HU0102043D0 - Pharmaceutical compounds which interact with an ca2+ channel alpha2delta subunit - Google Patents

Pharmaceutical compounds which interact with an ca2+ channel alpha2delta subunit

Info

Publication number
HU0102043D0
HU0102043D0 HU0102043A HU0102043A HU0102043D0 HU 0102043 D0 HU0102043 D0 HU 0102043D0 HU 0102043 A HU0102043 A HU 0102043A HU 0102043 A HU0102043 A HU 0102043A HU 0102043 D0 HU0102043 D0 HU 0102043D0
Authority
HU
Hungary
Prior art keywords
channel
subunit
interact
pharmaceutical compounds
treatment
Prior art date
Application number
HU0102043A
Other languages
English (en)
Inventor
Jason P Brown
Nicolas S Gee
Lakhbir Shing
Geoffrey Neil Woodruff
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/445,398 external-priority patent/US5792796A/en
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of HU0102043D0 publication Critical patent/HU0102043D0/hu

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Anesthesiology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Indole Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
HU0102043A 1994-07-27 1995-07-11 Pharmaceutical compounds which interact with an ca2+ channel alpha2delta subunit HU0102043D0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28128594A 1994-07-27 1994-07-27
US08/445,398 US5792796A (en) 1994-07-27 1995-06-06 Methods for treating anxiety and panic

Publications (1)

Publication Number Publication Date
HU0102043D0 true HU0102043D0 (en) 2001-07-30

Family

ID=26960801

Family Applications (4)

Application Number Title Priority Date Filing Date
HU0102040A HU0102040D0 (en) 1994-07-27 1995-07-11 Purified gabapentine binding protein
HU0102043A HU0102043D0 (en) 1994-07-27 1995-07-11 Pharmaceutical compounds which interact with an ca2+ channel alpha2delta subunit
HU9700238A HU223841B1 (hu) 1994-07-27 1995-07-11 Gabepentin alkalmazása szorongás és pánik kezelésére alkalmazható gyógyszerkészítmények előállítására
HU0102041A HU0102041D0 (en) 1994-07-27 1995-07-11 Pharmacological compounds which bind to [3h]-gabapentine binding protein

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HU0102040A HU0102040D0 (en) 1994-07-27 1995-07-11 Purified gabapentine binding protein

Family Applications After (2)

Application Number Title Priority Date Filing Date
HU9700238A HU223841B1 (hu) 1994-07-27 1995-07-11 Gabepentin alkalmazása szorongás és pánik kezelésére alkalmazható gyógyszerkészítmények előállítására
HU0102041A HU0102041D0 (en) 1994-07-27 1995-07-11 Pharmacological compounds which bind to [3h]-gabapentine binding protein

Country Status (18)

Country Link
EP (1) EP0804182B1 (hu)
JP (1) JPH10503490A (hu)
AT (1) ATE218334T1 (hu)
AU (1) AU703428B2 (hu)
CA (1) CA2193384C (hu)
CZ (1) CZ291757B6 (hu)
DE (1) DE69526972T2 (hu)
DK (1) DK0804182T3 (hu)
ES (1) ES2176334T3 (hu)
HU (4) HU0102040D0 (hu)
MX (1) MX9606674A (hu)
NZ (1) NZ290050A (hu)
PL (1) PL187064B1 (hu)
PT (1) PT804182E (hu)
RO (1) RO120041B1 (hu)
RU (1) RU2168982C2 (hu)
SK (1) SK283711B6 (hu)
WO (1) WO1996003122A2 (hu)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5712158A (en) * 1995-06-06 1998-01-27 Warner-Lambert Company Cell line for the rapid expression of functional calcium channels
US6372792B1 (en) 1996-04-26 2002-04-16 Guy Chouinard Method for treating anxiety, anxiety disorders and insomnia
BR9710536A (pt) 1996-07-24 1999-08-17 Warner Lambert Co Isobutilgaba e seus derivados para o tratamento da dor
CN1303059C (zh) 1997-10-27 2007-03-07 沃尼尔·朗伯公司 作为药物的环状氨基酸及其衍生物
EP1082306A1 (en) 1998-05-26 2001-03-14 Warner-Lambert Company Conformationally constrained amino acid compounds having affinity for the alpha2delta subunit of a calcium channel
FR2781793B1 (fr) * 1998-08-03 2001-07-20 Prographarm Lab Procede de fabrication de granules de gabapentine enrobes
JP2003512602A (ja) * 1999-09-16 2003-04-02 ワーナー−ランバート・カンパニー α2δ−1サブユニット結合リガンドのスクリーニング方法
RU2377234C2 (ru) * 2003-09-17 2009-12-27 Ксенопорт, Инк. Лечение или предупреждение синдрома беспокойных ног с использованием пролекарств аналогов гамк

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2016465A1 (en) * 1989-06-02 1990-12-02 Zola Phillip Horovitz Method for preventing or treating anxiety employing a calcium channel blocker
US5189026A (en) * 1991-06-07 1993-02-23 Fractal Laboratories, Inc. Treatment of human diseases involving dysregulation or dysfunction of the nervous system
RU94046105A (ru) * 1992-05-20 1997-06-20 Нортвестерн Юниверсити (Us) АНАЛОГИ γ -АМИНОМАСЛЯНОЙ КИСЛОТЫ И L-ГЛУТАМИНОВОЙ КИСЛОТЫ И СПОСОБЫ ИХ ПОЛУЧЕНИЯ

Also Published As

Publication number Publication date
HUT76835A (en) 1997-11-28
PL318268A1 (en) 1997-05-26
ATE218334T1 (de) 2002-06-15
CA2193384A1 (en) 1996-02-08
HU0102040D0 (en) 2001-07-30
HU0102041D0 (en) 2001-07-30
NZ290050A (en) 1999-08-30
RO120041B1 (ro) 2005-08-30
EP0804182B1 (en) 2002-06-05
JPH10503490A (ja) 1998-03-31
AU3006995A (en) 1996-02-22
SK283711B6 (sk) 2003-12-02
PL187064B1 (pl) 2004-05-31
RU2168982C2 (ru) 2001-06-20
CA2193384C (en) 2002-03-19
CZ16297A3 (en) 1997-07-16
PT804182E (pt) 2002-10-31
DE69526972T2 (de) 2002-11-21
CZ291757B6 (cs) 2003-05-14
WO1996003122A3 (en) 1996-07-18
SK9097A3 (en) 1998-05-06
AU703428B2 (en) 1999-03-25
DK0804182T3 (da) 2002-09-09
WO1996003122A2 (en) 1996-02-08
MX9606674A (es) 1997-03-29
ES2176334T3 (es) 2002-12-01
DE69526972D1 (de) 2002-07-11
HU223841B1 (hu) 2005-02-28
EP0804182A2 (en) 1997-11-05

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