HRP940710B1 - A novel antibiotic, balhimycin, a process for its production and its use as pharmaceutical - Google Patents

A novel antibiotic, balhimycin, a process for its production and its use as pharmaceutical

Info

Publication number
HRP940710B1
HRP940710B1 HRP940710A HRP940710B1 HR P940710 B1 HRP940710 B1 HR P940710B1 HR P940710 A HRP940710 A HR P940710A HR P940710 B1 HRP940710 B1 HR P940710B1
Authority
HR
Croatia
Prior art keywords
balhimycin
pharmaceutical
production
novel antibiotic
novel
Prior art date
Application number
Other languages
English (en)
Inventor
Suresh Nadkarni
Sugata Chatterjee
Mahesh Vithalbhai Patel
Kalyanapuram Rajagopal Desikan
Erra Koteswara Sat Vijayakumar
Bimal Naaresh Ganguli
Juergen Blumbach
Hans-Wolfram Fehlhaber
Herbert Kogler
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of HRP940710A2 publication Critical patent/HRP940710A2/hr
Publication of HRP940710B1 publication Critical patent/HRP940710B1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K4/00Peptides having up to 20 amino acids in an undefined or only partially defined sequence; Derivatives thereof
    • C07K4/04Peptides having up to 20 amino acids in an undefined or only partially defined sequence; Derivatives thereof from bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C12P1/04Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using bacteria
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C12P1/06Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using actinomycetales
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/04Actinomyces

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Mycology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines Containing Plant Substances (AREA)
HRP-1284/91 1990-07-27 1994-10-20 A novel antibiotic, balhimycin, a process for its production and its use as pharmaceutical HRP940710B1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP90114471 1990-07-27
EP90119883 1990-10-17
YU128491A YU48601B (sh) 1990-07-27 1991-07-22 Postupak za dobijanje novog antibiotika balhimycina

Publications (2)

Publication Number Publication Date
HRP940710A2 HRP940710A2 (en) 1997-06-30
HRP940710B1 true HRP940710B1 (en) 2001-02-28

Family

ID=26125378

Family Applications (1)

Application Number Title Priority Date Filing Date
HRP-1284/91 HRP940710B1 (en) 1990-07-27 1994-10-20 A novel antibiotic, balhimycin, a process for its production and its use as pharmaceutical

Country Status (23)

Country Link
EP (1) EP0468504B1 (de)
JP (1) JP3119680B2 (de)
KR (1) KR100221687B1 (de)
AT (1) ATE159261T1 (de)
AU (1) AU648570B2 (de)
CA (1) CA2047997C (de)
CY (1) CY2114B1 (de)
CZ (1) CZ282296B6 (de)
DE (1) DE69127935T2 (de)
DK (1) DK0468504T3 (de)
ES (1) ES2108022T3 (de)
FI (1) FI101402B (de)
GR (1) GR3025433T3 (de)
HR (1) HRP940710B1 (de)
HU (1) HU215146B (de)
IE (1) IE912643A1 (de)
IL (1) IL98958A0 (de)
IN (1) IN171883B (de)
NO (1) NO305132B1 (de)
NZ (1) NZ239130A (de)
PT (1) PT98444B (de)
RU (1) RU2043418C1 (de)
YU (1) YU48601B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5721208A (en) * 1991-06-29 1998-02-24 Hoechst Aktiengesellschaft Glycopeptides a process for their preparation and their use
TW213468B (de) * 1991-06-29 1993-09-21 Hoechst Ag
DE19523394A1 (de) * 1995-06-28 1997-01-09 Hoechst Ag Verwendung von Balhimycin zur Leistungssteigerung bei Tieren sowie leistungssteigernde Mittel
US6509177B1 (en) 1999-02-03 2003-01-21 Biogal Gyogyszergyar Rt. Process for the preparation of pseudomonic acid A antibiotic by microbiological method
DE19926770A1 (de) 1999-06-11 2000-12-14 Basf Ag Nukleinsäurefragment und Vektor, enthaltend eine Halogenase, sowie ein Verfahren zur Halogenierung chemischer Verbindungen

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3067099A (en) * 1955-09-16 1962-12-04 Lilly Co Eli Vancomycin and method for its preparation

Also Published As

Publication number Publication date
ATE159261T1 (de) 1997-11-15
PT98444B (pt) 1999-01-29
NO912931L (no) 1992-01-28
IN171883B (de) 1993-01-30
YU128491A (sh) 1994-12-28
FI913569A0 (fi) 1991-07-25
CA2047997C (en) 2002-04-30
RU2043418C1 (ru) 1995-09-10
JP3119680B2 (ja) 2000-12-25
HRP940710A2 (en) 1997-06-30
EP0468504B1 (de) 1997-10-15
HU215146B (hu) 2000-03-28
JPH04261200A (ja) 1992-09-17
AU8145391A (en) 1992-01-30
ES2108022T3 (es) 1997-12-16
IL98958A0 (en) 1992-07-15
FI101402B1 (fi) 1998-06-15
KR100221687B1 (ko) 1999-10-01
DE69127935D1 (de) 1997-11-20
AU648570B2 (en) 1994-04-28
CA2047997A1 (en) 1992-01-28
YU48601B (sh) 1998-12-23
GR3025433T3 (en) 1998-02-27
PT98444A (pt) 1992-05-29
NO305132B1 (no) 1999-04-06
EP0468504A1 (de) 1992-01-29
CS233491A3 (en) 1992-03-18
DK0468504T3 (da) 1998-06-02
CY2114B1 (en) 2002-04-26
NZ239130A (en) 1993-09-27
IE912643A1 (en) 1992-01-29
HU912516D0 (en) 1992-01-28
HUT61606A (en) 1993-01-28
DE69127935T2 (de) 1998-03-19
FI913569A (fi) 1992-01-28
CZ282296B6 (cs) 1997-06-11
KR920002795A (ko) 1992-02-28
FI101402B (fi) 1998-06-15
NO912931D0 (no) 1991-07-26

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Legal Events

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A1OB Publication of a patent application
AIPI Request for the grant of a patent on the basis of a substantive examination of a patent application
B1PR Patent granted
ODRP Renewal fee for the maintenance of a patent

Payment date: 20020722

Year of fee payment: 12

PBON Lapse due to non-payment of renewal fee

Effective date: 20030723