JP6247696B2 - ペプチド - Google Patents

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Publication number
JP6247696B2
JP6247696B2 JP2015541291A JP2015541291A JP6247696B2 JP 6247696 B2 JP6247696 B2 JP 6247696B2 JP 2015541291 A JP2015541291 A JP 2015541291A JP 2015541291 A JP2015541291 A JP 2015541291A JP 6247696 B2 JP6247696 B2 JP 6247696B2
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JP
Japan
Prior art keywords
peptide
seq
fviii
glu
lys
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP2015541291A
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English (en)
Japanese (ja)
Other versions
JP2016501182A (ja
Inventor
レイス，デヴィッド
ストリーター，ヘザー
Original Assignee
アピトープ インターナショナル エヌブイ
アピトープ インターナショナル エヌブイ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB1220328.7A external-priority patent/GB201220328D0/en
Priority claimed from GBGB1316660.8A external-priority patent/GB201316660D0/en
Application filed by アピトープ インターナショナル エヌブイ, アピトープ インターナショナル エヌブイ filed Critical アピトープ インターナショナル エヌブイ
Publication of JP2016501182A publication Critical patent/JP2016501182A/ja
Application granted granted Critical
Publication of JP6247696B2 publication Critical patent/JP6247696B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0008—Antigens related to auto-immune diseases; Preparations to induce self-tolerance
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/577—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 tolerising response
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Rheumatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2015541291A 2012-11-12 2013-11-11 ペプチド Expired - Fee Related JP6247696B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB1220328.7 2012-11-12
GBGB1220328.7A GB201220328D0 (en) 2012-11-12 2012-11-12 Peptides
GB1316660.8 2013-09-19
GBGB1316660.8A GB201316660D0 (en) 2013-09-19 2013-09-19 Peptides
PCT/IB2013/060060 WO2014072958A1 (en) 2012-11-12 2013-11-11 Peptides

Publications (2)

Publication Number Publication Date
JP2016501182A JP2016501182A (ja) 2016-01-18
JP6247696B2 true JP6247696B2 (ja) 2017-12-13

Family

ID=49627013

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2015541291A Expired - Fee Related JP6247696B2 (ja) 2012-11-12 2013-11-11 ペプチド

Country Status (28)

Country Link
US (2) US20150306192A1 (enExample)
EP (1) EP2917232B1 (enExample)
JP (1) JP6247696B2 (enExample)
KR (1) KR102165486B1 (enExample)
CN (1) CN104903347B (enExample)
AU (1) AU2013343024B2 (enExample)
BR (1) BR112015010625B1 (enExample)
CA (1) CA2890835C (enExample)
CY (1) CY1119164T1 (enExample)
DK (1) DK2917232T3 (enExample)
EA (1) EA036483B1 (enExample)
ES (1) ES2626881T3 (enExample)
HR (1) HRP20170794T1 (enExample)
HU (1) HUE033586T2 (enExample)
IL (1) IL238627B (enExample)
IN (1) IN2015DN03814A (enExample)
LT (1) LT2917232T (enExample)
MX (1) MX350777B (enExample)
MY (1) MY176708A (enExample)
NZ (1) NZ708812A (enExample)
PH (1) PH12015501033B1 (enExample)
PL (1) PL2917232T3 (enExample)
PT (1) PT2917232T (enExample)
RS (1) RS56069B1 (enExample)
SG (1) SG11201503657UA (enExample)
SI (1) SI2917232T1 (enExample)
WO (1) WO2014072958A1 (enExample)
ZA (1) ZA201503127B (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018127830A1 (en) 2017-01-04 2018-07-12 Apitope International Nv S-arrestin peptides and therapeutic uses thereof
US11986536B2 (en) 2019-03-23 2024-05-21 Ablevia Biotech Gmbh Compound for the sequestration of undesirable antibodies in a patient
EP3715374A1 (en) 2019-03-23 2020-09-30 Ablevia biotech GmbH Compound for the sequestration of undesirable antibodies in a patient
GB201909774D0 (en) * 2019-07-08 2019-08-21 Apitope Tech Bristol Limited Method
WO2022063887A1 (en) 2020-09-23 2022-03-31 Ablevia Biotech Gmbh Compound for increasing the efficacy of factor viii replacement therapy

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1918298T3 (da) 2000-08-21 2010-11-29 Apitope Technology Bristol Ltd Peptid
WO2002060917A2 (en) * 2000-12-01 2002-08-08 Regents Of The University Of Minnesota Method to treat hemophilia
FR2842812A1 (fr) * 2002-07-26 2004-01-30 Pf Medicament Procede de solubilisation de peptides hydrophobes et leur utilisation pour generer une reponse de type ctl antitumorale ou anti-infectueuse
JP2006188507A (ja) * 2004-12-10 2006-07-20 Tokyo Univ Of Agriculture & Technology 蛋白質の溶解度向上方法
ES2386462T3 (es) * 2005-10-28 2012-08-21 Boehringer Ingelheim International Gmbh Ensayo de la actividad NS2/3 del virus de la hepatitis C
GB0723712D0 (en) * 2007-12-04 2008-01-16 Apitope Technology Bristol Ltd Peptides
GB0801513D0 (en) * 2008-01-28 2008-03-05 Circassia Ltd Peptides from factor VIII
GB0908515D0 (en) * 2009-05-18 2009-06-24 Apitope Technology Bristol Ltd Peptide
CA2780763A1 (en) * 2009-11-13 2011-05-19 Puget Sound Blood Center Factor viii b cell epitope variants having reduced immunogenicity
US8969524B2 (en) * 2010-10-27 2015-03-03 Baxter International Inc. FVIII peptides for immune tolerance induction and immunodiagnostics

Also Published As

Publication number Publication date
BR112015010625A2 (pt) 2017-08-22
HUE033586T2 (hu) 2017-12-28
US20150306192A1 (en) 2015-10-29
PH12015501033A1 (en) 2015-07-27
AU2013343024B2 (en) 2017-06-01
SG11201503657UA (en) 2015-06-29
DK2917232T3 (en) 2017-06-12
CA2890835C (en) 2021-11-23
IN2015DN03814A (enExample) 2015-10-02
HRP20170794T1 (hr) 2017-08-11
NZ708812A (en) 2019-03-29
RS56069B1 (sr) 2017-10-31
KR20150084852A (ko) 2015-07-22
PT2917232T (pt) 2017-06-09
PL2917232T3 (pl) 2017-09-29
AU2013343024A1 (en) 2015-05-21
US20210346476A1 (en) 2021-11-11
SI2917232T1 (sl) 2017-07-31
PH12015501033B1 (en) 2015-07-27
EA201590927A1 (ru) 2015-10-30
EP2917232B1 (en) 2017-03-01
ZA201503127B (en) 2016-10-26
CA2890835A1 (en) 2014-05-15
EA036483B1 (ru) 2020-11-16
CN104903347A (zh) 2015-09-09
LT2917232T (lt) 2017-06-26
EP2917232A1 (en) 2015-09-16
WO2014072958A8 (en) 2016-10-13
MY176708A (en) 2020-08-19
ES2626881T3 (es) 2017-07-26
HK1209138A1 (en) 2016-03-24
WO2014072958A1 (en) 2014-05-15
IL238627B (en) 2018-12-31
BR112015010625B1 (pt) 2023-03-07
IL238627A0 (en) 2015-06-30
MX350777B (es) 2017-09-15
CY1119164T1 (el) 2018-02-14
KR102165486B1 (ko) 2020-10-15
CN104903347B (zh) 2020-02-21
MX2015005973A (es) 2015-09-16
JP2016501182A (ja) 2016-01-18

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