HRP20130941T1 - Citratna sol 9e-15-(2-pirolidin-1-iletoksi)-7,12,25-trioksa-19,21,24-triazatetraciklo[18.3.1.1(2,5).1(14,18)]heksakoza-1(24),2,4,9,14,16,18(26),20,22-nonaena - Google Patents

Citratna sol 9e-15-(2-pirolidin-1-iletoksi)-7,12,25-trioksa-19,21,24-triazatetraciklo[18.3.1.1(2,5).1(14,18)]heksakoza-1(24),2,4,9,14,16,18(26),20,22-nonaena Download PDF

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Publication number
HRP20130941T1
HRP20130941T1 HRP20130941AT HRP20130941T HRP20130941T1 HR P20130941 T1 HRP20130941 T1 HR P20130941T1 HR P20130941A T HRP20130941A T HR P20130941AT HR P20130941 T HRP20130941 T HR P20130941T HR P20130941 T1 HRP20130941 T1 HR P20130941T1
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HR
Croatia
Prior art keywords
salt
scale
ray diffraction
salt according
triazatetracyclo
Prior art date
Application number
HRP20130941AT
Other languages
English (en)
Croatian (hr)
Inventor
Brian Dymock
Cheng Hsia Angeline Lee
Anthony Deodaunia William
Original Assignee
Cell Therapeutics, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cell Therapeutics, Inc. filed Critical Cell Therapeutics, Inc.
Publication of HRP20130941T1 publication Critical patent/HRP20130941T1/hr

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/18Bridged systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
HRP20130941AT 2009-07-15 2010-07-14 Citratna sol 9e-15-(2-pirolidin-1-iletoksi)-7,12,25-trioksa-19,21,24-triazatetraciklo[18.3.1.1(2,5).1(14,18)]heksakoza-1(24),2,4,9,14,16,18(26),20,22-nonaena HRP20130941T1 (hr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US22560909P 2009-07-15 2009-07-15
PCT/SG2010/000265 WO2011008172A1 (en) 2009-07-15 2010-07-14 9e-15-(2-pyrrolidin-1-yl-ethoxy)-7,12,25-trioxa-19,21,24-triaza- tetracyclo[18.3.1.1(2,5).1(14)18)]hexacosa-1(24),2,4,9,14,16,18(26),20,22-nonaene citrate salt

Publications (1)

Publication Number Publication Date
HRP20130941T1 true HRP20130941T1 (hr) 2013-11-08

Family

ID=42790728

Family Applications (1)

Application Number Title Priority Date Filing Date
HRP20130941AT HRP20130941T1 (hr) 2009-07-15 2010-07-14 Citratna sol 9e-15-(2-pirolidin-1-iletoksi)-7,12,25-trioksa-19,21,24-triazatetraciklo[18.3.1.1(2,5).1(14,18)]heksakoza-1(24),2,4,9,14,16,18(26),20,22-nonaena

Country Status (18)

Country Link
US (1) US9062074B2 (https=)
EP (1) EP2454266B1 (https=)
JP (2) JP6013911B2 (https=)
CN (1) CN102762577B (https=)
AR (2) AR077483A1 (https=)
BR (1) BR112012000750B1 (https=)
CA (1) CA2768210C (https=)
DK (1) DK2454266T3 (https=)
ES (1) ES2429525T3 (https=)
HR (1) HRP20130941T1 (https=)
MX (1) MX2012000680A (https=)
PL (1) PL2454266T3 (https=)
PT (1) PT2454266E (https=)
RU (1) RU2543721C2 (https=)
SI (1) SI2454266T1 (https=)
SM (1) SMT201300112B (https=)
TW (1) TWI537276B (https=)
WO (1) WO2011008172A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113559075A (zh) 2014-11-17 2021-10-29 康泰科思特生物制药公司 奥那司酮延长释放组合物和方法
AU2016326657B2 (en) 2015-09-25 2019-10-24 Context Biopharma, Inc. Methods of making onapristone intermediates
EP3389632A4 (en) 2015-12-15 2019-11-06 Context Biopharma Inc. AMORPHIC ONAPRISTON COMPOSITIONS AND METHOD FOR THE PRODUCTION THEREOF
WO2018102369A1 (en) 2016-11-30 2018-06-07 Arno Therapeutics, Inc. Methods for onapristone synthesis dehydration and deprotection

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY110603A (en) * 1993-05-27 1998-08-29 Novartis Ag Tetrahydropyran derivatives
WO2004078682A2 (en) * 2003-03-05 2004-09-16 Irm Llc Cyclic compounds and compositions as protein kinase inhibitors
NZ568325A (en) 2005-11-16 2011-05-27 S Bio Pte Ltd Macrocyclic oxygen linked pyrimidine derivatives

Also Published As

Publication number Publication date
CA2768210A1 (en) 2011-01-20
DK2454266T3 (da) 2013-09-08
CA2768210C (en) 2017-08-15
EP2454266A1 (en) 2012-05-23
CN102762577A (zh) 2012-10-31
AR114987A2 (es) 2020-11-11
RU2012105044A (ru) 2013-08-20
BR112012000750B1 (pt) 2021-05-25
JP2015164941A (ja) 2015-09-17
TWI537276B (zh) 2016-06-11
JP2012533539A (ja) 2012-12-27
AR077483A1 (es) 2011-08-31
SMT201300112B (it) 2013-11-08
RU2543721C2 (ru) 2015-03-10
SI2454266T1 (sl) 2013-10-30
BR112012000750A2 (pt) 2016-08-09
ES2429525T3 (es) 2013-11-15
BR112012000750A8 (pt) 2018-02-06
US20120196876A1 (en) 2012-08-02
CN102762577B (zh) 2015-01-07
JP6013911B2 (ja) 2016-10-25
WO2011008172A1 (en) 2011-01-20
EP2454266B1 (en) 2013-07-10
US9062074B2 (en) 2015-06-23
MX2012000680A (es) 2012-02-28
HK1178159A1 (en) 2013-09-06
PT2454266E (pt) 2013-10-10
TW201107336A (en) 2011-03-01
PL2454266T3 (pl) 2014-01-31

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