HU189608B - Process for producing pyridazine derivatives - Google Patents

Process for producing pyridazine derivatives Download PDF

Info

Publication number
HU189608B
HU189608B HU822546A HU254682A HU189608B HU 189608 B HU189608 B HU 189608B HU 822546 A HU822546 A HU 822546A HU 254682 A HU254682 A HU 254682A HU 189608 B HU189608 B HU 189608B
Authority
HU
Hungary
Prior art keywords
formula
compound
hydrogen
compounds
methyl
Prior art date
Application number
HU822546A
Other languages
English (en)
Hungarian (hu)
Inventor
Camille Wermuth
Jean-Pierre Chambon
Original Assignee
Sanofi,Fr
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi,Fr filed Critical Sanofi,Fr
Publication of HU189608B publication Critical patent/HU189608B/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D237/00Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D237/00Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/26Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
    • C07D237/30Phthalazines
    • C07D237/34Phthalazines with nitrogen atoms directly attached to carbon atoms of the nitrogen-containing ring, e.g. hydrazine radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D237/00Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/20Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
HU822546A 1981-08-11 1982-08-06 Process for producing pyridazine derivatives HU189608B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8115546A FR2511366A1 (fr) 1981-08-11 1981-08-11 Nouveaux derives de la pyridazine, leur procede de preparation et les medicaments, actifs sur le systeme nerveux central, qui en contiennent

Publications (1)

Publication Number Publication Date
HU189608B true HU189608B (en) 1986-07-28

Family

ID=9261385

Family Applications (1)

Application Number Title Priority Date Filing Date
HU822546A HU189608B (en) 1981-08-11 1982-08-06 Process for producing pyridazine derivatives

Country Status (30)

Country Link
US (1) US4710499A (US20020095090A1-20020718-M00002.png)
EP (1) EP0073161B1 (US20020095090A1-20020718-M00002.png)
JP (1) JPS5838263A (US20020095090A1-20020718-M00002.png)
KR (1) KR880002711B1 (US20020095090A1-20020718-M00002.png)
AR (1) AR231537A1 (US20020095090A1-20020718-M00002.png)
AT (1) ATE23042T1 (US20020095090A1-20020718-M00002.png)
AU (1) AU579570B2 (US20020095090A1-20020718-M00002.png)
CA (1) CA1179347A (US20020095090A1-20020718-M00002.png)
CS (1) CS239929B2 (US20020095090A1-20020718-M00002.png)
DD (1) DD202550A5 (US20020095090A1-20020718-M00002.png)
DE (1) DE3273893D1 (US20020095090A1-20020718-M00002.png)
DK (1) DK148596C (US20020095090A1-20020718-M00002.png)
EG (1) EG15749A (US20020095090A1-20020718-M00002.png)
ES (1) ES8305736A1 (US20020095090A1-20020718-M00002.png)
FI (1) FI72970C (US20020095090A1-20020718-M00002.png)
FR (1) FR2511366A1 (US20020095090A1-20020718-M00002.png)
GR (1) GR76236B (US20020095090A1-20020718-M00002.png)
HU (1) HU189608B (US20020095090A1-20020718-M00002.png)
IE (1) IE53493B1 (US20020095090A1-20020718-M00002.png)
IL (1) IL66424A (US20020095090A1-20020718-M00002.png)
MA (1) MA19559A1 (US20020095090A1-20020718-M00002.png)
NO (1) NO158871C (US20020095090A1-20020718-M00002.png)
NZ (1) NZ201553A (US20020095090A1-20020718-M00002.png)
OA (1) OA07179A (US20020095090A1-20020718-M00002.png)
PH (1) PH18921A (US20020095090A1-20020718-M00002.png)
PL (1) PL137200B1 (US20020095090A1-20020718-M00002.png)
PT (1) PT75372B (US20020095090A1-20020718-M00002.png)
SU (1) SU1356960A3 (US20020095090A1-20020718-M00002.png)
YU (1) YU171682A (US20020095090A1-20020718-M00002.png)
ZA (1) ZA825515B (US20020095090A1-20020718-M00002.png)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2539741A1 (fr) * 1983-01-21 1984-07-27 Sanofi Sa Composes a noyau heterocyclique diazote, leur procede de preparation et les medicaments, actifs sur le systeme nerveux central, qui en contiennent
US5001125A (en) * 1984-03-26 1991-03-19 Janssen Pharmaceutica N.V. Anti-virally active pyridazinamines
JPS60218377A (ja) * 1984-04-16 1985-11-01 Mitsubishi Yuka Yakuhin Kk 4−フエニルフタラジン誘導体及びそれを有効成分とする循環改善剤
EP0190563B1 (de) * 1985-01-14 1989-08-02 Boehringer Ingelheim Kg Neue 12-Amino-pyridazino[4',5':3,4]pyrrolo-[2,1-a]isochinoline, Verfahren zu ihrer Herstellung und ihre Verwendung
US5106973A (en) * 1987-11-23 1992-04-21 Janssen Pharmaceutica N.V. Pyridzainamine derivatives
ES2114654T3 (es) 1993-06-08 1998-06-01 Vertex Pharma Piridazinas como inhibidores de la enzima de conversion de la interleuquina-1beta.
US20100210590A1 (en) * 1995-09-27 2010-08-19 Northwestern University Compositions and treatments for seizure-related disorders
GB9707693D0 (en) * 1997-04-16 1997-06-04 Smithkline Beecham Plc Novel method of treatment
EP2264014A1 (en) * 2001-08-31 2010-12-22 Université Louis Pasteur Substituted pyridazines as anti-inflammatory agents and protein kinase inhibitors
EP1812007B1 (en) * 2004-11-02 2011-09-07 Northwestern University Pyridazine compounds and methods
BRPI0517947A (pt) * 2004-11-02 2008-10-21 Univ Northwestern composto de piridazina, composições e métodos
EP2015751A2 (en) * 2006-04-28 2009-01-21 Northwestern University Salts of pyridazine compounds
JP2009535344A (ja) * 2006-04-28 2009-10-01 ノースウェスタン ユニバーシティ 神経炎症性疾患の処置のためのピリダジン化合物を含む処方物
CA2650711A1 (en) * 2006-04-28 2007-11-08 Northwestern University Compositions and treatments using pyridazine compounds and cholinesterase inhibitors
AU2008223066A1 (en) * 2007-03-02 2008-09-12 Northwestern University Compositions comprising derivatives of 3 -phenylpyridazine for treating seizure-related disorders

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1345880A (en) * 1971-06-18 1974-02-06 Cepbepe Pyridazine derivatives
FR2473522A1 (fr) * 1980-01-16 1981-07-17 Synthelabo Nouveaux derives substitues de dihydro-2,3 imidazo(1,2-b)pyridazines et les medicaments, utiles notamment comme antidepresseurs, qui en contiennent

Also Published As

Publication number Publication date
AU579570B2 (en) 1988-12-01
FR2511366B1 (US20020095090A1-20020718-M00002.png) 1984-12-14
PL137200B1 (en) 1986-05-31
DD202550A5 (de) 1983-09-21
JPS5838263A (ja) 1983-03-05
FI822768A0 (fi) 1982-08-09
US4710499A (en) 1987-12-01
DK148596C (da) 1986-01-13
NO158871B (no) 1988-08-01
NO158871C (no) 1988-11-09
FI822768L (fi) 1983-02-11
NZ201553A (en) 1985-08-16
YU171682A (en) 1985-03-20
KR840001147A (ko) 1984-03-28
NO822717L (no) 1983-02-14
ES514887A0 (es) 1983-04-16
DK148596B (da) 1985-08-12
DE3273893D1 (en) 1986-11-27
PT75372A (en) 1982-09-01
PL237836A1 (en) 1983-02-28
AU8702982A (en) 1983-05-12
CS239929B2 (en) 1986-01-16
EG15749A (en) 1986-09-30
IL66424A (en) 1985-10-31
FI72970C (fi) 1987-08-10
ZA825515B (en) 1983-06-29
OA07179A (fr) 1984-04-30
IE53493B1 (en) 1988-11-23
ES8305736A1 (es) 1983-04-16
FR2511366A1 (fr) 1983-02-18
ATE23042T1 (de) 1986-11-15
DK358782A (da) 1983-02-12
EP0073161A1 (fr) 1983-03-02
SU1356960A3 (ru) 1987-11-30
KR880002711B1 (ko) 1988-12-26
PT75372B (en) 1984-12-10
PH18921A (en) 1985-11-11
EP0073161B1 (fr) 1986-10-22
AR231537A1 (es) 1984-12-28
MA19559A1 (fr) 1983-04-01
GR76236B (US20020095090A1-20020718-M00002.png) 1984-08-04
FI72970B (fi) 1987-04-30
IE821822L (en) 1983-02-11
IL66424A0 (en) 1982-11-30
JPH0456032B2 (US20020095090A1-20020718-M00002.png) 1992-09-07
CA1179347A (en) 1984-12-11

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Legal Events

Date Code Title Description
HU90 Patent valid on 900628
HMM4 Cancellation of final prot. due to non-payment of fee