HU9700708D0 - Pyrimido[1,2-a]indole derivatives and process for producing them - Google Patents

Pyrimido[1,2-a]indole derivatives and process for producing them

Info

Publication number
HU9700708D0
HU9700708D0 HU9700708A HUP9700708A HU9700708D0 HU 9700708 D0 HU9700708 D0 HU 9700708D0 HU 9700708 A HU9700708 A HU 9700708A HU P9700708 A HUP9700708 A HU P9700708A HU 9700708 D0 HU9700708 D0 HU 9700708D0
Authority
HU
Hungary
Prior art keywords
pyrimido
producing
indole derivatives
indole
derivatives
Prior art date
Application number
HU9700708A
Other languages
English (en)
Inventor
Hilmar Bischoff
Dirk Denzer
Peter Eckenberg
Rudi Gruetzmann
Peter Kolkhof
Stefan Lohmer
Ulrich Mueller
Ulrich Nielsch
Stefan Wohlfeil
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of HU9700708D0 publication Critical patent/HU9700708D0/hu
Publication of HUP9700708A2 publication Critical patent/HUP9700708A2/hu
Publication of HUP9700708A3 publication Critical patent/HUP9700708A3/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cardiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
HU9700708A 1996-04-04 1997-04-04 N-[(9-pyrimido[1,2-a]indolyl)-methyl-phenylacetyl]-phenylglycinol derivatives, pharmaceutical compositions containing them, process for producing them and intermediates HUP9700708A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19613550A DE19613550A1 (de) 1996-04-04 1996-04-04 Neue Pyrimido[1,2-a]indole

Publications (3)

Publication Number Publication Date
HU9700708D0 true HU9700708D0 (en) 1997-05-28
HUP9700708A2 HUP9700708A2 (hu) 1998-10-28
HUP9700708A3 HUP9700708A3 (en) 2000-01-28

Family

ID=7790502

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9700708A HUP9700708A3 (en) 1996-04-04 1997-04-04 N-[(9-pyrimido[1,2-a]indolyl)-methyl-phenylacetyl]-phenylglycinol derivatives, pharmaceutical compositions containing them, process for producing them and intermediates

Country Status (33)

Country Link
US (1) US6114341A (hu)
EP (1) EP0799828A3 (hu)
JP (1) JPH1059972A (hu)
KR (1) KR970070008A (hu)
CN (2) CN1067393C (hu)
AR (1) AR006497A1 (hu)
AU (1) AU725786B2 (hu)
BG (1) BG62934B1 (hu)
BR (1) BR9701675A (hu)
CA (1) CA2201434A1 (hu)
CO (1) CO4520306A1 (hu)
CZ (1) CZ102297A3 (hu)
DE (1) DE19613550A1 (hu)
DZ (1) DZ2201A1 (hu)
EE (1) EE9700078A (hu)
HN (1) HN1997000045A (hu)
HR (1) HRP970154A2 (hu)
HU (1) HUP9700708A3 (hu)
ID (1) ID16520A (hu)
IL (3) IL131645A (hu)
MA (1) MA24131A1 (hu)
MY (1) MY126362A (hu)
NO (1) NO309092B1 (hu)
NZ (1) NZ314497A (hu)
PE (1) PE42398A1 (hu)
PL (1) PL319249A1 (hu)
SG (1) SG63698A1 (hu)
SK (1) SK42797A3 (hu)
SV (1) SV1997000025A (hu)
TN (1) TNSN97061A1 (hu)
TR (1) TR199700261A2 (hu)
YU (1) YU12397A (hu)
ZA (1) ZA972829B (hu)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19826469A1 (de) * 1998-06-13 2000-05-25 Bayer Ag Verfahren zur Herstellung von 2,4-Dimethylcarbolin und 2,4-Dimethylpyrimido[1,2-a]indol
WO2001074817A1 (fr) * 2000-03-30 2001-10-11 Yamanouchi Pharmaceutical Co., Ltd. Derives d'hydrazide
DE10030375A1 (de) * 2000-06-21 2002-01-03 Bayer Ag Verwendung von MTP-Inhibitoren zur Senkung von ppTRL
JP4254093B2 (ja) * 2001-10-17 2009-04-15 宇部興産株式会社 ５−ハロゲノインドールの製法
DE10349175A1 (de) * 2003-10-22 2005-05-19 Bayer Healthcare Ag Mittel zur Gewichtsreduktion
ES2399721T5 (es) 2004-03-05 2016-05-25 Univ Pennsylvania Métodos para tratar trastornos o enfermedades asociados a la hiperlipidemia e hipercolesterolemia minimizando los efectos adversos
US20080280922A1 (en) * 2004-04-09 2008-11-13 Marc Alois Celine Maria Engelen Intermittent Dosing Regimen For Overweight and Obese Subjects
CA3029306C (en) 2005-05-12 2020-12-29 C.R. Bard Inc. Removable embolus blood clot filter
EP1890767A2 (en) * 2005-05-27 2008-02-27 Pfizer Products Inc. Combination of a cannabinoid-1- receptor-antagonist and a microsomal triglyceride transfer protein inhibitor for treating obesity or mainataining weight loss
CA2616818C (en) 2005-08-09 2014-08-05 C.R. Bard, Inc. Embolus blood clot filter and delivery system
US20070088089A1 (en) * 2005-10-18 2007-04-19 Wisler Gerald L Methods for treating disorders associated with hyperlipidemia in a mammal
US10188496B2 (en) 2006-05-02 2019-01-29 C. R. Bard, Inc. Vena cava filter formed from a sheet
WO2008079398A1 (en) * 2006-12-21 2008-07-03 Aegerion Pharmaceuticals, Inc. Methods for treating obesity with a combination comprising a mtp inhibitor and a cholesterol absorption inhibitor

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA718536B (en) * 1971-01-11 1972-09-27 Wyeth John & Brother Ltd Heterocyclic compounds
DE2200584A1 (de) * 1971-01-11 1972-07-27 Wyeth John & Brother Ltd Heterocyclische Verbindungen,Verfahren zu ihrer Herstellung und ihre Verwendung in pharmazeutischen Zubereitungen
GB8614246D0 (en) * 1986-06-11 1986-07-16 Wyeth John & Brother Ltd Substituted pyrimidoindoles
DE4112533A1 (de) * 1991-04-17 1992-10-22 Bayer Ag Verfahren zur herstellung von enantiomerenreinen substituierten (chinolin-2-yl-methoxy)phenyl-essigsaeuren
DE4200954A1 (de) * 1991-04-26 1992-10-29 Bayer Ag Heterocyclisch substituierte phenylessigsaeurederivate
DE4208052A1 (de) * 1992-03-13 1993-09-16 Bayer Ag Imidazolyl substituierte phenylessigsaeureamide
US5576342A (en) * 1992-03-13 1996-11-19 Bayer Aktiengesellschaft Phenylglycinamides of heterocyclically substitued phenylacetic acid derivatives
DE4208051A1 (de) * 1992-03-13 1993-09-16 Bayer Ag Substituierte phenylessigsaeureamide
DE4309968A1 (de) * 1993-03-26 1994-09-29 Bayer Ag Phenylglycinamide von heterocyclisch substituierten Phenylessigsäurederivaten
KR950704328A (ko) * 1992-11-05 1995-11-17 데이비드 로버츠 5-HT₄ 수용체 길항제로서의 피페리딘 유도체(Piperidine Derivatives as 5-HT₄ Receptor Antagonists)
DE4302956A1 (de) * 1993-02-03 1994-08-04 Bayer Ag Substituierte Imidazo(4,5-b)pyridine und Benzimidazole

Also Published As

Publication number Publication date
DZ2201A1 (fr) 2002-12-03
CO4520306A1 (es) 1997-10-15
SG63698A1 (en) 1999-03-30
SV1997000025A (es) 1997-10-23
PL319249A1 (en) 1997-10-13
IL120590A (en) 2000-02-17
KR970070008A (ko) 1997-11-07
MA24131A1 (fr) 1997-10-01
AU1660397A (en) 1997-10-09
SK42797A3 (en) 1997-11-05
EP0799828A2 (de) 1997-10-08
EE9700078A (et) 1997-10-15
CZ102297A3 (en) 1997-10-15
TNSN97061A1 (fr) 2005-03-15
NO971512D0 (no) 1997-04-03
BG101379A (en) 1997-11-28
CN1176965A (zh) 1998-03-25
AR006497A1 (es) 1999-08-25
HUP9700708A2 (hu) 1998-10-28
ID16520A (id) 1997-10-09
NZ314497A (en) 1999-10-28
BG62934B1 (bg) 2000-11-30
HRP970154A2 (en) 1998-04-30
YU12397A (en) 1999-11-22
BR9701675A (pt) 1998-11-03
MX9702445A (es) 1997-10-31
HUP9700708A3 (en) 2000-01-28
NO971512L (no) 1997-10-06
CN1067393C (zh) 2001-06-20
IL131645A0 (en) 2001-01-28
DE19613550A1 (de) 1997-10-09
TR199700261A2 (xx) 1997-10-21
IL131645A (en) 2000-12-06
PE42398A1 (es) 1998-10-12
HN1997000045A (es) 1997-06-26
CA2201434A1 (en) 1997-10-04
NO309092B1 (no) 2000-12-11
MY126362A (en) 2006-09-29
ZA972829B (en) 1997-10-31
CN1312246A (zh) 2001-09-12
JPH1059972A (ja) 1998-03-03
EP0799828A3 (de) 1998-04-08
US6114341A (en) 2000-09-05
IL120590A0 (en) 1997-08-14
AU725786B2 (en) 2000-10-19

Similar Documents

Publication Publication Date Title
PL322623A1 (en) Derivatives of imidazo [1,2-a] pyridine
HU9702345D0 (en) 3-hydroxy-pyridine-2-carboxylic-amide-ester derivatives and process for producing them
HU9700708D0 (en) Pyrimido[1,2-a]indole derivatives and process for producing them
PL327539A1 (en) 2,7-substituted derivatives of octahydropyrrole[1,2-a]-pyrazine
IL120591A0 (en) Process for the preparation of enantiomerically pure cyclo-alkano-indol-and azaindol - and pyrimido [1,2a] indol carbocylic acids and their derivatives
GB9410441D0 (en) Azabicycloakyl derivatives of imidazo (1,5-a) indol-3-one and process for their preparation
AU5172296A (en) Pyrimido{4,5-b}indoles
HUP9701013A3 (en) Process for producing cephem-and isooxacephem derivatives
GB2316072B (en) Pyrrolo[3,2-c]quinoline derivatives
EP1008656A4 (en) METHOD FOR PRODUCING LH-RH DERIVATIVES
AU2742397A (en) Processes for producing 1,6-hexanedials and derivatives
AU1733297A (en) Novel tetrahydronaphthofuranone derivatives and process for producing the same
AU4503799A (en) Method for producing 2,4-dimethylcarboline and 2,4-dimethylpyrimido(1,2-a)indole
HUP9700724A3 (en) Process for producing substituted pyrimidin derivatives
HUP9700628A2 (en) 4-thia-1-aza-bicyclo[3.2.0]heptan-3-imino-2-izopropiliden-7-oxo-beta-lactame derivatives, process for producing them and use of them
HU9700502D0 (en) Orto-substituted benzoyl-guanidine derivatives, process for producing them and use of them
HU9700542D0 (en) Orto-substituted benzoyl-guanidine derivatives, process for producing them and use of them
AU4706397A (en) Method for producing 1,8-diaminonaphthalines and their 2,3-dihydroperimidine derivatives
HU0200040D0 (en) Thiazolo[3,2-a]azepine derivatives and process for their preparation
GB9518219D0 (en) Pyrrolo[3,2-C]Quinoline Derivatives
HU9700543D0 (en) Orto-substituted benzoyl-guanidine derivatives, process for producing them and use of them
HU0000337D0 (en) 8-amino-10-(azabicycloalkyl)-pyrido[1,2,3-d,e][1,3,4]benzoxadiazine derivatives and process producing them
GB9601759D0 (en) Dihydrophenanthrenone derivatives and process for their preparation
HUP0100429A3 (en) Pyrrolo[3,2-b]pyridine derivatives and process for the preparation of then and their intermediates
KR100199834B1 (en) Tetrahydroisoquinolinylcarbamates of 1,2,3,3a,8,8a-hexahydro-1,3a,8-trimethylpyrrolo[2,3-b]indole