HRP20070030T3 - Derivatives of benzothiazine and benzothiadiazine, procedure for their preparation and pharmaceutical compositions containing them - Google Patents
Derivatives of benzothiazine and benzothiadiazine, procedure for their preparation and pharmaceutical compositions containing themInfo
- Publication number
- HRP20070030T3 HRP20070030T3 HR20070030T HRP20070030T HRP20070030T3 HR P20070030 T3 HRP20070030 T3 HR P20070030T3 HR 20070030 T HR20070030 T HR 20070030T HR P20070030 T HRP20070030 T HR P20070030T HR P20070030 T3 HRP20070030 T3 HR P20070030T3
- Authority
- HR
- Croatia
- Prior art keywords
- group
- straight
- branched alkyl
- hydrogen atom
- alkyl group
- Prior art date
Links
- UJVBZCCNLAAMOV-UHFFFAOYSA-N 2h-1,2-benzothiazine Chemical class C1=CC=C2C=CNSC2=C1 UJVBZCCNLAAMOV-UHFFFAOYSA-N 0.000 title 1
- HAVZTGSQJIEKPI-UHFFFAOYSA-N benzothiadiazine Chemical compound C1=CC=C2C=NNSC2=C1 HAVZTGSQJIEKPI-UHFFFAOYSA-N 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 9
- 125000000217 alkyl group Chemical group 0.000 abstract 8
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 125000005843 halogen group Chemical group 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- 125000000623 heterocyclic group Chemical group 0.000 abstract 2
- 229910052757 nitrogen Inorganic materials 0.000 abstract 2
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 2
- HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 abstract 1
- 101100134929 Gallus gallus COR9 gene Proteins 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0307118A FR2856065B1 (fr) | 2003-06-13 | 2003-06-13 | Nouveaux derives de benzothiazine et benzothiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20070030T3 true HRP20070030T3 (en) | 2007-08-31 |
Family
ID=33186482
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HR20070030T HRP20070030T3 (en) | 2003-06-13 | 2007-02-01 | Derivatives of benzothiazine and benzothiadiazine, procedure for their preparation and pharmaceutical compositions containing them |
Country Status (28)
| Country | Link |
|---|---|
| US (2) | US7253162B2 (es) |
| EP (1) | EP1486503B1 (es) |
| JP (1) | JP2005002114A (es) |
| KR (1) | KR100586683B1 (es) |
| CN (1) | CN1277823C (es) |
| AR (1) | AR044672A1 (es) |
| AT (1) | ATE344265T1 (es) |
| AU (1) | AU2004202586A1 (es) |
| BR (1) | BRPI0401956A (es) |
| CA (1) | CA2470263A1 (es) |
| CY (1) | CY1105939T1 (es) |
| DE (1) | DE602004002990T2 (es) |
| DK (1) | DK1486503T3 (es) |
| EA (1) | EA008797B1 (es) |
| EG (1) | EG24207A (es) |
| ES (1) | ES2276249T3 (es) |
| FR (1) | FR2856065B1 (es) |
| GE (1) | GEP20063815B (es) |
| HK (1) | HK1071750A1 (es) |
| HR (1) | HRP20070030T3 (es) |
| MA (1) | MA27092A1 (es) |
| MX (1) | MXPA04005580A (es) |
| NO (1) | NO20042422L (es) |
| NZ (1) | NZ533472A (es) |
| PL (1) | PL1486503T3 (es) |
| PT (1) | PT1486503E (es) |
| SG (1) | SG148023A1 (es) |
| SI (1) | SI1486503T1 (es) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2879201B1 (fr) * | 2004-12-10 | 2007-02-16 | Servier Lab | Nouveaux derives de benzothiazine et benzothiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| US7939528B2 (en) | 2005-10-13 | 2011-05-10 | Glaxosmithkline Llc | Heterocycle compounds |
| JP2010502706A (ja) * | 2006-09-07 | 2010-01-28 | ミレニアム・ファーマシューティカルズ・インコーポレイテッド | キナーゼ阻害活性を有するフェネチルアミド誘導体 |
| GB0821166D0 (en) * | 2008-11-19 | 2008-12-24 | Glaxo Group Ltd | Compounds |
| FR2955106B1 (fr) * | 2010-01-08 | 2011-12-23 | Servier Lab | Nouveaux derives de benzothiadiazines cyclopropylees, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| EP2813508B1 (en) * | 2012-02-08 | 2018-01-31 | Takeda Pharmaceutical Company Limited | Heterocyclic compound and use thereof |
| WO2019130229A1 (en) * | 2017-12-28 | 2019-07-04 | Mylan Laboratories Ltd | Methods and intermediates for preparing rucaparib |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1377693A (fr) * | 1962-12-06 | 1964-11-06 | Geigy Ag J R | Nouveaux composés dibenzo [1.2] thiaziniques et produits pesticides qui en contiennent |
| FR2722502B1 (fr) * | 1994-07-12 | 1996-08-23 | Adir | Nouveau derive de benzothiadiazine, son procede depreparation et les compositions pharmaceutiques qui le contiennent |
| ZA991301B (en) * | 1998-02-18 | 1999-09-13 | Neurosearch As | Glutamate receptor modulators. |
| FR2823753B1 (fr) * | 2001-04-18 | 2004-07-16 | Servier Lab | Nouveau procede de synthese de la (3as)-5,5-dioxo-2,3,3a, 4-tetrahydro-1h-pyrrolo [2,1-c] [1,2,4] benzothiadiazine |
| FR2833956B1 (fr) * | 2001-12-21 | 2004-01-30 | Servier Lab | Nouveaux derives de benzothiazine et de benzothiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| FR2833950B1 (fr) * | 2001-12-21 | 2005-12-16 | Servier Lab | Nouveaux derives de benzothiazine et de benzothiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
-
2003
- 2003-06-13 FR FR0307118A patent/FR2856065B1/fr not_active Expired - Fee Related
-
2004
- 2004-06-04 MA MA27721A patent/MA27092A1/fr unknown
- 2004-06-07 SG SG200404677-7A patent/SG148023A1/en unknown
- 2004-06-09 SI SI200430111T patent/SI1486503T1/sl unknown
- 2004-06-09 EP EP04291435A patent/EP1486503B1/fr not_active Expired - Lifetime
- 2004-06-09 DE DE602004002990T patent/DE602004002990T2/de not_active Expired - Fee Related
- 2004-06-09 AT AT04291435T patent/ATE344265T1/de not_active IP Right Cessation
- 2004-06-09 MX MXPA04005580A patent/MXPA04005580A/es active IP Right Grant
- 2004-06-09 DK DK04291435T patent/DK1486503T3/da active
- 2004-06-09 ES ES04291435T patent/ES2276249T3/es not_active Expired - Lifetime
- 2004-06-09 PT PT04291435T patent/PT1486503E/pt unknown
- 2004-06-09 PL PL04291435T patent/PL1486503T3/pl unknown
- 2004-06-10 NO NO20042422A patent/NO20042422L/no not_active Application Discontinuation
- 2004-06-10 EG EG2004060261A patent/EG24207A/xx active
- 2004-06-10 US US10/865,184 patent/US7253162B2/en not_active Expired - Fee Related
- 2004-06-11 GE GE5557A patent/GEP20063815B/en unknown
- 2004-06-11 EA EA200400666A patent/EA008797B1/ru not_active IP Right Cessation
- 2004-06-11 AU AU2004202586A patent/AU2004202586A1/en not_active Abandoned
- 2004-06-11 AR ARP040102023A patent/AR044672A1/es unknown
- 2004-06-11 CA CA002470263A patent/CA2470263A1/fr not_active Abandoned
- 2004-06-11 NZ NZ533472A patent/NZ533472A/en unknown
- 2004-06-11 KR KR1020040042991A patent/KR100586683B1/ko not_active IP Right Cessation
- 2004-06-14 BR BR0401956-3A patent/BRPI0401956A/pt not_active IP Right Cessation
- 2004-06-14 CN CNB2004100482744A patent/CN1277823C/zh not_active Expired - Fee Related
- 2004-06-14 JP JP2004175278A patent/JP2005002114A/ja active Pending
-
2005
- 2005-05-30 HK HK05104495A patent/HK1071750A1/xx not_active IP Right Cessation
-
2007
- 2007-01-16 CY CY20071100074T patent/CY1105939T1/el unknown
- 2007-02-01 HR HR20070030T patent/HRP20070030T3/xx unknown
- 2007-06-27 US US11/823,439 patent/US7423034B2/en not_active Expired - Fee Related
Also Published As
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