HU9303774D0 - Pyridopyrimidine derivatives, their production and use - Google Patents

Pyridopyrimidine derivatives, their production and use

Info

Publication number
HU9303774D0
HU9303774D0 HU9303774A HU9303774A HU9303774D0 HU 9303774 D0 HU9303774 D0 HU 9303774D0 HU 9303774 A HU9303774 A HU 9303774A HU 9303774 A HU9303774 A HU 9303774A HU 9303774 D0 HU9303774 D0 HU 9303774D0
Authority
HU
Hungary
Prior art keywords
denotes
integer
endothelin receptor
production
hypertension
Prior art date
Application number
HU9303774A
Other languages
English (en)
Other versions
HUT66159A (en
HU218782B (hu
Inventor
Shuichi Furuya
Tetsuya Ohtaki
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of HU9303774D0 publication Critical patent/HU9303774D0/hu
Publication of HUT66159A publication Critical patent/HUT66159A/hu
Publication of HU218782B publication Critical patent/HU218782B/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
HU9303774A 1992-12-29 1993-12-28 Piridopirimidinszármazékok, ezeket tartalmazó gyógyszerkészítmények és eljárás előállításukra HU218782B (hu)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP36038492 1992-12-29
JP27713693 1993-11-05

Publications (3)

Publication Number Publication Date
HU9303774D0 true HU9303774D0 (en) 1994-04-28
HUT66159A HUT66159A (en) 1994-09-28
HU218782B HU218782B (hu) 2000-12-28

Family

ID=26552272

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9303774A HU218782B (hu) 1992-12-29 1993-12-28 Piridopirimidinszármazékok, ezeket tartalmazó gyógyszerkészítmények és eljárás előállításukra

Country Status (12)

Country Link
US (1) US5654309A (hu)
EP (1) EP0608565B1 (hu)
KR (1) KR940014398A (hu)
CN (1) CN1041090C (hu)
AT (1) ATE214391T1 (hu)
CA (1) CA2112425A1 (hu)
DE (1) DE69331688T2 (hu)
FI (1) FI935897A (hu)
HU (1) HU218782B (hu)
NO (1) NO301762B1 (hu)
RU (1) RU2127734C1 (hu)
TW (1) TW299333B (hu)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0626174A3 (en) * 1993-04-21 1996-01-03 Takeda Chemical Industries Ltd Method and composition for the prophylaxis and / or treatment of underactive organs.
NZ322197A (en) * 1995-11-21 1999-02-25 Yamanouchi Pharma Co Ltd Pyrido[2,3-d] pyrimidine derivatives and pharmaceutical compositions thereof
KR100377788B1 (ko) * 2000-12-29 2003-03-26 씨제이 주식회사 신규한 피리도피리미딘 유도체, 그 제조방법 및 이를포함하는 약제학적 조성물
KR100377787B1 (ko) * 2000-12-29 2003-03-26 씨제이 주식회사 신규한 피리도피리미딘 유도체, 그 제조방법 및 이를포함하는 약제학적 조성물
DE10110747A1 (de) 2001-03-07 2002-09-12 Bayer Ag Substituierte 2,6-Diamino-3,5-dicyano-4-aryl-pyridine und ihre Verwendung
US6825180B2 (en) * 2001-05-18 2004-11-30 Cell Therapeutics, Inc. Pyridopyrimidine compounds and their uses
WO2006019965A2 (en) * 2004-07-16 2006-02-23 Takeda San Diego, Inc. Dipeptidyl peptidase inhibitors
DE102004042607A1 (de) 2004-09-03 2006-03-09 Bayer Healthcare Ag Substituierte Phenylaminothiazole und ihre Verwendung
US20100022568A1 (en) * 2006-04-13 2010-01-28 Actelion Pharmaceeuticals Ltd. Endothelin receptor antagonists for early stage idiopathic pulmonary fibrosis
DE102006042143A1 (de) 2006-09-08 2008-03-27 Bayer Healthcare Aktiengesellschaft Neue substituierte Bipyridin-Derivate und ihre Verwendung
DE102006056739A1 (de) 2006-12-01 2008-06-05 Bayer Healthcare Ag Substituierte 4-Amino-3,5-dicyano-2-thiopyridine und ihre Verwendung
DE102006056740A1 (de) 2006-12-01 2008-06-05 Bayer Healthcare Ag Cyclisch substituierte 3,5-Dicyano-2-thiopyridine und ihre Verwendung
SA08280783B1 (ar) * 2007-01-11 2011-04-24 استرازينيكا ايه بي مشتقات بيريدوبيريميدين كمثبطات pde4
DE102007035367A1 (de) 2007-07-27 2009-01-29 Bayer Healthcare Ag Substituierte Aryloxazole und ihre Verwendung
DE102007036076A1 (de) 2007-08-01 2009-02-05 Bayer Healthcare Aktiengesellschaft Dipeptoid-Produgs und ihre Verwendung
DE102007061763A1 (de) 2007-12-20 2009-06-25 Bayer Healthcare Ag Substituierte azabicyclische Verbindungen und ihre Verwendung
DE102007061764A1 (de) 2007-12-20 2009-06-25 Bayer Healthcare Ag Anellierte Cyanopyridine und ihre Verwendung
DE102008013587A1 (de) 2008-03-11 2009-09-17 Bayer Schering Pharma Aktiengesellschaft Heteroaryl-substituierte Dicyanopyridine und ihre Verwendung
ES2428818T3 (es) 2008-05-29 2013-11-11 Bayer Intellectual Property Gmbh Dicianopiridinas sustituidas con 2-alcoxi y su uso
DE102008062567A1 (de) 2008-12-16 2010-06-17 Bayer Schering Pharma Aktiengesellschaft Dipeptoid-Prodrugs und ihre Verwendung
DE102009006602A1 (de) 2009-01-29 2010-08-05 Bayer Schering Pharma Aktiengesellschaft Alkylamino-substituierte Dicyanopyridine und deren Aminosäureester-Prodrugs
EP2266984A1 (en) * 2009-06-26 2010-12-29 Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts Pyrido[2,3-d]pyrimidines as Wnt antagonists for treatment of cancer and arthritis
DE102010030688A1 (de) 2010-06-30 2012-01-05 Bayer Schering Pharma Aktiengesellschaft Substituierte Dicyanopyridine und ihre Verwendung
US20120058983A1 (en) 2010-09-02 2012-03-08 Bayer Pharma Aktiengesellschaft Adenosine A1 agonists for the treatment of glaucoma and ocular hypertension
CN107245074B (zh) * 2017-06-20 2019-04-09 牡丹江医学院附属红旗医院 用于治疗脑梗死的化合物及其制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5649917B2 (hu) * 1973-12-18 1981-11-25
JPS5758347B2 (hu) * 1974-04-03 1982-12-09 Hisamitsu Pharmaceutical Co
DE3601731A1 (de) * 1986-01-22 1987-07-23 Merck Patent Gmbh Pyrimidinderivate
WO1992012979A1 (en) * 1991-01-17 1992-08-06 Pfizer Inc. 2,4-DIOXO-PYRIDO [2,3-d]PYRIMIDINE-3-ACETIC ACIDS AND ESTERS AND SALTS THEREOF
TW270116B (hu) * 1991-04-25 1996-02-11 Hoffmann La Roche

Also Published As

Publication number Publication date
US5654309A (en) 1997-08-05
KR940014398A (ko) 1994-07-18
NO301762B1 (no) 1997-12-08
CN1041090C (zh) 1998-12-09
EP0608565B1 (en) 2002-03-13
NO934866L (no) 1994-06-30
ATE214391T1 (de) 2002-03-15
EP0608565A1 (en) 1994-08-03
NO934866D0 (no) 1993-12-28
HUT66159A (en) 1994-09-28
HU218782B (hu) 2000-12-28
CA2112425A1 (en) 1994-06-30
RU2127734C1 (ru) 1999-03-20
DE69331688D1 (de) 2002-04-18
FI935897A (fi) 1994-06-30
FI935897A0 (fi) 1993-12-28
CN1094045A (zh) 1994-10-26
DE69331688T2 (de) 2002-09-12
TW299333B (hu) 1997-03-01

Similar Documents

Publication Publication Date Title
HU9303774D0 (en) Pyridopyrimidine derivatives, their production and use
RU93056846A (ru) Производные пиридопиримидина, их получение, фармацевтическая композиция, способ лечения
HUT76476A (en) Morpholine and thiomorpholine derivatives, process for the preparation thereof and pharmaceutical compositions containing them
FI990387A0 (fi) Tienopyrimidiinijohdannaiset, niiden valmistus ja käyttö
CA2065644A1 (en) Pyrazolopyridine compound and processes for preparation thereof
HU9801950D0 (en) 2-(arylphenyl)-amino-imidazoline derivatives
TNSN04106A1 (en) Triazolo-quinolin derivatives useful as adenosine receptor ligands
KR960041154A (ko) 플루오르 함유 벤조일구아니딘 유도체
TNSN04105A1 (en) Imidazoquinoline derivatives
ES2170758T3 (es) Antibioticos novedosos de cefalosporina y procedimientos para la preparacion de los mismos.
CA2015730A1 (en) Esters of phenylalkanoic acid
HUT74620A (en) 3-(indol-3-yl) propenoic acid derivatives as nmda antagonists and use of them for producing pharmaceutical compositions
DE69327380T2 (de) Antibiotische Pyrrolidinylthiopenemderivate
ES8702399A1 (es) Un procedimiento para preparar derivdos de 1,5-benzoxatiepina
JPS55105620A (en) Calcium antagonist
JPS55105619A (en) Calcium antagonist

Legal Events

Date Code Title Description
HMM4 Cancellation of final prot. due to non-payment of fee