HRP20100399T1 - Oralno dezintegrirajući pripravak olanzapina ili donepezila - Google Patents
Oralno dezintegrirajući pripravak olanzapina ili donepezila Download PDFInfo
- Publication number
- HRP20100399T1 HRP20100399T1 HR20100399T HRP20100399T HRP20100399T1 HR P20100399 T1 HRP20100399 T1 HR P20100399T1 HR 20100399 T HR20100399 T HR 20100399T HR P20100399 T HRP20100399 T HR P20100399T HR P20100399 T1 HRP20100399 T1 HR P20100399T1
- Authority
- HR
- Croatia
- Prior art keywords
- preparation according
- donepezil
- olanzapine
- active ingredient
- preparation
- Prior art date
Links
- ADEBPBSSDYVVLD-UHFFFAOYSA-N donepezil Chemical compound O=C1C=2C=C(OC)C(OC)=CC=2CC1CC(CC1)CCN1CC1=CC=CC=C1 ADEBPBSSDYVVLD-UHFFFAOYSA-N 0.000 title claims abstract 8
- 239000000203 mixture Substances 0.000 title claims abstract 5
- 229960003530 donepezil Drugs 0.000 title claims abstract 4
- KVWDHTXUZHCGIO-UHFFFAOYSA-N olanzapine Chemical compound C1CN(C)CCN1C1=NC2=CC=CC=C2NC2=C1C=C(C)S2 KVWDHTXUZHCGIO-UHFFFAOYSA-N 0.000 title claims abstract 4
- 229960005017 olanzapine Drugs 0.000 title claims abstract 4
- 239000004480 active ingredient Substances 0.000 claims abstract 5
- 238000000034 method Methods 0.000 claims abstract 4
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 claims 4
- 229930195725 Mannitol Natural products 0.000 claims 4
- 239000000378 calcium silicate Substances 0.000 claims 4
- 229910052918 calcium silicate Inorganic materials 0.000 claims 4
- OYACROKNLOSFPA-UHFFFAOYSA-N calcium;dioxido(oxo)silane Chemical compound [Ca+2].[O-][Si]([O-])=O OYACROKNLOSFPA-UHFFFAOYSA-N 0.000 claims 4
- 239000008187 granular material Substances 0.000 claims 4
- 239000000594 mannitol Substances 0.000 claims 4
- 235000010355 mannitol Nutrition 0.000 claims 4
- 150000003839 salts Chemical class 0.000 claims 3
- 239000012453 solvate Substances 0.000 claims 3
- WHNWPMSKXPGLAX-UHFFFAOYSA-N N-Vinyl-2-pyrrolidone Chemical compound C=CN1CCCC1=O WHNWPMSKXPGLAX-UHFFFAOYSA-N 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 229960003135 donepezil hydrochloride Drugs 0.000 claims 1
- XWAIAVWHZJNZQQ-UHFFFAOYSA-N donepezil hydrochloride Chemical compound [H+].[Cl-].O=C1C=2C=C(OC)C(OC)=CC=2CC1CC(CC1)CCN1CC1=CC=CC=C1 XWAIAVWHZJNZQQ-UHFFFAOYSA-N 0.000 claims 1
- 229940031703 low substituted hydroxypropyl cellulose Drugs 0.000 claims 1
- 239000000825 pharmaceutical preparation Substances 0.000 claims 1
- 229920000036 polyvinylpyrrolidone Polymers 0.000 claims 1
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 claims 1
- 229940069328 povidone Drugs 0.000 claims 1
- 238000007493 shaping process Methods 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Psychiatry (AREA)
- Biophysics (AREA)
- Hospice & Palliative Care (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP05000664A EP1681048A1 (en) | 2005-01-14 | 2005-01-14 | Orally disintegrating composition of olanzapine or donepezil |
| PCT/EP2006/000284 WO2006074951A2 (en) | 2005-01-14 | 2006-01-13 | Orally disintegrating composition of olanzapine or donepezil |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20100399T1 true HRP20100399T1 (hr) | 2010-09-30 |
Family
ID=34933289
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HR20100399T HRP20100399T1 (hr) | 2005-01-14 | 2010-07-20 | Oralno dezintegrirajući pripravak olanzapina ili donepezila |
Country Status (15)
| Country | Link |
|---|---|
| EP (2) | EP1681048A1 (sl) |
| AT (1) | ATE465719T1 (sl) |
| AU (1) | AU2006205817A1 (sl) |
| DE (1) | DE602006013940D1 (sl) |
| DK (1) | DK1845954T3 (sl) |
| EA (1) | EA013742B1 (sl) |
| ES (1) | ES2344959T3 (sl) |
| HR (1) | HRP20100399T1 (sl) |
| NO (1) | NO20074087L (sl) |
| PL (1) | PL1845954T3 (sl) |
| PT (1) | PT1845954E (sl) |
| SI (1) | SI1845954T1 (sl) |
| UA (1) | UA89394C2 (sl) |
| WO (1) | WO2006074951A2 (sl) |
| ZA (1) | ZA200706692B (sl) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7879382B2 (en) | 2005-09-30 | 2011-02-01 | Fmc Corporation | Stabilizers and compositions and products comprising same |
| DE102005060377A1 (de) * | 2005-12-16 | 2007-06-21 | Ratiopharm Gmbh | Pharmazeutische Zusammensetzung enthaltend Donepezilhydrochlorid, Tablette hieraus und Verfahren zu deren Herstellung |
| JP5535616B2 (ja) * | 2006-03-31 | 2014-07-02 | ルビコン リサーチ プライベート リミテッド | 口腔内崩壊錠剤のための直接圧縮性複合材 |
| GB0614586D0 (en) * | 2006-07-22 | 2006-08-30 | Pliva Istrazivacki Inst D O O | Pharmaceutical Formulation |
| DK2248519T3 (en) * | 2006-10-02 | 2018-01-02 | Applied Pharma Res | Non-mucoadhesive film dosage forms |
| WO2008057267A2 (en) * | 2006-10-27 | 2008-05-15 | Fmc Corporation | Co-processed microcrystalline cellulose and sugar alcohol as an excipient for tablet formulations |
| EP2133096A4 (en) | 2007-03-13 | 2011-11-16 | Dainippon Sumitomo Pharma Co | IN THE MOUTHING TABLET |
| BRPI0817927A2 (pt) | 2007-10-01 | 2015-04-07 | Lesvi Laboratorios Sl | Comprimidos orodispersiveis |
| CN101756917A (zh) * | 2008-10-24 | 2010-06-30 | 北京科信必成医药科技发展有限公司 | 盐酸多奈哌齐口腔崩解片及其制备方法 |
| EP2391350A1 (en) * | 2008-12-18 | 2011-12-07 | Ranbaxy Laboratories Limited | Atazanavir formulations |
| EP2198857A1 (en) | 2008-12-19 | 2010-06-23 | Ratiopharm GmbH | Oral dispersible tablet |
| TR200903293A1 (tr) | 2009-04-28 | 2010-11-22 | Sanovel İlaç San. Ve Ti̇c. A.Ş. | Oral yolla dağılan olanzapin tablet. |
| TR201002084A1 (tr) * | 2010-03-19 | 2011-10-21 | Sanovel İlaç Sanayi̇ Ve Ti̇caret Anoni̇m Şi̇rketi̇ | Oral yolla dağılan donepezil tablet formülasyonları ve hazırlama yöntemi |
| FR2962331B1 (fr) * | 2010-07-06 | 2020-04-24 | Ethypharm | Forme pharmaceutique pour lutter contre la soumission chimique, methode la mettant en oeuvre |
| WO2012014012A1 (es) * | 2010-07-27 | 2012-02-02 | Laboratorios Andrómaco S.A. | Procedimiento para preparar comprimidos de disolucion rapida oral que comprenden la forma i de olanzapina, los comprimidos obtenidos y su uso para el tratamiento de la esquizofrenia. |
| PL2764045T3 (pl) | 2011-10-05 | 2017-08-31 | Fmc Corporation | Kompozycja stabilizatora ze współścieranej celulozy mikrokrystalicznej i karboksymetylocelulozy, sposób wytwarzania i zastosowania |
| BR112014007366B1 (pt) | 2011-10-05 | 2020-09-15 | Dupont Nutrition Usa, Inc | Processo para fabricar uma composição estabilizadora compreendendo extrusão em duas etapas, composição estabilizadora de celulose microcristalina e produto alimentício comestível e suspensão industrial compreendendo a mesma |
| ES2628612T3 (es) | 2011-12-09 | 2017-08-03 | Fmc Corporation | Composición estabilizadora coerosionada |
| WO2014027975A2 (en) * | 2012-08-17 | 2014-02-20 | Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi | Novel orally administered pharmaceutical formulations |
| FR2999432B1 (fr) * | 2012-12-17 | 2014-12-12 | Ethypharm Sa | Comprimes orodispersibles obtenus par compression moulage |
| CN104510717B (zh) * | 2013-09-27 | 2019-02-05 | 江苏豪森药业集团有限公司 | 奥氮平口崩片及其制备方法 |
| CN108261399A (zh) * | 2016-12-30 | 2018-07-10 | 江苏豪森药业集团有限公司 | 奥氮平口腔崩解片及其制备方法 |
| CN108926543A (zh) * | 2017-05-26 | 2018-12-04 | 万全万特制药江苏有限公司 | 一种奥氮平口腔崩解片及其制备方法 |
| CN109498544A (zh) * | 2017-09-15 | 2019-03-22 | 万全万特制药江苏有限公司 | 稳定的奥氮平组合物及其制备方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1260215B1 (en) * | 2000-03-01 | 2009-07-29 | Eisai R&D Management Co., Ltd. | Rapidly disintegrable tablet containing polyvinyl alcohol |
| AU2002255196A1 (en) * | 2002-04-18 | 2003-10-27 | Dr. Reddy's Laboratories Ltd. | Rapidly dispersing solid oral compositions |
-
2005
- 2005-01-14 EP EP05000664A patent/EP1681048A1/en not_active Withdrawn
-
2006
- 2006-01-13 DK DK06701464.7T patent/DK1845954T3/da active
- 2006-01-13 AT AT06701464T patent/ATE465719T1/de active
- 2006-01-13 PT PT06701464T patent/PT1845954E/pt unknown
- 2006-01-13 WO PCT/EP2006/000284 patent/WO2006074951A2/en active Application Filing
- 2006-01-13 EP EP06701464A patent/EP1845954B1/en active Active
- 2006-01-13 AU AU2006205817A patent/AU2006205817A1/en not_active Abandoned
- 2006-01-13 UA UAA200709252A patent/UA89394C2/uk unknown
- 2006-01-13 EA EA200701462A patent/EA013742B1/ru not_active IP Right Cessation
- 2006-01-13 PL PL06701464T patent/PL1845954T3/pl unknown
- 2006-01-13 ES ES06701464T patent/ES2344959T3/es active Active
- 2006-01-13 DE DE602006013940T patent/DE602006013940D1/de active Active
- 2006-01-13 SI SI200630726T patent/SI1845954T1/sl unknown
-
2007
- 2007-08-07 NO NO20074087A patent/NO20074087L/no not_active Application Discontinuation
- 2007-08-13 ZA ZA200706692A patent/ZA200706692B/en unknown
-
2010
- 2010-07-20 HR HR20100399T patent/HRP20100399T1/hr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP1681048A1 (en) | 2006-07-19 |
| EA200701462A1 (ru) | 2008-02-28 |
| ES2344959T3 (es) | 2010-09-10 |
| EP1845954B1 (en) | 2010-04-28 |
| DK1845954T3 (da) | 2010-08-16 |
| WO2006074951A2 (en) | 2006-07-20 |
| SI1845954T1 (sl) | 2010-08-31 |
| NO20074087L (no) | 2007-10-09 |
| WO2006074951A3 (en) | 2007-04-26 |
| ZA200706692B (en) | 2008-07-30 |
| PL1845954T3 (pl) | 2010-10-29 |
| DE602006013940D1 (de) | 2010-06-10 |
| PT1845954E (pt) | 2010-08-02 |
| EP1845954A2 (en) | 2007-10-24 |
| UA89394C2 (uk) | 2010-01-25 |
| EA013742B1 (ru) | 2010-06-30 |
| ATE465719T1 (de) | 2010-05-15 |
| AU2006205817A1 (en) | 2006-07-20 |
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