HU222810B1 - Interleukin-1 inhibitorok, ezeket kódoló DNS-szekvenciák, a szekvenciákat tartalmazó rekombináns DNS-vektorok, a vektort tartalmazó gazdasejtek és rekombináns GT-10-il-1i-2A DNS molekula - Google Patents

Interleukin-1 inhibitorok, ezeket kódoló DNS-szekvenciák, a szekvenciákat tartalmazó rekombináns DNS-vektorok, a vektort tartalmazó gazdasejtek és rekombináns GT-10-il-1i-2A DNS molekula Download PDF

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Publication number
HU222810B1
HU222810B1 HU9803037A HU9803037A HU222810B1 HU 222810 B1 HU222810 B1 HU 222810B1 HU 9803037 A HU9803037 A HU 9803037A HU 9803037 A HU9803037 A HU 9803037A HU 222810 B1 HU222810 B1 HU 222810B1
Authority
HU
Hungary
Prior art keywords
sequence
amino acid
polypeptide
acid sequence
host cell
Prior art date
Application number
HU9803037A
Other languages
English (en)
Hungarian (hu)
Inventor
William P. Arend
Stephen P. Eisenberg
Charles H. Hannum
Fenneke G. Joslin
Andreas Sommer
Robert C. Thompson
Original Assignee
Synergen Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synergen Inc. filed Critical Synergen Inc.
Publication of HU222810B1 publication Critical patent/HU222810B1/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Rheumatology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Transplantation (AREA)
  • Toxicology (AREA)
  • Pain & Pain Management (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HU9803037A 1988-05-27 1989-05-25 Interleukin-1 inhibitorok, ezeket kódoló DNS-szekvenciák, a szekvenciákat tartalmazó rekombináns DNS-vektorok, a vektort tartalmazó gazdasejtek és rekombináns GT-10-il-1i-2A DNS molekula HU222810B1 (hu)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US19991588A 1988-05-27 1988-05-27
US23871388A 1988-08-31 1988-08-31
US26653188A 1988-11-03 1988-11-03
PCT/US1989/002275 WO1989011540A1 (en) 1988-05-27 1989-05-25 Interleukin-1 inhibitors

Publications (1)

Publication Number Publication Date
HU222810B1 true HU222810B1 (hu) 2003-11-28

Family

ID=27394086

Family Applications (3)

Application Number Title Priority Date Filing Date
HU9803037A HU9803037D0 (en) 1988-05-27 1989-05-25 Interleukin-1 inhibitors
HU9803037A HU222810B1 (hu) 1988-05-27 1989-05-25 Interleukin-1 inhibitorok, ezeket kódoló DNS-szekvenciák, a szekvenciákat tartalmazó rekombináns DNS-vektorok, a vektort tartalmazó gazdasejtek és rekombináns GT-10-il-1i-2A DNS molekula
HU3412/89A HU215434B (hu) 1988-05-27 1989-05-25 Eljárás interleukin-1 inhibitorok, ezeket kódoló DNS-szekvenciák, vektorok és gazdasejtek előállítására

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HU9803037A HU9803037D0 (en) 1988-05-27 1989-05-25 Interleukin-1 inhibitors

Family Applications After (1)

Application Number Title Priority Date Filing Date
HU3412/89A HU215434B (hu) 1988-05-27 1989-05-25 Eljárás interleukin-1 inhibitorok, ezeket kódoló DNS-szekvenciák, vektorok és gazdasejtek előállítására

Country Status (9)

Country Link
JP (2) JP3192651B2 (fi)
KR (1) KR970002917B1 (fi)
BR (1) BR8907457A (fi)
DK (1) DK172763B1 (fi)
FI (2) FI109206B (fi)
HU (3) HU9803037D0 (fi)
NO (2) NO316122B1 (fi)
OA (1) OA09631A (fi)
WO (1) WO1989011540A1 (fi)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6858409B1 (en) 1988-05-27 2005-02-22 Amgen Inc. Nucleic acids encoding interleukin-1 inhibitors and processes for preparing interleukin-1 inhibitors
US6159460A (en) * 1988-05-27 2000-12-12 Amgen Inc. Method for treating interleukin-1 mediated diseases
US5075222A (en) 1988-05-27 1991-12-24 Synergen, Inc. Interleukin-1 inhibitors
ATE178094T1 (de) * 1990-05-01 1999-04-15 Chiron Corp Interleukin-i antagonist und seine verwendung
US5872095A (en) * 1990-05-01 1999-02-16 Chiron Corporation IL-1 receptor antagonists medicaments
US5747444A (en) * 1990-10-09 1998-05-05 Chiron Corporation Method of treating graft-versus-host disease
US5932537A (en) * 1990-10-09 1999-08-03 Chiron Corporation Method for attenuating a cellular response to IL-1
US6294170B1 (en) 1997-08-08 2001-09-25 Amgen Inc. Composition and method for treating inflammatory diseases
US20030103978A1 (en) 2000-02-23 2003-06-05 Amgen Inc. Selective binding agents of osteoprotegerin binding protein
US20060067938A1 (en) * 2001-10-26 2006-03-30 Sherif Daouti Methods for the treatment of osteoarthritis and compositions thereof
JP4761710B2 (ja) 2002-04-05 2011-08-31 アムジェン インコーポレイテッド 選択的ｏｐｇｌ経路インヒビターとしてのヒト抗ｏｐｇｌ中和抗体
EP2336177A1 (en) 2004-08-04 2011-06-22 Amgen, Inc Antibodies to DKK-1
WO2009026303A1 (en) 2007-08-21 2009-02-26 Amgen Inc. Human c-fms antigen binding proteins
CN102209557A (zh) * 2008-09-12 2011-10-05 埃克斯生物科技公司 靶向病原性单核细胞
WO2012025910A1 (en) 2010-08-26 2012-03-01 Centro De Investigación Y De Estudios Avanzados Del Instituto Politécnico Nacional METHODS OF DIAGNOSIS AND TREATMENT OF OSTEOARTHRITIS AT EARLY STAGES USING INTERLEUKIN IL-1ß AS EARLY BIOMARKER OF THE DISEASE
US9359405B2 (en) 2011-03-14 2016-06-07 Phlogo Aps Antagonists of the interleukin-1 receptor
AU2012242666A1 (en) 2011-04-15 2013-11-28 Merck Patent Gmbh Anti- IL-1R1 inhibitors for use in cancer
TW201605896A (zh) 2013-08-30 2016-02-16 安美基股份有限公司 Gitr抗原結合蛋白
WO2015087187A1 (en) 2013-12-10 2015-06-18 Rinat Neuroscience Corp. Anti-sclerostin antibodies
KR102380150B1 (ko) 2016-03-08 2022-03-29 얀센 바이오테크 인코포레이티드 Gitr 항체, 방법, 및 용도

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3014099B2 (ja) * 1987-08-26 2000-02-28 バイオジェン インコーポレイテッド 生物的材料、生物的材料の生産およびこの種の材料の治療への使用方法

Also Published As

Publication number Publication date
OA09631A (en) 1993-04-30
NO905090L (no) 1991-01-28
NO905090D0 (no) 1990-11-23
DK8591D0 (da) 1991-01-18
JP2001029093A (ja) 2001-02-06
AU633831B2 (en) 1993-02-11
DK172763B1 (da) 1999-07-05
WO1989011540A1 (en) 1989-11-30
NO20014783D0 (no) 2001-10-01
JPH03505279A (ja) 1991-11-21
NO20014783L (no) 1991-01-28
NO316122B1 (no) 2003-12-15
BR8907457A (pt) 1991-04-02
FI905812A0 (fi) 1990-11-26
FI109206B (fi) 2002-06-14
DK8591A (da) 1991-01-18
NO316917B1 (no) 2004-06-21
HU893412D0 (en) 1991-05-28
HU9803037D0 (en) 1999-11-29
JP3192651B2 (ja) 2001-07-30
AU3746989A (en) 1989-12-12
HU215434B (hu) 1999-04-28
FI20020545A (fi) 2002-03-21
KR970002917B1 (ko) 1997-03-12

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Legal Events

Date Code Title Description
HFG4 Patent granted, date of granting

Effective date: 20030929

HPC4 Succession in title of patentee

Owner name: AMGEN INC., US

FG4S Grant of supplementary protection certificate

Free format text: PRODUCT NAME: ANAKINRA; REGISTRATION NO/DATE: EU/1/02/203/001-004 20020308

Spc suppl protection certif: S0400030

Filing date: 20041012

Expiry date: 20090525

Extension date: 20140525