HRP20120130T1 - Upotreba 4-ciklopropilmetoksi-n-(3,5-diklor-1-oksido-4-piridin-4-il)-5-(metoksi)piridin-2-karboksamida u liječenju ozljeda lubanje - Google Patents
Upotreba 4-ciklopropilmetoksi-n-(3,5-diklor-1-oksido-4-piridin-4-il)-5-(metoksi)piridin-2-karboksamida u liječenju ozljeda lubanje Download PDFInfo
- Publication number
- HRP20120130T1 HRP20120130T1 HR20120130T HRP20120130T HRP20120130T1 HR P20120130 T1 HRP20120130 T1 HR P20120130T1 HR 20120130 T HR20120130 T HR 20120130T HR P20120130 T HRP20120130 T HR P20120130T HR P20120130 T1 HRP20120130 T1 HR P20120130T1
- Authority
- HR
- Croatia
- Prior art keywords
- oxidopyridin
- cyclopropylmethoxy
- carboxamide
- dichloro
- pyridine
- Prior art date
Links
- 208000014674 injury Diseases 0.000 title 1
- IBBMAWULFFBRKK-UHFFFAOYSA-N picolinamide Chemical compound NC(=O)C1=CC=CC=N1 IBBMAWULFFBRKK-UHFFFAOYSA-N 0.000 title 1
- 230000008733 trauma Effects 0.000 title 1
- 239000002253 acid Substances 0.000 claims abstract 2
- 208000029028 brain injury Diseases 0.000 claims abstract 2
- 150000001875 compounds Chemical class 0.000 claims abstract 2
- 239000003814 drug Substances 0.000 claims abstract 2
- 150000003839 salts Chemical class 0.000 claims abstract 2
- 239000012453 solvate Substances 0.000 claims abstract 2
- BRUDLLFMCVQZFT-UHFFFAOYSA-N COC1=CN=C(C(=O)NC=2C(=C[N+]([O-])=CC=2Cl)Cl)C=C1OCC1CC1 Chemical compound COC1=CN=C(C(=O)NC=2C(=C[N+]([O-])=CC=2Cl)Cl)C=C1OCC1CC1 BRUDLLFMCVQZFT-UHFFFAOYSA-N 0.000 claims 2
- 229940079593 drug Drugs 0.000 claims 1
- -1 3,5-dichloro-1-oxidopyridin-4-yl Chemical group 0.000 abstract 1
- 239000002585 base Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0702852A FR2915099B1 (fr) | 2007-04-19 | 2007-04-19 | Utilisation du 4-cyclopropylmethoxy-n-(3,5-dichloro-1-oxydo- pyridin-4-yl)-5-(methoxy)pyridine-2-carboxamide pour le traitement des traumatismes craniens |
| PCT/FR2008/000531 WO2008145838A2 (fr) | 2007-04-19 | 2008-04-16 | Utilisation du 4-cyclopropylmethoxy-n-(3,5-dichloro-1-oxydo-4- pyridin-4-yl)-5-(methoxy)pyridine-2-carboxamide pour le traitement des traumatismes craniens |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20120130T1 true HRP20120130T1 (hr) | 2012-03-31 |
Family
ID=38819821
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HR20120130T HRP20120130T1 (hr) | 2007-04-19 | 2012-02-07 | Upotreba 4-ciklopropilmetoksi-n-(3,5-diklor-1-oksido-4-piridin-4-il)-5-(metoksi)piridin-2-karboksamida u liječenju ozljeda lubanje |
Country Status (34)
| Country | Link |
|---|---|
| US (1) | US9393236B2 (me) |
| EP (1) | EP2146713B1 (me) |
| JP (1) | JP5386476B2 (me) |
| KR (1) | KR101460828B1 (me) |
| CN (1) | CN101663036B (me) |
| AR (1) | AR066105A1 (me) |
| AT (1) | ATE532513T1 (me) |
| AU (1) | AU2008257319B2 (me) |
| BR (1) | BRPI0810423A2 (me) |
| CA (1) | CA2684171C (me) |
| CL (1) | CL2008001135A1 (me) |
| CO (1) | CO6140028A2 (me) |
| CY (1) | CY1112282T1 (me) |
| DK (1) | DK2146713T3 (me) |
| EA (1) | EA015503B1 (me) |
| ES (1) | ES2376023T3 (me) |
| FR (1) | FR2915099B1 (me) |
| HK (1) | HK1141724A1 (me) |
| HR (1) | HRP20120130T1 (me) |
| IL (1) | IL201447A (me) |
| JO (1) | JO2861B1 (me) |
| MA (1) | MA31368B1 (me) |
| ME (2) | ME01273B (me) |
| MX (1) | MX2009011214A (me) |
| MY (1) | MY147207A (me) |
| NZ (1) | NZ580484A (me) |
| PA (1) | PA8776701A1 (me) |
| PL (1) | PL2146713T3 (me) |
| PT (1) | PT2146713E (me) |
| RS (1) | RS52130B (me) |
| SI (1) | SI2146713T1 (me) |
| TW (1) | TWI423800B (me) |
| UY (1) | UY31034A1 (me) |
| WO (1) | WO2008145838A2 (me) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2015006807A (es) * | 2012-11-28 | 2016-01-14 | Sanofi Sa | Metodo de preparacion de formas cristalinas de la 4-(ciclopropilmetoxi)-n-(3,5-dicloro-1-oxidopiridin-4-il)-5-metox ipiridin-2-carboxamida y sus formas cristalinas. |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US1273326A (en) * | 1917-08-22 | 1918-07-23 | George H Bugenhagen | Transmission mechanism. |
| US4193926A (en) * | 1974-03-20 | 1980-03-18 | Schering Aktiengesellschaft | 4-(Polyalkoxy phenyl)-2-pyrrolidones |
| ATE218549T1 (de) * | 1993-07-28 | 2002-06-15 | Aventis Pharma Ltd | Verbindungen als pde iv und tnf inhibitoren |
| GB9401460D0 (en) * | 1994-01-26 | 1994-03-23 | Rhone Poulenc Rorer Ltd | Compositions of matter |
| GB9507297D0 (en) * | 1995-04-07 | 1995-05-31 | Rh Ne Poulenc Rorer Limited | New composition of matter |
| US6177077B1 (en) * | 1999-02-24 | 2001-01-23 | Edward L. Tobinick | TNT inhibitors for the treatment of neurological disorders |
| PL357340A1 (en) * | 1999-06-07 | 2004-07-26 | Warner-Lambert Company | Tricyclic analgesics |
| ES2239063T3 (es) * | 1999-12-23 | 2005-09-16 | Icos Corporation | Inhibidores de la fosfodiesterasa ciclica especifica de amp. |
| US20030069169A1 (en) * | 2001-03-02 | 2003-04-10 | Macor John E. | Co-administration of melanocortin receptor agonist and phosphodiesterase inhibitor for treatment of cyclic-AMP associated disorders |
| WO2004005258A1 (en) | 2002-07-02 | 2004-01-15 | Merck Frosst Canada & Co. | Di-aryl-substituted-ethane pyridone pde4 inhibitors |
| US20060083714A1 (en) * | 2003-01-27 | 2006-04-20 | Warner James M | Combination of a pde iv inhibitor and a tnf-alpha antagonist |
| EP1685109A2 (en) | 2003-10-07 | 2006-08-02 | Renovis, Inc. | Amide compounds as ion channel ligands and uses thereof |
| US20070049611A1 (en) * | 2005-06-10 | 2007-03-01 | Talamas Francisco X | Phosphodiesterase 4 inhibitors |
| US20070021451A1 (en) * | 2005-07-20 | 2007-01-25 | Hamamatsu University School Of Medicine | Method for preventing or treating neurologic damage after spinal cord injury |
| FR2915098B1 (fr) | 2007-04-19 | 2009-06-05 | Sanofi Aventis Sa | Utilisation du 4-cyclopropylmethoxy-n-(3,5-dichloro-1-oxydo- pyridin-4-yl)-5-(methoxy)pyridine-2-carboxamide pour le traitement des traumatismes de la moelle epiniere |
-
2007
- 2007-04-19 FR FR0702852A patent/FR2915099B1/fr not_active Expired - Fee Related
-
2008
- 2008-04-15 PA PA20088776701A patent/PA8776701A1/es unknown
- 2008-04-16 MX MX2009011214A patent/MX2009011214A/es active IP Right Grant
- 2008-04-16 BR BRPI0810423-9A2A patent/BRPI0810423A2/pt not_active IP Right Cessation
- 2008-04-16 NZ NZ580484A patent/NZ580484A/en not_active IP Right Cessation
- 2008-04-16 DK DK08787960.7T patent/DK2146713T3/da active
- 2008-04-16 ME MEP-2012-15A patent/ME01273B/me unknown
- 2008-04-16 AT AT08787960T patent/ATE532513T1/de active
- 2008-04-16 ES ES08787960T patent/ES2376023T3/es active Active
- 2008-04-16 ME MEP-2009-306A patent/ME00938B/me unknown
- 2008-04-16 CA CA2684171A patent/CA2684171C/fr not_active Expired - Fee Related
- 2008-04-16 CN CN2008800127185A patent/CN101663036B/zh not_active Expired - Fee Related
- 2008-04-16 PL PL08787960T patent/PL2146713T3/pl unknown
- 2008-04-16 EP EP08787960A patent/EP2146713B1/fr active Active
- 2008-04-16 EA EA200970968A patent/EA015503B1/ru not_active IP Right Cessation
- 2008-04-16 WO PCT/FR2008/000531 patent/WO2008145838A2/fr active Application Filing
- 2008-04-16 AU AU2008257319A patent/AU2008257319B2/en not_active Ceased
- 2008-04-16 RS RS20120041A patent/RS52130B/en unknown
- 2008-04-16 KR KR1020097021592A patent/KR101460828B1/ko not_active IP Right Cessation
- 2008-04-16 MY MYPI20094365A patent/MY147207A/en unknown
- 2008-04-16 JP JP2010503546A patent/JP5386476B2/ja not_active Expired - Fee Related
- 2008-04-16 PT PT08787960T patent/PT2146713E/pt unknown
- 2008-04-16 SI SI200830535T patent/SI2146713T1/sl unknown
- 2008-04-17 TW TW097113999A patent/TWI423800B/zh not_active IP Right Cessation
- 2008-04-17 JO JO2008184A patent/JO2861B1/en active
- 2008-04-18 CL CL2008001135A patent/CL2008001135A1/es unknown
- 2008-04-18 UY UY31034A patent/UY31034A1/es not_active Application Discontinuation
- 2008-04-18 AR ARP080101599A patent/AR066105A1/es unknown
-
2009
- 2009-10-05 US US12/573,322 patent/US9393236B2/en not_active Expired - Fee Related
- 2009-10-11 IL IL201447A patent/IL201447A/en not_active IP Right Cessation
- 2009-10-19 CO CO09116642A patent/CO6140028A2/es unknown
- 2009-11-10 MA MA32334A patent/MA31368B1/fr unknown
-
2010
- 2010-08-31 HK HK10108260.4A patent/HK1141724A1/xx not_active IP Right Cessation
-
2012
- 2012-01-26 CY CY20121100094T patent/CY1112282T1/el unknown
- 2012-02-07 HR HR20120130T patent/HRP20120130T1/hr unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CA2918938C (en) | Substituted aminopyrimidine compounds and methods of use | |
| GEP201706780B (en) | Substituted 2-aza-bicyclo [2.2.1]heptane-3-carboxylic acid (benzyl-cyano-methyl)-amides inhibitors of cathepsin c | |
| WO2014120808A8 (en) | Pyridone amides as modulators of sodium channels | |
| MX2009011997A (es) | Derivados de pirrolopirimidin-7-ona y su uso como farmaceuticos. | |
| PT2150530E (pt) | Derivados de sulfonamida substituídos | |
| MD4490C1 (ro) | Noi compuşi de indolizină, procedeu de obţinere a lor şi compoziţii farmaceutice care îi conţin | |
| IN2012DN01453A (me) | ||
| BR112014025564B8 (pt) | composto heterocíclico contendo nitrogênio ou sal do mesmo, composição farmacêutica e uso da mesma | |
| MY143568A (en) | 11b-hsd1 inhibitors for the treatment of diabetes | |
| WO2006077025A3 (en) | Morpholines as 5ht2c agonists | |
| EA201100358A1 (ru) | Дабигатран для чрескожной хирургической катетеризации сердца | |
| MX2010001574A (es) | Ligandos del receptor cannabinoide. | |
| GEP20166488B (en) | Co-crystals and salts of ccr3-inhibitors | |
| MX2009004017A (es) | Usos de los compuestos carboxi-amido triazol y sus sales. | |
| MX2010009395A (es) | Agonistas de receptores muscarinicos, composiciones, metodos de tratamiento de los mismos, y procesos para preparacion de los mismos. | |
| MX2010009756A (es) | Agonistas de receptores muscarinicos, composiciones, metodos de tratamiento de los mismos, y proceso para preparacion de los mismos. | |
| MX2012001529A (es) | Derivados de 3-heteroaril-metil-imidazo-[1,2-b]-piridazin-6-ilo como moduladores de cinasa de tirosina c-met. | |
| PH12015501945B1 (en) | Formulations of organic compounds | |
| TW200626581A (en) | Compounds, compositions containing them, preparation thereof and uses thereof | |
| GB0602951D0 (en) | Organic Compounds | |
| HRP20110459T1 (hr) | Upotreba 4-ciklopropilmetoksi-n-(3,5-diklor-1-oksidopiridin-4-il)-5-(metoksi)piridin-2-karboksamida u liječenju ozljeda kralježnične moždine | |
| HRP20120130T1 (hr) | Upotreba 4-ciklopropilmetoksi-n-(3,5-diklor-1-oksido-4-piridin-4-il)-5-(metoksi)piridin-2-karboksamida u liječenju ozljeda lubanje | |
| NZ592378A (en) | Choline and tromethamine salt of licofelone | |
| RS51869B (en) | USE OF 4-CYCLOPROPYLMETOXY-N- (3,5-DICHLORO-1-OXIDO-PYRIDIN-4-IL) -5- (METHOXY) PYRIDINE-2-CARBOXAMIDE FOR THE TREATMENT OF MOTOR DISORDERS RELATED TO PARKINSON'S DISEASE | |
| HRP20130983T1 (hr) | Derivati arilciklopropilacetamida, korisni kao aktivatori glukokinaze |