HU0102040D0 - Purified gabapentine binding protein - Google Patents
Purified gabapentine binding proteinInfo
- Publication number
- HU0102040D0 HU0102040D0 HU0102040A HU0102040A HU0102040D0 HU 0102040 D0 HU0102040 D0 HU 0102040D0 HU 0102040 A HU0102040 A HU 0102040A HU 0102040 A HU0102040 A HU 0102040A HU 0102040 D0 HU0102040 D0 HU 0102040D0
- Authority
- HU
- Hungary
- Prior art keywords
- binding protein
- gabapentine
- purified
- treatment
- terminal sequence
- Prior art date
Links
- UGJMXCAKCUNAIE-UHFFFAOYSA-N Gabapentin Chemical compound OC(=O)CC1(CN)CCCCC1 UGJMXCAKCUNAIE-UHFFFAOYSA-N 0.000 title abstract 5
- 229960002870 gabapentin Drugs 0.000 title abstract 3
- 102000014914 Carrier Proteins Human genes 0.000 title abstract 2
- 108091008324 binding proteins Proteins 0.000 title abstract 2
- 208000019901 Anxiety disease Diseases 0.000 abstract 1
- 241000283973 Oryctolagus cuniculus Species 0.000 abstract 1
- 206010033664 Panic attack Diseases 0.000 abstract 1
- 230000036506 anxiety Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- -1 cyclic amino acids Chemical class 0.000 abstract 1
- 208000019906 panic disease Diseases 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 210000002027 skeletal muscle Anatomy 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Anesthesiology (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Peptides Or Proteins (AREA)
- Indole Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US28128594A | 1994-07-27 | 1994-07-27 | |
| US08/445,398 US5792796A (en) | 1994-07-27 | 1995-06-06 | Methods for treating anxiety and panic |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HU0102040D0 true HU0102040D0 (en) | 2001-07-30 |
Family
ID=26960801
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU0102041A HU0102041D0 (en) | 1994-07-27 | 1995-07-11 | Pharmacological compounds which bind to [3h]-gabapentine binding protein |
| HU9700238A HU223841B1 (hu) | 1994-07-27 | 1995-07-11 | Gabepentin alkalmazása szorongás és pánik kezelésére alkalmazható gyógyszerkészítmények előállítására |
| HU0102040A HU0102040D0 (en) | 1994-07-27 | 1995-07-11 | Purified gabapentine binding protein |
| HU0102043A HU0102043D0 (en) | 1994-07-27 | 1995-07-11 | Pharmaceutical compounds which interact with an ca2+ channel alpha2delta subunit |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU0102041A HU0102041D0 (en) | 1994-07-27 | 1995-07-11 | Pharmacological compounds which bind to [3h]-gabapentine binding protein |
| HU9700238A HU223841B1 (hu) | 1994-07-27 | 1995-07-11 | Gabepentin alkalmazása szorongás és pánik kezelésére alkalmazható gyógyszerkészítmények előállítására |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU0102043A HU0102043D0 (en) | 1994-07-27 | 1995-07-11 | Pharmaceutical compounds which interact with an ca2+ channel alpha2delta subunit |
Country Status (18)
| Country | Link |
|---|---|
| EP (1) | EP0804182B1 (hu) |
| JP (1) | JPH10503490A (hu) |
| AT (1) | ATE218334T1 (hu) |
| AU (1) | AU703428B2 (hu) |
| CA (1) | CA2193384C (hu) |
| CZ (1) | CZ291757B6 (hu) |
| DE (1) | DE69526972T2 (hu) |
| DK (1) | DK0804182T3 (hu) |
| ES (1) | ES2176334T3 (hu) |
| HU (4) | HU0102041D0 (hu) |
| MX (1) | MX9606674A (hu) |
| NZ (1) | NZ290050A (hu) |
| PL (1) | PL187064B1 (hu) |
| PT (1) | PT804182E (hu) |
| RO (1) | RO120041B1 (hu) |
| RU (1) | RU2168982C2 (hu) |
| SK (1) | SK283711B6 (hu) |
| WO (1) | WO1996003122A2 (hu) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5712158A (en) * | 1995-06-06 | 1998-01-27 | Warner-Lambert Company | Cell line for the rapid expression of functional calcium channels |
| US6372792B1 (en) | 1996-04-26 | 2002-04-16 | Guy Chouinard | Method for treating anxiety, anxiety disorders and insomnia |
| KR100491282B1 (ko) | 1996-07-24 | 2005-05-24 | 워너-램버트 캄파니 엘엘씨 | 통증 치료용 이소부틸가바 및 그의 유도체 |
| DE69834204T2 (de) | 1997-10-27 | 2007-03-29 | Warner-Lambert Co. Llc | Zyklische aminosäuren und deren derivate als arzneimittel |
| EP1082306A1 (en) | 1998-05-26 | 2001-03-14 | Warner-Lambert Company | Conformationally constrained amino acid compounds having affinity for the alpha2delta subunit of a calcium channel |
| FR2781793B1 (fr) * | 1998-08-03 | 2001-07-20 | Prographarm Lab | Procede de fabrication de granules de gabapentine enrobes |
| JP2003512602A (ja) * | 1999-09-16 | 2003-04-02 | ワーナー−ランバート・カンパニー | α２δ−１サブユニット結合リガンドのスクリーニング方法 |
| RU2377234C2 (ru) * | 2003-09-17 | 2009-12-27 | Ксенопорт, Инк. | Лечение или предупреждение синдрома беспокойных ног с использованием пролекарств аналогов гамк |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2016465A1 (en) * | 1989-06-02 | 1990-12-02 | Zola Phillip Horovitz | Method for preventing or treating anxiety employing a calcium channel blocker |
| US5189026A (en) * | 1991-06-07 | 1993-02-23 | Fractal Laboratories, Inc. | Treatment of human diseases involving dysregulation or dysfunction of the nervous system |
| SK283281B6 (sk) * | 1992-05-20 | 2003-05-02 | Northwestern University | Deriváty gamaaminomaslovej kyseliny, spôsoby a medziprodukty na ich výrobu, ich použitie a farmaceutické prostriedky |
-
1995
- 1995-07-11 CZ CZ1997162A patent/CZ291757B6/cs not_active IP Right Cessation
- 1995-07-11 AU AU30069/95A patent/AU703428B2/en not_active Ceased
- 1995-07-11 WO PCT/US1995/008702 patent/WO1996003122A2/en active IP Right Grant
- 1995-07-11 SK SK90-97A patent/SK283711B6/sk unknown
- 1995-07-11 DK DK95926249T patent/DK0804182T3/da active
- 1995-07-11 ES ES95926249T patent/ES2176334T3/es not_active Expired - Lifetime
- 1995-07-11 CA CA002193384A patent/CA2193384C/en not_active Expired - Fee Related
- 1995-07-11 RO RO97-00128A patent/RO120041B1/ro unknown
- 1995-07-11 HU HU0102041A patent/HU0102041D0/hu unknown
- 1995-07-11 MX MX9606674A patent/MX9606674A/es active IP Right Grant
- 1995-07-11 HU HU9700238A patent/HU223841B1/hu not_active IP Right Cessation
- 1995-07-11 NZ NZ290050A patent/NZ290050A/xx unknown
- 1995-07-11 EP EP95926249A patent/EP0804182B1/en not_active Expired - Lifetime
- 1995-07-11 RU RU97101109/14A patent/RU2168982C2/ru not_active IP Right Cessation
- 1995-07-11 PL PL95318268A patent/PL187064B1/pl not_active IP Right Cessation
- 1995-07-11 DE DE69526972T patent/DE69526972T2/de not_active Expired - Fee Related
- 1995-07-11 PT PT95926249T patent/PT804182E/pt unknown
- 1995-07-11 JP JP8505766A patent/JPH10503490A/ja not_active Ceased
- 1995-07-11 HU HU0102040A patent/HU0102040D0/hu unknown
- 1995-07-11 HU HU0102043A patent/HU0102043D0/hu unknown
- 1995-07-11 AT AT95926249T patent/ATE218334T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| WO1996003122A3 (en) | 1996-07-18 |
| DE69526972T2 (de) | 2002-11-21 |
| CA2193384A1 (en) | 1996-02-08 |
| CA2193384C (en) | 2002-03-19 |
| EP0804182B1 (en) | 2002-06-05 |
| PL187064B1 (pl) | 2004-05-31 |
| SK283711B6 (sk) | 2003-12-02 |
| HUT76835A (en) | 1997-11-28 |
| MX9606674A (es) | 1997-03-29 |
| HU0102043D0 (en) | 2001-07-30 |
| PT804182E (pt) | 2002-10-31 |
| ES2176334T3 (es) | 2002-12-01 |
| CZ291757B6 (cs) | 2003-05-14 |
| SK9097A3 (en) | 1998-05-06 |
| AU3006995A (en) | 1996-02-22 |
| EP0804182A2 (en) | 1997-11-05 |
| HU0102041D0 (en) | 2001-07-30 |
| CZ16297A3 (en) | 1997-07-16 |
| WO1996003122A2 (en) | 1996-02-08 |
| PL318268A1 (en) | 1997-05-26 |
| AU703428B2 (en) | 1999-03-25 |
| DK0804182T3 (da) | 2002-09-09 |
| RU2168982C2 (ru) | 2001-06-20 |
| DE69526972D1 (de) | 2002-07-11 |
| NZ290050A (en) | 1999-08-30 |
| HU223841B1 (hu) | 2005-02-28 |
| RO120041B1 (ro) | 2005-08-30 |
| ATE218334T1 (de) | 2002-06-15 |
| JPH10503490A (ja) | 1998-03-31 |
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