval,
6. Diagnosztikai készítmény a HERV-W interferencia csoportba tartózó virus detektálására és/vagy mennyiségi meghatározására és/vagy a 1OíRV-W interferencia csoportba tartózó virus ellent immunválasz mennyiségi meghatározására, anteh az 1. vagy 2. igénypont szerint definiált legalább egy pepíiddomént vagy a 3. igénypont szerint definiált legalább egy ellenanyagot tartalmaz.
7, {''{járás a .HER.V-W interferencia csoportba tartózó virus detektálására és/vagy mennyiségi meghatározására a vírussal feltehetőleg fertőzőit egyénből származó biológiai mintában, azzal jellemezve, hogy a következő lépéseket foglalja magában: - a biológiai minta érintkezletése legalább egy 3. igénypont szerinti ellenanyaggal olyan körülmények közöm amelyek lehetővé teszik komplex kialakulását a vírus és az ellenanyag között, és - a komplex, detektálását és/vagy menppsép meghatározását bármely megfelelő módszerrel,
8, A 6, igénypont szerinti készítmény alkalmazásai HERW^IIíiMféféftdip^pólii tartózó virus irt vitro diagnózisára biológiai mintában vagy gyűjtemény betű
9, Az 1. igénypont szerinti poptiddomén alkalmazása olyan kémiai vagy biológiai molekulák azonosítására, amelyek kölcsönhatása a peptiddomén égiszévé! vagy egy részével blokkolja a kölcsönhatást a 11KRV-W interferéhoía eáöpplba tartózó vírus burka és hASCT .receptor között.
Applications Claiming Priority (1)
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| FR0650468A FR2897062B1 (fr) | 2006-02-09 | 2006-02-09 | Domaine peptidique necessaire a l'interaction entre l'enveloppe d'un virus appartenant au groupe d'interference de herv-w et un recepteur asct |
Publications (1)
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| HUE034297T2 true HUE034297T2 (hu) | 2018-02-28 |
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Family Applications (1)
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| HUE07730950A HUE034297T2 (hu) | 2006-02-09 | 2007-02-09 | A HER-W interferencia csoportba tartozó vírus burka és hASCT receptor közötti kölcsönhatáshoz szükséges peptiddomén |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US20090148454A1 (hu) |
| EP (1) | EP1981904B9 (hu) |
| JP (2) | JP2009525741A (hu) |
| CN (1) | CN101379079B (hu) |
| AU (1) | AU2007213591B2 (hu) |
| CA (1) | CA2640793C (hu) |
| DK (1) | DK1981904T3 (hu) |
| ES (1) | ES2637961T3 (hu) |
| FR (1) | FR2897062B1 (hu) |
| HU (1) | HUE034297T2 (hu) |
| IL (1) | IL193353A (hu) |
| NO (1) | NO20083549L (hu) |
| PL (1) | PL1981904T3 (hu) |
| PT (1) | PT1981904T (hu) |
| WO (1) | WO2007090967A2 (hu) |
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|---|---|---|---|---|
| CN102326079B (zh) * | 2009-01-09 | 2015-04-15 | 国家科研中心 | 新型受体结合配体及其在检测具有生物学益处的细胞中的用途 |
| US20110287089A1 (en) | 2009-01-13 | 2011-11-24 | Karola Rittner | Use of a saccharomyces cerevisiae mitochondrial nucleic acids fraction for immune stimulation |
| US20180280549A1 (en) * | 2015-10-05 | 2018-10-04 | Metafora Biosystems | Receptor-binding domains ligands for the detection, diagnosis and treatment of pancreatic cancer |
| WO2024121254A1 (en) * | 2022-12-06 | 2024-06-13 | Metafora Biosystems | Ligands specific for asct1 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2710075B1 (fr) * | 1993-09-15 | 1995-10-27 | Bio Merieux | Réactif et procédé pour la détection d'une séquence nucléotidique avec amplification de signal. |
| FR2781802B1 (fr) * | 1998-07-31 | 2001-05-11 | Bio Merieux | Derives satures ou insatures de l'abietane, conjugues derives et utilisations dans une composition diagnostique, un reactif et un dispositif |
| FR2865403B1 (fr) * | 2004-01-23 | 2009-06-12 | Biomerieux Sa | Composition pour le traitement d'une pathologie associee a la msrv/herv-w |
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2006
- 2006-02-09 FR FR0650468A patent/FR2897062B1/fr active Active
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2007
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- 2007-02-09 JP JP2008553798A patent/JP2009525741A/ja active Pending
- 2007-02-09 HU HUE07730950A patent/HUE034297T2/hu unknown
- 2007-02-09 AU AU2007213591A patent/AU2007213591B2/en not_active Ceased
- 2007-02-09 EP EP07730950.8A patent/EP1981904B9/fr active Active
- 2007-02-09 US US12/087,893 patent/US20090148454A1/en not_active Abandoned
- 2007-02-09 PT PT77309508T patent/PT1981904T/pt unknown
- 2007-02-09 WO PCT/FR2007/000236 patent/WO2007090967A2/fr active Application Filing
- 2007-02-09 PL PL07730950T patent/PL1981904T3/pl unknown
- 2007-02-09 CN CN2007800046997A patent/CN101379079B/zh active Active
- 2007-02-09 CA CA2640793A patent/CA2640793C/fr active Active
- 2007-02-09 DK DK07730950.8T patent/DK1981904T3/en active
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2008
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- 2008-08-14 NO NO20083549A patent/NO20083549L/no not_active Application Discontinuation
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2015
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- 2015-10-08 JP JP2015200607A patent/JP6494487B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CN101379079A (zh) | 2009-03-04 |
| IL193353A (en) | 2016-06-30 |
| WO2007090967A2 (fr) | 2007-08-16 |
| CN101379079B (zh) | 2012-11-14 |
| WO2007090967A3 (fr) | 2007-12-21 |
| FR2897062B1 (fr) | 2011-11-04 |
| NO20083549L (no) | 2008-11-07 |
| JP2009525741A (ja) | 2009-07-16 |
| CA2640793A1 (fr) | 2007-08-16 |
| FR2897062A1 (fr) | 2007-08-10 |
| JP6494487B2 (ja) | 2019-04-03 |
| CA2640793C (fr) | 2015-11-24 |
| ES2637961T3 (es) | 2017-10-18 |
| EP1981904A2 (fr) | 2008-10-22 |
| US20090148454A1 (en) | 2009-06-11 |
| PT1981904T (pt) | 2017-07-11 |
| IL193353A0 (en) | 2011-08-01 |
| US20160090402A1 (en) | 2016-03-31 |
| AU2007213591A1 (en) | 2007-08-16 |
| US10040829B2 (en) | 2018-08-07 |
| EP1981904B9 (fr) | 2017-09-13 |
| AU2007213591B2 (en) | 2011-10-06 |
| JP2016040295A (ja) | 2016-03-24 |
| DK1981904T3 (en) | 2017-07-10 |
| PL1981904T3 (pl) | 2017-09-29 |
| EP1981904B1 (fr) | 2017-04-05 |
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