HRP940251B1 - Process for the preparation of azithromycin dihydrochloride - Google Patents

Process for the preparation of azithromycin dihydrochloride

Info

Publication number
HRP940251B1
HRP940251B1 HR940251A HRP940251A HRP940251B1 HR P940251 B1 HRP940251 B1 HR P940251B1 HR 940251 A HR940251 A HR 940251A HR P940251 A HRP940251 A HR P940251A HR P940251 B1 HRP940251 B1 HR P940251B1
Authority
HR
Croatia
Prior art keywords
preparation
azithromycin
dihydrochloride
azithromycin dihydrochloride
broad
Prior art date
Application number
HR940251A
Other languages
English (en)
Inventor
Stjepan Mutak
Original Assignee
Stjepan Mutak
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Stjepan Mutak filed Critical Stjepan Mutak
Priority to HR940251A priority Critical patent/HRP940251B1/xx
Priority to CA002146475A priority patent/CA2146475C/en
Priority to DE69500327T priority patent/DE69500327T2/de
Priority to EP95105285A priority patent/EP0677530B1/de
Priority to AT95105285T priority patent/ATE154028T1/de
Priority to ES95105285T priority patent/ES2104441T3/es
Priority to RO95-00700A priority patent/RO113737B1/ro
Priority to UA95048323A priority patent/UA41902C2/uk
Priority to PL95308095A priority patent/PL177292B1/pl
Priority to SI9500124A priority patent/SI9500124A/sl
Priority to SK491-95A priority patent/SK281178B6/sk
Priority to JP07088166A priority patent/JP3075681B2/ja
Priority to CN95104228A priority patent/CN1042033C/zh
Priority to HU9501084A priority patent/HU217553B/hu
Priority to RU95105596A priority patent/RU2134271C1/ru
Priority to BG99580A priority patent/BG61769B1/bg
Publication of HRP940251A2 publication Critical patent/HRP940251A2/hr
Publication of HRP940251B1 publication Critical patent/HRP940251B1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
HR940251A 1994-04-15 1994-04-15 Process for the preparation of azithromycin dihydrochloride HRP940251B1 (en)

Priority Applications (16)

Application Number Priority Date Filing Date Title
HR940251A HRP940251B1 (en) 1994-04-15 1994-04-15 Process for the preparation of azithromycin dihydrochloride
CA002146475A CA2146475C (en) 1994-04-15 1995-04-06 Process for the preparation of azithromycin dihydrochloride
DE69500327T DE69500327T2 (de) 1994-04-15 1995-04-07 Verfahren zur Herstellung von azithromycin Dihydrochloriden
EP95105285A EP0677530B1 (de) 1994-04-15 1995-04-07 Verfahren zur Herstellung von azithromycin Dihydrochloriden
AT95105285T ATE154028T1 (de) 1994-04-15 1995-04-07 Verfahren zur herstellung von azithromycin dihydrochloriden
ES95105285T ES2104441T3 (es) 1994-04-15 1995-04-07 Procedimiento para la preparacion de diclorhidrato de azitromicina.
RO95-00700A RO113737B1 (ro) 1994-04-15 1995-04-11 Procedeu de obtinere a diclorhidratului de azitromicina
UA95048323A UA41902C2 (uk) 1994-04-15 1995-04-11 Спосіб одержання дигідрохлориду азитроміцину
PL95308095A PL177292B1 (pl) 1994-04-15 1995-04-12 Sposób wytwarzania dwuchlorowodorku azytromycyny
SI9500124A SI9500124A (en) 1994-04-15 1995-04-13 Process for the preparation of Azithromycin Dihydrochloride
SK491-95A SK281178B6 (sk) 1994-04-15 1995-04-13 Spôsob prípravy dihydrochloridu azitromycínu
JP07088166A JP3075681B2 (ja) 1994-04-15 1995-04-13 アジスロマイシン二塩酸塩の製造方法
CN95104228A CN1042033C (zh) 1994-04-15 1995-04-13 阿齐霉素二盐酸盐的制备方法
HU9501084A HU217553B (hu) 1994-04-15 1995-04-14 Eljárás azitromicin-dihidroklorid előállítására
RU95105596A RU2134271C1 (ru) 1994-04-15 1995-04-14 Способ получения дигидрохлорида азитромицина
BG99580A BG61769B1 (bg) 1994-04-15 1995-04-14 Метод за получаване на азитромицин дихидрохлорид

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HR940251A HRP940251B1 (en) 1994-04-15 1994-04-15 Process for the preparation of azithromycin dihydrochloride

Publications (2)

Publication Number Publication Date
HRP940251A2 HRP940251A2 (en) 1997-06-30
HRP940251B1 true HRP940251B1 (en) 1998-12-31

Family

ID=10946105

Family Applications (1)

Application Number Title Priority Date Filing Date
HR940251A HRP940251B1 (en) 1994-04-15 1994-04-15 Process for the preparation of azithromycin dihydrochloride

Country Status (16)

Country Link
EP (1) EP0677530B1 (de)
JP (1) JP3075681B2 (de)
CN (1) CN1042033C (de)
AT (1) ATE154028T1 (de)
BG (1) BG61769B1 (de)
CA (1) CA2146475C (de)
DE (1) DE69500327T2 (de)
ES (1) ES2104441T3 (de)
HR (1) HRP940251B1 (de)
HU (1) HU217553B (de)
PL (1) PL177292B1 (de)
RO (1) RO113737B1 (de)
RU (1) RU2134271C1 (de)
SI (1) SI9500124A (de)
SK (1) SK281178B6 (de)
UA (1) UA41902C2 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HRP20020231A2 (en) 2002-03-18 2003-12-31 Pliva D D ISOSTRUCTURAL PSEUDOPOLYMORPHS OF 9-DEOXO-9a-AZA-9a-METHYL-9a-HOMOERYTHROMYCIN A
US6861411B1 (en) 1997-12-02 2005-03-01 Pfizer, Inc. Method of treating eye infections with azithromycin
US7056893B2 (en) 1999-03-31 2006-06-06 Insite Vision, Inc. Topical treatment for prevention of ocular infections
US6239113B1 (en) 1999-03-31 2001-05-29 Insite Vision, Incorporated Topical treatment or prevention of ocular infections
US7572773B2 (en) 2003-07-24 2009-08-11 Pliva Hrvatska D.O.O. Single dose fast dissolving azithromycin
CN100343267C (zh) * 2005-08-05 2007-10-17 新昌国邦化学工业有限公司 阿奇霉素酒石酸盐的制备方法
CN100427499C (zh) * 2005-12-20 2008-10-22 山东诚创医药技术开发有限公司 一种阿奇霉素的可溶性盐及其制备方法
CN101092440B (zh) * 2007-07-19 2010-05-26 浙江尖峰药业有限公司 硫酸阿奇霉素的制备方法
CN102746350A (zh) * 2011-04-21 2012-10-24 常州泰康制药有限公司 盐酸阿奇霉素的制备方法
CN104045674B (zh) * 2014-05-21 2017-01-04 丽珠医药集团股份有限公司 一种阿奇霉素的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1100504A (en) * 1967-08-16 1968-01-24 Pliva Pharm & Chem Works Erythromycin oxime and 9-amino-3-o-cladinosyl-5-o-desosaminyl-6,11,12-trihydroxy-2,4,6,8,10,12-hexamethylpentadecane-13-olide
US4474768A (en) * 1982-07-19 1984-10-02 Pfizer Inc. N-Methyl 11-aza-10-deoxo-10-dihydro-erytromycin A, intermediates therefor
YU43658B (en) * 1983-07-18 1989-10-31 Pliva Pharm & Chem Works Process for preparing 7,16-dioxa-2-aza-10-0-cladinosyl-12,0-desosaminyl-4,5-dihydroxy-6-ethyl-3,5,9,11,13,15-hexamethyl-bicyclo(11.2.1)hexadeca-1(2)-ene-8

Also Published As

Publication number Publication date
ATE154028T1 (de) 1997-06-15
BG99580A (bg) 1995-12-29
BG61769B1 (bg) 1998-05-29
EP0677530B1 (de) 1997-06-04
ES2104441T3 (es) 1997-10-01
JP3075681B2 (ja) 2000-08-14
HU9501084D0 (en) 1995-06-28
HU217553B (hu) 2000-02-28
HRP940251A2 (en) 1997-06-30
SK281178B6 (sk) 2000-12-11
DE69500327T2 (de) 1998-01-08
CN1042033C (zh) 1999-02-10
UA41902C2 (uk) 2001-10-15
PL177292B1 (pl) 1999-10-29
EP0677530A1 (de) 1995-10-18
SK49195A3 (en) 1995-11-08
RU2134271C1 (ru) 1999-08-10
HUT71840A (en) 1996-02-28
RO113737B1 (ro) 1998-10-30
JPH0841058A (ja) 1996-02-13
RU95105596A (ru) 1997-01-10
DE69500327D1 (de) 1997-07-10
SI9500124A (en) 1995-10-31
CA2146475C (en) 1999-06-29
CN1112566A (zh) 1995-11-29
PL308095A1 (en) 1995-10-16
CA2146475A1 (en) 1995-10-16

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Effective date: 20050416