HRP20170794T1 - Izvedeni peptidi faktora viii za upotrebu u liječenju hemofilije a - Google Patents

Izvedeni peptidi faktora viii za upotrebu u liječenju hemofilije a Download PDF

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Publication number
HRP20170794T1
HRP20170794T1 HRP20170794TT HRP20170794T HRP20170794T1 HR P20170794 T1 HRP20170794 T1 HR P20170794T1 HR P20170794T T HRP20170794T T HR P20170794TT HR P20170794 T HRP20170794 T HR P20170794T HR P20170794 T1 HRP20170794 T1 HR P20170794T1
Authority
HR
Croatia
Prior art keywords
seq
peptide
preparation
subject
factor viii
Prior art date
Application number
HRP20170794TT
Other languages
English (en)
Croatian (hr)
Inventor
David Wraith
Heather Streeter
Original Assignee
Apitope International Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB1220328.7A external-priority patent/GB201220328D0/en
Priority claimed from GBGB1316660.8A external-priority patent/GB201316660D0/en
Application filed by Apitope International Nv filed Critical Apitope International Nv
Publication of HRP20170794T1 publication Critical patent/HRP20170794T1/hr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0008Antigens related to auto-immune diseases; Preparations to induce self-tolerance
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745Blood coagulation or fibrinolysis factors
    • C07K14/755Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/55Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/57Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/577Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 tolerising response
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Rheumatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HRP20170794TT 2012-11-12 2013-11-11 Izvedeni peptidi faktora viii za upotrebu u liječenju hemofilije a HRP20170794T1 (hr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GBGB1220328.7A GB201220328D0 (en) 2012-11-12 2012-11-12 Peptides
GBGB1316660.8A GB201316660D0 (en) 2013-09-19 2013-09-19 Peptides
EP13795002.8A EP2917232B1 (en) 2012-11-12 2013-11-11 Factor viii-derived peptides for use in the treatment of haemophilia a
PCT/IB2013/060060 WO2014072958A1 (en) 2012-11-12 2013-11-11 Peptides

Publications (1)

Publication Number Publication Date
HRP20170794T1 true HRP20170794T1 (hr) 2017-08-11

Family

ID=49627013

Family Applications (1)

Application Number Title Priority Date Filing Date
HRP20170794TT HRP20170794T1 (hr) 2012-11-12 2013-11-11 Izvedeni peptidi faktora viii za upotrebu u liječenju hemofilije a

Country Status (28)

Country Link
US (2) US20150306192A1 (enExample)
EP (1) EP2917232B1 (enExample)
JP (1) JP6247696B2 (enExample)
KR (1) KR102165486B1 (enExample)
CN (1) CN104903347B (enExample)
AU (1) AU2013343024B2 (enExample)
BR (1) BR112015010625B1 (enExample)
CA (1) CA2890835C (enExample)
CY (1) CY1119164T1 (enExample)
DK (1) DK2917232T3 (enExample)
EA (1) EA036483B1 (enExample)
ES (1) ES2626881T3 (enExample)
HR (1) HRP20170794T1 (enExample)
HU (1) HUE033586T2 (enExample)
IL (1) IL238627B (enExample)
IN (1) IN2015DN03814A (enExample)
LT (1) LT2917232T (enExample)
MX (1) MX350777B (enExample)
MY (1) MY176708A (enExample)
NZ (1) NZ708812A (enExample)
PH (1) PH12015501033B1 (enExample)
PL (1) PL2917232T3 (enExample)
PT (1) PT2917232T (enExample)
RS (1) RS56069B1 (enExample)
SG (1) SG11201503657UA (enExample)
SI (1) SI2917232T1 (enExample)
WO (1) WO2014072958A1 (enExample)
ZA (1) ZA201503127B (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018127830A1 (en) 2017-01-04 2018-07-12 Apitope International Nv S-arrestin peptides and therapeutic uses thereof
US11986536B2 (en) 2019-03-23 2024-05-21 Ablevia Biotech Gmbh Compound for the sequestration of undesirable antibodies in a patient
EP3715374A1 (en) 2019-03-23 2020-09-30 Ablevia biotech GmbH Compound for the sequestration of undesirable antibodies in a patient
GB201909774D0 (en) * 2019-07-08 2019-08-21 Apitope Tech Bristol Limited Method
WO2022063887A1 (en) 2020-09-23 2022-03-31 Ablevia Biotech Gmbh Compound for increasing the efficacy of factor viii replacement therapy

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1918298T3 (da) 2000-08-21 2010-11-29 Apitope Technology Bristol Ltd Peptid
WO2002060917A2 (en) * 2000-12-01 2002-08-08 Regents Of The University Of Minnesota Method to treat hemophilia
FR2842812A1 (fr) * 2002-07-26 2004-01-30 Pf Medicament Procede de solubilisation de peptides hydrophobes et leur utilisation pour generer une reponse de type ctl antitumorale ou anti-infectueuse
JP2006188507A (ja) * 2004-12-10 2006-07-20 Tokyo Univ Of Agriculture & Technology 蛋白質の溶解度向上方法
ES2386462T3 (es) * 2005-10-28 2012-08-21 Boehringer Ingelheim International Gmbh Ensayo de la actividad NS2/3 del virus de la hepatitis C
GB0723712D0 (en) * 2007-12-04 2008-01-16 Apitope Technology Bristol Ltd Peptides
GB0801513D0 (en) * 2008-01-28 2008-03-05 Circassia Ltd Peptides from factor VIII
GB0908515D0 (en) * 2009-05-18 2009-06-24 Apitope Technology Bristol Ltd Peptide
CA2780763A1 (en) * 2009-11-13 2011-05-19 Puget Sound Blood Center Factor viii b cell epitope variants having reduced immunogenicity
US8969524B2 (en) * 2010-10-27 2015-03-03 Baxter International Inc. FVIII peptides for immune tolerance induction and immunodiagnostics

Also Published As

Publication number Publication date
BR112015010625A2 (pt) 2017-08-22
HUE033586T2 (hu) 2017-12-28
US20150306192A1 (en) 2015-10-29
PH12015501033A1 (en) 2015-07-27
AU2013343024B2 (en) 2017-06-01
SG11201503657UA (en) 2015-06-29
DK2917232T3 (en) 2017-06-12
CA2890835C (en) 2021-11-23
IN2015DN03814A (enExample) 2015-10-02
NZ708812A (en) 2019-03-29
RS56069B1 (sr) 2017-10-31
KR20150084852A (ko) 2015-07-22
PT2917232T (pt) 2017-06-09
PL2917232T3 (pl) 2017-09-29
AU2013343024A1 (en) 2015-05-21
US20210346476A1 (en) 2021-11-11
SI2917232T1 (sl) 2017-07-31
PH12015501033B1 (en) 2015-07-27
EA201590927A1 (ru) 2015-10-30
EP2917232B1 (en) 2017-03-01
ZA201503127B (en) 2016-10-26
CA2890835A1 (en) 2014-05-15
EA036483B1 (ru) 2020-11-16
CN104903347A (zh) 2015-09-09
LT2917232T (lt) 2017-06-26
EP2917232A1 (en) 2015-09-16
WO2014072958A8 (en) 2016-10-13
MY176708A (en) 2020-08-19
ES2626881T3 (es) 2017-07-26
HK1209138A1 (en) 2016-03-24
WO2014072958A1 (en) 2014-05-15
IL238627B (en) 2018-12-31
BR112015010625B1 (pt) 2023-03-07
JP6247696B2 (ja) 2017-12-13
IL238627A0 (en) 2015-06-30
MX350777B (es) 2017-09-15
CY1119164T1 (el) 2018-02-14
KR102165486B1 (ko) 2020-10-15
CN104903347B (zh) 2020-02-21
MX2015005973A (es) 2015-09-16
JP2016501182A (ja) 2016-01-18

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