HRP20150612T1 - Postupci i pripravci koji sadrže supramolekulske konstrukte - Google Patents
Postupci i pripravci koji sadrže supramolekulske konstrukte Download PDFInfo
- Publication number
- HRP20150612T1 HRP20150612T1 HRP20150612TT HRP20150612T HRP20150612T1 HR P20150612 T1 HRP20150612 T1 HR P20150612T1 HR P20150612T T HRP20150612T T HR P20150612TT HR P20150612 T HRP20150612 T HR P20150612T HR P20150612 T1 HRP20150612 T1 HR P20150612T1
- Authority
- HR
- Croatia
- Prior art keywords
- seq
- antibody
- antigenic
- active fragment
- antibody according
- Prior art date
Links
- 238000000034 method Methods 0.000 title claims 4
- 239000000203 mixture Substances 0.000 title 1
- 230000000890 antigenic effect Effects 0.000 claims 13
- 108090000765 processed proteins & peptides Proteins 0.000 claims 9
- 239000012634 fragment Substances 0.000 claims 7
- 229920001223 polyethylene glycol Polymers 0.000 claims 6
- 208000012902 Nervous system disease Diseases 0.000 claims 5
- 208000025966 Neurological disease Diseases 0.000 claims 5
- 239000002202 Polyethylene glycol Substances 0.000 claims 4
- 239000000835 fiber Substances 0.000 claims 4
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 3
- 125000003275 alpha amino acid group Chemical group 0.000 claims 3
- 108010064397 amyloid beta-protein (1-40) Proteins 0.000 claims 3
- 239000002502 liposome Substances 0.000 claims 3
- 208000024827 Alzheimer disease Diseases 0.000 claims 2
- 108010090849 Amyloid beta-Peptides Proteins 0.000 claims 2
- 102000013455 Amyloid beta-Peptides Human genes 0.000 claims 2
- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 claims 2
- 239000004472 Lysine Substances 0.000 claims 2
- 241001465754 Metazoa Species 0.000 claims 2
- 108010064539 amyloid beta-protein (1-42) Proteins 0.000 claims 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 239000000427 antigen Substances 0.000 claims 1
- 102000036639 antigens Human genes 0.000 claims 1
- 108091007433 antigens Proteins 0.000 claims 1
- 230000006907 apoptotic process Effects 0.000 claims 1
- 230000000740 bleeding effect Effects 0.000 claims 1
- 210000004556 brain Anatomy 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000035475 disorder Diseases 0.000 claims 1
- 230000003053 immunization Effects 0.000 claims 1
- 238000000338 in vitro Methods 0.000 claims 1
- 230000005764 inhibitory process Effects 0.000 claims 1
- 125000003588 lysine group Chemical group [H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])(N([H])[H])C(*)=O 0.000 claims 1
- 230000002503 metabolic effect Effects 0.000 claims 1
- 230000035945 sensitivity Effects 0.000 claims 1
- 230000000638 stimulation Effects 0.000 claims 1
- 230000007704 transition Effects 0.000 claims 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0007—Nervous system antigens; Prions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/385—Haptens or antigens, bound to carriers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4711—Alzheimer's disease; Amyloid plaque core protein
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6093—Synthetic polymers, e.g. polyethyleneglycol [PEG], Polymers or copolymers of (D) glutamate and (D) lysine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Toxicology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Neurology (AREA)
- Mycology (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/783,975 US20040242845A1 (en) | 2003-02-21 | 2004-02-20 | Methods and compositions comprising supramolecular antigenic constructs and antibodies elicited against them |
| US10/958,211 US8663650B2 (en) | 2003-02-21 | 2004-10-04 | Methods and compositions comprising supramolecular constructs |
| EP12153152.9A EP2465533B1 (en) | 2004-02-20 | 2005-02-22 | Methods and compositions comprising supramolecular constructs |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20150612T1 true HRP20150612T1 (hr) | 2015-07-03 |
Family
ID=46395388
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HRP20150612TT HRP20150612T1 (hr) | 2004-02-20 | 2015-06-08 | Postupci i pripravci koji sadrže supramolekulske konstrukte |
Country Status (11)
| Country | Link |
|---|---|
| JP (1) | JP4934433B2 (es) |
| KR (1) | KR101277004B1 (es) |
| CY (1) | CY1116316T1 (es) |
| DK (1) | DK2465533T3 (es) |
| ES (2) | ES2385226T3 (es) |
| HK (2) | HK1130698A1 (es) |
| HR (1) | HRP20150612T1 (es) |
| HU (1) | HUE025186T2 (es) |
| PT (1) | PT2465533E (es) |
| RS (1) | RS54074B1 (es) |
| SI (1) | SI2465533T1 (es) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUE055739T2 (hu) * | 2009-03-18 | 2021-12-28 | Ac Immune Sa | Eljárás terápiás alkalmazásra |
| EP2632434A1 (en) | 2010-10-26 | 2013-09-04 | AC Immune S.A. | Liposome-based construct comprising a peptide modified through hydrophobic moieties |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6187335B1 (en) * | 1997-12-31 | 2001-02-13 | Orasomal Technologies, Inc. | Polymerizable fatty acids, phospholipids and polymerized liposomes therefrom |
| AU2600499A (en) * | 1998-02-13 | 1999-08-30 | Arch Development Corporation | Methods and compositions comprising the use of blocked b-amyloid peptide |
| AU781729B2 (en) * | 1999-12-22 | 2005-06-09 | Nektar Therapeutics | Method for the preparation of 1-benzotriazolyl carbonate esters of poly(ethylene glycol) |
-
2005
- 2005-02-22 HU HUE12153152A patent/HUE025186T2/en unknown
- 2005-02-22 KR KR1020127019675A patent/KR101277004B1/ko active IP Right Grant
- 2005-02-22 JP JP2006554250A patent/JP4934433B2/ja active Active
- 2005-02-22 PT PT121531529T patent/PT2465533E/pt unknown
- 2005-02-22 DK DK12153152.9T patent/DK2465533T3/en active
- 2005-02-22 ES ES05723323T patent/ES2385226T3/es active Active
- 2005-02-22 RS RS20150393A patent/RS54074B1/en unknown
- 2005-02-22 SI SI200531972T patent/SI2465533T1/sl unknown
- 2005-02-22 ES ES12153152.9T patent/ES2539262T3/es active Active
-
2009
- 2009-10-14 HK HK09109498.9A patent/HK1130698A1/xx unknown
-
2012
- 2012-12-20 HK HK12113161.2A patent/HK1172260A1/xx unknown
-
2015
- 2015-05-25 CY CY20151100465T patent/CY1116316T1/el unknown
- 2015-06-08 HR HRP20150612TT patent/HRP20150612T1/hr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES2385226T9 (es) | 2013-10-10 |
| KR101277004B1 (ko) | 2013-06-24 |
| JP2007527870A (ja) | 2007-10-04 |
| CY1116316T1 (el) | 2017-02-08 |
| JP4934433B2 (ja) | 2012-05-16 |
| HUE025186T2 (en) | 2016-02-29 |
| HK1130698A1 (en) | 2010-01-08 |
| SI2465533T1 (sl) | 2015-07-31 |
| HK1172260A1 (en) | 2013-04-19 |
| ES2539262T3 (es) | 2015-06-29 |
| ES2385226T3 (es) | 2012-07-19 |
| KR20120097546A (ko) | 2012-09-04 |
| DK2465533T3 (en) | 2015-04-20 |
| PT2465533E (pt) | 2015-06-24 |
| RS54074B1 (en) | 2015-10-30 |
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