HU179245B - Process for preparing 1-aryloxy-3-nitrato-alkylamino-2-propanol derivatives - Google Patents

Process for preparing 1-aryloxy-3-nitrato-alkylamino-2-propanol derivatives Download PDF

Info

Publication number
HU179245B
HU179245B HU79ME2248A HUME002248A HU179245B HU 179245 B HU179245 B HU 179245B HU 79ME2248 A HU79ME2248 A HU 79ME2248A HU ME002248 A HUME002248 A HU ME002248A HU 179245 B HU179245 B HU 179245B
Authority
HU
Hungary
Prior art keywords
formula
defined above
compounds
acid
propanol
Prior art date
Application number
HU79ME2248A
Other languages
English (en)
Hungarian (hu)
Inventor
Johannes Sombroek
Karl-Heinz Becker
Klaus O Minck
Hans-Joachim Enekel
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of HU179245B publication Critical patent/HU179245B/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Quinoline Compounds (AREA)
HU79ME2248A 1978-02-09 1979-02-08 Process for preparing 1-aryloxy-3-nitrato-alkylamino-2-propanol derivatives HU179245B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19782805404 DE2805404A1 (de) 1978-02-09 1978-02-09 1-aryloxy-3-nitratoalkylamino-2-propanole und verfahren zu ihrer herstellung

Publications (1)

Publication Number Publication Date
HU179245B true HU179245B (en) 1982-09-28

Family

ID=6031499

Family Applications (1)

Application Number Title Priority Date Filing Date
HU79ME2248A HU179245B (en) 1978-02-09 1979-02-08 Process for preparing 1-aryloxy-3-nitrato-alkylamino-2-propanol derivatives

Country Status (11)

Country Link
US (1) US4288452A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (1) EP0004532B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPS54122235A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) AT366662B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU524270B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA1129421A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (2) DE2805404A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES477563A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HU (1) HU179245B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IL (1) IL56612A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ZA (1) ZA79575B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56113748A (en) * 1980-02-13 1981-09-07 Kowa Co Aminoethanol derivative and its preparation
US4394382A (en) * 1980-06-17 1983-07-19 Kowa Company, Ltd. Dihydrobenzopyran compounds and pharmaceutical composition comprising said compounds
CH655110A5 (de) * 1982-09-03 1986-03-27 Otsuka Pharma Co Ltd Carbostyrilderivate, verfahren zu deren herstellung und arzneimittel, welche diese enthalten.
DE3426419A1 (de) * 1984-07-18 1986-01-23 Boehringer Mannheim Gmbh, 6800 Mannheim Neue oxindol-derivate, verfahren zu ihrer herstellung, diese verbindungen enthaltende arzneimittel und zwischenprodukte
DE3512627A1 (de) * 1985-04-06 1986-10-09 Boehringer Mannheim Gmbh, 6800 Mannheim Amino-propanol-derivate, verfahren zu deren herstellung, verwendung derselben und diese enthaltende arzneimittel
DE3705622A1 (de) * 1987-02-21 1988-09-01 Boehringer Mannheim Gmbh Neue amino-propanol-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel sowie zwischenprodukte
AU2061588A (en) * 1987-09-07 1989-03-09 Imperial Chemical Industries Plc Phenol ester of xamoterol
DE68920797T2 (de) * 1988-08-10 1995-06-29 Otsuka Pharma Co Ltd Herzmittel.
US5254595A (en) * 1988-12-23 1993-10-19 Elf Sanofi Aryloxypropanolaminotetralins, a process for their preparation and pharmaceutical compositions containing them
WO1997000239A1 (fr) * 1995-06-14 1997-01-03 Sankyo Company, Limited Medicament contre l'angine contenant un derive nitroxy comme ingredient actif
ZA967892B (en) * 1995-09-21 1998-03-18 Lilly Co Eli Selective β3 adrenergic agonists.
US6075040A (en) 1996-09-05 2000-06-13 Eli Lilly And Company Selective β3 adrenergic agonists
DE69711519T2 (de) * 1996-09-05 2002-10-31 Eli Lilly And Co., Indianapolis Carbazolanaloge als selektive beta3-adrenergische Agonisten
EP0893440A1 (en) * 1997-07-22 1999-01-27 Roche Diagnostics GmbH Thermodynamically stable modification of 1-(4-carbazolyloxy)-3-[2-(2-methoxyphenoxy)ethylamino]-2-propanole, process for its preparation and pharmaceutical compositions containing it
CO5011072A1 (es) * 1997-12-05 2001-02-28 Lilly Co Eli Etanolaminas pirazinil substituidas como agfonistas de los receptores
IT1314184B1 (it) * 1999-08-12 2002-12-06 Nicox Sa Composizioni farmaceutiche per la terapia di condizioni di stressossidativo
CA2536173A1 (en) * 2003-08-20 2005-03-03 Nitromed, Inc. Nitrosated and nitrosylated cardiovascular compounds, compositions and methods of use
ATE358478T1 (de) * 2003-12-02 2007-04-15 Nicox Sa Nitrooxy-derivate von carvedilol und anderen betablockern als antihypertensiva
WO2006052899A2 (en) * 2004-11-08 2006-05-18 Nitromed, Inc. Nitrosated and nitrosylated compounds, compositions and methods for the treatment of ophthalmic disorders
WO2007044968A2 (en) 2005-10-12 2007-04-19 Genencor International, Inc. Stable, durable granules with active agents
JP4952284B2 (ja) * 2007-02-15 2012-06-13 日本精工株式会社 軸受用密封装置及び軸受ユニット

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH300197A (de) * 1951-10-24 1954-07-15 Cilag Ag Verfahren zur Herstellung eines neuen Salpetersäureesters.
NL110701C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1960-03-14
NL301580A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1962-12-11
NL163775C (nl) * 1967-12-18 1980-10-15 Boehringer Sohn Ingelheim Werkwijze ter bereiding van farmaceutische preparaten met beta-receptoren blokkerende werking, alsmede werkwijze ter bereiding van 1-(cyaanfenoxy)-2-hydroxy-3-(sec.alkylamino) propaanderivaten.
BE741762A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1968-11-18 1970-05-19
US4167581A (en) * 1972-12-15 1979-09-11 Imperial Chemical Industries Limited Alkanolamine derivatives and pharmaceutical compositions and uses thereof
US4083992A (en) * 1972-12-15 1978-04-11 Imperial Chemical Industries Limited Alkanolamine derivatives
AT330150B (de) * 1973-02-28 1976-06-10 Boehringer Sohn Ingelheim Verfahren zur herstellung von neuen 1-phenoxy-2-hydroxy -3- propargylaminopropanen und von deren saureadditionssalzen
ZA741812B (en) * 1973-04-18 1975-04-30 Haessle A New amines and process for their preparation
ZA742728B (en) * 1973-05-08 1975-04-30 Simes Pharmaceutical composition for the treatment of coronaric ailments

Also Published As

Publication number Publication date
JPS54122235A (en) 1979-09-21
ES477563A1 (es) 1979-06-16
JPS6313979B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1988-03-29
DE2960954D1 (en) 1981-12-24
DE2805404A1 (de) 1979-08-16
EP0004532B1 (de) 1981-10-14
ZA79575B (en) 1980-04-30
AU4406379A (en) 1979-08-16
US4288452A (en) 1981-09-08
EP0004532A1 (de) 1979-10-17
CA1129421A (en) 1982-08-10
AT366662B (de) 1982-04-26
IL56612A0 (en) 1979-05-31
ATA95079A (de) 1981-09-15
AU524270B2 (en) 1982-09-09
IL56612A (en) 1982-03-31

Similar Documents

Publication Publication Date Title
HU179245B (en) Process for preparing 1-aryloxy-3-nitrato-alkylamino-2-propanol derivatives
CA1124241A (en) N-alkylated aminoalcohols and their salts, processes for their preparation and pharmaceutical preparations containing these compounds
US3998790A (en) Phenoxy-hydroxypropylamines, their preparation, and method and pharmaceutical preparations for treating cardiovascular diseases
US3966749A (en) Novel synthesis of optically active m-acyloxy-α-[(methylamino)methyl]benzyl alcohols, the pharmaceutically acceptable acid addition salts thereof and intermediate useful in the preparation thereof
CS201040B2 (en) Method of producing etherified hydroxy-benzo-diheterocyclic compounds
HU207988B (en) Process for producing halogenides of o-/3-amino-2-hydroxy-propyl/hydroximic acid and pharmaceutical compositions containing them as active components
US4191765A (en) 1-Aryloxy-2-hydroxy-3-aminopropanes
JP2601008B2 (ja) ナフチルオキサゾリドン誘導体、その製法及びその合成中間体
CS89592A3 (en) Novel indole derivative, process of its preparation and a pharmaceuticalcomprising thereof
DK164660B (da) Analogifremgangsmaade til fremstilling af forbindelser, som er velegnede til behandling eller forebyggelse af hjertesygdomme
US4482562A (en) Aromatic aminoethanol compounds, and utilization thereof as cardiovascular agents
NO161543B (no) Sprengladning for bruk ved skjoeting av roer ved eksplosjonssveising.
DK143128B (da) Analogifremgan&smaade til fremstilling af 1-aryloxy-2-hydroxy-3-alkylaminopropaner eller deres fysiologisk acceptable syreadditionssalte
JPS62212354A (ja) 環状中間体を用いたフエノ−ルエ−テルの製法
JP3606326B2 (ja) 欝病、不安神経症およびパーキンソン病を治療するための１−アリールシクロアルキルスルフィド、スルホキシドおよびスルホン
CS239948B2 (en) Processing of substitute n-carboxamidealkylfenoxypropanolamine
CA2508623A1 (en) Benzomorpholine derivatives
NO115028B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JPS5988467A (ja) フエノキシアミノプロパノ−ル誘導体
NO132835B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PL90714B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
US2740795A (en) Isoindolineicompounds
CS249503B2 (en) Method of new 1-(3-/3,4,5-trimethoxyphenoxy/-2-hydroxypropyl-4-aryl-piperazine derivatives production
RU2045521C1 (ru) Производные 1,2,4-триазолилтиоамидов
JPS6059230B2 (ja) 不整脈抑制性フエネチルピペリジン化合物