HRP20241231T1 - Tetrahidropiridopirazin modulatori gpr6 - Google Patents
Tetrahidropiridopirazin modulatori gpr6 Download PDFInfo
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- HRP20241231T1 HRP20241231T1 HRP20241231TT HRP20241231T HRP20241231T1 HR P20241231 T1 HRP20241231 T1 HR P20241231T1 HR P20241231T T HRP20241231T T HR P20241231TT HR P20241231 T HRP20241231 T HR P20241231T HR P20241231 T1 HRP20241231 T1 HR P20241231T1
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- pharmaceutically acceptable
- compound
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Classifications
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
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- A—HUMAN NECESSITIES
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
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- Addiction (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762520430P | 2017-06-15 | 2017-06-15 | |
| US201762591247P | 2017-11-28 | 2017-11-28 | |
| US201862649856P | 2018-03-29 | 2018-03-29 | |
| US201862672261P | 2018-05-16 | 2018-05-16 | |
| PCT/US2018/037687 WO2018232202A1 (en) | 2017-06-15 | 2018-06-15 | Tetrahydropyridopyrazine modulators of gpr6 |
| EP18818829.6A EP3638673B9 (en) | 2017-06-15 | 2018-06-15 | Tetrahydropyridopyrazine modulators of gpr6 |
Publications (1)
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| HRP20241231T1 true HRP20241231T1 (hr) | 2024-12-20 |
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|---|---|---|---|
| HRP20241231TT HRP20241231T1 (hr) | 2017-06-15 | 2018-06-15 | Tetrahidropiridopirazin modulatori gpr6 |
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| US (1) | US10406157B2 (https=) |
| EP (1) | EP3638673B9 (https=) |
| JP (2) | JP7460369B2 (https=) |
| KR (1) | KR102802861B1 (https=) |
| CN (1) | CN110730781B (https=) |
| AU (1) | AU2018285677B2 (https=) |
| CA (1) | CA3067032A1 (https=) |
| CO (1) | CO2019015086A2 (https=) |
| DK (1) | DK3638673T3 (https=) |
| ES (1) | ES2988680T3 (https=) |
| FI (1) | FI3638673T3 (https=) |
| HR (1) | HRP20241231T1 (https=) |
| HU (1) | HUE068346T2 (https=) |
| IL (1) | IL271332B2 (https=) |
| JO (1) | JOP20180057A1 (https=) |
| LT (1) | LT3638673T (https=) |
| MX (1) | MX2019014940A (https=) |
| PH (1) | PH12019502792A1 (https=) |
| PL (1) | PL3638673T3 (https=) |
| PT (1) | PT3638673T (https=) |
| RS (1) | RS66018B1 (https=) |
| SG (1) | SG11201912149WA (https=) |
| SI (1) | SI3638673T1 (https=) |
| TW (1) | TWI775874B (https=) |
| WO (1) | WO2018232202A1 (https=) |
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| WO2026067262A1 (zh) * | 2024-09-26 | 2026-04-02 | 四川科伦药物研究院有限公司 | 并环化合物、包含其的药物组合物及其用途和方法 |
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| KR0166088B1 (ko) | 1990-01-23 | 1999-01-15 | . | 수용해도가 증가된 시클로덱스트린 유도체 및 이의 용도 |
| US5376645A (en) | 1990-01-23 | 1994-12-27 | University Of Kansas | Derivatives of cyclodextrins exhibiting enhanced aqueous solubility and the use thereof |
| GB9518953D0 (en) | 1995-09-15 | 1995-11-15 | Pfizer Ltd | Pharmaceutical formulations |
| GB9711643D0 (en) | 1997-06-05 | 1997-07-30 | Janssen Pharmaceutica Nv | Glass thermoplastic systems |
| US7229557B2 (en) | 2004-02-04 | 2007-06-12 | Konec, Inc. | Method to separate stereoisomers |
| US20120101106A1 (en) | 2009-07-09 | 2012-04-26 | Mercer Swati P | Tetrahydronapthyridine Orexin Receptor Antagonists |
| JO3466B1 (ar) * | 2013-12-20 | 2020-07-05 | Takeda Pharmaceuticals Co | مواد ضابطة لتترا هيدرو بيريدوبيرازينات من gpr6 |
| JP6526034B2 (ja) | 2014-02-14 | 2019-06-05 | 武田薬品工業株式会社 | Ｇｐｒ６のピリドピラジンモジュレーター |
| KR20160122215A (ko) * | 2014-02-14 | 2016-10-21 | 다케다 야쿠힌 고교 가부시키가이샤 | Gpr6의 피라진 조절제 |
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2017
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2018
- 2018-06-15 MX MX2019014940A patent/MX2019014940A/es unknown
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