DE69327380T2 - Antibiotische Pyrrolidinylthiopenemderivate - Google Patents

Antibiotische Pyrrolidinylthiopenemderivate

Info

Publication number
DE69327380T2
DE69327380T2 DE69327380T DE69327380T DE69327380T2 DE 69327380 T2 DE69327380 T2 DE 69327380T2 DE 69327380 T DE69327380 T DE 69327380T DE 69327380 T DE69327380 T DE 69327380T DE 69327380 T2 DE69327380 T2 DE 69327380T2
Authority
DE
Germany
Prior art keywords
pyrrolidinylthiopenem
antibiotic
derivatives
4alkyl
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69327380T
Other languages
English (en)
Other versions
DE69327380D1 (de
Inventor
Patrice Jean Siret
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca SAS
Syngenta Ltd
Original Assignee
Zeneca Pharma SA
Zeneca Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zeneca Pharma SA, Zeneca Ltd filed Critical Zeneca Pharma SA
Application granted granted Critical
Publication of DE69327380D1 publication Critical patent/DE69327380D1/de
Publication of DE69327380T2 publication Critical patent/DE69327380T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D499/00Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/88Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/568Four-membered rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE69327380T 1992-10-07 1993-10-01 Antibiotische Pyrrolidinylthiopenemderivate Expired - Fee Related DE69327380T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP92402733 1992-10-07

Publications (2)

Publication Number Publication Date
DE69327380D1 DE69327380D1 (de) 2000-01-27
DE69327380T2 true DE69327380T2 (de) 2000-05-11

Family

ID=8211717

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69327380T Expired - Fee Related DE69327380T2 (de) 1992-10-07 1993-10-01 Antibiotische Pyrrolidinylthiopenemderivate

Country Status (8)

Country Link
US (1) US5538962A (de)
EP (1) EP0592167B1 (de)
JP (1) JPH06211871A (de)
KR (1) KR100292395B1 (de)
AT (1) ATE187968T1 (de)
CA (1) CA2106330A1 (de)
DE (1) DE69327380T2 (de)
ES (1) ES2140445T3 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9515975D0 (en) 1995-08-04 1995-10-04 Zeneca Ltd Chemical compounds
DE69728883T2 (de) 1996-07-17 2005-04-07 Merck & Co., Inc. Änderung des zirkadischen rhythmus mit nicht-peptidischen neurokinin-1 rezeptor antagonisten
WO1998007692A1 (en) 1996-08-17 1998-02-26 Zeneca Limited 3-mercaptopyrrolidines as farnesyl protein transferase inhibitors
GB9930317D0 (en) 1999-12-22 2000-02-09 Zeneca Ltd Novel compounds
GB9930318D0 (en) 1999-12-22 2000-02-09 Zeneca Ltd Novel compounds

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1283906C (en) * 1983-05-09 1991-05-07 Makoto Sunagawa .beta.-LACTAM COMPOUNDS AND PRODUCTION THEREOF
IE910606A1 (en) * 1990-02-23 1991-08-28 Sankyo Co Carbapenem derivatives having antibiotic activity, their¹preparation and their use
GB9107341D0 (en) * 1991-04-08 1991-05-22 Ici Plc Antibiotic compounds
GB9202298D0 (en) * 1992-02-04 1992-03-18 Ici Plc Antibiotic compounds
GB9304156D0 (en) * 1992-03-26 1993-04-21 Zeneca Ltd Antibiotic compounds

Also Published As

Publication number Publication date
ES2140445T3 (es) 2000-03-01
ATE187968T1 (de) 2000-01-15
EP0592167A1 (de) 1994-04-13
KR940009189A (ko) 1994-05-20
EP0592167B1 (de) 1999-12-22
JPH06211871A (ja) 1994-08-02
DE69327380D1 (de) 2000-01-27
US5538962A (en) 1996-07-23
CA2106330A1 (en) 1994-04-08
KR100292395B1 (ko) 2001-09-17

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee