HRP20200950T1 - Polu-sintetički materijal od praha, dobiven izmjenjivanjem sastava prirodnog morskog biomaterijala, metoda za proizvodnju istog i njihove primjene - Google Patents

Polu-sintetički materijal od praha, dobiven izmjenjivanjem sastava prirodnog morskog biomaterijala, metoda za proizvodnju istog i njihove primjene Download PDF

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HRP20200950T1
HRP20200950T1 HRP20200950TT HRP20200950T HRP20200950T1 HR P20200950 T1 HRP20200950 T1 HR P20200950T1 HR P20200950T T HRP20200950T T HR P20200950TT HR P20200950 T HRP20200950 T HR P20200950T HR P20200950 T1 HRP20200950 T1 HR P20200950T1
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semi
hippopus
material according
synthetic material
aragonite
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HRP20200950TT
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Georges Camprasse
Serge Camprasse
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Mbp (Mauritius) Ltd
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    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/0005—Ingredients of undetermined constitution or reaction products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/618—Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
    • A—HUMAN NECESSITIES
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    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001—Use of materials characterised by their function or physical properties
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001—Use of materials characterised by their function or physical properties
    • A61L24/0042—Materials resorbable by the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/0047—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L24/0052—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material with an inorganic matrix
    • A—HUMAN NECESSITIES
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    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/0047—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L24/0052—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material with an inorganic matrix
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    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
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    • A61L24/0073—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material with a macromolecular matrix
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    • A61L24/02—Surgical adhesives or cements; Adhesives for colostomy devices containing inorganic materials
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    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
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    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
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    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
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    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/42—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having an inorganic matrix
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/42—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having an inorganic matrix
    • A61L27/427—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having an inorganic matrix of other specific inorganic materials not covered by A61L27/422 or A61L27/425
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    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
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    • A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A61L27/446—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with other specific inorganic fillers other than those covered by A61L27/443 or A61L27/46
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    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
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    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01F—COMPOUNDS OF THE METALS BERYLLIUM, MAGNESIUM, ALUMINIUM, CALCIUM, STRONTIUM, BARIUM, RADIUM, THORIUM, OR OF THE RARE-EARTH METALS
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    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants

Claims (17)

1. Praškasti polusintetički materijal, dobiven iz prirodnog morskog biomaterijala, s dodatkom netopljivih i topljivih biopolimera i kalcijevog karbonata transformiranog karbonacijom, navedeni polusintetički materijal je bioapsorbiran i prirodni morski biomaterijal je aragonit unutarnji sloj školjke školjkaša.
2. Polusintetički materijal prema zahtjevu 1, naznačen time što su školjkaši izabrani iz skupine koja sadrži pinktade, osobito Pinctada maxima, margaritifera i tridakne, osobito Tridacna gigas, maxima, derasa, tevaroa, squamosa, crocea, Hipopus hippopus, Hipopus porcelanus, navedeni aragonit sloj je u praškastom obliku.
3. Polusintetički materijal prema zahtjevu 1 ili 2, naznačen time što prirodni biomaterijal u praškastom obliku ima granulometriju od 5 nm do 100 μm, poželjno od 20 nm do 50 μm, još poželjnije od 50 nm do 20 μm.
4. Polusintetički materijal prema bilo kojem od zahtjeva 1 do 3, naznačen time što se netopljivi i topljivi biopolimeri izvade iz aragonita unutarnjeg sloja i / ili iz kalcitnog vanjskog sloja školjke školjkaša izabranih iz skupine koja sadrži pinktade, posebno Pinctada maxima, margaritifera i tridakne, osobito Tridacna gigas, maksima, derasa, tevaroa, squamosa, crocea, Hippopus hippopus, Hippopus porcelanus.
5. Polusintetički materijal prema bilo kojem od zahtjeva 1 do 4, naznačen time što kalcijev karbonat transformiran karbonizacijom potječe iz prirodnog zemaljskog, prirodnog morskog ili taloženog kalcijevog karbonata, ili iz neorganske frakcije aragonit sloja nakon vađenja netopljivih i topljivih biopolimera.
6. Postupak za pripremu materijala prema bilo kojem od zahtjeva 1 do 5, koji sadrži miješanje mljevenog prirodnog biomaterijala, netopljivih i topljivih polimera izvađenih iz aragonita unutrašnjeg sloja i / ili iz kalcitnog vanjskog sloja školjke školjkaša izabranih između skupina koja sadrži pinktade, osobito Pinctada maxima, margaritifera i tridakne, osobito Tridacna gigas, maxima, derasa, tevaroa, squamosa, crocea, Hippopus hipoma, Hippopus porcelanus, i kalcijev karbonat transformiran karbonacijom.
7. Postupak pripreme prema zahtjevu 6, naznačen time što se mljeveni prirodni biomaterijal dobiva mljevenjem aragonit unutarnjeg sloja školjke školjkaša izabranih iz skupine koja sadrži pinktade, osobito Pinctada maxima, margaritifera i tridakne, osobito Tridacna gigas, maxima, derasa, tevaroa, squamosa, crocea, Hippopus hipoma, Hipopus porcelanus.
8. Postupak za pripremu prema zahtjevu 6 ili 7, naznačen time što obuhvaća korak sferifikacije nakon mljevenja.
9. Postupak prema bilo kojem od zahtjeva 6 do 8, naznačen time što su netopljivi i topljivi biopolimeri izvađeni supercentrifugiranjem i tangencijalnom ultrafiltracijom povezani s reverznom osmozom nakon hidrolize.
10. Postupak prema zahtjevu 9, naznačen time što aragonit unutarnji sloj i / ili kalcitni vanjski sloj školjke mekušaca je (su) umrežen prije vađenja.
11. Postupak prema zahtjevu 9 ili 10, naznačen time što aragonit unutarnji sloj i / ili kalcitni vanjski sloj školjke mekušaca je (su) mljeven i prosijan na granulometriju između 250 μm i 50 μm prije vađenja.
12. Praškasti polusintetički materijal prema bilo kojem od zahtjeva 1 do 5, ili dobiven u skladu s postupkom prema jednom od zahtjeva 6 do 11, za uporabu kao nadomjestak kosti za vanjsku formulaciju, za liječenje i obnavljanje gubitaka tvari, za liječenje opeklina, rana, čireva ili eritematskih lezija na koži.
13. Uporaba praškastog polusintetičkog materijala prema bilo kojem od zahtjeva 1 do 5, ili dobiven u skladu s postupkom prema jednom od zahtjeva 6 do 11 u proizvodnji uređaja ili lijevanih implantata.
14. Uporaba praškastog polusintetičkog materijala prema bilo kojem od zahtjeva 1 do 5, ili dobiven u skladu s postupkom prema jednom od zahtjeva 6 do 11, u proizvodnji uređaja ili lijevanih implantata s kontroliranom bioapsorpcijom, koji sadrže niti šava s bioapsorpcijom raspoređen tokom vremena.
15. Uporaba praškastog polusintetičkog materijala prema bilo kojem od zahtjeva 1 do 5, ili dobivenog u skladu s postupkom prema jednom od zahtjeva 6 do 11, za formulaciju pripravaka za koštane nadomjeske za vanjsku uporabu, za ekstrudirane koštane nadomjeske, posebno pakirane u štrcaljki pod vakumom, koštane nadomjeske s poroznim nosačem kolagena, nadomjeske s mineralnom strukturom životinjskog ili ljudskog porijekla, uređaji za biopsorpcijsku osteosintezu i lijevani implantati, uređaji s kontroliranom bioapsorpcijom, cementi za pečaćenje endoproteza i injekcijski cementi za minimalno invazivnu operaciju u vertebroplastici i kifoplastici.
16. Uporaba kalcijevog karbonata koji je podvrgnut karbonizaciji korišten u materijalu prema bilo kojem od zahtjeva 1 do 5, kao aditiv koji je plastičan, može se modelirati i ljepljiv je, u sastavima koji sadrže kalcijeve soli, prirodne ili sintetičke polimere, kolagen i mineralne strukture koštanih tkiva životinjskog ili ljudskog porijekla.
17. Uporaba netopljivih i topljivih izvađenih biopolimera korištenih u materijalu prema bilo kojem od zahtjeva 1 do 5, kao aditiva u praškastim sastavima koji sadrže kalcijeve soli, prirodne ili sintetičke polimere, kolagen i mineralne strukture koštanih tkiva životinjskog ili ljudskog porijekla.
HRP20200950TT 2015-06-23 2020-06-15 Polu-sintetički materijal od praha, dobiven izmjenjivanjem sastava prirodnog morskog biomaterijala, metoda za proizvodnju istog i njihove primjene HRP20200950T1 (hr)

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Application Number Priority Date Filing Date Title
FR1555782A FR3037801B1 (fr) 2015-06-23 2015-06-23 Materiau semi-synthetique pulverulent, obtenu par modification de la composition d'un biomateriau naturel marin, son procede de fabrication, ses applications
EP16741662.7A EP3313465B1 (fr) 2015-06-23 2016-06-20 Materiau semi-synthetique pulverulent, obtenu par modification de la composition d'un biomateriau naturel marin, son procede de fabrication, ses applications
PCT/FR2016/051497 WO2016207525A1 (fr) 2015-06-23 2016-06-20 Materiau semi-synthetique pulverulent, obtenu par modification de la composition d'un biomateriau naturel marin, son procede de fabrication, ses applications

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Publication number Priority date Publication date Assignee Title
FR3037801B1 (fr) * 2015-06-23 2017-08-11 Jd Invest Materiau semi-synthetique pulverulent, obtenu par modification de la composition d'un biomateriau naturel marin, son procede de fabrication, ses applications
CN109529107B (zh) * 2018-12-07 2021-09-03 中鼎凯瑞科技成都有限公司 多微量元素有机化合物与无机化合物通过水合桥化形成的有机-无机自凝固复合骨移植物
FR3095947B1 (fr) * 2019-05-13 2022-05-13 Mbp Mauritius Ltd Procédé d'isolation des molécules contenues dans les couches organo-minérales des coquilles de mollusques marins bivalves
CN110551826B (zh) * 2019-09-03 2021-07-27 中国科学院南海海洋研究所 鉴定番红砗磲、鳞砗磲及其杂交子一代的微卫星引物、试剂盒和鉴定方法
CN114099761B (zh) * 2020-08-27 2022-06-21 厦门大学 一种浴海绵止血材料及其制备方法和应用
IT202100032900A1 (it) * 2021-12-29 2023-06-29 De Ra Do S R L Metodo e relativo impianto per la riqualificazione di gusci di ostriche e molluschi bivaldi in ottica farmaceutica, culinaria e green

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1450204A (fr) 1965-10-15 1966-05-06 Conditionnement-présentoir pour bouteilles
US3929971A (en) * 1973-03-30 1975-12-30 Research Corp Porous biomaterials and method of making same
NO141366C (no) * 1975-01-21 1980-02-27 Vaw Ver Aluminium Werke Ag Fremgangsmaate til fremstilling av en overveiende magnesiumkarbonatholdig, smaaplateformet kalsium-magnesium-karbonat-blanding med basisk karakter
JPH01117833A (ja) * 1987-10-29 1989-05-10 Masatoshi Kato 生物活性物質
FR2647334A1 (fr) * 1989-05-23 1990-11-30 Cazprasse Serge Produits de remplacement de structures osseuses et radiculo-dentaires en nacre
FR2689400B1 (fr) * 1992-04-03 1995-06-23 Inoteb Materiau pour prothese osseuse contenant des particules de carbonate de calcium dispersees dans une matrice polymere bioresorbable.
FR2706308B1 (fr) * 1993-02-05 1995-09-08 Camprasse Georges Prothèses orthopédiques et ciment de scellement biologique en nacré.
FR2719478B1 (fr) * 1994-05-09 1996-07-26 Serge Camprasse Produit de régénération et de cicatrisation cutanée. Son procédé de fabrication ses applications.
WO1997020784A1 (en) * 1995-12-05 1997-06-12 Periclase Pty. Ltd. A settable composition and uses therefor
FR2743075B1 (fr) * 1995-12-28 1998-03-27 Centre Nat Rech Scient Procede de preparation de substances actives a partir de la nacre, produits obtenus, utiles notamment comme medicaments
JPH1036106A (ja) * 1996-07-26 1998-02-10 Taihei Kagaku Sangyo Kk 多孔質塊状炭酸アパタイトおよびその製造方法
FI105470B (fi) * 1997-09-08 2000-08-31 Fp Pigments Oy Menetelmä ja laitteisto saostetun kalsiumkarbonaatin tuottamiseksi
FR2777190B1 (fr) * 1998-04-14 2001-07-27 Georges Camprasse Procede d'extraction, identification des principes actifs contenus dans la coquille interne et externe des mollusques marins, leur utilisation dans des preparations a visee thera peutique,diagnostic et cosmetique
FR2782641B1 (fr) 1998-08-27 2002-05-10 Regent Genus Organisms Interna Medicament homeopathique comprenant un ou plusieurs composants de la nacre
GB9823307D0 (en) * 1998-10-23 1998-12-23 Regent Genus Organisms Interna Composition for traetment of periodontopathy and related diseases
US6143065A (en) * 1999-07-12 2000-11-07 J. M. Huber Corporation Precipitated calcium carbonate product having improved brightness and method of preparing the same
FR2799125B1 (fr) * 1999-10-05 2002-01-18 Centre Nat Rech Scient Procede de preparation d'une composition par extraction de nacre, comprenant l'integralite des composants de la nacre, composition obtenue par ce procede et son utilisation en pharmacie et cosmetique.
FR2830249B1 (fr) * 2001-10-03 2004-08-13 Toulouse Inst Nat Polytech Composition de ciment hydraulique a base de carbonates de calcium
CN1187092C (zh) * 2001-10-22 2005-02-02 中国科学技术大学 用于药物的具有纳米结构的缓释载体
CN100438930C (zh) * 2006-11-09 2008-12-03 清华大学 骨修复中用珍珠活性物质代替骨生长因子的受控释放方法
CN101209358B (zh) * 2006-12-26 2010-05-19 温州医学院附属第二医院 一种以海洋生物为原料的骨修复材料及其制备工艺
KR100854913B1 (ko) * 2007-10-01 2008-08-28 (주) 세화엠텍 초미립 경질 탄산칼슘 제조방법 및 장치
CN101450226A (zh) * 2007-12-07 2009-06-10 厦门大学 一种以翡翠贻贝粘附蛋白制备生物粘合剂的方法
FR2946888B1 (fr) * 2009-06-17 2011-07-29 Mega Bio Pharma Procede de preparation de nacre mecanostructuree par mecano-synthese, nacre mecanostructuree ainsi obtenue et ses applications
JP5717239B2 (ja) * 2010-08-05 2015-05-13 独立行政法人国立高等専門学校機構 貝殻または真珠由来の水溶性タンパク質の抽出方法
WO2013171736A1 (en) * 2012-05-17 2013-11-21 Cartiheal(2009) Ltd Biomatrix hydrogels and methods of use thereof
FI128031B (en) * 2013-03-13 2019-08-15 Nordkalk Oy Ab A process for preparing nanoparticles in a concentrated slurry
FR3037801B1 (fr) 2015-06-23 2017-08-11 Jd Invest Materiau semi-synthetique pulverulent, obtenu par modification de la composition d'un biomateriau naturel marin, son procede de fabrication, ses applications

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