HU230629B1 - Emlős citokin: interleukin-B30 és rokon molekulák - Google Patents

Emlős citokin: interleukin-B30 és rokon molekulák Download PDF

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Publication number
HU230629B1
HU230629B1 HU0004019A HUP0004019A HU230629B1 HU 230629 B1 HU230629 B1 HU 230629B1 HU 0004019 A HU0004019 A HU 0004019A HU P0004019 A HUP0004019 A HU P0004019A HU 230629 B1 HU230629 B1 HU 230629B1
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Hungary
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gin
asp
thr
ser
arg
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HU0004019A
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English (en)
Hungarian (hu)
Inventor
J. Fernando Bazan
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Merck Sharp & Dohme Corp
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Application filed by Merck Sharp & Dohme Corp filed Critical Merck Sharp & Dohme Corp
Publication of HUP0004019A2 publication Critical patent/HUP0004019A2/hu
Publication of HUP0004019A3 publication Critical patent/HUP0004019A3/hu
Publication of HU230629B1 publication Critical patent/HU230629B1/hu

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/54Interleukins [IL]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
HU0004019A 1997-07-25 1998-07-24 Emlős citokin: interleukin-B30 és rokon molekulák HU230629B1 (hu)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US90090597A 1997-07-25 1997-07-25
US08/900,905 1997-07-25
PCT/US1998/015423 WO1999005280A1 (en) 1997-07-25 1998-07-24 Mammalian cytokine: interleukin-b30 and related reagents

Publications (3)

Publication Number Publication Date
HUP0004019A2 HUP0004019A2 (en) 2001-03-28
HUP0004019A3 HUP0004019A3 (en) 2003-08-28
HU230629B1 true HU230629B1 (hu) 2017-04-28

Family

ID=25413278

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0004019A HU230629B1 (hu) 1997-07-25 1998-07-24 Emlős citokin: interleukin-B30 és rokon molekulák

Country Status (28)

Country Link
EP (3) EP2233574A1 (https=)
JP (5) JP4316133B2 (https=)
KR (1) KR100666835B1 (https=)
CN (2) CN101851286A (https=)
AR (2) AR017510A1 (https=)
AT (1) ATE443142T1 (https=)
AU (1) AU741046B2 (https=)
BR (1) BR9811039A (https=)
CA (1) CA2296272C (https=)
CO (1) CO4810232A1 (https=)
CZ (1) CZ300958B6 (https=)
DE (1) DE69841161D1 (https=)
DK (2) DK1002084T3 (https=)
ES (2) ES2610483T3 (https=)
HU (1) HU230629B1 (https=)
ID (1) ID28114A (https=)
IL (3) IL134068A0 (https=)
LT (1) LT2100959T (https=)
MY (1) MY157028A (https=)
NO (1) NO329329B1 (https=)
NZ (1) NZ502391A (https=)
PE (1) PE20000183A1 (https=)
PL (1) PL197150B1 (https=)
PT (2) PT2100959T (https=)
SK (1) SK287198B6 (https=)
TW (1) TWI237057B (https=)
WO (1) WO1999005280A1 (https=)
ZA (1) ZA986596B (https=)

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ATE329928T1 (de) * 1997-10-23 2006-07-15 Nippon Inst For Biolog Science Granulozyten-kolonie-stimulierender faktor aus der katze
WO1999040195A1 (en) * 1998-02-06 1999-08-12 Schering Corporation Mammalian receptor proteins; related reagents and methods
DE69942607D1 (de) 1998-04-14 2010-09-02 Chugai Pharmaceutical Co Ltd Neues cytokinartiges protein
AU2005202420B2 (en) * 1999-09-09 2008-08-07 Merck Sharp & Dohme Corp. Mammalian cytokines; related reagents and methods
AU780163B2 (en) * 1999-09-09 2005-03-03 Merck Sharp & Dohme Corp. Mammalian interleukin-12 P40 and interleukin B30, combinations thereof, antibodies, uses in pharmaceutical compositions
EP1905832A3 (en) 1999-09-09 2009-09-09 Schering Corporation Mammalian interleukin-12 P40 and interleukin B30, combinations thereof, antibodies, uses in pharmaceutical compositions
US7090847B1 (en) 1999-09-09 2006-08-15 Schering Corporation Mammalian cytokines; related reagents and methods
WO2004042009A2 (en) 2002-10-30 2004-05-21 Genentech, Inc. Inhibition of il-17 production
CN101052726A (zh) 2003-05-09 2007-10-10 森托科尔公司 IL-23p40特异性免疫球蛋白衍生蛋白、组合物、方法和用途
WO2005108425A1 (en) * 2004-05-10 2005-11-17 Cytos Biotechnology Ag Il-23 p19 antigen array and uses thereof
AR051444A1 (es) 2004-09-24 2007-01-17 Centocor Inc Proteinas derivadas de inmunoglobulina especifica de il-23p40, composiciones, epitopos, metodos y usos
SI2452694T1 (sl) 2005-06-30 2019-05-31 Janssen Biotech, Inc. Protitelesa proti-IL-23, sestavki in postopki uporabe
HUE034269T2 (en) 2005-12-29 2018-02-28 Janssen Biotech Inc Human anti-IL-23 antibodies, preparations, methods and applications
US7790862B2 (en) 2006-06-13 2010-09-07 Zymogenetics, Inc. IL-17 and IL-23 antagonists and methods of using the same
US7910703B2 (en) 2006-03-10 2011-03-22 Zymogenetics, Inc. Antagonists to IL-17A, IL-17F, and IL-23P19 and methods of use
TWI426918B (zh) 2007-02-12 2014-02-21 Merck Sharp & Dohme Il-23拮抗劑於治療感染之用途
EP2650311A3 (en) 2007-11-27 2014-06-04 Ablynx N.V. Amino acid sequences directed against heterodimeric cytokines and/or their receptors and polypeptides comprising the same
RU2474588C2 (ru) 2008-05-05 2013-02-10 Новиммун Са Перекрестно-реактивные антитела анти-il-17a/il-17f и способы их применения
CN102458437B (zh) 2009-05-05 2015-06-10 诺维莫尼公司 抗il-17f抗体及其使用方法
JO3244B1 (ar) 2009-10-26 2018-03-08 Amgen Inc بروتينات ربط مستضادات il – 23 البشرية
MX2019000046A (es) 2010-11-04 2023-10-05 Boehringer Ingelheim Int Anticuerpos anti-il-23.
PL3326649T3 (pl) 2012-05-03 2022-04-25 Boehringer Ingelheim International Gmbh Przeciwciała anty-il-23p19
SG11201507483PA (en) 2013-03-15 2015-10-29 Amgen Inc Methods for treating crohn's disease using an anti-il23 antibody
SG11201507482UA (en) 2013-03-15 2015-10-29 Amgen Inc Methods for treating psoriasis using an anti-il-23 antibody
EP3708679A1 (en) 2014-07-24 2020-09-16 Boehringer Ingelheim International GmbH Biomarkers useful in the treatment of il-23a related diseases
EA202193002A2 (ru) 2014-09-03 2022-03-31 Бёрингер Ингельхайм Интернациональ Гмбх Соединение, нацеленное на ил-23a и фно-альфа, и его применение
AU2016215535B2 (en) 2015-02-04 2021-09-16 Boehringer Ingelheim International Gmbh Methods of treating inflammatory diseases
CN108290058B (zh) 2015-09-17 2023-05-16 美国安进公司 使用il23途径生物标志物预测il23拮抗剂的临床应答
US11220541B2 (en) 2015-12-22 2022-01-11 Amgen Inc. CCL20 as a predictor of clinical response to IL23-antagonists
CN112689643A (zh) 2018-07-13 2021-04-20 阿斯特捷利康合作创业有限责任公司 用布雷库单抗治疗溃疡性结肠炎
IL283192B2 (en) 2018-11-20 2025-10-01 Janssen Biotech Inc A safe and effective method for treating psoriasis with a specific anti-IL-23 antibody
JP7805788B2 (ja) 2019-05-23 2026-01-26 ヤンセン バイオテツク,インコーポレーテツド Il-23及びtnfアルファに対する抗体の併用療法による炎症性腸疾患の治療方法
TW202535466A (zh) 2019-09-09 2025-09-16 德商百靈佳殷格翰國際股份有限公司 抗-il-23p19抗體調配物
JP7758672B2 (ja) 2019-12-20 2025-10-22 ノヴァロック バイオセラピューティクス, リミテッド 抗インターロイキン-23 p19抗体およびそれの使用方法
IL298389A (en) 2020-05-21 2023-01-01 Janssen Biotech Inc Method of treating inflammatory bowel disease with a combination therapy of antibodies to il-23 and tnf alpha

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FR2046920B1 (https=) 1969-06-19 1974-05-03 Citizen Watch Co Ltd
US3940475A (en) 1970-06-11 1976-02-24 Biological Developments, Inc. Radioimmune method of assaying quantitatively for a hapten
NL154598B (nl) 1970-11-10 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking.
US3817837A (en) 1971-05-14 1974-06-18 Syva Corp Enzyme amplification assay
US3939350A (en) 1974-04-29 1976-02-17 Board Of Trustees Of The Leland Stanford Junior University Fluorescent immunoassay employing total reflection for activation
US3996345A (en) 1974-08-12 1976-12-07 Syva Company Fluorescence quenching with immunological pairs in immunoassays
US4275149A (en) 1978-11-24 1981-06-23 Syva Company Macromolecular environment control in specific receptor assays
US4277437A (en) 1978-04-05 1981-07-07 Syva Company Kit for carrying out chemically induced fluorescence immunoassay
US4366241A (en) 1980-08-07 1982-12-28 Syva Company Concentrating zone method in heterogeneous immunoassays
DE3382317D1 (de) 1982-03-15 1991-07-25 Schering Corp Hybride dns, damit hergestellte bindungszusammensetzung und verfahren dafuer.
US4659678A (en) 1982-09-29 1987-04-21 Serono Diagnostics Limited Immunoassay of antigens
NZ207394A (en) 1983-03-08 1987-03-06 Commw Serum Lab Commission Detecting or determining sequence of amino acids
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US4859609A (en) 1986-04-30 1989-08-22 Genentech, Inc. Novel receptors for efficient determination of ligands and their antagonists or agonists
US5891680A (en) * 1995-02-08 1999-04-06 Whitehead Institute For Biomedical Research Bioactive fusion proteins comprising the p35 and p40 subunits of IL-12
DE69942607D1 (de) * 1998-04-14 2010-09-02 Chugai Pharmaceutical Co Ltd Neues cytokinartiges protein

Also Published As

Publication number Publication date
NO20000343D0 (no) 2000-01-24
AR086483A2 (es) 2013-12-18
JP2015037405A (ja) 2015-02-26
EP2100959B1 (en) 2016-12-07
CA2296272C (en) 2012-03-13
PL197150B1 (pl) 2008-03-31
JP4316133B2 (ja) 2009-08-19
BR9811039A (pt) 2000-08-08
LT2100959T (lt) 2017-01-10
SK287198B6 (sk) 2010-03-08
TWI237057B (en) 2005-08-01
JP2010011863A (ja) 2010-01-21
IL134068A0 (en) 2001-04-30
CN101851286A (zh) 2010-10-06
KR20010022214A (ko) 2001-03-15
NO329329B1 (no) 2010-09-27
NZ502391A (en) 2002-12-20
JP2001511347A (ja) 2001-08-14
AR017510A1 (es) 2001-09-12
IL134068A (en) 2010-11-30
WO1999005280A1 (en) 1999-02-04
CA2296272A1 (en) 1999-02-04
IL205765A0 (en) 2011-07-31
EP2100959A2 (en) 2009-09-16
EP2233574A1 (en) 2010-09-29
EP1002084A1 (en) 2000-05-24
DK1002084T3 (da) 2010-01-04
AU741046B2 (en) 2001-11-22
PL338262A1 (en) 2000-10-09
IL205765A (en) 2015-07-30
JP2013034480A (ja) 2013-02-21
ATE443142T1 (de) 2009-10-15
ZA986596B (en) 1999-02-08
DK2100959T3 (en) 2017-01-30
HUP0004019A3 (en) 2003-08-28
SK912000A3 (en) 2000-09-12
ES2331762T3 (es) 2010-01-14
MY157028A (en) 2016-04-15
PT1002084E (pt) 2009-12-16
ID28114A (id) 2001-05-03
HK1024932A1 (en) 2000-10-27
CZ2000263A3 (cs) 2000-06-14
CN1271387A (zh) 2000-10-25
HUP0004019A2 (en) 2001-03-28
PT2100959T (pt) 2017-01-09
PE20000183A1 (es) 2000-03-11
EP2100959A3 (en) 2009-10-14
CZ300958B6 (cs) 2009-09-23
CO4810232A1 (es) 1999-06-30
AU8589498A (en) 1999-02-16
DE69841161D1 (de) 2009-10-29
EP1002084B1 (en) 2009-09-16
JP2005323610A (ja) 2005-11-24
ES2610483T3 (es) 2017-04-27
NO20000343L (no) 2000-03-24
KR100666835B1 (ko) 2007-01-11

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Legal Events

Date Code Title Description
FH91 Appointment of a representative

Free format text: FORMER REPRESENTATIVE(S): RATHONYI ZOLTAN, S.B.G. & K. SZABADALMI UEGYVIVOEI IRODA, HU

Representative=s name: RATHONYI ZOLTAN, S.B.G. & K., SZABADALMI UEGYV, HU

HC9A Change of name, address

Owner name: MERCK SHARP & DOHME CORP., US

Free format text: FORMER OWNER(S): SCHERING CORP., US