HRP20090239T1 - 4-hydroxy tamoxifen gel formulations - Google Patents
4-hydroxy tamoxifen gel formulationsInfo
- Publication number
- HRP20090239T1 HRP20090239T1 HR20090239T HRP20090239T HRP20090239T1 HR P20090239 T1 HRP20090239 T1 HR P20090239T1 HR 20090239 T HR20090239 T HR 20090239T HR P20090239 T HRP20090239 T HR P20090239T HR P20090239 T1 HRP20090239 T1 HR P20090239T1
- Authority
- HR
- Croatia
- Prior art keywords
- hydroxy tamoxifen
- gel formulations
- tamoxifen gel
- weight
- hydroxy
- Prior art date
Links
- DODQJNMQWMSYGS-QPLCGJKRSA-N 4-[(z)-1-[4-[2-(dimethylamino)ethoxy]phenyl]-1-phenylbut-1-en-2-yl]phenol Chemical compound C=1C=C(O)C=CC=1C(/CC)=C(C=1C=CC(OCCN(C)C)=CC=1)/C1=CC=CC=C1 DODQJNMQWMSYGS-QPLCGJKRSA-N 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 238000009472 formulation Methods 0.000 title 1
- 239000008365 aqueous carrier Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000003623 enhancer Substances 0.000 abstract 1
- 230000000149 penetrating effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0041—Mammary glands, e.g. breasts, udder; Intramammary administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/14—Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/32—Antioestrogens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Dermatology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Diabetes (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP04292447A EP1647271A1 (en) | 2004-10-14 | 2004-10-14 | 4-Hydroxy tamoxifen gel formulations |
| US63835904P | 2004-12-23 | 2004-12-23 | |
| PCT/EP2005/011654 WO2006040196A1 (en) | 2004-10-14 | 2005-10-13 | 4-hydroxy tamoxifen gel formulations |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20090239T1 true HRP20090239T1 (en) | 2009-06-30 |
Family
ID=35501209
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HR20090239T HRP20090239T1 (en) | 2004-10-14 | 2009-04-22 | 4-hydroxy tamoxifen gel formulations |
Country Status (24)
| Country | Link |
|---|---|
| EP (1) | EP1799201B1 (ru) |
| JP (1) | JP5047800B2 (ru) |
| KR (1) | KR101294947B1 (ru) |
| AT (1) | ATE415156T1 (ru) |
| AU (1) | AU2005293712B2 (ru) |
| BR (1) | BRPI0518139B1 (ru) |
| CA (1) | CA2582174C (ru) |
| CY (1) | CY1110499T1 (ru) |
| DE (1) | DE602005011314D1 (ru) |
| DK (1) | DK1799201T3 (ru) |
| EA (1) | EA011295B1 (ru) |
| ES (1) | ES2318563T3 (ru) |
| GE (1) | GEP20104889B (ru) |
| HK (1) | HK1103027A1 (ru) |
| HR (1) | HRP20090239T1 (ru) |
| IL (1) | IL182298A (ru) |
| MA (1) | MA28927B1 (ru) |
| MX (1) | MX2007004371A (ru) |
| NO (1) | NO338755B1 (ru) |
| PL (1) | PL1799201T3 (ru) |
| PT (1) | PT1799201E (ru) |
| SI (1) | SI1799201T1 (ru) |
| TN (1) | TNSN07139A1 (ru) |
| WO (1) | WO2006040196A1 (ru) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10080760B2 (en) * | 2009-10-27 | 2018-09-25 | Besins Healthcare Luxembourg Sarl | Transdermal pharmaceutical compositions comprising active agents |
| KR101304536B1 (ko) * | 2011-06-03 | 2013-09-24 | 전남대학교산학협력단 | 4-하이드록시 타목시펜 유사체 또는 이의 약학적으로 허용 가능한 염을 유효성분으로 포함하는 간질환의 치료 또는 예방용 조성물 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2558373B1 (fr) * | 1984-01-20 | 1987-07-03 | Mauvais Jarvis Pierre | Medicament antioestrogene a base de 4-hydroxytamoxifene pour administration percutanee |
| DE60305068T2 (de) * | 2002-12-18 | 2007-01-11 | Laboratoires Besins International | Behandlung von mastalgie mit 4-hydroxy-tamoxifen |
| EP2050443B1 (en) * | 2002-12-18 | 2017-05-24 | Besins Healthcare Luxembourg SARL | Reduction of breast density with 4-hydroxy tamoxifen |
| EP1941871B1 (en) * | 2003-04-01 | 2014-01-08 | Besins Healthcare Luxembourg SARL | Formulations for prevention and treatment of breast cancer with 4-hydroxy tamoxifen |
| WO2005058297A1 (en) * | 2003-12-15 | 2005-06-30 | Laboratoires Besins International | Use of 4-hydroxytamoxifen for the preparation of a medicament for the treatment of gynecomastia |
| EP1579857A1 (en) * | 2004-03-22 | 2005-09-28 | Laboratoires Besins International | Chemically stable compositions of 4-hydroxy tamoxifen |
| DE602005005986T2 (de) * | 2004-03-22 | 2009-06-04 | Laboratoires Besins International | 4-hydroxytamoxifen zur behandlung und prophylaxe von benignen brusterkrankungen |
| EP1579856A1 (en) * | 2004-03-22 | 2005-09-28 | Laboratoires Besins International | Treatment and prevention of benign breast disease with 4-hydroxy tamoxifen |
-
2005
- 2005-10-13 EP EP05803579A patent/EP1799201B1/en active Active
- 2005-10-13 JP JP2007536126A patent/JP5047800B2/ja active Active
- 2005-10-13 AU AU2005293712A patent/AU2005293712B2/en active Active
- 2005-10-13 PT PT05803579T patent/PT1799201E/pt unknown
- 2005-10-13 CA CA2582174A patent/CA2582174C/en active Active
- 2005-10-13 PL PL05803579T patent/PL1799201T3/pl unknown
- 2005-10-13 GE GEAP20059987A patent/GEP20104889B/en unknown
- 2005-10-13 MX MX2007004371A patent/MX2007004371A/es active IP Right Grant
- 2005-10-13 WO PCT/EP2005/011654 patent/WO2006040196A1/en active Application Filing
- 2005-10-13 ES ES05803579T patent/ES2318563T3/es active Active
- 2005-10-13 KR KR1020077008384A patent/KR101294947B1/ko active IP Right Grant
- 2005-10-13 SI SI200530597T patent/SI1799201T1/sl unknown
- 2005-10-13 EA EA200700834A patent/EA011295B1/ru unknown
- 2005-10-13 BR BRPI0518139-9A patent/BRPI0518139B1/pt active IP Right Grant
- 2005-10-13 AT AT05803579T patent/ATE415156T1/de active
- 2005-10-13 DK DK05803579T patent/DK1799201T3/da active
- 2005-10-13 DE DE602005011314T patent/DE602005011314D1/de active Active
-
2007
- 2007-03-29 IL IL182298A patent/IL182298A/en active IP Right Grant
- 2007-04-09 MA MA29815A patent/MA28927B1/fr unknown
- 2007-04-13 TN TNP2007000139A patent/TNSN07139A1/fr unknown
- 2007-05-14 NO NO20072463A patent/NO338755B1/no unknown
- 2007-10-18 HK HK07111311.2A patent/HK1103027A1/xx unknown
-
2009
- 2009-02-20 CY CY20091100201T patent/CY1110499T1/el unknown
- 2009-04-22 HR HR20090239T patent/HRP20090239T1/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL182298A (en) | 2013-01-31 |
| TNSN07139A1 (en) | 2008-11-21 |
| DE602005011314D1 (de) | 2009-01-08 |
| AU2005293712B2 (en) | 2011-04-21 |
| WO2006040196A1 (en) | 2006-04-20 |
| KR20070068366A (ko) | 2007-06-29 |
| JP2008525316A (ja) | 2008-07-17 |
| PT1799201E (pt) | 2009-02-26 |
| BRPI0518139B1 (pt) | 2021-10-13 |
| EP1799201B1 (en) | 2008-11-26 |
| BRPI0518139A (pt) | 2008-10-28 |
| ES2318563T3 (es) | 2009-05-01 |
| CA2582174C (en) | 2013-01-29 |
| CY1110499T1 (el) | 2015-04-29 |
| CA2582174A1 (en) | 2006-04-20 |
| PL1799201T3 (pl) | 2009-05-29 |
| MA28927B1 (fr) | 2007-10-01 |
| EA200700834A1 (ru) | 2007-10-26 |
| EP1799201A1 (en) | 2007-06-27 |
| AU2005293712A1 (en) | 2006-04-20 |
| JP5047800B2 (ja) | 2012-10-10 |
| MX2007004371A (es) | 2007-06-07 |
| NO20072463L (no) | 2007-05-14 |
| DK1799201T3 (da) | 2009-03-30 |
| IL182298A0 (en) | 2007-07-24 |
| GEP20104889B (en) | 2010-02-10 |
| SI1799201T1 (sl) | 2009-06-30 |
| HK1103027A1 (en) | 2007-12-14 |
| EA011295B1 (ru) | 2009-02-27 |
| ATE415156T1 (de) | 2008-12-15 |
| NO338755B1 (no) | 2016-10-17 |
| KR101294947B1 (ko) | 2013-08-09 |
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