ES2610483T3 - Citocina de mamífero: interleucina-B30 y agentes relacionados - Google Patents

Citocina de mamífero: interleucina-B30 y agentes relacionados Download PDF

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Publication number
ES2610483T3
ES2610483T3 ES09156327.0T ES09156327T ES2610483T3 ES 2610483 T3 ES2610483 T3 ES 2610483T3 ES 09156327 T ES09156327 T ES 09156327T ES 2610483 T3 ES2610483 T3 ES 2610483T3
Authority
ES
Spain
Prior art keywords
cells
hours
activated
grouped
sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES09156327.0T
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English (en)
Spanish (es)
Inventor
J. Fernando Bazan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Organon Pharma UK Ltd
Merck Sharp and Dohme LLC
Original Assignee
Merck Sharp and Dohme Ltd
Merck Sharp and Dohme LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25413278&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2610483(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merck Sharp and Dohme Ltd, Merck Sharp and Dohme LLC filed Critical Merck Sharp and Dohme Ltd
Application granted granted Critical
Publication of ES2610483T3 publication Critical patent/ES2610483T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
ES09156327.0T 1997-07-25 1998-07-24 Citocina de mamífero: interleucina-B30 y agentes relacionados Expired - Lifetime ES2610483T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US90090597A 1997-07-25 1997-07-25
US900905 1997-07-25

Publications (1)

Publication Number Publication Date
ES2610483T3 true ES2610483T3 (es) 2017-04-27

Family

ID=25413278

Family Applications (2)

Application Number Title Priority Date Filing Date
ES09156327.0T Expired - Lifetime ES2610483T3 (es) 1997-07-25 1998-07-24 Citocina de mamífero: interleucina-B30 y agentes relacionados
ES98937105T Expired - Lifetime ES2331762T3 (es) 1997-07-25 1998-07-24 Citoquina de mamifero: interleuquina-b30 y reactivos correspondientes.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES98937105T Expired - Lifetime ES2331762T3 (es) 1997-07-25 1998-07-24 Citoquina de mamifero: interleuquina-b30 y reactivos correspondientes.

Country Status (28)

Country Link
EP (3) EP2233574A1 (https=)
JP (5) JP4316133B2 (https=)
KR (1) KR100666835B1 (https=)
CN (2) CN101851286A (https=)
AR (2) AR017510A1 (https=)
AT (1) ATE443142T1 (https=)
AU (1) AU741046B2 (https=)
BR (1) BR9811039A (https=)
CA (1) CA2296272C (https=)
CO (1) CO4810232A1 (https=)
CZ (1) CZ300958B6 (https=)
DE (1) DE69841161D1 (https=)
DK (2) DK1002084T3 (https=)
ES (2) ES2610483T3 (https=)
HU (1) HU230629B1 (https=)
ID (1) ID28114A (https=)
IL (3) IL134068A0 (https=)
LT (1) LT2100959T (https=)
MY (1) MY157028A (https=)
NO (1) NO329329B1 (https=)
NZ (1) NZ502391A (https=)
PE (1) PE20000183A1 (https=)
PL (1) PL197150B1 (https=)
PT (2) PT2100959T (https=)
SK (1) SK287198B6 (https=)
TW (1) TWI237057B (https=)
WO (1) WO1999005280A1 (https=)
ZA (1) ZA986596B (https=)

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US6060284A (en) 1997-07-25 2000-05-09 Schering Corporation DNA encoding interleukin-B30
ATE329928T1 (de) * 1997-10-23 2006-07-15 Nippon Inst For Biolog Science Granulozyten-kolonie-stimulierender faktor aus der katze
WO1999040195A1 (en) * 1998-02-06 1999-08-12 Schering Corporation Mammalian receptor proteins; related reagents and methods
DE69942607D1 (de) 1998-04-14 2010-09-02 Chugai Pharmaceutical Co Ltd Neues cytokinartiges protein
AU2005202420B2 (en) * 1999-09-09 2008-08-07 Merck Sharp & Dohme Corp. Mammalian cytokines; related reagents and methods
AU780163B2 (en) * 1999-09-09 2005-03-03 Merck Sharp & Dohme Corp. Mammalian interleukin-12 P40 and interleukin B30, combinations thereof, antibodies, uses in pharmaceutical compositions
EP1905832A3 (en) 1999-09-09 2009-09-09 Schering Corporation Mammalian interleukin-12 P40 and interleukin B30, combinations thereof, antibodies, uses in pharmaceutical compositions
US7090847B1 (en) 1999-09-09 2006-08-15 Schering Corporation Mammalian cytokines; related reagents and methods
WO2004042009A2 (en) 2002-10-30 2004-05-21 Genentech, Inc. Inhibition of il-17 production
CN101052726A (zh) 2003-05-09 2007-10-10 森托科尔公司 IL－23p40特异性免疫球蛋白衍生蛋白、组合物、方法和用途
WO2005108425A1 (en) * 2004-05-10 2005-11-17 Cytos Biotechnology Ag Il-23 p19 antigen array and uses thereof
AR051444A1 (es) 2004-09-24 2007-01-17 Centocor Inc Proteinas derivadas de inmunoglobulina especifica de il-23p40, composiciones, epitopos, metodos y usos
SI2452694T1 (sl) 2005-06-30 2019-05-31 Janssen Biotech, Inc. Protitelesa proti-IL-23, sestavki in postopki uporabe
HUE034269T2 (en) 2005-12-29 2018-02-28 Janssen Biotech Inc Human anti-IL-23 antibodies, preparations, methods and applications
US7790862B2 (en) 2006-06-13 2010-09-07 Zymogenetics, Inc. IL-17 and IL-23 antagonists and methods of using the same
US7910703B2 (en) 2006-03-10 2011-03-22 Zymogenetics, Inc. Antagonists to IL-17A, IL-17F, and IL-23P19 and methods of use
TWI426918B (zh) 2007-02-12 2014-02-21 Merck Sharp & Dohme Ｉｌ-２３拮抗劑於治療感染之用途
EP2650311A3 (en) 2007-11-27 2014-06-04 Ablynx N.V. Amino acid sequences directed against heterodimeric cytokines and/or their receptors and polypeptides comprising the same
RU2474588C2 (ru) 2008-05-05 2013-02-10 Новиммун Са Перекрестно-реактивные антитела анти-il-17a/il-17f и способы их применения
CN102458437B (zh) 2009-05-05 2015-06-10 诺维莫尼公司 抗il-17f抗体及其使用方法
JO3244B1 (ar) 2009-10-26 2018-03-08 Amgen Inc بروتينات ربط مستضادات il – 23 البشرية
MX2019000046A (es) 2010-11-04 2023-10-05 Boehringer Ingelheim Int Anticuerpos anti-il-23.
PL3326649T3 (pl) 2012-05-03 2022-04-25 Boehringer Ingelheim International Gmbh Przeciwciała anty-il-23p19
SG11201507483PA (en) 2013-03-15 2015-10-29 Amgen Inc Methods for treating crohn's disease using an anti-il23 antibody
SG11201507482UA (en) 2013-03-15 2015-10-29 Amgen Inc Methods for treating psoriasis using an anti-il-23 antibody
EP3708679A1 (en) 2014-07-24 2020-09-16 Boehringer Ingelheim International GmbH Biomarkers useful in the treatment of il-23a related diseases
EA202193002A2 (ru) 2014-09-03 2022-03-31 Бёрингер Ингельхайм Интернациональ Гмбх Соединение, нацеленное на ил-23a и фно-альфа, и его применение
AU2016215535B2 (en) 2015-02-04 2021-09-16 Boehringer Ingelheim International Gmbh Methods of treating inflammatory diseases
CN108290058B (zh) 2015-09-17 2023-05-16 美国安进公司 使用il23途径生物标志物预测il23拮抗剂的临床应答
US11220541B2 (en) 2015-12-22 2022-01-11 Amgen Inc. CCL20 as a predictor of clinical response to IL23-antagonists
CN112689643A (zh) 2018-07-13 2021-04-20 阿斯特捷利康合作创业有限责任公司 用布雷库单抗治疗溃疡性结肠炎
IL283192B2 (en) 2018-11-20 2025-10-01 Janssen Biotech Inc A safe and effective method for treating psoriasis with a specific anti-IL-23 antibody
JP7805788B2 (ja) 2019-05-23 2026-01-26 ヤンセン バイオテツク，インコーポレーテツド Ｉｌ－２３及びｔｎｆアルファに対する抗体の併用療法による炎症性腸疾患の治療方法
TW202535466A (zh) 2019-09-09 2025-09-16 德商百靈佳殷格翰國際股份有限公司 抗-il-23p19抗體調配物
JP7758672B2 (ja) 2019-12-20 2025-10-22 ノヴァロック バイオセラピューティクス， リミテッド 抗インターロイキン－２３ ｐ１９抗体およびそれの使用方法
IL298389A (en) 2020-05-21 2023-01-01 Janssen Biotech Inc Method of treating inflammatory bowel disease with a combination therapy of antibodies to il-23 and tnf alpha

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FR2046920B1 (https=) 1969-06-19 1974-05-03 Citizen Watch Co Ltd
US3940475A (en) 1970-06-11 1976-02-24 Biological Developments, Inc. Radioimmune method of assaying quantitatively for a hapten
NL154598B (nl) 1970-11-10 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking.
US3817837A (en) 1971-05-14 1974-06-18 Syva Corp Enzyme amplification assay
US3939350A (en) 1974-04-29 1976-02-17 Board Of Trustees Of The Leland Stanford Junior University Fluorescent immunoassay employing total reflection for activation
US3996345A (en) 1974-08-12 1976-12-07 Syva Company Fluorescence quenching with immunological pairs in immunoassays
US4275149A (en) 1978-11-24 1981-06-23 Syva Company Macromolecular environment control in specific receptor assays
US4277437A (en) 1978-04-05 1981-07-07 Syva Company Kit for carrying out chemically induced fluorescence immunoassay
US4366241A (en) 1980-08-07 1982-12-28 Syva Company Concentrating zone method in heterogeneous immunoassays
DE3382317D1 (de) 1982-03-15 1991-07-25 Schering Corp Hybride dns, damit hergestellte bindungszusammensetzung und verfahren dafuer.
US4659678A (en) 1982-09-29 1987-04-21 Serono Diagnostics Limited Immunoassay of antigens
NZ207394A (en) 1983-03-08 1987-03-06 Commw Serum Lab Commission Detecting or determining sequence of amino acids
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US4859609A (en) 1986-04-30 1989-08-22 Genentech, Inc. Novel receptors for efficient determination of ligands and their antagonists or agonists
US5891680A (en) * 1995-02-08 1999-04-06 Whitehead Institute For Biomedical Research Bioactive fusion proteins comprising the p35 and p40 subunits of IL-12
DE69942607D1 (de) * 1998-04-14 2010-09-02 Chugai Pharmaceutical Co Ltd Neues cytokinartiges protein

Also Published As

Publication number Publication date
NO20000343D0 (no) 2000-01-24
AR086483A2 (es) 2013-12-18
JP2015037405A (ja) 2015-02-26
EP2100959B1 (en) 2016-12-07
CA2296272C (en) 2012-03-13
PL197150B1 (pl) 2008-03-31
JP4316133B2 (ja) 2009-08-19
BR9811039A (pt) 2000-08-08
LT2100959T (lt) 2017-01-10
SK287198B6 (sk) 2010-03-08
TWI237057B (en) 2005-08-01
JP2010011863A (ja) 2010-01-21
IL134068A0 (en) 2001-04-30
CN101851286A (zh) 2010-10-06
KR20010022214A (ko) 2001-03-15
NO329329B1 (no) 2010-09-27
NZ502391A (en) 2002-12-20
JP2001511347A (ja) 2001-08-14
AR017510A1 (es) 2001-09-12
IL134068A (en) 2010-11-30
WO1999005280A1 (en) 1999-02-04
CA2296272A1 (en) 1999-02-04
IL205765A0 (en) 2011-07-31
EP2100959A2 (en) 2009-09-16
EP2233574A1 (en) 2010-09-29
EP1002084A1 (en) 2000-05-24
DK1002084T3 (da) 2010-01-04
AU741046B2 (en) 2001-11-22
PL338262A1 (en) 2000-10-09
IL205765A (en) 2015-07-30
JP2013034480A (ja) 2013-02-21
ATE443142T1 (de) 2009-10-15
ZA986596B (en) 1999-02-08
DK2100959T3 (en) 2017-01-30
HUP0004019A3 (en) 2003-08-28
SK912000A3 (en) 2000-09-12
ES2331762T3 (es) 2010-01-14
MY157028A (en) 2016-04-15
PT1002084E (pt) 2009-12-16
ID28114A (id) 2001-05-03
HK1024932A1 (en) 2000-10-27
CZ2000263A3 (cs) 2000-06-14
CN1271387A (zh) 2000-10-25
HU230629B1 (hu) 2017-04-28
HUP0004019A2 (en) 2001-03-28
PT2100959T (pt) 2017-01-09
PE20000183A1 (es) 2000-03-11
EP2100959A3 (en) 2009-10-14
CZ300958B6 (cs) 2009-09-23
CO4810232A1 (es) 1999-06-30
AU8589498A (en) 1999-02-16
DE69841161D1 (de) 2009-10-29
EP1002084B1 (en) 2009-09-16
JP2005323610A (ja) 2005-11-24
NO20000343L (no) 2000-03-24
KR100666835B1 (ko) 2007-01-11

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