HRP931429B1 - Process for the preparation of amlodipin benzensulphonate - Google Patents

Process for the preparation of amlodipin benzensulphonate

Info

Publication number
HRP931429B1
HRP931429B1 HRP-9200344A HRP931429A HRP931429B1 HR P931429 B1 HRP931429 B1 HR P931429B1 HR P931429 A HRP931429 A HR P931429A HR P931429 B1 HRP931429 B1 HR P931429B1
Authority
HR
Croatia
Prior art keywords
benzensulphonate
amlodipin
preparation
amlodipin benzensulphonate
Prior art date
Application number
HRP-9200344A
Other languages
English (en)
Inventor
Borut Furlan
Anton Opar
Alenka Jeriha
Original Assignee
Lek Tovarna Farmacevtskih
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lek Tovarna Farmacevtskih filed Critical Lek Tovarna Farmacevtskih
Publication of HRP931429A2 publication Critical patent/HRP931429A2/hr
Publication of HRP931429B1 publication Critical patent/HRP931429B1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
HRP-9200344A 1992-11-26 1993-11-23 Process for the preparation of amlodipin benzensulphonate HRP931429B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SI9200344A SI9200344B (sl) 1992-11-26 1992-11-26 Postopek za pripravo amlodipin benzensulfonata

Publications (2)

Publication Number Publication Date
HRP931429A2 HRP931429A2 (en) 1995-12-31
HRP931429B1 true HRP931429B1 (en) 1997-10-31

Family

ID=20431051

Family Applications (1)

Application Number Title Priority Date Filing Date
HRP-9200344A HRP931429B1 (en) 1992-11-26 1993-11-23 Process for the preparation of amlodipin benzensulphonate

Country Status (9)

Country Link
EP (1) EP0599220B1 (sl)
CZ (1) CZ283041B6 (sl)
DE (1) DE69304020T2 (sl)
FI (1) FI103042B (sl)
HR (1) HRP931429B1 (sl)
PL (2) PL173645B1 (sl)
RU (1) RU2105759C1 (sl)
SI (1) SI9200344B (sl)
SK (1) SK279353B6 (sl)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU221810B1 (hu) * 1997-08-12 2003-01-28 EGIS Gyógyszergyár Rt. Eljárás amlodipin-bezilát előállítására és az eljárás intermedierjei
UA72768C2 (en) * 1999-07-05 2005-04-15 Richter Gedeon Vegyeszet A method for obtaining amilodipine benzenesulphonate
ATE454890T1 (de) * 2001-07-06 2010-01-15 Lek Pharmaceuticals Verfahren zur herstellung hochreines amlodipinbenzolsulfonat
US6680334B2 (en) 2001-08-28 2004-01-20 Pfizer Inc Crystalline material
US6828339B2 (en) * 2001-11-21 2004-12-07 Synthon Bv Amlodipine salt forms and processes for preparing them
SI21233A (sl) * 2002-05-31 2003-12-31 LEK, tovarna farmacevtskih in kemičnih izdelkov, d.d. Kristalni hidratni obliki amlodipin benzensulfonata visoke čistote, postopki za njuno pripravo in uporaba
US6784297B2 (en) 2002-09-04 2004-08-31 Kopran Limited Process for the preparation of anti-ischemic and anti-hypertensive drug amlodipine besylate
EP1407773A1 (en) * 2002-10-08 2004-04-14 Council of Scientific and Industrial Research A process for the preparation of s (-) amlodipine salts
WO2004058711A1 (en) * 2002-12-30 2004-07-15 Eos Eczacibasi Ozgun Kimyasal Urunler Sanayi Ve Ticaret A.S. Isolation of dihydropyridine derivative and preparation salts thereof
JP4539862B2 (ja) 2003-03-28 2010-09-08 日産化学工業株式会社 Ｔ型カルシウムチャネル阻害剤
WO2007131759A1 (en) * 2006-05-15 2007-11-22 Lek Pharmaceuticals D.D. A process for the preparation of amlodipine benzenesulfonate
RS53688B9 (sr) 2008-07-08 2020-01-31 Incyte Holdings Corp 1,2,5-oksadiazoli kao inhibitori indoleamin 2,3-dioksigenaze
SG171722A1 (en) 2008-12-22 2011-07-28 Pola Chem Ind Inc Melanin production inhibitor
CN102516159B (zh) * 2011-12-15 2013-10-09 扬子江药业集团江苏海慈生物药业有限公司 一种苯磺酸左旋氨氯地平的生产方法
EP2911669B1 (en) 2012-10-26 2024-04-10 The University of Chicago Synergistic combination of immunologic inhibitors for the treatment of cancer

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK161312C (da) * 1982-03-11 1991-12-09 Pfizer Analogifremgangsmaade til fremstilling af 2-aminoalkoxymethyl-4-phenyl-6-methyl-1,4-dihydropyridin-3,5-dicarboxylsyreestere eller syreadditionssalte deraf samt phthalimidoderivater til anvendelse som udgangsmateriale ved fremgangsmaaden
GB8608335D0 (en) * 1986-04-04 1986-05-08 Pfizer Ltd Pharmaceutically acceptable salts
EP0352863A3 (en) * 1988-07-29 1990-08-22 ZAMBON GROUP S.p.A. 1,4-dihydropyridine dicarboxylic acid derivatives

Also Published As

Publication number Publication date
EP0599220B1 (en) 1996-08-14
FI103042B1 (fi) 1999-04-15
FI934882A0 (fi) 1993-11-04
DE69304020D1 (de) 1996-09-19
FI103042B (fi) 1999-04-15
EP0599220A1 (en) 1994-06-01
CZ283041B6 (cs) 1997-12-17
FI934882A (fi) 1994-05-27
PL173645B1 (pl) 1998-04-30
CZ216593A3 (en) 1994-06-15
PL301080A1 (en) 1994-05-30
SI9200344A (en) 1994-06-30
SK112593A3 (en) 1994-11-09
SK279353B6 (sk) 1998-10-07
RU2105759C1 (ru) 1998-02-27
SI9200344B (sl) 1998-06-30
DE69304020T2 (de) 1997-03-06
HRP931429A2 (en) 1995-12-31
PL174647B1 (pl) 1998-08-31

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Legal Events

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B1PR Patent granted
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Payment date: 20111117

Year of fee payment: 19

PBON Lapse due to non-payment of renewal fee

Effective date: 20121124