DK4021929T5 - hAM15-52-analoger med forbedret amylinreceptor (hAMY3R)-potens - Google Patents

hAM15-52-analoger med forbedret amylinreceptor (hAMY3R)-potens Download PDF

Info

Publication number
DK4021929T5
DK4021929T5 DK21782735.1T DK21782735T DK4021929T5 DK 4021929 T5 DK4021929 T5 DK 4021929T5 DK 21782735 T DK21782735 T DK 21782735T DK 4021929 T5 DK4021929 T5 DK 4021929T5
Authority
DK
Denmark
Prior art keywords
hamy3r
ham15
potency
analogs
amylin receptor
Prior art date
Application number
DK21782735.1T
Other languages
Danish (da)
English (en)
Other versions
DK4021929T3 (da
Inventor
Jens Christian Frøslev Nielsen
Kristoffer Tobias Gustav Rigbolt
Esben Matzen Bech
Morten Lundh
Paola Magotti
Borja Ballarín-Gonzáles
Søren Ljungberg Pedersen
Niels Vrang
Original Assignee
Gubra As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=72659001&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK4021929(T5) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Gubra As filed Critical Gubra As
Application granted granted Critical
Publication of DK4021929T3 publication Critical patent/DK4021929T3/da
Publication of DK4021929T5 publication Critical patent/DK4021929T5/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Obesity (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK21782735.1T 2020-09-24 2021-09-23 hAM15-52-analoger med forbedret amylinreceptor (hAMY3R)-potens DK4021929T5 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP20198117 2020-09-24
PCT/EP2021/076250 WO2022063925A1 (en) 2020-09-24 2021-09-23 Ham15-52 analogues with improved amylin receptor (hamy3r) potency

Publications (2)

Publication Number Publication Date
DK4021929T3 DK4021929T3 (da) 2023-07-10
DK4021929T5 true DK4021929T5 (da) 2024-07-29

Family

ID=72659001

Family Applications (1)

Application Number Title Priority Date Filing Date
DK21782735.1T DK4021929T5 (da) 2020-09-24 2021-09-23 hAM15-52-analoger med forbedret amylinreceptor (hAMY3R)-potens

Country Status (21)

Country Link
US (2) US12139520B2 (https=)
EP (1) EP4021929B1 (https=)
JP (1) JP2023544959A (https=)
KR (1) KR20230073176A (https=)
CN (1) CN116322741A (https=)
AU (1) AU2021350396A1 (https=)
BR (1) BR112023002525A2 (https=)
CA (1) CA3189267A1 (https=)
DK (1) DK4021929T5 (https=)
ES (1) ES2950137T3 (https=)
FI (1) FI4021929T3 (https=)
HR (1) HRP20230534T1 (https=)
HU (1) HUE062560T2 (https=)
IL (1) IL300620B2 (https=)
MX (1) MX2023002182A (https=)
PL (1) PL4021929T3 (https=)
PT (1) PT4021929T (https=)
RS (1) RS64256B1 (https=)
SI (1) SI4021929T1 (https=)
WO (1) WO2022063925A1 (https=)
ZA (1) ZA202301635B (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI815327B (zh) 2021-03-03 2023-09-11 美商美國禮來大藥廠 長效澱粉素受體促效劑及其用途
IL317600B2 (en) 2022-07-01 2026-03-01 Gubra As Amylin receptor (HAMY3R) agonists with improved chemical stability
TW202540155A (zh) 2023-11-30 2025-10-16 丹麥商諾佛 儂迪克股份有限公司 Glp-1、gip及澱粉素受體之三重促效劑

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5288931A (en) * 1991-12-06 1994-02-22 Genentech, Inc. Method for refolding insoluble, misfolded insulin-like growth factor-I into an active conformation
GB9912350D0 (en) * 1999-05-26 1999-07-28 European Molecular Biology Lab Embl Modified cytokine
FI117667B (fi) * 2001-07-05 2007-01-15 Univ Zuerich Farmaseuttinen koostumus, joka soveltuu käytettäväksi ortopediassa ja hammaslääketieteessä
NZ579621A (en) * 2004-02-11 2011-03-31 Amylin Pharmaceuticals Inc Hybrid polypeptides with selectable properties
WO2007022123A2 (en) 2005-08-11 2007-02-22 Amylin Pharmaceuticals, Inc. Hybrid polypeptides with selectable properties
AU2012212047A1 (en) * 2011-02-03 2013-08-22 Xoma Technology Ltd. Methods and materials for enhancing functional protein expression in bacteria
JP6121992B2 (ja) 2011-06-10 2017-04-26 ノヴォ ノルディスク アー/エス ポリペプチド
AR097701A1 (es) * 2013-09-19 2016-04-13 Zealand Pharma As Análogos de amilina
BR112017019378A2 (pt) 2015-03-18 2019-02-19 Zealand Pharma A/S análogos de amilina
WO2019005623A1 (en) 2017-06-30 2019-01-03 Adepthera Llc PEPTIDE ANALOGS
AR116632A1 (es) 2018-10-11 2021-05-26 Intarcia Therapeutics Inc Polipéptidos análogos de la amilina humana y sus métodos de uso

Also Published As

Publication number Publication date
CA3189267A1 (en) 2022-03-31
AU2021350396A1 (en) 2023-03-16
CN116322741A (zh) 2023-06-23
IL300620B2 (en) 2025-12-01
IL300620A (en) 2023-04-01
JP2023544959A (ja) 2023-10-26
ZA202301635B (en) 2024-03-27
HRP20230534T1 (hr) 2023-08-04
BR112023002525A2 (pt) 2023-04-04
WO2022063925A1 (en) 2022-03-31
KR20230073176A (ko) 2023-05-25
HUE062560T2 (hu) 2023-11-28
RS64256B1 (sr) 2023-07-31
IL300620B1 (en) 2025-08-01
US20240101634A1 (en) 2024-03-28
PL4021929T3 (pl) 2023-07-31
FI4021929T3 (fi) 2023-06-14
PT4021929T (pt) 2023-06-21
SI4021929T1 (sl) 2023-09-29
ES2950137T3 (es) 2023-10-05
MX2023002182A (es) 2023-11-16
DK4021929T3 (da) 2023-07-10
US12139520B2 (en) 2024-11-12
EP4021929B1 (en) 2023-04-26
US20250129134A1 (en) 2025-04-24
EP4021929A1 (en) 2022-07-06

Similar Documents

Publication Publication Date Title
DK4021929T5 (da) hAM15-52-analoger med forbedret amylinreceptor (hAMY3R)-potens
EP3870593A4 (en) NUCLEOTIDE ANALOGUES
EP4069686C0 (en) GLP-1 RECEPTOR AGONIST
DK4122954T3 (da) Novel GLP-1-analoger
EP4199925A4 (en) CYCLOPENTAPYRROLE OREXIN RECEPTOR AGONISTS
MA54545A (fr) Analogues de rifamycine et conjugués anticorps-médicament de ceux-ci
EP3821642C0 (en) IMPROVED NON-CUT INTERCELLULAR TRANSFER FAILURE (MBB)
EP4214120C0 (en) AIRCRAFT STRUCTURE
SI3820874T1 (sl) Selektivni razgrajevalci estrogenskih receptorjev
EP4244344A4 (en) MULTIPLEX EPIGENOME EDITION
PL3956328T3 (pl) Stałe postaci modulatora receptora toll-podobnego
EP3793493C0 (en) PORTABLE ASSISTANCE DEVICE
IL283673A (en) Deuterated analogs of acetyl-leucine
LT3914600T (lt) Tiazolopiridino dariniai kaip adenozino receptoriaus antagonistai
EP4081450C0 (en) HULL STRUCTURE
PL4200093T3 (pl) Podajnik
EP3784265A4 (en) MODULATORS OF THE THIOETHER CYCLIC PEPTIDE AMYLIN RECEPTOR
ES1277256Y (es) Estacion de preparacion de pedidos
EP4006033A4 (en) ADENOSIN RECEPTOR ANTAGONIST
EP4452969A4 (en) INDAZOLE PIPERAZINE-BASED GLUCOCORTICOID RECEPTOR ANTAGONISTS
EP3866932A4 (en) 6-mercaptopurine nucleoside analogues
DK3729079T3 (da) Potensassay af sekretomer
EP3906225C0 (en) Pantothenamide analogues
EP4101115A4 (en) BIDIRECTIONAL BUFFER WITH CIRCUIT PROTECTION TIME SYNCHRONIZATION
EP4006032A4 (en) Adenosine receptor antagonist