HRP970081B1 - Substituted thiophenylalkenylcarbonylguanidides, method for their preparation, their use as medicinal or diagnostic agent as well as medicament containing them - Google Patents

Substituted thiophenylalkenylcarbonylguanidides, method for their preparation, their use as medicinal or diagnostic agent as well as medicament containing them

Info

Publication number
HRP970081B1
HRP970081B1 HR970081A HRP970081A HRP970081B1 HR P970081 B1 HRP970081 B1 HR P970081B1 HR 970081 A HR970081 A HR 970081A HR P970081 A HRP970081 A HR P970081A HR P970081 B1 HRP970081 B1 HR P970081B1
Authority
HR
Croatia
Prior art keywords
thiophenylalkenylcarbonylguanidides
medicinal
substituted
preparation
well
Prior art date
Application number
HR970081A
Other languages
English (en)
Inventor
Jan-Robert Schwark
Joachim Brendel
Heinz-Werner Kleemann
Hans-Jochen Lang
Andreas Weichert
Udo Albus
Wolfgang Scholz
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of HRP970081A2 publication Critical patent/HRP970081A2/hr
Publication of HRP970081B1 publication Critical patent/HRP970081B1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/28—Halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/30—Hetero atoms other than halogen
    • C07D333/34—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
HR970081A 1996-02-15 1997-02-13 Substituted thiophenylalkenylcarbonylguanidides, method for their preparation, their use as medicinal or diagnostic agent as well as medicament containing them HRP970081B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19605610A DE19605610A1 (de) 1996-02-15 1996-02-15 Substituierte Thiophenylalkenylcarbonsäureguanidide, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament

Publications (2)

Publication Number Publication Date
HRP970081A2 HRP970081A2 (en) 1998-04-30
HRP970081B1 true HRP970081B1 (en) 2003-04-30

Family

ID=7785491

Family Applications (1)

Application Number Title Priority Date Filing Date
HR970081A HRP970081B1 (en) 1996-02-15 1997-02-13 Substituted thiophenylalkenylcarbonylguanidides, method for their preparation, their use as medicinal or diagnostic agent as well as medicament containing them

Country Status (29)

Country Link
US (1) US5756535A (xx)
EP (1) EP0790245B1 (xx)
JP (1) JP4402747B2 (xx)
KR (1) KR970061887A (xx)
AR (1) AR005812A1 (xx)
AT (1) ATE202096T1 (xx)
AU (1) AU706554B2 (xx)
BR (1) BR9700990A (xx)
CA (1) CA2197628C (xx)
CZ (1) CZ45597A3 (xx)
DE (2) DE19605610A1 (xx)
DK (1) DK0790245T3 (xx)
ES (1) ES2158383T3 (xx)
GR (1) GR3036122T3 (xx)
HR (1) HRP970081B1 (xx)
HU (1) HUP9700437A3 (xx)
ID (1) ID15889A (xx)
IL (1) IL120214A (xx)
MX (1) MX9701163A (xx)
NO (1) NO315424B1 (xx)
NZ (1) NZ314230A (xx)
PL (1) PL318412A1 (xx)
PT (1) PT790245E (xx)
RU (1) RU2193033C2 (xx)
SI (1) SI0790245T1 (xx)
SK (1) SK282440B6 (xx)
TR (1) TR199700109A2 (xx)
TW (1) TW445261B (xx)
ZA (1) ZA971260B (xx)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19634229A1 (de) * 1996-08-23 1998-02-26 Basf Ag Photostabile UV-A-Filter enthaltende kosmetische Zubereitungen
US6011059A (en) * 1997-12-24 2000-01-04 Bristol-Myers Squibb Company Acyl guanidine sodium/proton exchange inhibitors and method
US6160134A (en) * 1997-12-24 2000-12-12 Bristol-Myers Squibb Co. Process for preparing chiral cyclopropane carboxylic acids and acyl guanidines
AU4360200A (en) 1999-04-23 2000-11-10 Bristol-Myers Squibb Company Bicyclic acyl guanidine sodium/proton exchange inhibitors and method
BRPI0213393B8 (pt) 2001-10-19 2021-05-25 Fujifilm Toyama Chemical Co Ltd derivados de éter alquílico, ou um de seus sais, processo para produzir um derivado de éter alquílico, derivado de alquil-amida, ou um de seus sais, e, composição farmacêutica

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2734904A (en) * 1956-02-14 Xcxnhxc-nh
US4544670A (en) * 1982-08-24 1985-10-01 William H. Rorer, Inc. Method of treating coccidiosis with acyl guanidines
DE4402057A1 (de) * 1994-01-25 1995-08-03 Hoechst Ag Perfluoralkylgruppen tragende phenyl-substituierte Alkylcarbonsäure-guanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
TW415937B (en) * 1994-01-25 2000-12-21 Hoechst Ag Phenyl-substituted alkylcarboxylic acid guanidides bearing perfluoroalkyl groups, process for their preparation, their use as a medicament or diagnostic, and medicament containing them
DE4412334A1 (de) * 1994-04-11 1995-10-19 Hoechst Ag Substituierte N-Heteroaroylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
DE4421536A1 (de) * 1994-06-20 1995-12-21 Hoechst Ag Perfluoralkylgruppen tragende phenylsubstituierte Alkenylcarbonsäure-guanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament

Also Published As

Publication number Publication date
TR199700109A2 (tr) 1997-09-21
AU706554B2 (en) 1999-06-17
MX9701163A (es) 1997-08-30
PT790245E (pt) 2001-10-30
EP0790245A1 (de) 1997-08-20
IL120214A0 (en) 1997-06-10
NO315424B1 (no) 2003-09-01
ATE202096T1 (de) 2001-06-15
DE19605610A1 (de) 1997-08-21
EP0790245B1 (de) 2001-06-13
HUP9700437A2 (hu) 1998-08-28
CZ45597A3 (en) 1997-09-17
GR3036122T3 (en) 2001-09-28
TW445261B (en) 2001-07-11
BR9700990A (pt) 1998-09-01
RU2193033C2 (ru) 2002-11-20
HRP970081A2 (en) 1998-04-30
SI0790245T1 (en) 2001-08-31
JP4402747B2 (ja) 2010-01-20
SK282440B6 (sk) 2002-02-05
AU1265997A (en) 1997-08-21
PL318412A1 (en) 1997-08-18
IL120214A (en) 2000-08-31
ZA971260B (en) 1997-08-15
ES2158383T3 (es) 2001-09-01
DK0790245T3 (da) 2001-09-03
CA2197628A1 (en) 1997-08-16
ID15889A (id) 1997-08-14
NO970697D0 (no) 1997-02-14
US5756535A (en) 1998-05-26
DE59703746D1 (de) 2001-07-19
HU9700437D0 (en) 1997-04-28
KR970061887A (ko) 1997-09-12
CA2197628C (en) 2006-05-16
NZ314230A (en) 1997-12-19
JPH09249660A (ja) 1997-09-22
HUP9700437A3 (en) 2000-03-28
SK21397A3 (en) 1997-09-10
AR005812A1 (es) 1999-07-14
NO970697L (no) 1997-08-18

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Legal Events

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A1OB Publication of a patent application
AIPI Request for the grant of a patent on the basis of a substantive examination of a patent application
ODRP Renewal fee for the maintenance of a patent

Payment date: 20030327

Year of fee payment: 7

B1PR Patent granted
PBON Lapse due to non-payment of renewal fee

Effective date: 20040214