HRP930957A2 - Novel biologically active eburnamenine derivatives, maceutical compositions containing them and process for aring the same - Google Patents

Novel biologically active eburnamenine derivatives, maceutical compositions containing them and process for aring the same

Info

Publication number
HRP930957A2
HRP930957A2 HR930957A HRP930957A HRP930957A2 HR P930957 A2 HRP930957 A2 HR P930957A2 HR 930957 A HR930957 A HR 930957A HR P930957 A HRP930957 A HR P930957A HR P930957 A2 HRP930957 A2 HR P930957A2
Authority
HR
Croatia
Prior art keywords
aring
same
biologically active
compositions containing
novel biologically
Prior art date
Application number
HR930957A
Other languages
English (en)
Inventor
Zoltan Tuba
Sandor Maho
Aniko Gere
Pal Vittay
Bela Kiss
Eva Palosi
Laszlo Szporny
Csaba Szantay
Ferenc Soti
Nee Kardos Zsuzsa Balogh
Maria Incze
Gabor Balogh
Maria Gazdag
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Publication of HRP930957A2 publication Critical patent/HRP930957A2/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D461/00Heterocyclic compounds containing indolo [3,2,1-d,e] pyrido [3,2,1,j] [1,5]-naphthyridine ring systems, e.g. vincamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Neurology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Steroid Compounds (AREA)
HR930957A 1992-06-09 1993-06-08 Novel biologically active eburnamenine derivatives, maceutical compositions containing them and process for aring the same HRP930957A2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU9201911A HU209678B (en) 1992-06-09 1992-06-09 Process for producing biologically active eburnamenin-14-carbonyl-amino derivatives and pharmaceutical compositions containing them

Publications (1)

Publication Number Publication Date
HRP930957A2 true HRP930957A2 (en) 1995-02-28

Family

ID=10982021

Family Applications (1)

Application Number Title Priority Date Filing Date
HR930957A HRP930957A2 (en) 1992-06-09 1993-06-08 Novel biologically active eburnamenine derivatives, maceutical compositions containing them and process for aring the same

Country Status (18)

Country Link
US (1) US5510345A (sl)
EP (1) EP0644885A1 (sl)
JP (1) JPH07507793A (sl)
KR (1) KR950701924A (sl)
AU (1) AU4352493A (sl)
CA (1) CA2136547A1 (sl)
CZ (1) CZ307994A3 (sl)
EE (1) EE9400070A (sl)
FI (1) FI945780A (sl)
GR (1) GR1001597B (sl)
HR (1) HRP930957A2 (sl)
HU (1) HU209678B (sl)
IL (1) IL105942A0 (sl)
LT (1) LT3118B (sl)
NZ (1) NZ253308A (sl)
SI (1) SI9300309A (sl)
WO (1) WO1993025550A1 (sl)
ZA (1) ZA934037B (sl)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200626139A (en) 2004-09-20 2006-08-01 Xenon Pharmaceuticals Inc Heterocyclic derivatives and their use as therapeutic agents
CN101083992A (zh) 2004-09-20 2007-12-05 泽农医药公司 抑制人硬脂酰CoA去饱和酶的哒嗪衍生物
US7951805B2 (en) 2004-09-20 2011-05-31 Xenon Pharmaceuticals Inc. Heterocyclic derivatives and their use as mediators of stearoyl-CoA desaturase
CA2580856A1 (en) 2004-09-20 2006-03-30 Xenon Pharmaceuticals Inc. Heterocyclic derivatives and their use as stearoyl-coa desaturase inhibitors
AU2005286647A1 (en) 2004-09-20 2006-03-30 Xenon Pharmaceuticals Inc. Heterocyclic derivatives and their use as stearoyl-CoA desaturase inhibitors
BRPI0515483A (pt) 2004-09-20 2008-07-22 Xenon Pharmaceuticals Inc derivados heterocìclicos para o tratamento de doenças mediadas por enzimas estearoil-coa desaturase
EP1799667B1 (en) 2004-09-20 2013-03-20 Xenon Pharmaceuticals Inc. Heterocyclic derivatives and their use as therapeutic agents
JP2008538544A (ja) * 2004-09-23 2008-10-30 レディ ユーエス セラピューティックス, インコーポレイテッド 新規ピリミジン化合物、それらの調製のためのプロセスおよびそれらを含む組成物
BRPI0611187A2 (pt) 2005-06-03 2010-08-24 Xenon Pharmaceuticals Inc derivados aminotiazàis como inibidores da estearoil-coa desaturase humana
EP2276750A2 (en) * 2008-03-27 2011-01-26 Auckland Uniservices Limited Substituted pyrimidines and triazines and their use in cancer therapy
CN101928286A (zh) * 2009-06-18 2010-12-29 谢开智 长春胺衍生物及制备方法
RU2737434C2 (ru) 2013-03-13 2020-11-30 Форма Терапьютикс, Инк. Новые соединения и композиции для ингибирования fasn
US10774064B2 (en) 2016-06-02 2020-09-15 Cadent Therapeutics, Inc. Potassium channel modulators
JP6997197B2 (ja) 2017-01-23 2022-01-17 カデント セラピューティクス,インコーポレーテッド カリウムチャネルモジュレーター
BR112021007552A2 (pt) 2018-10-22 2021-07-27 Cadent Therapeutics, Inc. formas cristalinas de moduladores de canal de potássio
WO2020092395A1 (en) 2018-10-29 2020-05-07 Forma Therapeutics, Inc. SOLID FORMS OF (4-(2-FLUORO-4-(1-METHYL-1 H-BENZO[d]IMIDAZOL-5-YL)BENZOYL) PIPERAZIN-1-YL)(1-HYDROXYCYCLOPROPYL)METHANONE

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2176516B1 (sl) * 1972-03-22 1975-03-14 Synthelabo
HU171663B (hu) * 1975-09-01 1978-02-28 Richter Gedeon Vegyeszet Sposob poluchenija novykh proizvodnykh 14-skobka-zamehhennogo metil-skobka zakryta-vinkana
US4547505A (en) * 1983-03-25 1985-10-15 Degussa Aktiengesellschaft N-Phenyl-N-'-cycloalkylalkanoylpiperazine useful as analgetics and process for its production
WO1987001706A2 (en) 1985-09-12 1987-03-26 The Upjohn Company C20 through c26 amino steroids
US5099019A (en) * 1985-09-12 1992-03-24 Upjohn Company Amines useful in producing pharmaceutically active CNS compounds
AU7580187A (en) 1986-06-23 1988-01-12 Upjohn Company, The Androstane-type and cortical aminoesters
AU1704588A (en) 1987-04-03 1988-11-02 Upjohn Company, The Amino-9,10-secosteroids
CA1338012C (en) 1987-04-27 1996-01-30 John Michael Mccall Pharmaceutically active amines
FR2644787B1 (fr) 1989-03-22 1995-02-03 Roussel Uclaf Nouveaux steroides 21 aminosubstitues, leur procede de preparation et les intermediaires de ce procede, leur application comme medicaments et les compositions pharmaceutiques les contenant
FR2644789B1 (fr) 1989-03-22 1995-02-03 Roussel Uclaf Nouveaux steroides 19-nor, 3-ceto comportant une chaine en 17 aminosubstituee, leur procede de preparation et les intermediaires de ce procede, leur application comme medicaments et les compositions pharmaceutiques les contenant
FR2644788B1 (fr) 1989-03-22 1995-02-03 Roussel Uclaf Nouveaux steroides 3-ceto comportant une chaine en 17 amino-substituee, leur procede de preparation et les intermediaires de ce procede, leur application comme medicaments et les compositions pharmaceutiques les contenant
CA2071000A1 (en) 1990-01-26 1991-07-27 John M. Mccall 5-oxygenated-2,4,6-triaminopyrimidines

Also Published As

Publication number Publication date
ZA934037B (en) 1994-01-06
WO1993025550A1 (en) 1993-12-23
CZ307994A3 (en) 1995-07-12
HU9201911D0 (en) 1992-09-28
KR950701924A (ko) 1995-05-17
US5510345A (en) 1996-04-23
LTIP599A (en) 1994-07-15
EP0644885A1 (en) 1995-03-29
CA2136547A1 (en) 1993-12-23
GR1001597B (el) 1994-06-30
LT3118B (en) 1994-12-27
FI945780A0 (fi) 1994-12-08
EE9400070A (et) 1995-12-15
HU209678B (en) 1994-10-28
JPH07507793A (ja) 1995-08-31
NZ253308A (en) 1995-11-27
IL105942A0 (en) 1993-10-20
SI9300309A (sl) 1993-12-31
FI945780A (fi) 1994-12-08
HUT64540A (en) 1994-01-28
AU4352493A (en) 1994-01-04

Similar Documents

Publication Publication Date Title
HUP9603495A3 (en) 1-phenyl-2-dimethylaminomethyl-cyclohexan-1-ol-compounds, pharmaceutical compositions containing the same and process for their preparation
IL112193A0 (en) Phenylpyrazolopyridine derivatives, processes for the preparation thereof and pharmaceutical compositions containing the same
IL109568A0 (en) Urea derivatives, pharmaceutical compositions containing the same and processes for the preparation thereof
HUT64734A (en) Anthraquinone-derivativdes, process for preparing them and pharmaceutical compositions containing them
NZ238288A (en) Pyrazolo- and triazolo-(1,3,5)triazine derivatives; processes and pharmaceutical compositions
IL98873A0 (en) Benzodiazepine derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
HRP930957A2 (en) Novel biologically active eburnamenine derivatives, maceutical compositions containing them and process for aring the same
IL105348A0 (en) Azabicyclo derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
HU9402292D0 (en) New baccatine-iii and 10-deacetyl-baccatine-iii derivatives, process for producing them and pharmaceutical compositions containing them as active component
IL107358A0 (en) a-Phosphonosulfonate derivatives, processes for the preparation thereof, and pharmaceutical compositions containing the same
IL97931A0 (en) Pyridazine derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
ZA911804B (en) 1-azabicyclic compounds,processes and pharmaceutical compositions containing them
HUP9603001A3 (en) Heterocycle compounds comprising nitrogen, process for producing them and pharmaceutical compositions containing the same
IL104471A0 (en) Imidazole derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
EP0638080A4 (en) PYRIMIDINE 7-BISUBSTITUEE-METHYL-4-OXO-3H -, 5H --PYRROLO 3,2-d -], PHARMACEUTICAL USE AND COMPOSITIONS CONTAINING SAID PYRIMIDINE.
GB9310075D0 (en) New mercapto-amide derivatives,processes for the preparation thereof and pharmaceutical composition comprising the same
HRP931016A2 (en) Thienothiazin derivatives, process for the preparation and application thereof
EP0572308A3 (fr) Dérivés hétérocycliques, leur procédé de préparation et les compositions qui les contiennent.
HU9303376D0 (en) Process for producing alpha, omega-diaryl-alkane derivatives and pharmaceutical compositions containing them
HUT63162A (en) Process for producing 1,4-benzodiazepine derivatives and pharmaceutical compositions comprising same
HUP9600061A2 (en) 3-alkoxycarbonyl-1,3,4-thiadiazin-2-on derivatives, process for their preparation and pharmaceutical compositions containing the same
IL106433A0 (en) Furylthiazole derivatives,processes for the preparation thereof and pharmaceutical composition containing the same
EP0583606A3 (en) New cardioactive hydrazono-5-beta, 14-beta-androstanes, process for their preparation and the pharmaceutical compositions containing them.
HU9401191D0 (en) 2-aminio-4-heteroaryl-1,4-dihidropyridines, process for producing them and pharmaceutical compositions containing them as active component
HU9401281D0 (en) Heterocyclic compounds, pharmaceutical compositions containing them, and process for producing the active components

Legal Events

Date Code Title Description
A1OB Publication of a patent application
ODBC Application rejected