HRP920903B1 - Indenoindole compounds and a process for preparing the same - Google Patents

Indenoindole compounds and a process for preparing the same

Info

Publication number
HRP920903B1
HRP920903B1 HRP-1223/90A HRP920903A HRP920903B1 HR P920903 B1 HRP920903 B1 HR P920903B1 HR P920903 A HRP920903 A HR P920903A HR P920903 B1 HRP920903 B1 HR P920903B1
Authority
HR
Croatia
Prior art keywords
lower alkyl
hydrogen
group
cor
alkyl group
Prior art date
Application number
HRP-1223/90A
Other languages
English (en)
Inventor
Howard G Shertzer
Original Assignee
Howard G. Shertzer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Howard G. Shertzer filed Critical Howard G. Shertzer
Publication of HRP920903A2 publication Critical patent/HRP920903A2/hr
Publication of HRP920903B1 publication Critical patent/HRP920903B1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/80[b, c]- or [b, d]-condensed
    • C07D209/94[b, c]- or [b, d]-condensed containing carbocyclic rings other than six-membered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/58[b]- or [c]-condensed
    • C07D209/70[b]- or [c]-condensed containing carbocyclic rings other than six-membered
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/06Free radical scavengers or antioxidants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Toxicology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biochemistry (AREA)
  • Psychology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
HRP-1223/90A 1989-06-22 1992-10-02 Indenoindole compounds and a process for preparing the same HRP920903B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE8902274A SE8902274D0 (sv) 1989-06-22 1989-06-22 Indenoidole compounds ii
YU122390A YU122390A (sh) 1989-06-22 1990-06-22 Indenoindolova jedinjenja ii

Publications (2)

Publication Number Publication Date
HRP920903A2 HRP920903A2 (hr) 1994-04-30
HRP920903B1 true HRP920903B1 (en) 1998-06-30

Family

ID=20376370

Family Applications (1)

Application Number Title Priority Date Filing Date
HRP-1223/90A HRP920903B1 (en) 1989-06-22 1992-10-02 Indenoindole compounds and a process for preparing the same

Country Status (34)

Country Link
EP (1) EP0409410B1 (hu)
JP (1) JP3064411B2 (hu)
KR (1) KR920702679A (hu)
CN (1) CN1033029C (hu)
AT (1) ATE135688T1 (hu)
BG (1) BG60317B2 (hu)
CA (1) CA2060897A1 (hu)
DD (1) DD297960A5 (hu)
DE (1) DE69025998T2 (hu)
DK (1) DK0409410T3 (hu)
DZ (1) DZ1428A1 (hu)
ES (1) ES2084660T3 (hu)
FI (1) FI100800B (hu)
GR (1) GR3019779T3 (hu)
HR (1) HRP920903B1 (hu)
HU (1) HUT59097A (hu)
IE (1) IE74682B1 (hu)
IL (1) IL94830A (hu)
IS (1) IS3590A7 (hu)
LT (1) LT3675B (hu)
LV (1) LV10253B (hu)
MX (1) MX21244A (hu)
MY (1) MY107311A (hu)
NO (1) NO177932C (hu)
NZ (1) NZ234175A (hu)
PL (1) PL167761B1 (hu)
PT (1) PT94468B (hu)
RO (1) RO111573B1 (hu)
RU (1) RU2104270C1 (hu)
SE (1) SE8902274D0 (hu)
SI (1) SI9011223B (hu)
WO (1) WO1990015799A1 (hu)
YU (1) YU122390A (hu)
ZA (1) ZA904827B (hu)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ240232A (en) * 1990-10-16 1994-05-26 Univ Bath Indenoindole derivatives and compositions thereof
JPH0656669A (ja) * 1992-06-11 1994-03-01 Asahi Breweries Ltd 活性酸素消去作用を持つプテリン誘導体製剤
SE9302431D0 (sv) * 1993-07-16 1993-07-16 Ab Astra Use of indenoindole compounds
CA2128283A1 (fr) * 1993-07-20 1995-01-21 Paul Caubere (thia)cycloalkyl¬b|indoles, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
US6288099B1 (en) 1998-12-04 2001-09-11 American Home Products Corporation Substituted benzofuranoindoles and indenoindoles as novel potassium channel openers
JP2002531569A (ja) * 1998-12-04 2002-09-24 ワイス 新規なカリウムチャンネル開放物質としての置換ベンゾフラノインドール及びインデノインドール
FR2826009B1 (fr) * 2001-06-13 2003-08-15 Servier Lab Nouveaux derives d'indenoindolones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
PL1910338T3 (pl) 2005-07-14 2011-02-28 Irm Llc Związki heterotetracykliczne jako mimetyki TPO
DE102006047231B4 (de) * 2006-10-04 2009-02-12 Hemmerling, Hans-Jörg, Dr. Substituierte Indeno[1,2-b]indolderivate als neue Hemmstoffe der Protein Kinase CK2 und ihre Verwendung als Tumor Therapeutika, Cytostatika und Diagnostika
AU2012270311B2 (en) * 2011-06-16 2016-04-21 Katholieke Universiteit Leuven K.U. Leuven R & D Indanone derivatives, pharmaceutically acceptable salts or optical isomers thereof, preparation method for same, and pharmaceutical compositions containing same as active ingredient for preventing or treating viral diseases
CN105121433B (zh) 2012-12-14 2018-01-23 韩国化学研究院 抗病毒化合物、其药学上可接受的盐或光学异构体、用于制备它们的方法以及包含它们作为有效成分的用于预防或治疗病毒性疾病的药物组合物

Also Published As

Publication number Publication date
SE8902274D0 (sv) 1989-06-22
MX21244A (es) 1994-03-31
HU904825D0 (en) 1992-03-30
LV10253A (lv) 1994-10-20
DD297960A5 (de) 1992-01-30
CN1051554A (zh) 1991-05-22
DZ1428A1 (fr) 2004-09-13
SI9011223B (sl) 1998-08-31
IL94830A0 (en) 1991-04-15
GR3019779T3 (en) 1996-07-31
MY107311A (en) 1995-11-30
CN1033029C (zh) 1996-10-16
YU122390A (sh) 1992-09-07
ZA904827B (en) 1991-04-24
HUT59097A (en) 1992-04-28
NO915049D0 (no) 1991-12-20
PL285752A1 (en) 1991-03-11
AU5836990A (en) 1991-01-08
JPH04505923A (ja) 1992-10-15
JP3064411B2 (ja) 2000-07-12
SI9011223A (en) 1997-10-31
PL167761B1 (pl) 1995-10-31
DK0409410T3 (da) 1996-04-29
ATE135688T1 (de) 1996-04-15
AU644084B2 (en) 1993-12-02
IL94830A (en) 1996-07-23
PT94468A (pt) 1991-02-08
IS3590A7 (is) 1990-12-23
ES2084660T3 (es) 1996-05-16
LT3675B (en) 1996-01-25
NO177932B (no) 1995-09-11
LV10253B (en) 1995-04-20
RO111573B1 (ro) 1996-11-29
KR920702679A (ko) 1992-10-06
IE74682B1 (en) 1997-07-30
BG60317B2 (bg) 1994-07-25
LTIP912A (en) 1995-03-27
IE902247L (en) 1990-12-22
RU2104270C1 (ru) 1998-02-10
CA2060897A1 (en) 1990-12-23
NO915049L (no) 1992-02-21
WO1990015799A1 (en) 1990-12-27
FI100800B (fi) 1998-02-27
DE69025998T2 (de) 1996-08-08
EP0409410A1 (en) 1991-01-23
FI915999A0 (fi) 1991-12-19
IE902247A1 (en) 1991-01-16
HRP920903A2 (hr) 1994-04-30
EP0409410B1 (en) 1996-03-20
NO177932C (no) 1995-12-20
NZ234175A (en) 1992-12-23
PT94468B (pt) 1997-12-31
DE69025998D1 (de) 1996-04-25

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Legal Events

Date Code Title Description
A1OB Publication of a patent application
AIPI Request for the grant of a patent on the basis of a substantive examination of a patent application
ODRP Renewal fee for the maintenance of a patent

Payment date: 19980622

Year of fee payment: 9

B1PR Patent granted
PBON Lapse due to non-payment of renewal fee

Effective date: 19990623