HRP20230534T1 - Ham15-52 analozi s poboljšanom potencijom amilin receptora (hamy3r) - Google Patents

Ham15-52 analozi s poboljšanom potencijom amilin receptora (hamy3r) Download PDF

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Publication number
HRP20230534T1
HRP20230534T1 HRP20230534TT HRP20230534T HRP20230534T1 HR P20230534 T1 HRP20230534 T1 HR P20230534T1 HR P20230534T T HRP20230534T T HR P20230534TT HR P20230534 T HRP20230534 T HR P20230534T HR P20230534 T1 HRP20230534 T1 HR P20230534T1
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HR
Croatia
Prior art keywords
ham15
identity
analog
derivative
seq
Prior art date
Application number
HRP20230534TT
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English (en)
Croatian (hr)
Inventor
Jens Christian Frøslev NIELSEN
Kristoffer Tobias Gustav RIGBOLT
Esben Matzen BECH
Morten LUNDH
Paola MAGOTTI
Borja BALLARÍN-GONZÁLES
Søren Ljungberg PEDERSEN
Niels Vrang
Original Assignee
Gubra Aps
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Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=72659001&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HRP20230534(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Gubra Aps filed Critical Gubra Aps
Publication of HRP20230534T1 publication Critical patent/HRP20230534T1/hr

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Obesity (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
HRP20230534TT 2020-09-24 2021-09-23 Ham15-52 analozi s poboljšanom potencijom amilin receptora (hamy3r) HRP20230534T1 (hr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP20198117 2020-09-24
EP21782735.1A EP4021929B1 (en) 2020-09-24 2021-09-23 Ham15-52 analogues with improved amylin receptor (hamy3r) potency
PCT/EP2021/076250 WO2022063925A1 (en) 2020-09-24 2021-09-23 Ham15-52 analogues with improved amylin receptor (hamy3r) potency

Publications (1)

Publication Number Publication Date
HRP20230534T1 true HRP20230534T1 (hr) 2023-08-04

Family

ID=72659001

Family Applications (1)

Application Number Title Priority Date Filing Date
HRP20230534TT HRP20230534T1 (hr) 2020-09-24 2021-09-23 Ham15-52 analozi s poboljšanom potencijom amilin receptora (hamy3r)

Country Status (21)

Country Link
US (2) US12139520B2 (https=)
EP (1) EP4021929B1 (https=)
JP (1) JP2023544959A (https=)
KR (1) KR20230073176A (https=)
CN (1) CN116322741A (https=)
AU (1) AU2021350396A1 (https=)
BR (1) BR112023002525A2 (https=)
CA (1) CA3189267A1 (https=)
DK (1) DK4021929T5 (https=)
ES (1) ES2950137T3 (https=)
FI (1) FI4021929T3 (https=)
HR (1) HRP20230534T1 (https=)
HU (1) HUE062560T2 (https=)
IL (1) IL300620B2 (https=)
MX (1) MX2023002182A (https=)
PL (1) PL4021929T3 (https=)
PT (1) PT4021929T (https=)
RS (1) RS64256B1 (https=)
SI (1) SI4021929T1 (https=)
WO (1) WO2022063925A1 (https=)
ZA (1) ZA202301635B (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI815327B (zh) 2021-03-03 2023-09-11 美商美國禮來大藥廠 長效澱粉素受體促效劑及其用途
IL317600B2 (en) 2022-07-01 2026-03-01 Gubra As Amylin receptor (HAMY3R) agonists with improved chemical stability
TW202540155A (zh) 2023-11-30 2025-10-16 丹麥商諾佛 儂迪克股份有限公司 Glp-1、gip及澱粉素受體之三重促效劑

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5288931A (en) * 1991-12-06 1994-02-22 Genentech, Inc. Method for refolding insoluble, misfolded insulin-like growth factor-I into an active conformation
GB9912350D0 (en) * 1999-05-26 1999-07-28 European Molecular Biology Lab Embl Modified cytokine
FI117667B (fi) * 2001-07-05 2007-01-15 Univ Zuerich Farmaseuttinen koostumus, joka soveltuu käytettäväksi ortopediassa ja hammaslääketieteessä
NZ579621A (en) * 2004-02-11 2011-03-31 Amylin Pharmaceuticals Inc Hybrid polypeptides with selectable properties
WO2007022123A2 (en) 2005-08-11 2007-02-22 Amylin Pharmaceuticals, Inc. Hybrid polypeptides with selectable properties
AU2012212047A1 (en) * 2011-02-03 2013-08-22 Xoma Technology Ltd. Methods and materials for enhancing functional protein expression in bacteria
JP6121992B2 (ja) 2011-06-10 2017-04-26 ノヴォ ノルディスク アー/エス ポリペプチド
AR097701A1 (es) * 2013-09-19 2016-04-13 Zealand Pharma As Análogos de amilina
BR112017019378A2 (pt) 2015-03-18 2019-02-19 Zealand Pharma A/S análogos de amilina
WO2019005623A1 (en) 2017-06-30 2019-01-03 Adepthera Llc PEPTIDE ANALOGS
AR116632A1 (es) 2018-10-11 2021-05-26 Intarcia Therapeutics Inc Polipéptidos análogos de la amilina humana y sus métodos de uso

Also Published As

Publication number Publication date
CA3189267A1 (en) 2022-03-31
AU2021350396A1 (en) 2023-03-16
CN116322741A (zh) 2023-06-23
IL300620B2 (en) 2025-12-01
IL300620A (en) 2023-04-01
JP2023544959A (ja) 2023-10-26
ZA202301635B (en) 2024-03-27
BR112023002525A2 (pt) 2023-04-04
WO2022063925A1 (en) 2022-03-31
KR20230073176A (ko) 2023-05-25
HUE062560T2 (hu) 2023-11-28
RS64256B1 (sr) 2023-07-31
IL300620B1 (en) 2025-08-01
US20240101634A1 (en) 2024-03-28
PL4021929T3 (pl) 2023-07-31
FI4021929T3 (fi) 2023-06-14
PT4021929T (pt) 2023-06-21
SI4021929T1 (sl) 2023-09-29
ES2950137T3 (es) 2023-10-05
DK4021929T5 (da) 2024-07-29
MX2023002182A (es) 2023-11-16
DK4021929T3 (da) 2023-07-10
US12139520B2 (en) 2024-11-12
EP4021929B1 (en) 2023-04-26
US20250129134A1 (en) 2025-04-24
EP4021929A1 (en) 2022-07-06

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