HU0103658D0 - Method for producing (-)-alpha-(difluoromethyl)ornithine-monohydrochloride monohydrate - Google Patents
Method for producing (-)-alpha-(difluoromethyl)ornithine-monohydrochloride monohydrateInfo
- Publication number
- HU0103658D0 HU0103658D0 HU0103658A HUP0103658A HU0103658D0 HU 0103658 D0 HU0103658 D0 HU 0103658D0 HU 0103658 A HU0103658 A HU 0103658A HU P0103658 A HUP0103658 A HU P0103658A HU 0103658 D0 HU0103658 D0 HU 0103658D0
- Authority
- HU
- Hungary
- Prior art keywords
- difluoromethyl
- ornithine
- alpha
- producing
- monohydrochloride monohydrate
- Prior art date
Links
- FJPAMFNRCFEGSD-QYCVXMPOSA-N (2s)-2,5-diamino-2-(difluoromethyl)pentanoic acid;hydrate;hydrochloride Chemical compound O.Cl.NCCC[C@@](N)(C(F)F)C(O)=O FJPAMFNRCFEGSD-QYCVXMPOSA-N 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/30—Preparation of optical isomers
- C07C227/34—Preparation of optical isomers by separation of optical isomers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/26—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having more than one amino group bound to the carbon skeleton, e.g. lysine
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Analytical Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP98117982 | 1998-09-23 | ||
| PCT/EP1999/007060 WO2000017153A1 (de) | 1998-09-23 | 1999-09-22 | VERFAHREN ZUR HERSTELLUNG VON (-)-α-(DIFLUORMETHYL)ORNITHIN-MONOHYDROCHLORID MONOHYDRAT |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| HU0103658D0 true HU0103658D0 (en) | 2002-02-28 |
| HUP0103658A2 HUP0103658A2 (hu) | 2002-12-28 |
| HUP0103658A3 HUP0103658A3 (en) | 2003-03-28 |
Family
ID=8232678
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU0103658A HUP0103658A3 (en) | 1998-09-23 | 1999-09-22 | Method for producing (-)-alpha-(difluoromethyl)ornithine-monohydrochloride monohydrate |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US6462229B1 (hu) |
| EP (1) | EP1115696A1 (hu) |
| JP (1) | JP2002526468A (hu) |
| KR (1) | KR20010079913A (hu) |
| CN (1) | CN1319085A (hu) |
| AU (1) | AU764154B2 (hu) |
| BR (1) | BR9914034A (hu) |
| CA (1) | CA2345112A1 (hu) |
| CZ (1) | CZ20011043A3 (hu) |
| HU (1) | HUP0103658A3 (hu) |
| IL (1) | IL142218A0 (hu) |
| MX (1) | MXPA01003032A (hu) |
| NO (1) | NO20011480L (hu) |
| PL (1) | PL195164B1 (hu) |
| SK (1) | SK4092001A3 (hu) |
| WO (1) | WO2000017153A1 (hu) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004063141A1 (ja) * | 2003-01-16 | 2004-07-29 | Toray Fine Chemicals Co,. Ltd. | 光学活性ジアシル酒石酸の回収方法 |
| WO2005021502A1 (ja) * | 2003-08-29 | 2005-03-10 | Takeda Pharmaceutical Company Limited | 光学活性トレオ−β−アルキルトリプトファン誘導体の製造法およびその中間体 |
| TW201617326A (zh) * | 2014-03-06 | 2016-05-16 | Ａｌｐｈｏｒａ研發股份有限公司 | （ｓ）－１－（（２ｒ，３ｒ，４ｓ，５ｓ）－５－烯丙－３－甲氧－４－（對甲苯磺醯甲基）四氫呋喃－２－基）－３－氨基丙－２－醇之結晶衍生物 |
| JP2018507910A (ja) * | 2015-02-12 | 2018-03-22 | ジ・アリゾナ・ボード・オブ・リージェンツ・オン・ビハーフ・オブ・ジ・ユニバーシティ・オブ・アリゾナ | 神経芽細胞腫を治療する方法 |
| CN105660637B (zh) * | 2016-01-07 | 2018-04-24 | 南京中医药大学 | 防治当归早薹的药物及其应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4309442A (en) * | 1977-07-11 | 1982-01-05 | Merrell Toraude Et Compagnie | Method for controlling fertility in mammals |
| US4414141A (en) | 1980-11-21 | 1983-11-08 | The Lummus Company | Hydrotreating catalyst |
| US4931557A (en) * | 1988-10-17 | 1990-06-05 | Eli Lilly And Company | Method of resolving cis 3-amino-4-(2-furyl)vinyl)-1-methoxycarbonylmethyl-azetidin-2-one and di-p-toluoyl-tartaric acid salts thereof |
| DE69724095T2 (de) * | 1996-10-04 | 2004-05-27 | Ilex Oncology, Inc., San Antonio | DFMO und Taxol zur Behandlung bzw. Vorbeugung von Brustkrebs |
| AU5526898A (en) * | 1996-12-13 | 1998-07-03 | Ilex Oncology, Inc. | Isomeric pharmaceutical formulation containing dfmo for the treatment of cancer |
-
1999
- 1999-09-22 US US09/787,420 patent/US6462229B1/en not_active Expired - Fee Related
- 1999-09-22 WO PCT/EP1999/007060 patent/WO2000017153A1/de not_active Application Discontinuation
- 1999-09-22 CN CN99811257A patent/CN1319085A/zh active Pending
- 1999-09-22 KR KR1020017003766A patent/KR20010079913A/ko not_active Application Discontinuation
- 1999-09-22 AU AU60865/99A patent/AU764154B2/en not_active Ceased
- 1999-09-22 EP EP99947408A patent/EP1115696A1/de not_active Withdrawn
- 1999-09-22 MX MXPA01003032A patent/MXPA01003032A/es not_active Application Discontinuation
- 1999-09-22 IL IL14221899A patent/IL142218A0/xx unknown
- 1999-09-22 CA CA002345112A patent/CA2345112A1/en not_active Abandoned
- 1999-09-22 SK SK409-2001A patent/SK4092001A3/sk unknown
- 1999-09-22 PL PL99346900A patent/PL195164B1/pl not_active IP Right Cessation
- 1999-09-22 JP JP2000574063A patent/JP2002526468A/ja active Pending
- 1999-09-22 HU HU0103658A patent/HUP0103658A3/hu unknown
- 1999-09-22 BR BR9914034-9A patent/BR9914034A/pt not_active IP Right Cessation
- 1999-09-22 CZ CZ20011043A patent/CZ20011043A3/cs unknown
-
2001
- 2001-03-22 NO NO20011480A patent/NO20011480L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| IL142218A0 (en) | 2002-03-10 |
| WO2000017153A1 (de) | 2000-03-30 |
| SK4092001A3 (en) | 2002-06-04 |
| AU6086599A (en) | 2000-04-10 |
| PL195164B1 (pl) | 2007-08-31 |
| BR9914034A (pt) | 2001-08-14 |
| JP2002526468A (ja) | 2002-08-20 |
| MXPA01003032A (es) | 2002-07-02 |
| NO20011480L (no) | 2001-03-23 |
| CA2345112A1 (en) | 2000-03-30 |
| HUP0103658A3 (en) | 2003-03-28 |
| EP1115696A1 (de) | 2001-07-18 |
| CZ20011043A3 (cs) | 2001-09-12 |
| CN1319085A (zh) | 2001-10-24 |
| US6462229B1 (en) | 2002-10-08 |
| AU764154B2 (en) | 2003-08-14 |
| NO20011480D0 (no) | 2001-03-22 |
| KR20010079913A (ko) | 2001-08-22 |
| PL346900A1 (en) | 2002-03-11 |
| HUP0103658A2 (hu) | 2002-12-28 |
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