HU9204130D0 - Thiazolodine derivatives, method for producing them and pharmaceutical preparatives containing such compounds - Google Patents

Thiazolodine derivatives, method for producing them and pharmaceutical preparatives containing such compounds

Info

Publication number
HU9204130D0
HU9204130D0 HU9204130A HU9204130A HU9204130D0 HU 9204130 D0 HU9204130 D0 HU 9204130D0 HU 9204130 A HU9204130 A HU 9204130A HU 9204130 A HU9204130 A HU 9204130A HU 9204130 D0 HU9204130 D0 HU 9204130D0
Authority
HU
Hungary
Prior art keywords
alkyl
hydrogen
compounds
thiazolodine
derivatives
Prior art date
Application number
HU9204130A
Other languages
English (en)
Other versions
HU215450B (hu
HUT67788A (en
Inventor
Takao Yoshioka
Takahide Nishi
Tsutomu Kanai
Yuichi Aizawa
Kunio Wada
Takashi Fujita
Hiroyoshi Horikoshi
Original Assignee
Sankyo Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co filed Critical Sankyo Co
Publication of HU9204130D0 publication Critical patent/HU9204130D0/hu
Publication of HUT67788A publication Critical patent/HUT67788A/hu
Publication of HU215450B publication Critical patent/HU215450B/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/34Oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
HUP9204130A 1991-12-26 1992-12-23 Eljárás 2,4-dioxo-tiazolidin-származékok előállítására HU215450B (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP34457191 1991-12-26

Publications (3)

Publication Number Publication Date
HU9204130D0 true HU9204130D0 (en) 1993-04-28
HUT67788A HUT67788A (en) 1995-04-28
HU215450B HU215450B (hu) 1999-04-28

Family

ID=18370304

Family Applications (1)

Application Number Title Priority Date Filing Date
HUP9204130A HU215450B (hu) 1991-12-26 1992-12-23 Eljárás 2,4-dioxo-tiazolidin-származékok előállítására

Country Status (21)

Country Link
EP (1) EP0549365B1 (hu)
JP (1) JP2833949B2 (hu)
CN (1) CN1032751C (hu)
AT (1) ATE126221T1 (hu)
AU (1) AU654223B2 (hu)
CA (1) CA2086277A1 (hu)
CZ (1) CZ389792A3 (hu)
DE (1) DE69204041T2 (hu)
DK (1) DK0549365T3 (hu)
ES (1) ES2078671T3 (hu)
FI (1) FI925849A (hu)
GR (1) GR3017632T3 (hu)
HK (1) HK196095A (hu)
HU (1) HU215450B (hu)
IL (1) IL104238A (hu)
MX (1) MX9207595A (hu)
NO (1) NO302471B1 (hu)
NZ (1) NZ245612A (hu)
RU (1) RU2095354C1 (hu)
TW (1) TW211007B (hu)
ZA (1) ZA9210021B (hu)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO302519B1 (no) * 1991-12-26 1998-03-16 Sankyo Co Tiazolidinforbindelser som inneholder en kinongruppe, og farmasöytisk preparat
EP0783888A1 (en) * 1995-12-26 1997-07-16 Sankyo Company Limited Use of troglitazone and related thiazolidinediones in the manufacture of a medicament for the treatment and prophylaxis of osteoporosis
US6331633B1 (en) * 1998-05-08 2001-12-18 Calyx Therapeutics Inc. Heterocyclic analogs of diphenylethylene compounds
US6620830B2 (en) 2000-04-21 2003-09-16 Pfizer, Inc. Thyroid receptor ligands
EP1148054B1 (en) * 2000-04-21 2005-11-23 Pfizer Products Inc. Thyroid receptor ligands
WO2001081328A2 (en) * 2000-04-24 2001-11-01 Aryx Therapeutics Thiazolidinedione analogues and their use for the treatment of diabetes
US6768008B2 (en) 2000-04-24 2004-07-27 Aryx Therapeutics Materials and methods for the treatment of diabetes, hyperlipidemia, hypercholesterolemia, and atherosclerosis
US6680387B2 (en) 2000-04-24 2004-01-20 Aryx Therapeutics Materials and methods for the treatment of diabetes, hyperlipidemia, hypercholesterolemia, and atherosclerosis
JP2003040877A (ja) * 2001-07-24 2003-02-13 Sumika Fine Chemicals Co Ltd 5−[6−(2−フルオロベンジルオキシ)−2−ナフチル]メチル−2,4−チアゾリジンジオンの製造方法及びその精製方法
CN101454006B (zh) 2006-03-16 2012-12-26 新陈代谢解决方案开发公司 用于治疗高血压以及用于降低血脂的噻唑烷二酮类似物
CA2646207C (en) 2006-03-16 2016-01-19 Metabolic Solutions Development Company Thiazolidinedione analogues for the treatment of metabolic inflammation mediated disease
US8304441B2 (en) 2007-09-14 2012-11-06 Metabolic Solutions Development Company, Llc Thiazolidinedione analogues for the treatment of metabolic diseases
CA2699289C (en) * 2007-09-14 2016-01-19 Metabolic Solutions Development Company Thiazolidinedione analogues for the treatment of hypertension
US8912335B2 (en) 2009-12-15 2014-12-16 Metabolic Solutions Development Company, Llc PPAR-sparing thiazolidinedione salts for the treatment of metabolic diseases
WO2011133442A1 (en) * 2010-04-19 2011-10-27 Metabolic Solutions Development Company Novel synthesis for thiazolidinedione compounds
US20130281414A1 (en) * 2010-04-21 2013-10-24 Metabolic Solutions Development Company, Llc Thiazolidinedione analogues
EP2603498B1 (en) 2010-08-10 2016-11-09 Octeta Therapeutics, LLC Novel synthesis for thiazolidinedione compounds
CN115433144B (zh) * 2022-10-09 2023-09-19 燃点(南京)生物医药科技有限公司 一种脂肪酸酯类化合物及其制备方法和应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5522636A (en) * 1978-08-04 1980-02-18 Takeda Chem Ind Ltd Thiazoliding derivative
JPS6051189A (ja) * 1983-08-30 1985-03-22 Sankyo Co Ltd チアゾリジン誘導体およびその製造法
JPH06779B2 (ja) * 1985-06-10 1994-01-05 武田薬品工業株式会社 チアゾリジオン誘導体およびそれを含んでなる医薬組成物
US5143930A (en) * 1990-02-07 1992-09-01 Sankyo Company, Limited Thiazolidine derivatives with anti-diabetic activity, their preparation and their use
NO302519B1 (no) * 1991-12-26 1998-03-16 Sankyo Co Tiazolidinforbindelser som inneholder en kinongruppe, og farmasöytisk preparat

Also Published As

Publication number Publication date
DK0549365T3 (da) 1995-12-18
DE69204041T2 (de) 1996-03-28
NZ245612A (en) 1994-06-27
AU3043192A (en) 1993-07-01
IL104238A (en) 1996-10-31
EP0549365B1 (en) 1995-08-09
EP0549365A1 (en) 1993-06-30
NO924964D0 (no) 1992-12-22
RU2095354C1 (ru) 1997-11-10
ATE126221T1 (de) 1995-08-15
JPH05239041A (ja) 1993-09-17
AU654223B2 (en) 1994-10-27
ES2078671T3 (es) 1995-12-16
HU215450B (hu) 1999-04-28
FI925849A (fi) 1993-06-27
DE69204041D1 (de) 1995-09-14
FI925849A0 (fi) 1992-12-23
CZ389792A3 (en) 1994-01-19
JP2833949B2 (ja) 1998-12-09
NO924964L (no) 1993-06-28
TW211007B (hu) 1993-08-11
NO302471B1 (no) 1998-03-09
HUT67788A (en) 1995-04-28
HK196095A (en) 1996-01-05
CN1032751C (zh) 1996-09-11
ZA9210021B (en) 1993-07-02
GR3017632T3 (en) 1996-01-31
CA2086277A1 (en) 1993-06-27
CN1074680A (zh) 1993-07-28
MX9207595A (es) 1994-06-30

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Legal Events

Date Code Title Description
HMM4 Cancellation of final prot. due to non-payment of fee