HU9502178D0 - Piperazine derivatives for producing alkyl-trazodon derivatives and process for producing them - Google Patents

Piperazine derivatives for producing alkyl-trazodon derivatives and process for producing them

Info

Publication number
HU9502178D0
HU9502178D0 HU9502178A HU9502178A HU9502178D0 HU 9502178 D0 HU9502178 D0 HU 9502178D0 HU 9502178 A HU9502178 A HU 9502178A HU 9502178 A HU9502178 A HU 9502178A HU 9502178 D0 HU9502178 D0 HU 9502178D0
Authority
HU
Hungary
Prior art keywords
producing
derivatives
trazodon
alkyl
piperazine
Prior art date
Application number
HU9502178A
Other languages
English (en)
Other versions
HUT71512A (en
HU217981B (hu
Inventor
Leandro Baiocchi
Original Assignee
Angelini Francesco Ist Ricerca
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Angelini Francesco Ist Ricerca filed Critical Angelini Francesco Ist Ricerca
Priority to HU9502178A priority Critical patent/HU217981B/hu
Publication of HU9502178D0 publication Critical patent/HU9502178D0/hu
Publication of HUT71512A publication Critical patent/HUT71512A/hu
Publication of HU217981B publication Critical patent/HU217981B/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/06Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
    • C07D295/073Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/06Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
    • C07C229/10Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings
    • C07C229/16Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of hydrocarbon radicals substituted by amino or carboxyl groups, e.g. ethylenediamine-tetra-acetic acid, iminodiacetic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/06Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
    • C07D295/067Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HU9502178A 1992-01-17 1995-07-19 N-(3-klór-fenil)-piperazin-származékok és eljárás ezek előállítására HU217981B (hu)

Priority Applications (1)

Application Number Priority Date Filing Date Title
HU9502178A HU217981B (hu) 1992-01-17 1995-07-19 N-(3-klór-fenil)-piperazin-származékok és eljárás ezek előállítására

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ITMI920084A IT1258790B (it) 1992-01-17 1992-01-17 Alchil derivati del trazodone
HU9402119A HU218678B (hu) 1992-01-17 1993-01-14 Központi idegrendszerre ható alkil-trazodon-származékok, ezeket tartalmazó gyógyszerkészítmények és eljárás előállításukra
HU9502178A HU217981B (hu) 1992-01-17 1995-07-19 N-(3-klór-fenil)-piperazin-származékok és eljárás ezek előállítására

Publications (3)

Publication Number Publication Date
HU9502178D0 true HU9502178D0 (en) 1995-09-28
HUT71512A HUT71512A (en) 1995-12-28
HU217981B HU217981B (hu) 2000-05-28

Family

ID=11361589

Family Applications (5)

Application Number Title Priority Date Filing Date
HU9402119A HU218678B (hu) 1992-01-17 1993-01-14 Központi idegrendszerre ható alkil-trazodon-származékok, ezeket tartalmazó gyógyszerkészítmények és eljárás előállításukra
HU9502179A HU217968B (hu) 1992-01-17 1993-01-14 Alkil-trazodon-származékok előállítására alkalmazható piperazinonszármazékok és eljárás előállításukra
HU9502177A HU219493B (hu) 1992-01-17 1995-07-19 Alkil-trazodon-származékok előállítására alkalmazható piperazinszármazékok és eljárás előállításukra
HU9502180A HU217982B (hu) 1992-01-17 1995-07-19 Alkil-trazodon-származékok előállításánál alkalmazható 2-helyettesített-(3-klór-fenil)-3,6-diaza-hexánsav-származékok és eljárás ezek előállítására
HU9502178A HU217981B (hu) 1992-01-17 1995-07-19 N-(3-klór-fenil)-piperazin-származékok és eljárás ezek előállítására

Family Applications Before (4)

Application Number Title Priority Date Filing Date
HU9402119A HU218678B (hu) 1992-01-17 1993-01-14 Központi idegrendszerre ható alkil-trazodon-származékok, ezeket tartalmazó gyógyszerkészítmények és eljárás előállításukra
HU9502179A HU217968B (hu) 1992-01-17 1993-01-14 Alkil-trazodon-származékok előállítására alkalmazható piperazinonszármazékok és eljárás előállításukra
HU9502177A HU219493B (hu) 1992-01-17 1995-07-19 Alkil-trazodon-származékok előállítására alkalmazható piperazinszármazékok és eljárás előállításukra
HU9502180A HU217982B (hu) 1992-01-17 1995-07-19 Alkil-trazodon-származékok előállításánál alkalmazható 2-helyettesített-(3-klór-fenil)-3,6-diaza-hexánsav-származékok és eljárás ezek előállítására

Country Status (25)

Country Link
EP (1) EP0623131B1 (hu)
JP (1) JP2856912B2 (hu)
KR (1) KR100254690B1 (hu)
AT (1) ATE136307T1 (hu)
AU (1) AU671973B2 (hu)
BG (1) BG61841B1 (hu)
BR (1) BR9305752A (hu)
CA (1) CA2128202C (hu)
CZ (1) CZ282910B6 (hu)
DE (1) DE69302087T2 (hu)
DK (1) DK0623131T3 (hu)
ES (1) ES2088270T3 (hu)
FI (2) FI110186B (hu)
GE (1) GEP20001939B (hu)
GR (1) GR3020420T3 (hu)
HU (5) HU218678B (hu)
IT (1) IT1258790B (hu)
NO (2) NO302365B1 (hu)
NZ (1) NZ246598A (hu)
PL (1) PL170913B1 (hu)
RO (1) RO113465B1 (hu)
RU (1) RU2126801C1 (hu)
SK (1) SK280561B6 (hu)
WO (1) WO1993014091A1 (hu)
ZA (1) ZA93292B (hu)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU718075B2 (en) * 1993-07-01 2000-04-06 Angelini Ricerche S.P.A. Societa Consortile Intermediates for the preparation of pharmacologically active enantiomers of triazolone compounds
IT1268414B1 (it) * 1993-07-01 1997-02-27 Angelini Francesco Ist Ricerca Enantiomeri farmacologicamente attivi
TW200726765A (en) * 2005-06-17 2007-07-16 Bristol Myers Squibb Co Triazolopyridine cannabinoid receptor 1 antagonists
ITMI20051193A1 (it) 2005-06-24 2006-12-25 Acraf Uso farmaceutico di una 1-3-clorofenil-3-alchilpiperazina
WO2012072665A1 (en) 2010-11-30 2012-06-07 Pharmaneuroboost N.V. Compositions comprising pipamperone and serotonin antagonist reuptake inhibitors
RU2706700C1 (ru) 2019-09-24 2019-11-20 Общество с ограниченной ответственностью "Научно-производственная компания "СКиФФ" Фармацевтическая композиция для коррекции поведения кошек и собак в стрессовых ситуациях

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US100505A (en) * 1870-03-08 Improvement in sash-bolt
IT1066857B (it) * 1965-12-15 1985-03-12 Acraf Derivati della s ipiazolo 4.3 a piridina e processi per la loro preparazione

Also Published As

Publication number Publication date
ZA93292B (en) 1993-08-19
CZ173294A3 (en) 1995-02-15
FI20021652A (fi) 2002-09-16
JPH07503000A (ja) 1995-03-30
BG61841B1 (bg) 1998-07-31
HUT71512A (en) 1995-12-28
HU217982B (hu) 2000-05-28
AU3350493A (en) 1993-08-03
HUT71513A (en) 1995-12-28
HU217968B (hu) 2000-05-28
WO1993014091A1 (en) 1993-07-22
NZ246598A (en) 1997-08-22
HU9502177D0 (en) 1995-09-28
FI943386A0 (fi) 1994-07-15
HU219493B (hu) 2001-04-28
SK84694A3 (en) 1995-04-12
ITMI920084A1 (it) 1993-07-17
GEP20001939B (en) 2000-02-05
HUT70761A (en) 1995-10-30
HUT71511A (en) 1995-12-28
CZ282910B6 (cs) 1997-11-12
AU671973B2 (en) 1996-09-19
RU94036769A (ru) 1997-04-20
ATE136307T1 (de) 1996-04-15
PL170913B1 (pl) 1997-02-28
ES2088270T3 (es) 1996-08-01
FI113266B (fi) 2004-03-31
NO303686B1 (no) 1998-08-17
DK0623131T3 (da) 1996-08-05
RU2126801C1 (ru) 1999-02-27
BG98896A (bg) 1995-03-31
NO942668D0 (no) 1994-07-15
NO974462D0 (no) 1997-09-26
HU9502180D0 (en) 1995-09-28
RO113465B1 (ro) 1998-07-30
HU9402119D0 (en) 1994-09-28
DE69302087T2 (de) 1996-11-28
FI943386A (fi) 1994-07-15
HU218678B (hu) 2000-10-28
CA2128202A1 (en) 1993-07-22
HUT72591A (en) 1996-05-28
BR9305752A (pt) 1997-01-28
NO974462L (no) 1994-09-16
EP0623131A1 (en) 1994-11-09
KR100254690B1 (ko) 2000-05-01
IT1258790B (it) 1996-02-29
NO302365B1 (no) 1998-02-23
CA2128202C (en) 2001-01-23
NO942668L (no) 1994-09-16
EP0623131B1 (en) 1996-04-03
SK280561B6 (sk) 2000-03-13
GR3020420T3 (en) 1996-10-31
HU9502179D0 (en) 1995-09-28
ITMI920084A0 (it) 1992-01-17
FI110186B (fi) 2002-12-13
JP2856912B2 (ja) 1999-02-10
DE69302087D1 (de) 1996-05-09
HU217981B (hu) 2000-05-28

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Legal Events

Date Code Title Description
MM4A Lapse of definitive patent protection due to non-payment of fees