HU230582B1 - IL-13 és IL-13-receptorláncok antagonizmusának alkalmazása fibrózis kezelésére - Google Patents

IL-13 és IL-13-receptorláncok antagonizmusának alkalmazása fibrózis kezelésére Download PDF

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Publication number
HU230582B1
HU230582B1 HU0200862A HUP0200862A HU230582B1 HU 230582 B1 HU230582 B1 HU 230582B1 HU 0200862 A HU0200862 A HU 0200862A HU P0200862 A HUP0200862 A HU P0200862A HU 230582 B1 HU230582 B1 HU 230582B1
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amino acid
composition
tissue
acid sequence
seq
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HU0200862A
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English (en)
Hungarian (hu)
Inventor
Thomas A. Wynn
Monica G. Chiaramonte
Mary Collins
Debra Donaldson
Lori Fitz
Tamlyn Neben
Matthew J. Whitters
Clive Wood
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Genetics Institute Inc.
The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services
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Application filed by Genetics Institute Inc., The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services filed Critical Genetics Institute Inc.
Publication of HUP0200862A2 publication Critical patent/HUP0200862A2/hu
Publication of HUP0200862A3 publication Critical patent/HUP0200862A3/hu
Publication of HU230582B1 publication Critical patent/HU230582B1/hu

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    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7155Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
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    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/04Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/38Drugs for disorders of the endocrine system of the suprarenal hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
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    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
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  • General Chemical & Material Sciences (AREA)
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  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
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  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Reproductive Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Diabetes (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Dermatology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
HU0200862A 1999-04-28 2000-04-28 IL-13 és IL-13-receptorláncok antagonizmusának alkalmazása fibrózis kezelésére HU230582B1 (hu)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/301,808 US6664227B1 (en) 1996-03-01 1999-04-28 Treatment of fibrosis by antagonism of IL-13 and IL-13 receptor chains
US09/301,808 1999-04-28
PCT/US2000/011612 WO2000064944A1 (en) 1999-04-28 2000-04-28 Treatment of fibrosis by antagonism of il-13 and il-13 receptor chains

Publications (3)

Publication Number Publication Date
HUP0200862A2 HUP0200862A2 (hu) 2002-07-29
HUP0200862A3 HUP0200862A3 (en) 2004-11-29
HU230582B1 true HU230582B1 (hu) 2017-01-30

Family

ID=23164976

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0200862A HU230582B1 (hu) 1999-04-28 2000-04-28 IL-13 és IL-13-receptorláncok antagonizmusának alkalmazása fibrózis kezelésére

Country Status (16)

Country Link
US (2) US6664227B1 (de)
EP (2) EP2123674A1 (de)
JP (3) JP4988988B2 (de)
KR (1) KR100862931B1 (de)
CN (1) CN1348465A (de)
AT (1) ATE515513T1 (de)
AU (1) AU780991B2 (de)
BR (1) BR0010061A (de)
CA (1) CA2370306C (de)
DK (1) DK1173484T3 (de)
HU (1) HU230582B1 (de)
IL (2) IL146082A0 (de)
MX (1) MXPA01011023A (de)
NZ (1) NZ515464A (de)
PT (1) PT1173484E (de)
WO (1) WO2000064944A1 (de)

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EP2273419B1 (de) 2002-06-14 2012-03-14 GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES Verfahren zur Behandlung und Prävention von Kolitis, die IL-13 und NK-T Zellen betrifft
US20070104710A1 (en) * 2002-06-28 2007-05-10 Domants Limited Ligand that has binding specificity for IL-4 and/or IL-13
US20110223168A1 (en) * 2002-12-27 2011-09-15 Greg Winter Ligand that has binding specificity for il-4 and/or il-13
EP1444989A1 (de) * 2003-02-07 2004-08-11 Giorgio Dr. Stassi Sensibilisierung von Zellen für die Apoptose durch selektive Blockade von Zytokinen
GB0407315D0 (en) 2003-07-15 2004-05-05 Cambridge Antibody Tech Human antibody molecules
AU2004308494B2 (en) * 2003-12-23 2010-03-18 Genentech, Inc. Novel anti-IL 13 antibodies and uses thereof
EP1713441A2 (de) * 2004-02-12 2006-10-25 Nektar Therapeutics Interleukin-13-antagonist-pulver, sprühgetrocknete partikel und verfahren
PT1734970E (pt) 2004-03-12 2015-03-11 Intercept Pharmaceuticals Inc Tratamento de fibrose utilizando ligandos de rfx
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US7501121B2 (en) * 2004-06-17 2009-03-10 Wyeth IL-13 binding agents
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EP1824886B1 (de) 2004-11-17 2010-12-22 Amgen Inc. Vollständige humane monoklonale antikörper gegen il-13
JP4465469B2 (ja) * 2005-02-21 2010-05-19 国立大学法人佐賀大学 循環器病マーカーとしてのインターロイキン13
US20080044420A1 (en) * 2005-05-11 2008-02-21 Heavner George A Anti-IL-13 antibodies, compositions, methods and uses
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EP2532677A1 (de) 2005-10-21 2012-12-12 Novartis AG Menschliche Antikörper gegen IL13 und therapeutische Verwendungen
CN101529253A (zh) * 2006-06-21 2009-09-09 阿珀吉尼科斯有限公司 Il-4和/或il-10细胞因子在人癌症中的差异表达
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WO2008076784A2 (en) * 2006-12-15 2008-06-26 Centocor Ortho Biotech Inc. Methods and compositions for treating il-4 or il-13 related fibrosis related pathologies
CN101977935A (zh) * 2007-04-23 2011-02-16 惠氏公司 用于治疗和监测il-13相关病症的方法和组合物
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Also Published As

Publication number Publication date
US20050096268A1 (en) 2005-05-05
KR100862931B1 (ko) 2008-10-13
JP2014087345A (ja) 2014-05-15
CA2370306C (en) 2014-06-17
ATE515513T1 (de) 2011-07-15
IL146082A (en) 2014-08-31
EP2123674A1 (de) 2009-11-25
CA2370306A1 (en) 2000-11-02
EP1173484A1 (de) 2002-01-23
HUP0200862A2 (hu) 2002-07-29
JP4988988B2 (ja) 2012-08-01
EP1173484A4 (de) 2003-05-21
PT1173484E (pt) 2011-09-29
AU4680500A (en) 2000-11-10
CN1348465A (zh) 2002-05-08
BR0010061A (pt) 2003-02-25
HUP0200862A3 (en) 2004-11-29
US6664227B1 (en) 2003-12-16
IL146082A0 (en) 2002-07-25
JP2003527311A (ja) 2003-09-16
KR20020026426A (ko) 2002-04-10
EP1173484B1 (de) 2011-07-06
NZ515464A (en) 2004-02-27
DK1173484T3 (da) 2011-10-03
AU780991B2 (en) 2005-04-28
US7282206B2 (en) 2007-10-16
MXPA01011023A (es) 2002-05-06
JP2011078432A (ja) 2011-04-21
WO2000064944A1 (en) 2000-11-02

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