HRP20090188T1 - Oxaliplatin with a low content of accompanying impurities and a method for preparation thereof - Google Patents
Oxaliplatin with a low content of accompanying impurities and a method for preparation thereofInfo
- Publication number
- HRP20090188T1 HRP20090188T1 HR20090188T HRP20090188T HRP20090188T1 HR P20090188 T1 HRP20090188 T1 HR P20090188T1 HR 20090188 T HR20090188 T HR 20090188T HR P20090188 T HRP20090188 T HR P20090188T HR P20090188 T1 HRP20090188 T1 HR P20090188T1
- Authority
- HR
- Croatia
- Prior art keywords
- water
- oxaliplatin
- preparation
- treated
- solid phase
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
- C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
- C07F15/0086—Platinum compounds
- C07F15/0093—Platinum compounds without a metal-carbon linkage
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Inorganic Compounds Of Heavy Metals (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CZ20032855A CZ297703B6 (cs) | 2003-10-17 | 2003-10-17 | Oxaliplatina s nízkým obsahem doprovodných necistot a zpusob její výroby |
| PCT/CZ2004/000068 WO2005035544A1 (en) | 2003-10-17 | 2004-10-14 | Oxaliplatin with a low content of accompanying impurities and a method for preparation thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20090188T1 true HRP20090188T1 (en) | 2009-05-31 |
Family
ID=34427805
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HR20090188T HRP20090188T1 (en) | 2003-10-17 | 2004-10-14 | Oxaliplatin with a low content of accompanying impurities and a method for preparation thereof |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US7351846B2 (cs) |
| EP (1) | EP1680434B1 (cs) |
| JP (1) | JP2007508330A (cs) |
| CN (1) | CN100408588C (cs) |
| AT (1) | ATE419259T1 (cs) |
| CA (1) | CA2540374A1 (cs) |
| CZ (1) | CZ297703B6 (cs) |
| DE (1) | DE602004018812D1 (cs) |
| ES (1) | ES2320554T3 (cs) |
| HR (1) | HRP20090188T1 (cs) |
| PL (2) | PL366974A1 (cs) |
| RU (1) | RU2345085C2 (cs) |
| WO (1) | WO2005035544A1 (cs) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007512318A (ja) * | 2003-11-25 | 2007-05-17 | プラトコ・テクノロジーズ・（プロプライエタリー）・リミテッド | 白金（ｉｉ）錯体並びに該錯体の製法及び使用 |
| US7393847B2 (en) | 2004-03-13 | 2008-07-01 | Boehringer Ingleheim International Gmbh | Imidazopyridazinediones, their preparation and their use as pharmaceutical compositions |
| US7208616B2 (en) | 2004-07-12 | 2007-04-24 | Sicor, Inc. | Cis-diiodo-(trans-L-1,2-cyclohexanediamine) platinum (II) complex and processes for preparing high purity oxaliplatin |
| DE602005014559D1 (de) * | 2004-09-01 | 2009-07-02 | Platco Technologies Proprietar | Herstellung von platin(ii)-komplexen |
| EP1874290A1 (en) | 2005-04-09 | 2008-01-09 | Vuab Pharma A. S. | A process for the preparation of an oxaliplatin preparation |
| US7956208B2 (en) * | 2006-01-30 | 2011-06-07 | Platco Technologies (Proprietary) Limited | Preparation of platinum (II) complexes |
| DE602006018205D1 (de) | 2006-06-08 | 2010-12-23 | Vuab Pharma A S | Verfahren zur herstellung eines oxaliplatins |
| US20090076139A1 (en) * | 2007-09-19 | 2009-03-19 | Protia, Llc | Deuterium-enriched oxalplatin |
| CN101343291B (zh) * | 2008-08-25 | 2011-05-18 | 南京臣功制药有限公司 | 奥沙利铂的制备方法 |
| EP2208731B1 (en) | 2009-06-26 | 2012-08-15 | Umicore AG & Co. KG | Process for preparation of 1,2-diamino-cyclohexane-platinum(II) complexes |
| CN101723988B (zh) * | 2009-12-16 | 2012-07-04 | 南京东捷药业有限公司 | 一种杂质含量极低的奥沙利铂的制备方法 |
| CN106957340A (zh) * | 2017-05-10 | 2017-07-18 | 荆楚理工学院 | 一种奥沙利铂的合成方法 |
| EP3845544B1 (en) | 2018-09-01 | 2023-11-15 | Beijing Showby Pharmaceutical Co., Ltd. | Phosphate of platinum compound and preparation method therefor |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6041077B2 (ja) * | 1976-09-06 | 1985-09-13 | 喜徳 喜谷 | １，２‐ジアミノシクロヘキサン異性体のシス白金（２）錯体 |
| JPH0776230B2 (ja) * | 1992-01-13 | 1995-08-16 | 田中貴金属工業株式会社 | 白金化合物の製造方法 |
| JPH05301884A (ja) * | 1992-04-22 | 1993-11-16 | Tanaka Kikinzoku Kogyo Kk | 白金錯化合物の製造方法 |
| JP3025602B2 (ja) * | 1993-05-21 | 2000-03-27 | デビオファーム エス．アー． | 光学的に高純度なシス−オキザラート（トランス−ｌ−１，２−シクロヘキサンジアミン）白金（ＩＩ）錯体の製造方法 |
| WO2003004505A1 (en) * | 2001-07-02 | 2003-01-16 | Debiopharm S.A. | Oxaliplatin active substance with a very low content of oxalic acid |
| CZ294668B6 (cs) * | 2001-12-10 | 2005-02-16 | Pliva Lachema A. S. | Způsob výroby oxaliplatiny |
-
2003
- 2003-10-17 CZ CZ20032855A patent/CZ297703B6/cs not_active IP Right Cessation
-
2004
- 2004-04-05 PL PL04366974A patent/PL366974A1/xx not_active Application Discontinuation
- 2004-10-14 CN CNB2004800299427A patent/CN100408588C/zh not_active Expired - Fee Related
- 2004-10-14 EP EP04762320A patent/EP1680434B1/en not_active Expired - Lifetime
- 2004-10-14 RU RU2006116512/04A patent/RU2345085C2/ru active
- 2004-10-14 ES ES04762320T patent/ES2320554T3/es not_active Expired - Lifetime
- 2004-10-14 WO PCT/CZ2004/000068 patent/WO2005035544A1/en active Application Filing
- 2004-10-14 DE DE602004018812T patent/DE602004018812D1/de not_active Expired - Lifetime
- 2004-10-14 PL PL04762320T patent/PL1680434T3/pl unknown
- 2004-10-14 JP JP2006534563A patent/JP2007508330A/ja active Pending
- 2004-10-14 AT AT04762320T patent/ATE419259T1/de not_active IP Right Cessation
- 2004-10-14 HR HR20090188T patent/HRP20090188T1/xx unknown
- 2004-10-14 CA CA002540374A patent/CA2540374A1/en not_active Abandoned
- 2004-10-14 US US10/595,286 patent/US7351846B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JP2007508330A (ja) | 2007-04-05 |
| EP1680434A1 (en) | 2006-07-19 |
| ES2320554T3 (es) | 2009-05-25 |
| CZ20032855A3 (cs) | 2005-05-18 |
| RU2006116512A (ru) | 2007-11-27 |
| CZ297703B6 (cs) | 2007-03-07 |
| US7351846B2 (en) | 2008-04-01 |
| DE602004018812D1 (de) | 2009-02-12 |
| US20070073074A1 (en) | 2007-03-29 |
| CN1867574A (zh) | 2006-11-22 |
| CA2540374A1 (en) | 2005-04-21 |
| CN100408588C (zh) | 2008-08-06 |
| PL366974A1 (en) | 2005-04-18 |
| EP1680434B1 (en) | 2008-12-31 |
| RU2345085C2 (ru) | 2009-01-27 |
| WO2005035544A8 (en) | 2005-09-09 |
| PL1680434T3 (pl) | 2009-07-31 |
| WO2005035544A1 (en) | 2005-04-21 |
| ATE419259T1 (de) | 2009-01-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HRP20090188T1 (en) | Oxaliplatin with a low content of accompanying impurities and a method for preparation thereof | |
| Morgan et al. | 201. Researches on residual affinity and co-ordination. Part XXXIV. 2: 2′-Dipyridyl platinum salts | |
| Brown et al. | Oxidation of coordinated diamines in bis (2, 2'-bipyridine) complexes of ruthenium | |
| JP3432778B2 (ja) | 活性酸素消去剤の濃縮液、その製造方法および活性酸素消去剤パウダー | |
| Arago et al. | Interaction of" long" open-chain polyazaalkanes with hydrogen and copper (II) ions | |
| Schoellhorn et al. | Diplatinum (III) complexes with bridging 1-methyluracil ligands in head-tail arrangement: synthesis, structures, and solution behavior | |
| Amiri et al. | Highly selective transport of silver ion through a supported liquid membrane using calix [4] pyrroles as suitable ion carriers | |
| JP5603394B2 (ja) | セシウムを含む廃液の処理方法 | |
| Alguacil et al. | Uphill permeation of chromium (VI) using Cyanex 921 as ionophore across an immobilized liquid membrane | |
| RU2000128647A (ru) | Комплексное соединение платины, способы их получения, фармацевтическая композиция | |
| Elving et al. | Spectrophotometric, Polarographic and Solubility Behavior of the Chelate Compounds of the Group IVB Metals with Aromatic N-Nitrosohydroxylamines | |
| CN103923107A (zh) | 金刚烷基吡啶配合物、中间体及其制备方法和应用 | |
| Frost et al. | Nature and cumulative stability constants of copper (I) complexes of some substituted thioureas | |
| Villaescusa et al. | EXTRACTION OF GOLD (III) FROM HYDROCHLORIC ACID SOLUTIONS BY Tri-n-DODECYLAMMONIUM CHLORIDE IN TOLUENE. ESTIMATION OF THE INTERACTION COEFFICIENT BETWEEN AuCl4 and H+. | |
| JPH1085759A (ja) | 滅菌用浄化剤の製造方法 | |
| Margalit et al. | Chemical and biological properties of pentaammineruthenium-bleomycin complexes | |
| CN110590676B (zh) | 用于苯-甲醇体系分离1-辛基-3-甲基咪唑乳酸盐离子液体方法 | |
| JP2008510749A5 (cs) | ||
| Lemma et al. | Investigation of interaction between human hemoglobin A0 and platinum anticancer drugs by capillary isoelectric focusing with whole column imaging detection | |
| JPS585700B2 (ja) | ヨウエキカラジユウキンゾク オヨビ ハクキンイガイノ センイキンゾクオジヨキヨスルホウホウ | |
| FR2836144B1 (fr) | Procede de traitement d'une solution organique d'imide porteur de groupe sulfonyle | |
| Binbuga et al. | Determination of the stability constants for the binding of sulfonated morin with Fe2+ | |
| Linder et al. | Formation constants for the hypoxanthine-and allopurinol-proton and nickel (II) systems | |
| GB942074A (en) | Purification of demethylchlortetracycline | |
| RU2003114755A (ru) | Способ получения производных тиазола, обладающих пестицидной активностью |