HRP20220401T3 - Nova vizualizacijska sredstva za detektiranje neurološke disfunkcije - Google Patents
Nova vizualizacijska sredstva za detektiranje neurološke disfunkcijeInfo
- Publication number
- HRP20220401T3 HRP20220401T3 HRP20220401TT HRP20220401T HRP20220401T3 HR P20220401 T3 HRP20220401 T3 HR P20220401T3 HR P20220401T T HRP20220401T T HR P20220401TT HR P20220401 T HRP20220401 T HR P20220401T HR P20220401 T3 HRP20220401 T3 HR P20220401T3
- Authority
- HR
- Croatia
- Prior art keywords
- imaging agents
- neurological dysfunction
- novel imaging
- detecting neurological
- detecting
- Prior art date
Links
- 239000012216 imaging agent Substances 0.000 title 1
- 230000009251 neurologic dysfunction Effects 0.000 title 1
- 208000015015 neurological dysfunction Diseases 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
- C07B59/002—Heterocyclic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Hematology (AREA)
- Anesthesiology (AREA)
- Child & Adolescent Psychology (AREA)
- Diabetes (AREA)
- Hospice & Palliative Care (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pyrane Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Indole Compounds (AREA)
- Quinoline Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US6610108P | 2008-02-14 | 2008-02-14 | |
| EP09711194.2A EP2247558B2 (en) | 2008-02-14 | 2009-02-17 | Novel imaging agents for detecting neurological dysfunction |
| PCT/US2009/000961 WO2009102498A1 (en) | 2008-02-14 | 2009-02-17 | Novel imaging agents for detecting neurological dysfunction |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HRP20220401T3 true HRP20220401T3 (hr) | 2022-05-27 |
| HRP20220401T4 HRP20220401T4 (hr) | 2024-09-27 |
Family
ID=40627498
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HRP20220401TT HRP20220401T4 (hr) | 2008-02-14 | 2009-02-17 | Nova vizualizacijska sredstva za detektiranje neurološke disfunkcije |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US20110046378A1 (hr) |
| EP (2) | EP2599763A1 (hr) |
| JP (1) | JP2011512354A (hr) |
| KR (1) | KR20100135235A (hr) |
| CA (1) | CA2715390A1 (hr) |
| CY (1) | CY1125258T1 (hr) |
| DK (1) | DK2247558T4 (hr) |
| ES (1) | ES2907992T5 (hr) |
| FI (1) | FI2247558T4 (hr) |
| HR (1) | HRP20220401T4 (hr) |
| HU (1) | HUE058352T2 (hr) |
| LT (1) | LT2247558T (hr) |
| PL (1) | PL2247558T5 (hr) |
| PT (1) | PT2247558T (hr) |
| SI (1) | SI2247558T2 (hr) |
| WO (1) | WO2009102498A1 (hr) |
Families Citing this family (52)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8932557B2 (en) | 2008-02-14 | 2015-01-13 | Eli Lilly And Company | Imaging agents for detecting neurological dysfunction |
| FI2247558T4 (fi) | 2008-02-14 | 2024-09-19 | Lilly Co Eli | Uusia kuvantamisaineita neurologisen toimintahäiriön toteamiseen |
| AU2009279172A1 (en) * | 2008-08-08 | 2010-02-11 | Neurosearch A/S | Novel diphenyl 1,2,3-triazole derivatives useful as modulators of nicotinic acetylcholine receptors |
| US9839699B2 (en) * | 2008-09-18 | 2017-12-12 | Yeda Research And Development Co., Ltd. | Optical method for detecting Alzheimer's disease by systemic administration of curcumin |
| US8691187B2 (en) * | 2009-03-23 | 2014-04-08 | Eli Lilly And Company | Imaging agents for detecting neurological disorders |
| GB201016038D0 (en) | 2010-09-24 | 2010-11-10 | Ge Healthcare Ltd | In vivo imaging method |
| JP5928901B2 (ja) * | 2010-10-29 | 2016-06-01 | クリノ株式会社 | タウイメージングプローブ |
| WO2013020184A1 (en) * | 2011-08-11 | 2013-02-14 | Neuprotect Pty Ltd | Flavonoid compounds, and methods of use thereof |
| US20130315825A1 (en) * | 2012-05-03 | 2013-11-28 | Washington University | Tricyclic heteroaromatic compounds as alpha-synuclein ligands |
| CN104781234A (zh) * | 2012-05-22 | 2015-07-15 | 伊莱利利公司 | 用于检测神经功能障碍的基于咔啉和咔唑的成像剂 |
| SG11201504901PA (en) | 2012-12-21 | 2015-07-30 | Nat Inst Radiolog | Novel compound for imaging tau protein accumulated in the brain |
| WO2014194169A1 (en) | 2013-05-31 | 2014-12-04 | The General Hospital Corporation | Radiosynthesis of tau radiopharmaceuticals |
| UY35625A (es) | 2013-06-25 | 2014-12-31 | Bristol Myers Squibb Company Una Corporación Del Estado De Delaware | Compuestos de tetrahidrocarbazol y carbazol carboxamida sustituidos como inhibidores de quinasa |
| WO2014210087A1 (en) | 2013-06-25 | 2014-12-31 | Bristol-Myers Squibb Company | Carbazole carboxamide compounds useful as kinase inhibitors |
| TWI513698B (zh) * | 2013-10-08 | 2015-12-21 | Hoffmann La Roche | 做為tau-pet-配位體之二氮雜咔唑衍生物 |
| TWI667233B (zh) | 2013-12-19 | 2019-08-01 | 德商拜耳製藥公司 | 新穎吲唑羧醯胺,其製備方法、含彼等之醫藥製劑及其製造醫藥之用途 |
| US10662193B2 (en) | 2014-01-21 | 2020-05-26 | Ac Immune Sa | Carbazole and carboline compounds for use in the diagnosis, treatment, alleviation or prevention of disorders associated with amyloid or amyloid-like proteins |
| KR102530129B1 (ko) | 2014-05-13 | 2023-05-10 | 에프. 호프만-라 로슈 아게 | 중수소화된 헤테로사이클릭 화합물 및 이의 조영제로서의 용도 |
| KR20170052626A (ko) | 2014-09-05 | 2017-05-12 | 심바이오믹스 세러퓨틱스 엘엘씨 | 세균질증 치료에 사용하기 위한 세크니다졸 |
| JP6782227B2 (ja) * | 2014-09-05 | 2020-11-11 | ザ・ジョンズ・ホプキンス・ユニバーシティー | CaMKII阻害剤及びその使用 |
| LT3461821T (lt) | 2014-10-24 | 2020-08-10 | Bristol-Myers Squibb Company | Indolo karboksamido junginiai, naudotini kaip kinazės inhibitoriai |
| LT3209651T (lt) | 2014-10-24 | 2020-01-10 | Bristol-Myers Squibb Company | Karbazolo dariniai |
| JP6592512B2 (ja) | 2014-10-24 | 2019-10-16 | ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company | 三環式アトロプ異性体の化合物 |
| CN107207508B (zh) | 2015-02-02 | 2020-02-28 | Ucb生物制药私人有限公司 | 9h-吡咯并-二吡啶衍生物 |
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| CN105524034B (zh) * | 2015-03-27 | 2018-08-17 | 北京大学 | 香豆素衍生物的制备、药理作用及治疗脑缺血的应用 |
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| EP3322707A1 (en) | 2015-07-15 | 2018-05-23 | AC Immune SA | Novel imaging compounds |
| EP3118202A1 (en) | 2015-07-15 | 2017-01-18 | AC Immune S.A. | Dihydropyridopyrrole derivatives as tau-pet-ligands |
| AU2016351609B2 (en) | 2015-11-13 | 2019-08-08 | Eli Lilly And Company | Azetidine derivatives for tau imaging |
| CA3010690A1 (en) * | 2016-02-03 | 2017-08-10 | Janssen Pharmaceutica Nv | Tau pet imaging ligands |
| US10865207B2 (en) | 2016-07-22 | 2020-12-15 | Ac Immune S.A. | Compounds for imaging Tau protein aggregates |
| MX386900B (es) * | 2016-07-22 | 2025-03-19 | Ac Immune S A Star | Compuestos para formacion de imagenes de agregados de proteinas tau. |
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| WO2018024643A1 (en) | 2016-08-02 | 2018-02-08 | Ucb Biopharma Sprl | 9h-pyrrolo-dipyridine derivatives |
| MX375720B (es) | 2016-09-09 | 2025-03-04 | Hoffmann La Roche | Proceso para preparacion de 2-(6-nitropiridin-3-il)-9h-dipirido[2,3-beta;3',4'-d]pirrol. |
| TW201906818A (zh) | 2017-05-31 | 2019-02-16 | 美商511製藥公司 | 新穎氘取代之正子發射斷層掃描(pet)顯影劑及其藥理應用 |
| EP3743426A1 (en) | 2018-01-24 | 2020-12-02 | AC Immune SA | Azacarboline compounds for the detection of tau aggregates |
| US11306089B2 (en) | 2018-01-24 | 2022-04-19 | Life Molecular Imaging Limited | Gamma-carboline compounds for the detection of Tau aggregates |
| JPWO2019168170A1 (ja) * | 2018-03-02 | 2021-03-04 | 国立大学法人 長崎大学 | クロモン誘導体及びアミロイド関連疾患診断用組成物 |
| CN112384517B (zh) | 2018-05-09 | 2023-07-14 | 新旭生技股份有限公司 | 杂芳基化合物及其用途 |
| WO2021055670A1 (en) | 2019-09-20 | 2021-03-25 | Avx Corporation | Somatic cell-based electrical biosensor |
| CA3161455A1 (en) | 2019-11-13 | 2021-05-20 | Aprinoia Therapeutics Limited | Compounds for degrading tau protein aggregates and uses thereof |
| US12280037B2 (en) | 2020-09-22 | 2025-04-22 | Evofem Biosciences, Inc. | Method and pharmaceutical composition for treating or preventing trichomoniasis and uses thereof |
| US20240368106A1 (en) * | 2021-08-30 | 2024-11-07 | Pretzel Therapeutics, Inc. | Hydroxy and alkoxy coumarins as modulators of polrmt |
| WO2023034346A1 (en) * | 2021-08-30 | 2023-03-09 | Pretzel Therapeutics, Inc. | Chromen-2-one modulators of polrmt |
| US11938127B2 (en) | 2021-09-28 | 2024-03-26 | Wayne State University | Methods and compositions relating to steroid hormone receptor-dependent proliferative disorders |
| CA3237199A1 (en) | 2021-11-02 | 2023-05-11 | Flare Therapeutics Inc. | Pparg inverse agonists and uses thereof |
| WO2023204967A1 (en) * | 2022-04-21 | 2023-10-26 | Virginia Commonwealth University | Nlrp3 inflammasome inhibitors and compositions and uses thereof |
| TW202404969A (zh) | 2022-04-22 | 2024-02-01 | 美商維泰克斯製藥公司 | 用於治療疼痛之雜芳基化合物 |
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| WO2025155625A1 (en) | 2024-01-16 | 2025-07-24 | Eli Lilly And Company | Novel compounds for tau imaging |
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| CN107207508B (zh) | 2015-02-02 | 2020-02-28 | Ucb生物制药私人有限公司 | 9h-吡咯并-二吡啶衍生物 |
-
2009
- 2009-02-17 FI FIEP09711194.2T patent/FI2247558T4/fi active
- 2009-02-17 KR KR1020107020589A patent/KR20100135235A/ko not_active Ceased
- 2009-02-17 EP EP20130157487 patent/EP2599763A1/en not_active Withdrawn
- 2009-02-17 PT PT97111942T patent/PT2247558T/pt unknown
- 2009-02-17 US US12/867,502 patent/US20110046378A1/en not_active Abandoned
- 2009-02-17 US US12/372,717 patent/US8318132B2/en active Active
- 2009-02-17 ES ES09711194T patent/ES2907992T5/es active Active
- 2009-02-17 WO PCT/US2009/000961 patent/WO2009102498A1/en not_active Ceased
- 2009-02-17 HU HUE09711194A patent/HUE058352T2/hu unknown
- 2009-02-17 HR HRP20220401TT patent/HRP20220401T4/hr unknown
- 2009-02-17 DK DK09711194.2T patent/DK2247558T4/da active
- 2009-02-17 SI SI200932157T patent/SI2247558T2/sl unknown
- 2009-02-17 CA CA2715390A patent/CA2715390A1/en not_active Abandoned
- 2009-02-17 LT LTEPPCT/US2009/000961T patent/LT2247558T/lt unknown
- 2009-02-17 PL PL09711194.2T patent/PL2247558T5/pl unknown
- 2009-02-17 EP EP09711194.2A patent/EP2247558B2/en active Active
- 2009-02-17 JP JP2010546795A patent/JP2011512354A/ja active Pending
-
2022
- 2022-03-30 CY CY20221100245T patent/CY1125258T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US8318132B2 (en) | 2012-11-27 |
| DK2247558T3 (da) | 2022-02-21 |
| LT2247558T (lt) | 2022-04-11 |
| PL2247558T5 (pl) | 2024-10-14 |
| CA2715390A1 (en) | 2009-08-20 |
| PT2247558T (pt) | 2022-03-21 |
| EP2247558B1 (en) | 2022-02-02 |
| ES2907992T3 (es) | 2022-04-27 |
| ES2907992T5 (en) | 2025-03-19 |
| WO2009102498A1 (en) | 2009-08-20 |
| EP2599763A1 (en) | 2013-06-05 |
| SI2247558T1 (sl) | 2022-07-29 |
| SI2247558T2 (sl) | 2024-10-30 |
| EP2247558A1 (en) | 2010-11-10 |
| KR20100135235A (ko) | 2010-12-24 |
| US20110046378A1 (en) | 2011-02-24 |
| PL2247558T3 (pl) | 2022-05-02 |
| JP2011512354A (ja) | 2011-04-21 |
| HRP20220401T4 (hr) | 2024-09-27 |
| DK2247558T4 (da) | 2024-07-29 |
| EP2247558B2 (en) | 2024-07-03 |
| FI2247558T4 (fi) | 2024-09-19 |
| HUE058352T2 (hu) | 2022-07-28 |
| US20110091382A1 (en) | 2011-04-21 |
| CY1125258T1 (el) | 2024-02-16 |
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