HU205711B - Process for producing pharmaceutical compositions with slow release, having polyester carrier containing alkylene oxide blocks, and for producing the carrier - Google Patents

Process for producing pharmaceutical compositions with slow release, having polyester carrier containing alkylene oxide blocks, and for producing the carrier Download PDF

Info

Publication number
HU205711B
HU205711B HU873970A HU397087A HU205711B HU 205711 B HU205711 B HU 205711B HU 873970 A HU873970 A HU 873970A HU 397087 A HU397087 A HU 397087A HU 205711 B HU205711 B HU 205711B
Authority
HU
Hungary
Prior art keywords
polymer
block
copolymer
gly
peo
Prior art date
Application number
HU873970A
Other languages
English (en)
Hungarian (hu)
Other versions
HUT52945A (en
Inventor
Donald James Casey
Peter Kendrick Jarrett
Louis Rosati
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/903,801 external-priority patent/US4882168A/en
Priority claimed from US06/903,797 external-priority patent/US4716203A/en
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of HUT52945A publication Critical patent/HUT52945A/hu
Publication of HU205711B publication Critical patent/HU205711B/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/64Polyesters containing both carboxylic ester groups and carbonate groups
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/2031Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A61K9/204Polyesters, e.g. poly(lactide-co-glycolide)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Materials For Medical Uses (AREA)
HU873970A 1986-09-05 1987-09-04 Process for producing pharmaceutical compositions with slow release, having polyester carrier containing alkylene oxide blocks, and for producing the carrier HU205711B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/903,801 US4882168A (en) 1986-09-05 1986-09-05 Polyesters containing alkylene oxide blocks as drug delivery systems
US06/903,797 US4716203A (en) 1986-09-05 1986-09-05 Diblock and triblock copolymers

Publications (2)

Publication Number Publication Date
HUT52945A HUT52945A (en) 1990-09-28
HU205711B true HU205711B (en) 1992-06-29

Family

ID=27129378

Family Applications (1)

Application Number Title Priority Date Filing Date
HU873970A HU205711B (en) 1986-09-05 1987-09-04 Process for producing pharmaceutical compositions with slow release, having polyester carrier containing alkylene oxide blocks, and for producing the carrier

Country Status (13)

Country Link
EP (1) EP0258780B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
KR (1) KR880003985A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU605172B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BR (1) BR8704648A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA1283988C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE3786309T2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK462287A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES2058081T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FI (1) FI873840L (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GR (1) GR3008526T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HU (1) HU205711B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IL (1) IL83764A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NZ (1) NZ221647A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL9401703A (nl) * 1994-10-14 1996-05-01 Rijksuniversiteit Kauwgom.
US5702717A (en) * 1995-10-25 1997-12-30 Macromed, Inc. Thermosensitive biodegradable polymers based on poly(ether-ester)block copolymers
US5665428A (en) * 1995-10-25 1997-09-09 Macromed, Inc. Preparation of peptide containing biodegradable microspheres by melt process
DE19726412A1 (de) * 1997-06-21 1998-12-24 Merck Patent Gmbh Implantatmaterial mit einer Träger-Wirkstoff-Kombination
US6201072B1 (en) 1997-10-03 2001-03-13 Macromed, Inc. Biodegradable low molecular weight triblock poly(lactide-co- glycolide) polyethylene glycol copolymers having reverse thermal gelation properties
US6004573A (en) * 1997-10-03 1999-12-21 Macromed, Inc. Biodegradable low molecular weight triblock poly(lactide-co-glycolide) polyethylene glycol copolymers having reverse thermal gelation properties
US6117949A (en) * 1998-10-01 2000-09-12 Macromed, Inc. Biodegradable low molecular weight triblock poly (lactide-co-glycolide) polyethylene glycol copolymers having reverse thermal gelation properties
WO1999018142A1 (en) * 1997-10-03 1999-04-15 Macromed, Inc. BIODEGRADABLE LOW MOLECULAR WEIGHT TRIBLOCK POLY(LACTIDE-co-GLYCOLIDE) POLYETHYLENE GLYCOL COPOLYMERS HAVING REVERSE THERMAL GELATION PROPERTIES
US7662409B2 (en) 1998-09-25 2010-02-16 Gel-Del Technologies, Inc. Protein matrix materials, devices and methods of making and using thereof
US7018645B1 (en) 2000-04-27 2006-03-28 Macromed, Inc. Mixtures of various triblock polyester polyethylene glycol copolymers having improved gel properties
JP2004524410A (ja) * 2001-03-23 2004-08-12 ガムリンク エー/エス チューインガム用の分解可能な樹脂置換体
DK1370153T4 (en) 2001-03-23 2015-05-18 Gumlink As COATED degradable CHEWING GUM WITH IMPROVED STABILITY AND PROCESS FOR THE PREPARATION OF THIS
AU2002324447B2 (en) 2001-06-22 2006-06-29 Durect Corporation Zero-order prolonged release coaxial implants
ES2304501T3 (es) * 2002-02-15 2008-10-16 Nektar Therapeutics Al, Corporation Polimeros a base de oxido de alquileno degradables hidroliticamente.
WO2003092468A2 (en) 2002-04-29 2003-11-13 Gel-Del Technologies, Inc. Biomatrix structural containment and fixation systems and methods of use thereof
US20060034797A1 (en) * 2002-05-03 2006-02-16 Arien Albertina M E Polymeric micromulsions
US7649023B2 (en) 2002-06-11 2010-01-19 Novartis Ag Biodegradable block copolymeric compositions for drug delivery
ES2417324T3 (es) 2002-09-06 2013-08-07 Cerulean Pharma Inc. Polímeros a base de ciclodextrina para el suministro de los agentes terapéuticos enlazados covalentemente a ellos
CN1668209A (zh) 2002-09-24 2005-09-14 古木林科有限公司 含至少一种高分子量生物可降解聚合物的生物可降解口香糖
MXPA05002961A (es) 2002-09-24 2005-06-03 Gumlink As Goma de mascar que comprende al menos dos diferentes polimeros biodegradables.
DK1474995T3 (da) 2003-05-06 2013-02-18 Gumlink As Fremgangsmåde til fremstilling af tyggegummigranulater, et gummisammensætningsekstruder- og granuleringssystem og et tyggegummiprodukt
ATE405170T1 (de) 2003-05-06 2008-09-15 Gumlink As Methode zur herstellung von kaugummigranulat und komprimierten kaugummiprodukten, sowie ein kaugummigranuliersystem
US8465537B2 (en) 2003-06-17 2013-06-18 Gel-Del Technologies, Inc. Encapsulated or coated stent systems
EP1660013A4 (en) 2003-08-26 2011-07-20 Gel Del Technologies Inc BIOMATERIAL AND PROTEIN BIOCOACERVATES, METHODS OF MAKING AND USING THEM
WO2005055945A2 (en) 2003-12-08 2005-06-23 Gel-Del Technologies, Inc. Mucoadhesive drug delivery devices and methods of making and using thereof
US20080176958A1 (en) 2007-01-24 2008-07-24 Insert Therapeutics, Inc. Cyclodextrin-based polymers for therapeutics delivery
US11890371B2 (en) 2007-12-26 2024-02-06 Petvivo Holdings, Inc. Biocompatible protein-based particles and methods thereof
WO2010057177A2 (en) 2008-11-17 2010-05-20 Gel-Del Technologies, Inc. Protein biomaterial and biocoacervate vessel graft systems and methods of making and using thereof
JP5855568B2 (ja) 2009-09-15 2016-02-09 セルリアン・ファーマ・インコーポレイテッド 癌の治療法
CN103037903A (zh) 2010-05-18 2013-04-10 天蓝制药公司 用于治疗自身免疫性疾病或其它疾病的组合物和方法
US20140094432A1 (en) 2012-10-02 2014-04-03 Cerulean Pharma Inc. Methods and systems for polymer precipitation and generation of particles
US20230285576A1 (en) 2020-08-05 2023-09-14 Ellipses Pharma Ltd Treatment of cancer using a cyclodextrin-containing polymer-topoisomerase inhibitor conjugate and a parp inhibitor

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3736646A (en) * 1971-10-18 1973-06-05 American Cyanamid Co Method of attaching surgical needles to multifilament polyglycolic acid absorbable sutures
US4047533A (en) * 1976-09-20 1977-09-13 American Cyanamid Company Absorbable surgical sutures coated with polyoxyethylene-polyoxypropylene copolymer lubricant
US4429080A (en) * 1982-07-01 1984-01-31 American Cyanamid Company Synthetic copolymer surgical articles and method of manufacturing the same
US4438253A (en) * 1982-11-12 1984-03-20 American Cyanamid Company Poly(glycolic acid)/poly(alkylene glycol) block copolymers and method of manufacturing the same
US4452973A (en) * 1982-11-12 1984-06-05 American Cyanamid Company Poly(glycolic acid)/poly(oxyethylene) triblock copolymers and method of manufacturing the same

Also Published As

Publication number Publication date
FI873840A7 (fi) 1988-03-06
FI873840L (fi) 1988-03-06
DE3786309T2 (de) 1994-02-10
HUT52945A (en) 1990-09-28
GR3008526T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1993-10-29
DK462287A (da) 1988-03-06
IL83764A (en) 1991-05-12
NZ221647A (en) 1990-09-26
AU7797087A (en) 1988-03-10
EP0258780A2 (en) 1988-03-09
IL83764A0 (en) 1988-02-29
CA1283988C (en) 1991-05-07
BR8704648A (pt) 1988-04-26
EP0258780B1 (en) 1993-06-23
KR880003985A (ko) 1988-05-31
AU605172B2 (en) 1991-01-10
DE3786309D1 (de) 1993-07-29
ES2058081T3 (es) 1994-11-01
DK462287D0 (da) 1987-09-04
FI873840A0 (fi) 1987-09-04
EP0258780A3 (en) 1988-05-18

Similar Documents

Publication Publication Date Title
HU205711B (en) Process for producing pharmaceutical compositions with slow release, having polyester carrier containing alkylene oxide blocks, and for producing the carrier
US4882168A (en) Polyesters containing alkylene oxide blocks as drug delivery systems
US4757128A (en) High molecular weight polyanhydride and preparation thereof
JP3220331B2 (ja) 非経口投与用の吸収性液体コポリマー類
AU2006271727B2 (en) Resorbable polyether esters for producing medical implants
CA1100041A (en) Absorbable pharmaceutical compositions based on isomorphic copolyoxalates
US4906474A (en) Bioerodible polyanhydrides for controlled drug delivery
US6350812B1 (en) Hydrogels containing triblock copolymers, and preparation and use thereof
FI80284C (fi) Farmaceutiskt eller veterinaert godtagbar amfipatisk blocksampolymer och dess framstaellning.
JPS63118326A (ja) アルキレンオキサイドのブロツクを含むポリエステル及び薬剤供給系としてのその使用
JP4170399B2 (ja) ホスフェートによって鎖延長化された生分解性ポリマー、組成物、物品、並びにその製造及び使用方法
US4891225A (en) Bioerodible polyanhydrides for controlled drug delivery
EP2590629B1 (en) Biodegradable phase separated segmented multi block co-polymers and release of biologically active polypeptides
US5688900A (en) Absorbable polyalkylene diglycolates
JP2002500640A (ja) ポリ脂環式ホスホエステル化合物よりなる生分解性組成物、物品、及びその使用方法
US20020155092A1 (en) Phosphate based biodegradable polymers
EP1642921B1 (en) Triblock copolymer, method for producing the same and biocompatible material
JP4015194B2 (ja) 制御された物理的状態と生物侵食性を持つポリマー
CN1823726A (zh) 一种可降解的温敏性物理水凝胶及其制备方法
US20050063941A1 (en) Biodegradable polymeric material for biomedical applications
KR100527408B1 (ko) 카프로락톤과 락티드의 랜덤공중합체와 폴리에테르를이용한 생분해성 블록공중합체의 제조방법 및 이의 응용
US6503528B1 (en) Polymeric compositions and a method of making the same

Legal Events

Date Code Title Description
HMM4 Cancellation of final prot. due to non-payment of fee