HRP20100014T1 - Uporaba il-23 i il-17 antagonista u liječenju autoimune očne upalne bolesti - Google Patents
Uporaba il-23 i il-17 antagonista u liječenju autoimune očne upalne bolesti Download PDFInfo
- Publication number
- HRP20100014T1 HRP20100014T1 HR20100014T HRP20100014T HRP20100014T1 HR P20100014 T1 HRP20100014 T1 HR P20100014T1 HR 20100014 T HR20100014 T HR 20100014T HR P20100014 T HRP20100014 T HR P20100014T HR P20100014 T1 HRP20100014 T1 HR P20100014T1
- Authority
- HR
- Croatia
- Prior art keywords
- antagonist
- use according
- monoclonal antibody
- treatment
- period
- Prior art date
Links
- 230000001363 autoimmune Effects 0.000 title claims abstract 11
- 208000027866 inflammatory disease Diseases 0.000 title claims abstract 9
- 239000005557 antagonist Substances 0.000 title claims 122
- 102000013691 Interleukin-17 Human genes 0.000 claims abstract 71
- 108050003558 Interleukin-17 Proteins 0.000 claims abstract 71
- 102000013264 Interleukin-23 Human genes 0.000 claims abstract 39
- 108010065637 Interleukin-23 Proteins 0.000 claims abstract 39
- 239000000825 pharmaceutical preparation Substances 0.000 claims abstract 12
- 230000000694 effects Effects 0.000 claims abstract 3
- 238000011282 treatment Methods 0.000 claims 63
- 239000012634 fragment Substances 0.000 claims 34
- 208000024891 symptom Diseases 0.000 claims 10
- 108010076561 Interleukin-23 Subunit p19 Proteins 0.000 claims 8
- 102100036672 Interleukin-23 receptor Human genes 0.000 claims 8
- 102100036705 Interleukin-23 subunit alpha Human genes 0.000 claims 8
- 108040001844 interleukin-23 receptor activity proteins Proteins 0.000 claims 8
- 239000008194 pharmaceutical composition Substances 0.000 claims 8
- 230000008034 disappearance Effects 0.000 claims 6
- 239000003814 drug Substances 0.000 claims 6
- 229940124597 therapeutic agent Drugs 0.000 claims 6
- 102100035018 Interleukin-17 receptor A Human genes 0.000 claims 4
- 101710186083 Interleukin-17 receptor A Proteins 0.000 claims 4
- 238000003745 diagnosis Methods 0.000 claims 4
- 230000035945 sensitivity Effects 0.000 claims 4
- 102100035012 Interleukin-17 receptor C Human genes 0.000 claims 3
- 101710186068 Interleukin-17 receptor C Proteins 0.000 claims 3
- 102000008394 Immunoglobulin Fragments Human genes 0.000 claims 2
- 108010021625 Immunoglobulin Fragments Proteins 0.000 claims 2
- 206010061218 Inflammation Diseases 0.000 claims 2
- 208000018359 Systemic autoimmune disease Diseases 0.000 claims 2
- 206010046851 Uveitis Diseases 0.000 claims 2
- 230000004054 inflammatory process Effects 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 239000000041 non-steroidal anti-inflammatory agent Substances 0.000 claims 2
- 229940021182 non-steroidal anti-inflammatory drug Drugs 0.000 claims 2
- 238000011321 prophylaxis Methods 0.000 claims 2
- 150000003431 steroids Chemical class 0.000 claims 2
- 238000002560 therapeutic procedure Methods 0.000 claims 2
- 229940046728 tumor necrosis factor alpha inhibitor Drugs 0.000 claims 2
- 239000002451 tumor necrosis factor inhibitor Substances 0.000 claims 2
- 206010015943 Eye inflammation Diseases 0.000 claims 1
- 229940126601 medicinal product Drugs 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 229940126534 drug product Drugs 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US71379205P | 2005-09-01 | 2005-09-01 | |
US83731206P | 2006-08-11 | 2006-08-11 | |
PCT/US2006/033840 WO2007027761A2 (en) | 2005-09-01 | 2006-08-30 | Use of il-23 and il-17 antagonists to treat autoimmune ocular inflammatory disease |
Publications (1)
Publication Number | Publication Date |
---|---|
HRP20100014T1 true HRP20100014T1 (hr) | 2010-02-28 |
Family
ID=37686002
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HR20100014T HRP20100014T1 (hr) | 2005-09-01 | 2010-01-11 | Uporaba il-23 i il-17 antagonista u liječenju autoimune očne upalne bolesti |
Country Status (22)
Country | Link |
---|---|
US (6) | US20080199460A1 (pt) |
EP (3) | EP1933869B1 (pt) |
JP (3) | JP2009507023A (pt) |
CN (1) | CN101296706B (pt) |
AT (1) | ATE445415T1 (pt) |
AU (1) | AU2006284841B2 (pt) |
BR (1) | BRPI0615297A2 (pt) |
CA (1) | CA2621086A1 (pt) |
CY (1) | CY1110606T1 (pt) |
DE (1) | DE602006009834D1 (pt) |
DK (1) | DK1933869T3 (pt) |
ES (1) | ES2333260T3 (pt) |
HK (1) | HK1119578A1 (pt) |
HR (1) | HRP20100014T1 (pt) |
NO (1) | NO20081574L (pt) |
NZ (2) | NZ566424A (pt) |
PL (1) | PL1933869T3 (pt) |
PT (1) | PT1933869E (pt) |
RS (1) | RS51142B (pt) |
SI (1) | SI1933869T1 (pt) |
TW (2) | TWI372061B (pt) |
WO (1) | WO2007027761A2 (pt) |
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US7790862B2 (en) | 2006-06-13 | 2010-09-07 | Zymogenetics, Inc. | IL-17 and IL-23 antagonists and methods of using the same |
US7833527B2 (en) | 2006-10-02 | 2010-11-16 | Amgen Inc. | Methods of treating psoriasis using IL-17 Receptor A antibodies |
NZ579297A (en) * | 2007-02-28 | 2012-03-30 | Schering Corp | Combination therapy comprising an il-23 antagonist and a cytokine antagonist for treatment of immune disorders |
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TR201902033T4 (tr) * | 2005-06-30 | 2019-03-21 | Janssen Biotech Inc | Anti-IL-23 antikorları, bileşimleri, yöntemleri ve kullanımları. |
CN103172737A (zh) | 2005-06-30 | 2013-06-26 | Abbvie公司 | Il-12/p40结合蛋白 |
US7807160B2 (en) | 2005-08-31 | 2010-10-05 | Schering Corporation | Engineered anti-IL-23 antibodies |
MX2008008621A (es) | 2005-12-29 | 2008-11-27 | Centocor Inc | Anticuerpos anti-il-23 humanos, composiciones, metodos y usos. |
TW200815469A (en) * | 2006-06-23 | 2008-04-01 | Astrazeneca Ab | Compounds |
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2006
- 2006-08-30 JP JP2008529228A patent/JP2009507023A/ja not_active Withdrawn
- 2006-08-30 US US11/512,622 patent/US20080199460A1/en not_active Abandoned
- 2006-08-30 PT PT06813945T patent/PT1933869E/pt unknown
- 2006-08-30 BR BRPI0615297-0A patent/BRPI0615297A2/pt not_active IP Right Cessation
- 2006-08-30 NZ NZ566424A patent/NZ566424A/en not_active IP Right Cessation
- 2006-08-30 WO PCT/US2006/033840 patent/WO2007027761A2/en active Application Filing
- 2006-08-30 AU AU2006284841A patent/AU2006284841B2/en not_active Ceased
- 2006-08-30 CA CA002621086A patent/CA2621086A1/en not_active Abandoned
- 2006-08-30 PL PL06813945T patent/PL1933869T3/pl unknown
- 2006-08-30 DK DK06813945.0T patent/DK1933869T3/da active
- 2006-08-30 EP EP06813945A patent/EP1933869B1/en not_active Revoked
- 2006-08-30 DE DE602006009834T patent/DE602006009834D1/de active Active
- 2006-08-30 NZ NZ595262A patent/NZ595262A/xx not_active IP Right Cessation
- 2006-08-30 SI SI200630517T patent/SI1933869T1/sl unknown
- 2006-08-30 CN CN2006800403078A patent/CN101296706B/zh not_active Expired - Fee Related
- 2006-08-30 EP EP10180648.7A patent/EP2322219A3/en not_active Withdrawn
- 2006-08-30 ES ES06813945T patent/ES2333260T3/es active Active
- 2006-08-30 RS RSP-2009/0529A patent/RS51142B/sr unknown
- 2006-08-30 EP EP09164605A patent/EP2116258A1/en not_active Withdrawn
- 2006-08-30 AT AT06813945T patent/ATE445415T1/de active
- 2006-08-31 TW TW095132202A patent/TWI372061B/zh not_active IP Right Cessation
- 2006-08-31 TW TW101115664A patent/TWI463993B/zh not_active IP Right Cessation
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2008
- 2008-03-31 NO NO20081574A patent/NO20081574L/no not_active Application Discontinuation
- 2008-10-24 HK HK08111743.9A patent/HK1119578A1/xx not_active IP Right Cessation
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2009
- 2009-12-21 US US12/643,166 patent/US20100111954A1/en not_active Abandoned
- 2009-12-21 US US12/643,152 patent/US8524230B2/en not_active Expired - Fee Related
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2010
- 2010-01-11 HR HR20100014T patent/HRP20100014T1/hr unknown
- 2010-01-12 CY CY20101100034T patent/CY1110606T1/el unknown
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2011
- 2011-01-28 US US13/015,900 patent/US20110142831A1/en not_active Abandoned
- 2011-06-28 JP JP2011143593A patent/JP5462838B2/ja not_active Expired - Fee Related
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2013
- 2013-08-06 US US13/960,441 patent/US20130323251A1/en not_active Abandoned
- 2013-08-13 JP JP2013168006A patent/JP2014005285A/ja active Pending
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2014
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