JO1777B1 - Antibiotic compounds - Google Patents
Antibiotic compoundsInfo
- Publication number
- JO1777B1 JO1777B1 JO19931777A JOP19931777A JO1777B1 JO 1777 B1 JO1777 B1 JO 1777B1 JO 19931777 A JO19931777 A JO 19931777A JO P19931777 A JOP19931777 A JO P19931777A JO 1777 B1 JO1777 B1 JO 1777B1
- Authority
- JO
- Jordan
- Prior art keywords
- 4alkyl
- amino
- hydrogen
- preparation
- thienyl ring
- Prior art date
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
The present invention relates to carbapenems and provides a compound of the formula (I) (I) wherein: R1 is 1-hydroxyethyl, 1-fluoroethyl or hydroxymethyl; R2 is hydrogen or C1-4alkyl; R3 is hydrogen or C1-4alkyl; and the thienyl ring is optionally further substitued by one or two substituents selected from halo, cyano, C1-4alkyl, nitro, hydroxy, carboxy, C1-4alkoxy, trifluoromethyl, C1-4alkoxycarbonyl, amino, C1-4alkylamino, di-C1-4alkylamino, sulfonic acid, C1-4alkylS(O)n- (wherein n is 0-2), C1-4alkanoylamino, C1-4alkanoyl(N-C1-4alkyl)amino, carbamoyl, C1-4alkylcarbamoyl, di-C1-4alkylcarbamoyl and N-C1-4alkanesulfonamido; or by a tetramethylene group attached to adjacent carbon atoms on the thienyl ring; or a pharmaceutically acceptable salt or in vivo hydrolysable ester thereof. Processes for their preparation, intermediates in their preparation, their use as therapeutic agents and pharmaceutical compositions containing them are also described.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JO19931777A JO1777B1 (en) | 1993-11-11 | 1993-11-11 | Antibiotic compounds |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JO19931777A JO1777B1 (en) | 1993-11-11 | 1993-11-11 | Antibiotic compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JO1777B1 true JO1777B1 (en) | 1994-05-15 |
Family
ID=48092618
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JO19931777A JO1777B1 (en) | 1993-11-11 | 1993-11-11 | Antibiotic compounds |
Country Status (1)
| Country | Link |
|---|---|
| JO (1) | JO1777B1 (en) |
-
1993
- 1993-11-11 JO JO19931777A patent/JO1777B1/en active
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