PL357340A1 - Tricyclic analgesics - Google Patents

Tricyclic analgesics

Info

Publication number
PL357340A1
PL357340A1 PL00357340A PL35734000A PL357340A1 PL 357340 A1 PL357340 A1 PL 357340A1 PL 00357340 A PL00357340 A PL 00357340A PL 35734000 A PL35734000 A PL 35734000A PL 357340 A1 PL357340 A1 PL 357340A1
Authority
PL
Poland
Prior art keywords
analgesics
tricyclic
tricyclic analgesics
Prior art date
Application number
PL00357340A
Other languages
Polish (pl)
Inventor
Alain Calvet
Henri Jacobelli
Jocelyne Puaud
Francois J. Roman
Jacques Hamon
Agnes Grouhel
Original Assignee
Warner-Lambert Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner-Lambert Company filed Critical Warner-Lambert Company
Publication of PL357340A1 publication Critical patent/PL357340A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/20—Spiro-condensed ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/438—The ring being spiro-condensed with carbocyclic or heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Hydrogenated Pyridines (AREA)
PL00357340A 1999-06-07 2000-06-07 Tricyclic analgesics PL357340A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13786899P 1999-06-07 1999-06-07
PCT/EP2000/005783 WO2000075116A2 (en) 1999-06-07 2000-06-07 Tricyclic analgesics

Publications (1)

Publication Number Publication Date
PL357340A1 true PL357340A1 (en) 2004-07-26

Family

ID=22479397

Family Applications (1)

Application Number Title Priority Date Filing Date
PL00357340A PL357340A1 (en) 1999-06-07 2000-06-07 Tricyclic analgesics

Country Status (21)

Country Link
EP (1) EP1235808A2 (en)
JP (1) JP2003513006A (en)
KR (1) KR20020010923A (en)
CN (1) CN1635998A (en)
AP (1) AP2001002356A0 (en)
AU (1) AU6428400A (en)
BG (1) BG106162A (en)
BR (1) BR0011427A (en)
CA (1) CA2376076A1 (en)
EA (1) EA200101117A1 (en)
HR (1) HRP20010913A2 (en)
HU (1) HUP0203317A2 (en)
IL (1) IL146755A0 (en)
IS (1) IS6175A (en)
MA (1) MA26795A1 (en)
MX (1) MXPA01012694A (en)
NO (1) NO20015966L (en)
PL (1) PL357340A1 (en)
SK (1) SK17512001A3 (en)
TR (1) TR200103531T2 (en)
WO (1) WO2000075116A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030045449A1 (en) * 2001-08-15 2003-03-06 Pfizer, Inc. Pharmaceutical combinations for the treatment of neurodegenerative diseases
FR2915099B1 (en) * 2007-04-19 2009-06-05 Sanofi Aventis Sa USE OF 4-CYCLOPROPYLMETHOXY-N- (3,5-DICHLORO-1-OXYDO-PYRIDIN-4-YL) -5- (METHOXY) PYRIDINE-2-CARBOXAMIDE FOR THE TREATMENT OF CRANIAL TRAUMATISM
US8916565B2 (en) * 2011-02-02 2014-12-23 Vertex Pharmaceuticals Incorporated Pyrrolopyrazine-spirocyclic piperidine amides as modulators of ion channels
CN115872873A (en) * 2022-12-29 2023-03-31 上海泰坦科技股份有限公司 Recrystallization purification method of bis (2-bromoethyl) amine hydrobromide

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8917069D0 (en) * 1989-07-26 1989-09-13 Merck Sharp & Dohme Therapeutic agents
IL96507A0 (en) * 1989-12-08 1991-08-16 Merck & Co Inc Nitrogen-containing spirocycles and pharmaceutical compositions containing them
ATE169001T1 (en) * 1993-01-28 1998-08-15 Merck & Co Inc SUBSTITUTED SPIRO-AZARINGENE AS TACHYKININ RECEPTOR ANTAGONISTS
US5439914A (en) * 1994-02-18 1995-08-08 Merck & Co., Inc. Spirocycles
WO1998025604A1 (en) * 1996-12-13 1998-06-18 Merck & Co., Inc. Spiro-substituted azacycles as modulators of chemokine receptor activity
US6013644A (en) * 1997-12-12 2000-01-11 Merck & Co., Inc. Spiro-substituted azacycles as modulators of chemokine receptor activity

Also Published As

Publication number Publication date
NO20015966D0 (en) 2001-12-06
AU6428400A (en) 2000-12-28
HRP20010913A2 (en) 2003-04-30
AP2001002356A0 (en) 2001-12-31
CN1635998A (en) 2005-07-06
IL146755A0 (en) 2002-07-25
MA26795A1 (en) 2004-12-20
TR200103531T2 (en) 2002-06-21
EP1235808A2 (en) 2002-09-04
SK17512001A3 (en) 2002-11-06
BR0011427A (en) 2002-03-26
WO2000075116A3 (en) 2002-07-04
EA200101117A1 (en) 2002-06-27
CA2376076A1 (en) 2000-12-14
IS6175A (en) 2001-11-23
NO20015966L (en) 2001-12-06
HUP0203317A2 (en) 2003-02-28
MXPA01012694A (en) 2003-10-15
WO2000075116A2 (en) 2000-12-14
JP2003513006A (en) 2003-04-08
KR20020010923A (en) 2002-02-06
BG106162A (en) 2002-05-31

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Legal Events

Date Code Title Description
REFS Decisions on refusal to grant patents (taken after the publication of the particulars of the applications)